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    Biochemical analysis unit
    4.
    发明授权
    Biochemical analysis unit 失效
    生化分析单位

    公开(公告)号：US07262048B2

    公开(公告)日：2007-08-28

    申请号：US10800676

    申请日：2004-03-16

    申请人： Kenji Nakajima ,  Akifumi Kato

    发明人： Kenji Nakajima ,  Akifumi Kato

    IPC分类号： C12M1/34

    CPC分类号： G01N33/54366 ,  B01L3/502 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0861 ,  B01L2300/0877 ,  B01L2400/0487

    摘要： A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.

    摘要翻译： 生化分析单元包括具有孔的基板和多孔吸附材料，其填充在每个孔中并形成每个吸附区域。 每个吸附区域设置有具有平均孔径相对较小的孔的层和具有平均孔径相对较大的孔的层。 在构成每个吸附区域的层与构成相邻吸附区域的层在基板的一个表面连接的情况下，生化分析单元还包括用于吸收信号的信号吸收层 其通过位于基板下方的层，从而从一定孔向邻近的孔传播。

    Biochemical analysis unit
    5.
    发明授权
    Biochemical analysis unit 失效
    生化分析单位

    公开(公告)号：US07713729B2

    公开(公告)日：2010-05-11

    申请号：US11782786

    申请日：2007-07-25

    申请人： Kenji Nakajima ,  Akifumi Kato

    发明人： Kenji Nakajima ,  Akifumi Kato

    IPC分类号： C12M1/34

    CPC分类号： G01N33/54366 ,  B01L3/502 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0861 ,  B01L2300/0877 ,  B01L2400/0487

    摘要： A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.

    摘要翻译： 生化分析单元包括具有孔的基板和多孔吸附材料，其填充在每个孔中并形成每个吸附区域。 每个吸附区域设置有具有平均孔径相对较小的孔的层和具有平均孔径相对较大的孔的层。 在构成每个吸附区域的层与构成相邻吸附区域的层在基板的一个表面连接的情况下，生化分析单元还包括用于吸收信号的信号吸收层 其通过位于基板下方的层，从而从一定孔向邻近的孔传播。

    BIOCHEMICAL ANALYSIS UNIT
    7.
    发明申请
    BIOCHEMICAL ANALYSIS UNIT 失效
    生物化学分析单位

    公开(公告)号：US20070274859A1

    公开(公告)日：2007-11-29

    申请号：US11782786

    申请日：2007-07-25

    申请人： Kenji Nakajima ,  Akifumi Kato

    发明人： Kenji Nakajima ,  Akifumi Kato

    IPC分类号： B01J19/00

    CPC分类号： G01N33/54366 ,  B01L3/502 ,  B01L3/5085 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0861 ,  B01L2300/0877 ,  B01L2400/0487

    摘要： A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.

    摘要翻译： 生化分析单元包括具有孔的基板和多孔吸附材料，其填充在每个孔中并形成每个吸附区域。 每个吸附区域设置有具有平均孔径相对较小的孔的层和具有平均孔径相对较大的孔的层。 在构成每个吸附区域的层与构成相邻吸附区域的层在基板的一个表面连接的情况下，生化分析单元还包括用于吸收信号的信号吸收层 其通过位于基板下方的层，从而从一定孔向邻近的孔传播。

    Recombinant protein S composition
    9.
    发明授权
    Recombinant protein S composition 失效
    重组蛋白S组成

    公开(公告)号：US08501914B2

    公开(公告)日：2013-08-06

    申请号：US12540501

    申请日：2009-08-13

    申请人： Yutaka Kanda ,  Hiroshi Sato ,  Tsuyoshi Yamada ,  Akifumi Kato ,  Mitsuo Satoh

    发明人： Yutaka Kanda ,  Hiroshi Sato ,  Tsuyoshi Yamada ,  Akifumi Kato ,  Mitsuo Satoh

    IPC分类号： A61K38/16 ,  C12P21/02

    CPC分类号： C07K14/745 ,  A61K38/00 ,  C12P21/005

    摘要： A pharmaceutical agent for treating a disease such as inflammatory diseases, blood coagulation diseases associated with deficiency of Protein S has been required. The present invention provides a Protein S composition comprising recombinant Protein S molecules having complex type N-glycoside-linked sugar chains, wherein the Protein S has a higher binding activity to a receptor for advanced glycation end products (hereinafter referred to as “RAGE”) than native Protein S present in healthy human blood, and also has a higher ratio of sugar chains in which fucose is not bound to the complex type N-glycoside-linked sugar chains bound to Protein S than native Protein S present in healthy human blood.

    摘要翻译： 需要用于治疗诸如炎性疾病，与蛋白S缺乏相关的血液凝固疾病等疾病的药剂。 本发明提供了包含具有复合型N-糖苷连接的糖链的重组蛋白S分子的蛋白S组合物，其中蛋白S与晚期糖基化终产物的受体（以下称为“RAGE”）具有较高的结合活性， 比存在于健康人血液中的天然蛋白S高，并且与健康人血液中存在的天然蛋白S相比，岩藻糖与其与蛋白S结合的复合型N-糖苷连接的糖链不结合的糖链的比例更高。

    Production method of polymer film and production apparatus of the same
    10.
    发明申请
    Production method of polymer film and production apparatus of the same 审中-公开
    聚合物膜的制造方法及其制造装置

    公开(公告)号：US20080054515A1

    公开(公告)日：2008-03-06

    申请号：US11896840

    申请日：2007-09-06

    申请人： Akifumi Kato ,  Hidekazu Yamazaki ,  Hitoshi Ikeda

    发明人： Akifumi Kato ,  Hidekazu Yamazaki ,  Hitoshi Ikeda

    IPC分类号： B29C39/20

    CPC分类号： B29C41/26 ,  B29K2001/00 ,  B29K2001/12

    摘要： There is provided a casting drum having an outer peripheral surface provided with an electrical insulating layer. Direct-current high voltage is applied to an electrode bar disposed in an upstream side from a discharge port to discharge toward the casting drum. Bead is attracted to the charged casting drum by electrostatic attraction. Thereby, the adhesion between the bead and the casting drum is increased, and therefore the occurrence of phenomenon of air entrainment can be prevented. A wet film obtained by peeling a casting film from the casting drum is dried. Accordingly, it is possible to produce a film having few defects such as voids and high quality such as excellent smoothness at high speed and stably.

    摘要翻译： 提供了具有设置有电绝缘层的外周面的流延鼓。 直流高电压被施加到从排出口设置在上游侧的电极棒，以朝着流延鼓排出。 珠子被静电吸引吸引到充电的流延鼓上。 由此，珠与流延鼓之间的粘合力增加，因此可以防止空气夹带现象的发生。 干燥通过从流延滚筒剥离流延膜获得的湿膜。 因此，可以在高速且稳定地制造诸如空隙和高质量的缺陷如平滑性优异的膜。