公开(公告)号：US06654534B1

公开(公告)日：2003-11-25

申请号：US09709646

申请日：2000-11-13

申请人： Kelvin Prosyk ,  Ronald S Moore ,  Robert Foster ,  Marcel Boudreau

发明人： Kelvin Prosyk ,  Ronald S Moore ,  Robert Foster ,  Marcel Boudreau

IPC分类号： G02B610

CPC分类号： G02F1/025 ,  G02F2201/07 ,  G02F2203/21

摘要： An optical device, such as an electro-absorption modulator, has a waveguide formed onto a base. Electrodes adjacent the waveguide are used to selectively apply an electric field to the device in order to control the passage of light through the device. To prevent overheating of the device in a region near the point of optical entry, the electrode, which acts as a thermal conduit to dissipate heat from the waveguide is extended over the region. To prevent undesirable electrical contact between the electrode and the region, the normally electrically conducting contact layer between the electrode and the waveguide is removed in that region and replaced by an isolation dielectric.

摘要翻译： 诸如电吸收调制器的光学器件具有形成在基底上的波导。 与波导相邻的电极用于选择性地将电场施加到装置，以便控制光通过装置的通过。 为了防止在光入口附近的区域中的器件的过热，用作热导管以散发来自波导的热的电极在该区域上延伸。 为了防止电极和区域之间不期望的电接触，在该区域中去除电极和波导之间的正常导电接触层，并由隔离电介质代替。

公开(公告)号：US08943561B2

公开(公告)日：2015-01-27

申请号：US13548640

申请日：2012-07-13

申请人： Robert Foster ,  Scott Goldman ,  Mark Nielsen

发明人： Robert Foster ,  Scott Goldman ,  Mark Nielsen

IPC分类号： H04L29/06 ,  H04W12/06

CPC分类号： H04L63/0838 ,  H04L63/18 ,  H04W12/06

摘要： Systems and method for authenticating users are presented. A system can send a passkey to a user interface of a known device. A user can then send a messaging service message with the passkey from a second device to the system. After receiving the message from the user, the system can extract the passkey from the message, and compare the received passkey against the passkey originally sent to the user. The known device and the second device can each have separate and unique device identifiers.

摘要翻译： 介绍了用户认证的系统和方法。 系统可以向已知设备的用户界面发送密钥。 然后，用户可以将具有密钥的消息服务消息从第二设备发送到系统。 从用户收到消息后，系统可以从消息中提取密钥，并将接收到的密钥与最初发送给用户的密钥进行比较。 已知的设备和第二设备可以各自具有分离且唯一的设备标识符。

公开(公告)号：US20140069538A1

公开(公告)日：2014-03-13

申请号：US13998552

申请日：2013-11-08

申请人： Robert Foster

发明人： Robert Foster

IPC分类号： E03B5/00

CPC分类号： E03B5/00 ,  B08B9/08 ,  E04H4/1236 ,  Y10T137/85978 ,  Y10T137/86067

摘要： A water removal device to withdraw virtually all the water from the drain in the bottom of a swimming pool comprising an elongated lower suction or vacuum housing including a plurality of perforations or holes formed therein to receive water from a pool drain and an upper suction or vacuum source to create a suction or vacuum to draw water from the pool drain through the perforations or holes into and through the lower suction or vacuum housing to remove the water from the pool drain.

摘要翻译： 一种除水装置，用于从游泳池底部的排水口几乎抽出所有的水，包括细长的下部抽吸或真空壳体，其包括形成在其中的多个穿孔或孔，以从池排水口和上部抽吸或真空吸收水 来源以产生吸力或真空，以通过穿孔或孔从池排水口吸入水并通过下抽吸或真空壳体以从池排水口移除水。

公开(公告)号：US20060217309A1

公开(公告)日：2006-09-28

申请号：US11375532

申请日：2006-03-13

申请人： Selvaraj Naicker ,  Randall Yatscoff ,  Robert Foster

发明人： Selvaraj Naicker ,  Randall Yatscoff ,  Robert Foster

IPC分类号： A61K38/17 ,  A61K31/355 ,  A61K47/00

CPC分类号： A61K9/1075 ,  A61K9/0095 ,  A61K9/4858 ,  A61K38/13 ,  A61K47/10

摘要： The present invention relates to formulations containing cyclosporin analogs that are structurally similar to cyclosporin A, in particular isomeric mixtures of cyclosporin analogs that are structurally similar to cyclosporin A. The formulations form stable microemulsion preconcentrates and may provide superior drug bioavailability and/or may reduce one or more adverse effects associated with the administration of cyclosporin. Also disclosed are methods for using and preparing the formulations.

