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公开(公告)号:US4920215A
公开(公告)日:1990-04-24
申请号:US133752
申请日:1987-12-16
IPC分类号: C12P19/44 , A23K20/195 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P3/00 , A61P31/04 , C07H17/04 , C12N1/20 , C12P19/60 , C12R1/01
CPC分类号: C07H17/04 , A23K20/195 , Y10S435/872 , Y10S435/886 , Y10S514/867
摘要: The antibiotic of the formula: ##STR1## wherein R is ##STR2## The antibiotic is useful for the treatment of swine dysentery and for promoting growth and/or increasing the efficiency of food utilization in poultry, swine and ruminants.
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公开(公告)号:US4992369A
公开(公告)日:1991-02-12
申请号:US366576
申请日:1989-06-15
申请人: Hiroshi Maeda , Junsuke Tone , John C. Ruddock , Kelvin S. Holdom
发明人: Hiroshi Maeda , Junsuke Tone , John C. Ruddock , Kelvin S. Holdom
IPC分类号: A23K20/195 , A61K38/00 , A61P31/04 , A61P33/02 , A61P43/00 , C07K1/20 , C07K1/22 , C07K9/00 , C07K14/195 , C07K14/41 , C12N1/20 , C12P21/02 , C12R1/045
CPC分类号: C12R1/045 , C07K9/008 , Y10S435/827
摘要: A new glycopeptide antibiotic UK-68,597 can be prepared by submerged aerobic propagation in aqueous nutrient media of Actinoplanes sp. ATCC 53533. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in poultry, swine and ruminants.
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公开(公告)号:US4954482A
公开(公告)日:1990-09-04
申请号:US384052
申请日:1989-07-20
申请人: Hiroshi Maeda , Junsuke Tone , John C. Ruddock , Kelvin S. Holdom
发明人: Hiroshi Maeda , Junsuke Tone , John C. Ruddock , Kelvin S. Holdom
IPC分类号: A23K20/195 , A61K38/00 , A61P31/04 , A61P33/02 , A61P43/00 , C07K1/20 , C07K1/22 , C07K9/00 , C07K14/195 , C07K14/41 , C12N1/20 , C12P21/02 , C12R1/045
CPC分类号: C12R1/045 , C07K9/008 , Y10S435/827
摘要: A new glycopeptide antibiotic UK-68,597 can be prepared by submerged aerobic propagation in aqueous nutrient media of Actinoplanes sp. ATCC 53533. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in poultry, swine and ruminants.
摘要翻译: 一种新的糖肽抗生素UK-68,597可以通过淹没有氧繁殖在肌动蛋白平板的水性营养培养基中制备。 抗生素及其阳离子盐对多种微生物具有活性,有效控制球虫病,肠炎,猪痢疾和败血症,以及有效促进家禽,猪的生长和/或提高饲料利用效率。 和反刍动物。
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公开(公告)号:US4746650A
公开(公告)日:1988-05-24
申请号:US747613
申请日:1985-06-21
申请人: Walter P. Cullen , Hiroshi Maeda , John C. Ruddock , Junsuke Tone
发明人: Walter P. Cullen , Hiroshi Maeda , John C. Ruddock , Junsuke Tone
IPC分类号: A23K20/195 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/00 , A61P31/04 , A61P33/02 , C07H17/04 , C07H19/01 , C12P17/18 , C12P19/44 , C12P19/60 , C12R1/03 , A61K31/71 , A23G3/00
CPC分类号: C07H19/01 , C12P19/44 , C12P19/60 , C12R1/03 , Y10S435/825
摘要: A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in swine and ruminants. Two minor components, wherein R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
摘要翻译: 一种新的酸性多环醚抗生素UK-58,852具有以下分子式:其中R和R1都是氢,并且可以通过在放线菌属的水性营养培养基中浸没需氧繁殖来制备。 抗生素及其阳离子盐对各种微生物有活性,有效控制球虫病,肠炎,猪痢疾和腹膜炎,以及有效促进生长和/或提高猪和反刍动物饲料利用效率 。 从发酵中也分离出两个次要组分,其中R为H且R 1为CH 3,并且其中R和R 1均为CH 3。
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公开(公告)号:US4707493A
公开(公告)日:1987-11-17
申请号:US931587
申请日:1986-11-17
IPC分类号: C07H19/01 , C12P19/44 , C12P19/60 , C07D309/10
CPC分类号: C07H19/01 , C12P19/445 , C12P19/60 , C12R1/55
摘要: Antibiotic 19-epi-dianemycin, process for its preparation by fermenting a new strain of Streptomyces hygroscopicus, and isolation from the fermentation broth; and its use as an anticoccidial agent and antibacterial agent against gram-positive bacteria.
摘要翻译: 抗生素19-epi-dianemycin,其制备方法是通过发酵新的吸水链霉菌菌株和从发酵液中分离; 并作为抗球虫剂和抗革兰氏阳性菌的抗菌剂使用。
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公开(公告)号:US5100785A
公开(公告)日:1992-03-31
申请号:US628798
申请日:1990-12-17
申请人: Walter P. Cullen , Hiroshi Maeda , John C. Ruddock , Junsuke Tone
发明人: Walter P. Cullen , Hiroshi Maeda , John C. Ruddock , Junsuke Tone
IPC分类号: A23K20/195 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/00 , A61P31/04 , A61P33/02 , C07H17/04 , C07H19/01 , C12P17/18 , C12P19/44 , C12P19/60 , C12R1/03
CPC分类号: C07H19/01 , C12P19/44 , C12P19/60 , C12R1/03 , Y10S435/825
摘要: A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization in swine and ruminants. Two minor components, wherein R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
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公开(公告)号:US4992423A
公开(公告)日:1991-02-12
申请号:US153187
申请日:1988-02-08
申请人: Walter P. Cullen , Hiroshi Maeda , John C. Ruddock , Junsuke Tone
发明人: Walter P. Cullen , Hiroshi Maeda , John C. Ruddock , Junsuke Tone
IPC分类号: A23K20/195 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/00 , A61P31/04 , A61P33/02 , C07H17/04 , C07H19/01 , C12P17/18 , C12P19/44 , C12P19/60 , C12R1/03
CPC分类号: C07H19/01 , C12P19/44 , C12P19/60 , C12R1/03 , Y10S435/825
摘要: A new acidic polycyclic ether antibiotic UK-58,852 has the formula: ##STR1## wherein R and R.sup.1 are both hydrogen, and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Actinomadura sp. ATCC 39697. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effective in promotion of growth and/or improving efficiency of feed utilization is swine and ruminants. Two minor components, where R is H and R.sup.1 is CH.sub.3 and wherein R and R.sup.1 are both CH.sub.3, have also been isolated from the fermentation.
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