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88 条记录 (耗时 0.039 秒)

    Bicycloaniline derivative
    3.
    发明授权
    Bicycloaniline derivative 有权
    双苯胺衍生物

    公开(公告)号：US08436004B2

    公开(公告)日：2013-05-07

    申请号：US12663729

    申请日：2008-06-12

    申请人： Makoto Bamba ,  Hidetomo Furuyama ,  Kenji Niiyama ,  Toshihiro Sakamoto ,  Satoshi Sunami ,  Keiji Takahashi ,  Fuyuki Yamamoto ,  Takashi Yoshizumi

    发明人： Makoto Bamba ,  Hidetomo Furuyama ,  Kenji Niiyama ,  Toshihiro Sakamoto ,  Satoshi Sunami ,  Keiji Takahashi ,  Fuyuki Yamamoto ,  Takashi Yoshizumi

    IPC分类号： A01N43/90 ,  A61K31/519 ,  C07D487/00

    CPC分类号： C07D487/04 ,  A61K31/522 ,  A61K31/5415 ,  A61K31/55 ,  A61K45/06 ,  C07D519/00

    摘要： The invention relates to a compound of a general formula (I): wherein A1 and A2 each mean a nitrogen atom or an optionally-substituted methine group; Ring B means a 5-membered to 7-membered aliphatic ring, or a spiro or bicyclo ring formed from the aliphatic ring and any other 3-membered to 7-membered aliphatic ring; R1 means a hydrogen atom, or an optionally-substituted C1-C6 alkyl group, or an optionally-substituted aryl, aralkyl or heteroaryl group; R2 means an optionally-substituted aryl, aralkyl or heteroaryl group; and X means a group of ═NH or ═O, etc. Based on its excellent Wee1 kinase-inhibitory effect, the compound of the invention has cell growth-inhibitory effect and has an additive/synergistic effect with any other anticancer agent, and is therefore useful in the field of medicine.

    摘要翻译： 本发明涉及通式（I）的化合物：其中A1和A2各自表示氮原子或任选取代的次甲基; 环B表示由脂族环和任何其它3元至7元脂肪环形成的5元至7元脂族环或螺环或双环; R 1表示氢原子或任选取代的C 1 -C 6烷基，或任选取代的芳基，芳烷基或杂芳基; R 2表示任选取代的芳基，芳烷基或杂芳基; X表示一组= NH或= O等。基于其优异的Wee1激酶抑制作用，本发明化合物具有细胞生长抑制作用，与​​任何其他抗癌剂具有添加/协同作用，并且 因此在医学领域是有用的。

    OCCLUSAL WEAR EVALUATION APPARATUS AND OCCLUSAL WEAR EVALUATION METHOD
    4.
    发明申请
    OCCLUSAL WEAR EVALUATION APPARATUS AND OCCLUSAL WEAR EVALUATION METHOD 审中-公开
    OCCLUSAL WEAR EVALUATION装置和OCCLUSAL WEAR EVALUATION方法

    公开(公告)号：US20130054190A1

    公开(公告)日：2013-02-28

    申请号：US13589434

    申请日：2012-08-20

    申请人： Yusei KADOBAYASHI ,  Masako Shigezawa ,  Keiji Takahashi

    发明人： Yusei KADOBAYASHI ,  Masako Shigezawa ,  Keiji Takahashi

    IPC分类号： G06F15/00

    CPC分类号： A61C19/05 ,  A61C11/00 ,  A61C13/0004 ,  A61C19/04 ,  G16H50/50

    摘要： An occlusal wear evaluation apparatus capable of evaluating quantitatively an occlusal wear of a used denture reads three dimensional data of a denture before use and three dimensional data of the denture after use, calculates a difference in a set value of an articulator allowing the maxillary dental arch and the mandibular dental arch of the denture to occlude between the denture before use and the denture after use, by way of simulating movements of a jaw in the articulator with the three dimensional data of the denture before use and the three dimensional data of the denture after use, and indicates the calculated difference.

    摘要翻译： 一种咬合磨损评价装置，其能够定量评价使用过的假牙的咬合磨损，在使用前读取义齿的三维数据和使用后的义齿的三维数据，计算允许上颌牙弓的咬合器的设定值的差异 以及义齿下颌牙弓在使用前与义齿之间闭合，并且在使用之后通过假牙的三维数据和假牙的三维数据模拟咬合器中的钳口的运动 使用后，表示计算出的差值。

    OCCLUSION EVALUATION APPARATUS AND OCCLUSION EVALUATION METHOD
    5.
    发明申请
    OCCLUSION EVALUATION APPARATUS AND OCCLUSION EVALUATION METHOD 有权
    OCCLUSION评估和评估方法

    公开(公告)号：US20130045458A1

    公开(公告)日：2013-02-21

    申请号：US13569581

    申请日：2012-08-08

    申请人： Yusei Kadobayashi ,  Masako Shigezawa ,  Keiji Takahashi

    发明人： Yusei Kadobayashi ,  Masako Shigezawa ,  Keiji Takahashi

    IPC分类号： A61C19/05

    CPC分类号： A61C9/0053 ,  A61C19/05

    摘要： An occlusion evaluation apparatus capable of evaluating a masticatory ability depending on an occlusal geometry of teeth without actually used by a human subject, reads three dimensional data of geometries of maxillary molar teeth 1, 2, 3, 4 and mandibular molar teeth 5, 6, 7, 8, and specifies a geometry of a fluxion space Va defined by a plane Sa which includes two adjacent contact points Pa between the maxillary molar teeth 1, 2, 3, 4 and mandibular molar teeth 5, 6, 7, 8 and which is perpendicular to the occlusal plane, the occlusal surfaces of the maxillary molar teeth 1, 2, 3, 4, and the occlusal surfaces of the mandibular molar teeth 5, 6, 7, 8.