摘要翻译： 本发明涉及结构上类似于环孢菌素A的环孢菌素类似物的制剂，特别是在结构上类似于环孢菌素A的环孢菌素类似物的异构体混合物中。制剂形成稳定的微乳液预浓缩物，并可提供优异的药物生物利用度和/或减少一种 或更多与施用环孢菌素相关的不良反应。 还公开了使用和制备制剂的方法。

公开(公告)号：US20060095317A1

公开(公告)日：2006-05-04

申请号：US10980574

申请日：2004-11-03

申请人： Robert Brown ,  Gregory McDonald ,  Caroline Slettedahl ,  Robert Foster ,  Richard Post

发明人： Robert Brown ,  Gregory McDonald ,  Caroline Slettedahl ,  Robert Foster ,  Richard Post

IPC分类号： G06F17/60

CPC分类号： G06Q30/02 ,  G06Q10/06 ,  G06Q10/063 ,  G06Q10/0631 ,  G06Q10/06311 ,  G06Q10/063114 ,  G06Q10/063116 ,  G06Q10/063118 ,  G06Q10/06312 ,  G06Q10/06315 ,  G06Q10/06398 ,  G06Q30/0201 ,  G06Q30/0205

摘要： A system for monitoring the performance of at least one task associated with operation of a retail store. The system includes at least one monitoring device positioned and adapted to provide images of at least one location within the retail store, with each image showing at least one factor related to performance of the at least one task. A controller is adapted to obtain and store images from the at least one monitoring device. An interface is adapted to enable a user to selectively view stored images and to manually analyze the at least one factor shown in the viewed images to evaluate the performance of the at least one task.

摘要翻译： 一种用于监视与零售商店的操作相关联的至少一个任务的性能的系统。 该系统包括至少一个监控设备，其被定位并适于提供零售店内的至少一个位置的图像，每个图像显示与至少一个任务的性能有关的至少一个因素。 控制器适于获得并存储来自至少一个监视设备的图像。 接口适于使用户能够选择性地查看存储的图像并手动分析所查看的图像中所示的至少一个因素，以评估至少一个任务的性能。

公开(公告)号：US20060079466A1

公开(公告)日：2006-04-13

申请号：US11229007

申请日：2005-09-15

申请人： Mark Abel ,  Roman Szweda ,  Daniel Trepaier ,  Randall Yatscoff ,  Robert Foster

发明人： Mark Abel ,  Roman Szweda ,  Daniel Trepaier ,  Randall Yatscoff ,  Robert Foster

IPC分类号： A61K31/7052 ,  C07H17/02

CPC分类号： A61K31/7052 ,  A61K31/436 ,  C07D498/18 ,  C07H15/04 ,  C07H19/01

摘要： This invention provides modified rapamycins that have specific monosaccharide(s), oligosaccharide(s), pseudosugar(s) or derivatives thereof attached through a linker to create rapamycin carbohydrate derivatives having enhanced pharmacokinetic and/or pharmacodynamic profiles. For example, administration of the rapamycin carbohydrate derivative results in altered pharmacokinetic profiles and reduced toxicities. Thus, the present invention provides compounds with characteristics that are distinct from other drugs in its class such as rapamycin.

摘要翻译： 本发明提供了具有通过连接体连接的具有增强的药代动力学和/或药效学特征的雷帕霉素碳水化合物衍生物的特异性单糖，寡糖，假糖或其衍生物的修饰的雷帕霉素。 例如，雷帕霉素碳水化合物衍生物的施用导致药代动力学特征改变和毒性降低。 因此，本发明提供具有与其同类其他药物不同的特征的化合物，例如雷帕霉素。

公开(公告)号：US20060052290A1

公开(公告)日：2006-03-09

申请号：US11245775

申请日：2005-10-06

申请人： Salvaraj Naicker ,  Randall Yatscoff ,  Robert Foster

发明人： Salvaraj Naicker ,  Randall Yatscoff ,  Robert Foster

IPC分类号： A61K38/13 ,  C07K7/64

CPC分类号： C07K7/645 ,  A61K38/00 ,  C07B59/008 ,  C07K1/13 ,  C07K7/64 ,  Y10S530/806 ,  Y10S530/807

摘要： Cyclosporine derivatives are disclosed which possess enhanced efficacy and reduced toxicity over naturally occurring and other presently known cyclosporins and cyclosporine derivatives. The cyclosporine derivatives of the present invention are produced by chemical and isotopic substitution of the cyclosporine A (CsA) molecule by: (1) Chemical substitution and optionally deuterium substitution of amino acid 1; and (2) deuterium substitution at key sites of metabolism of the cyclosporine A molecule such as amino acids 1, 4, 9. Also disclosed are methods of producing the cyclosporine derivatives and method of producing immunosuppression with reduced toxicity with the disclosed cyclosporine derivatives.

