公开(公告)号：US20050075709A1

公开(公告)日：2005-04-07

申请号：US10368153

申请日：2003-02-18

申请人： Kenneth Brennen ,  William Schindeldecker ,  Scott Brabec

发明人： Kenneth Brennen ,  William Schindeldecker ,  Scott Brabec

IPC分类号： A61N1/05

CPC分类号： A61N1/0565 ,  A61N1/056

摘要： An implantable biomedical electrode includes platinum particles electrochemically deposited upon, and sintered to a surface.

摘要翻译： 植入式生物医学电极包括电化学沉积在表面上并烧结在表面上的铂颗粒。

公开(公告)号：US20050049665A1

公开(公告)日：2005-03-03

申请号：US10648908

申请日：2003-08-27

申请人： Scott Brabec ,  Jordon Honeck ,  William Schindeldecker

发明人： Scott Brabec ,  Jordon Honeck ,  William Schindeldecker

IPC分类号： A61N1/05

CPC分类号： A61N1/0568 ,  A61N1/0573

摘要： An insulative housing formed about a distal end of a medical electrical lead body includes a cavity and a port; an ionically conductive medium fills the cavity and is in intimate contact with an electrode surface contained within the cavity. When a current is delivered to the electrode surface contained within the cavity, a first current density generated at the electrode surface is smaller than a second current density generated out from the port of the insulative housing; thus, the port forms a high impedance and low polarization tissue-stimulating electrode.

摘要翻译： 形成在医疗用电引线体的前端的绝缘壳体具有空腔和端口; 离子导电介质填充空腔并与包含在空腔内的电极表面紧密接触。 当电流被传送到包含在空腔内的电极表面时，在电极表面处产生的第一电流密度小于从绝缘壳体的端口产生的第二电流密度; 因此，端口形成高阻抗和低极化组织刺激电极。

公开(公告)号：US20060217777A1

公开(公告)日：2006-09-28

申请号：US11085843

申请日：2005-03-22

申请人： James Strom ,  Scott Brabec ,  John Nicholson ,  Michael Fletcher ,  Thomas Adamski ,  Christopher Stancer

发明人： James Strom ,  Scott Brabec ,  John Nicholson ,  Michael Fletcher ,  Thomas Adamski ,  Christopher Stancer

IPC分类号： A61N1/375

CPC分类号： A61N1/375 ,  A61N1/0504 ,  A61N1/3756

摘要： The present invention provides a subcutaneous (or submuscular) single or multiple-electrode array that provides various embodiments of a compliant surround shroud coupled to a peripheral portion of an implantable medical device (IMD). The shroud incorporates a plurality of substantially planar electrodes mechanically coupled within recessed portions of the shroud. These electrodes electrically couple to IMD circuitry to monitor cardiac activity of a subject. Temporal recordings of the detected cardiac activity are referred to herein as an extra-cardiac electrogram (EC-EGM). The recordings can be stored upon computer readable media within an IMD at various resolution (e.g., continuous beat-by-beat, periodic, triggered, mean value, average value, etc.). Real time or stored EC-EGM signals can be provided to remote equipment via telemetry. For example, when telemetry, or programming, head of an IMD programming apparatus is positioned within range of an IMD the programmer receives some or all of the EC-EGM signals.

摘要翻译： 本发明提供皮下（或肌内）单电极阵列或多电极阵列，其提供耦合到可植入医疗装置（IMD）的周边部分的顺应性环绕护罩的各种实施例。 护罩包括多个基本上平面的电极，机械耦合在护罩的凹陷部分内。 这些电极电耦合到IMD电路以监测受试者的心脏活动。 检测到的心脏活动的时间记录在本文中称为心外电图（EC-EGM）。 记录可以以各种分辨率（例如，连拍，逐周期，触发，平均值，平均值等）存储在IMD内的计算机可读介质上。 可以通过遥测提供实时或存储的EC-EGM信号到远程设备。 例如，当遥测或编程时，IMD编程设备的头部位于IMD的范围内，程序员接收部分或全部EC-EGM信号。

公开(公告)号：US20100114271A1

公开(公告)日：2010-05-06

申请号：US12262306

申请日：2008-10-31

申请人： John L. Sommer ,  Scott Brabec

发明人： John L. Sommer ,  Scott Brabec

IPC分类号： H01B3/44 ,  A61N1/04

CPC分类号： A61B5/0031 ,  A61B5/0006 ,  A61B2562/222 ,  A61N1/05 ,  A61N1/086

摘要： A lead for a medical device includes an elongate filar core member having an axis, which is operable for transmitting a lead signal. Furthermore, the lead includes an insulating layer disposed directly on the elongate filar core member and that extends along the axis. The lead also includes an electrically conductive layer disposed directly on the insulating layer and that extends along the axis.