    摘要翻译： 一种咬合评价装置，其能够根据牙齿的咬合面几何形状来评价咀嚼能力，而实际上不被人体使用，能够读取上颌牙齿1,2,3,4和下颌牙齿5,6的几何形状的三维数据， 如图7,8所示，并且规定由平面Sa限定的流动空间Va的几何形状，该平面Sa包括上颌齿臼齿1,2,3,4和下颌齿臼齿5,6,7,8之间的两个相邻接触点Pa，并且 垂直于咬合平面，上颌牙齿1,2,3和4的咬合面以及下颌牙摩擦牙5,6,7,8的咬合面。

    Aluminosilicate glass and color adapting composition for ceramics
    6.
    发明授权
    Aluminosilicate glass and color adapting composition for ceramics 有权
    铝硅酸盐玻璃和陶瓷颜色适应组合物

    公开(公告)号：US08304356B2

    公开(公告)日：2012-11-06

    申请号：US13398885

    申请日：2012-02-17

    申请人： Yukio Fukatani ,  Keiji Takahashi ,  Ryuichi Yoshimoto

    发明人： Yukio Fukatani ,  Keiji Takahashi ,  Ryuichi Yoshimoto

    IPC分类号： A61C13/083 ,  A61C13/00 ,  C03C8/22 ,  C03C3/091

    CPC分类号： C03C3/091 ,  A61K6/0094 ,  A61K6/0276 ,  C03C4/0021 ,  C03C8/02 ,  C03C8/14

    摘要： The present invention relates to a color adapting composition used for coloring and color adapting porcelain for ceramic crown such as dental restorations and prosthetics, and aluminosilicate glass appropriate for using in a color adapting composition. More specifically, a color adapting composition for dental porcelains are prepared by blending two or more kinds of glass frits having different sintering temperatures from each other and an inorganic pigment or a colored glass obtained by previously dispersing inorganic pigments in glass.

    摘要翻译： 本发明涉及一种用于陶瓷冠的着色和着色适应性瓷的修色组合物，例如牙科修复体和假肢，以及适用于适应颜色的组合物的铝硅酸盐玻璃。 更具体地说，通过将两种或更多种具有不同烧结温度的玻璃料混合并将无机颜料或通过预先将无机颜料分散在玻璃中得到的着色玻璃混合来制备用于牙科瓷器的调色组合物。

    Engine and personal watercraft
    8.
    发明授权
    Engine and personal watercraft 有权
    发动机和个人船只

    公开(公告)号：US07832383B2

    公开(公告)日：2010-11-16

    申请号：US11725155

    申请日：2007-03-15

    申请人： Atsufumi Ozaki ,  Keiji Takahashi

    发明人： Atsufumi Ozaki ,  Keiji Takahashi

    IPC分类号： F02B33/00

    CPC分类号： F02B33/32 ,  F02B29/0475 ,  F02B33/44 ,  F02B61/04 ,  Y02T10/146

    摘要： An engine for a personal watercraft that is equipped with a supercharging machine, including a pressure release device that is configured to, when a pressure in a region of an air-intake passage of the engine that is located upstream of a throttle valve in an intake-air flow direction exceeds a predetermined value, release the pressure outside the air-intake passage.

    摘要翻译： 一种用于个人船舶的发动机，其配备有增压机，包括压力释放装置，该压力释放装置构造成当位于进气口中的节气门上游的发动机的进气通道的区域中的压力时 空气流动方向超过预定值，释放进气通道外部的压力。

    Voltage controller for alternator of vehicle
    10.
    发明授权
    Voltage controller for alternator of vehicle 有权
    汽车交流发电机电压控制器

    公开(公告)号：US07586222B2

    公开(公告)日：2009-09-08

    申请号：US11509690

    申请日：2006-08-25

    申请人： Keiji Takahashi

    发明人： Keiji Takahashi

    IPC分类号： H02K19/36 ,  H02K9/00

    CPC分类号： H02K19/365

    摘要： A voltage controller has a control circuit and a heat radiating member attached to the circuit. The circuit controls a voltage of electric power generated in an alternator of a vehicle while generating heat. The member has a first surface and a second surface. The second surface of the member is formed in a smooth shape having no protrusions or hollows. A cooling wind flows on the second surface. The member receives the heat from the control circuit through the first surface and radiates the heat from the second surface to the wind.

    摘要翻译： 电压控制器具有附接到电路的控制电路和散热构件。 该电路控制在车辆的交流发电机中产生的电力的电压，同时产生热量。 该构件具有第一表面和第二表面。 构件的第二表面形成为没有突起或中空的平滑形状。 冷却风在第二表面上流动。 该构件通过第一表面接收来自控制电路的热量，并将热量从第二表面辐射到风中。