摘要翻译： 公开了与天然存在的和其他目前已知的环孢菌素和环孢菌素衍生物相比具有增强的功效和降低的毒性的环孢菌素衍生物。 本发明的环孢菌素衍生物通过以下方式通过环孢菌素A（CsA）分子的化学和同位素取代产生：（1）氨基酸1的化学取代和任选的氘取代; 和（2）在环孢菌素A分子的代谢关键位置的氘代替，例如氨基酸1,4,9。还公开了产生环孢菌素衍生物的方法和与所公开的环孢菌素衍生物一起产生具有降低的毒性的免疫抑制的方法。

公开(公告)号：US20060037537A1

公开(公告)日：2006-02-23

申请号：US11256507

申请日：2005-10-21

申请人： Michael Lombardi ,  Glyn Reynolds ,  Robert Foster ,  Robert Rowan ,  Frederick Turner

发明人： Michael Lombardi ,  Glyn Reynolds ,  Robert Foster ,  Robert Rowan ,  Frederick Turner

IPC分类号： C23C16/00

CPC分类号： H01J37/32633 ,  C23C14/54 ,  C23C14/564 ,  H01J37/32449 ,  H01J37/32495 ,  Y10T137/0318 ,  Y10T137/0396

摘要： One or more chambers of a multi-chamber vacuum processing apparatus are provided with a high gas flow conductance path to an exhaust volume of the apparatus that is maintained at high vacuum with a high vacuum pump. Separate pumps for the one or more chambers are made unnecessary by providing such chambers with a protective deposition shield or shield set that is configured to substantially protect walls of the chamber and the gas flow conductance path from deposition and to partially impede the gas flow from the chamber through the gas flow conductance path to the exhaust volume so that the chamber can be operated at a higher pressure than that of the exhaust volume and the chambers can be operated at different pressures and without cross-contamination. Preferably, a nested set of chamber shields is used. A controller is programmed to control the processing of wafers in the chambers by controlling the supply of process gas into the chambers.

公开(公告)号：US20050072034A1

公开(公告)日：2005-04-07

申请号：US10686702

申请日：2003-10-17

申请人： Robert Foster ,  Brian Oen

发明人： Robert Foster ,  Brian Oen

IPC分类号： G09F7/12 ,  G09F3/10 ,  G09F3/00

CPC分类号： G09F7/12

摘要： A keg topping device for emplacing an advertising component on top of a keg includes a flat disc surface with an opening therein to fit the device around the mouth of a keg. The opining in the disc forms an inner rim, the perimeter of which, can be fastened to the base around the mouth of the keg by an adhesive. The advertising component is disposed on a surface of the disc member, and in place on the keg, is exposed to view from above. The surface of the disc member, surrounding the opening, is a continuous surface that is free from perforations.

摘要翻译： 用于在小桶顶部放置广告组件的小桶顶部装置包括其中具有开口的平坦盘表面，以使装置围绕小桶的口部。 在圆盘中形成一个内边缘，其内周边可通过粘合剂固定在小桶口周围的底座上。 广告组件设置在盘构件的表面上，并且在小桶上的适当位置从上方暴露出来。 围绕开口的盘构件的表面是没有穿孔的连续表面。

公开(公告)号：US20050071363A1

公开(公告)日：2005-03-31

申请号：US10675741

申请日：2003-09-30

申请人： Ping Chen ,  Robert Foster ,  Joy Underhill ,  Christine Wang ,  Quan Wang ,  Xiaodong Xia

发明人： Ping Chen ,  Robert Foster ,  Joy Underhill ,  Christine Wang ,  Quan Wang ,  Xiaodong Xia

IPC分类号： G06F9/46 ,  G06F9/50 ,  G06F17/00

CPC分类号： G06F9/5077 ,  G06F9/54

摘要： A method, apparatus, and computer instructions for improving performance and scalability of common information model object (CIMOM) by using a hardware management console (HMC) repository. The HMC repository includes storage of HMC objects, an HMC object model and a common interface (CIM Wrapper) for accessing to HMC objects. The HMC object model allows the user to store and retrieve the CIM objects and their associations efficiently. A CIM provider may access HMC objects through a common interface (CIM Wrapper), so that different repositories are allowed to be used without significant changes to the underlying server code (CIM provider). A CIM provider may also call the HMC repository directly for more efficient operations because the number of times conversions made between the CIM object and the repository object are greatly decreased.

摘要翻译： 一种通过使用硬件管理控制台（HMC）存储库来提高公共信息模型对象（CIMOM）的性能和可扩展性的方法，装置和计算机指令。 HMC存储库包括HMC对象的存储，HMC对象模型和用于访问HMC对象的公共接口（CIM Wrapper）。 HMC对象模型允许用户有效地存储和检索CIM对象及其关联。 CIM提供商可以通过公共接口（CIM Wrapper）访问HMC对象，以便允许使用不同的存储库，而不会对底层服务器代码（CIM提供程序）进行重大更改。 CIM提供商也可以直接调用HMC存储库来进行更有效的操作，因为在CIM对象和存储库对象之间进行转换的次数大大降低。