摘要翻译： 用于医疗装置的引线包括具有轴的细长丝状芯构件，其可操作用于传送引导信号。 此外，引线包括绝缘层，其直接设置在细长丝状芯部件上并且沿轴线延伸。 引线还包括直接设置在绝缘层上并沿轴线延伸的导电层。

公开(公告)号：US20060167536A1

公开(公告)日：2006-07-27

申请号：US11042649

申请日：2005-01-25

申请人： Lea Nygren ,  James Coles ,  Scott Brabec ,  Randy Rose

发明人： Lea Nygren ,  James Coles ,  Scott Brabec ,  Randy Rose

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  C23C28/32 ,  Y10T29/49204

摘要： A method for fabricating an implantable medical electrode includes roughening the electrode substrate, applying an adhesion layer, and depositing a valve metal oxide coating over the adhesion layer under conditions optimized to minimize electrode impedance and post-pulse polarization. The electrode substrate may be a variety of electrode metals or alloys including titanium, platinum, platinum-iridium, or niobium. The adhesion layer may be formed of titanium or zirconium. The valve metal oxide coating is a ruthenium oxide coating sputtered onto the adhesion layer under controlled target power, sputtering pressure, and sputter gas ratio setting optimized to minimize electrode impedance and post-pulse polarization.

摘要翻译： 一种用于制造可植入医疗电极的方法包括使电极基板粗糙化，施加粘合层，以及在优化以最小化电极阻抗和脉冲后极化的条件下，在粘附层上沉积阀金属氧化物涂层。 电极基板可以是各种电极金属或包括钛，铂，铂 - 铱或铌的合金。 粘合层可以由钛或锆形成。 阀金属氧化物涂层是在受控目标功率，溅射压力和溅射气体比设置下溅射到粘附层上的氧化钌涂层，其被优化以最小化电极阻抗和后脉冲极化。

公开(公告)号：US20060217778A1

公开(公告)日：2006-09-28

申请号：US11086837

申请日：2005-03-22

申请人： James Strom ,  Scott Brabec ,  John Nicholson ,  Michael Fletcher ,  Thomas Adamski ,  Christopher Stancer

发明人： James Strom ,  Scott Brabec ,  John Nicholson ,  Michael Fletcher ,  Thomas Adamski ,  Christopher Stancer

IPC分类号： A61N1/375

CPC分类号： A61N1/375 ,  A61N1/0504 ,  A61N1/3756

摘要： The present invention provides a subcutaneous (or submuscular) single or multiple-electrode array including various embodiments of a surround shroud coupled to a peripheral portion of an implantable medical device (IMD). The shroud incorporates a plurality of substantially planar electrodes mechanically coupled within recessed portions of the shroud. These electrodes electrically couple to IMD circuitry to monitor cardiac activity of a subject. Temporal recordings of the detected cardiac activity are referred to herein as an extra-cardiac electrogram (EC-EGM). The recordings can be stored upon computer readable media within an IMD at various resolution (e.g., continuous beat-by-beat, periodic, triggered, mean value, average value, etc.). Real time or stored EC-EGM signals can be provided to remote equipment via telemetry. For example, when telemetry, or programming, head of an IMD programming apparatus is positioned within range of an IMD the programmer receives some or all of the EC-EGM signals.

摘要翻译： 本发明提供包括耦合到可植入医疗装置（IMD）的周边部分的环绕护罩的各种实施例的皮下（或肌肉下）单电极阵列或多电极阵列。 护罩包括多个基本上平面的电极，机械耦合在护罩的凹陷部分内。 这些电极电耦合到IMD电路以监测受试者的心脏活动。 检测到的心脏活动的时间记录在本文中称为心外电图（EC-EGM）。 记录可以以各种分辨率（例如，连拍，逐周期，触发，平均值，平均值等）存储在IMD内的计算机可读介质上。 可以通过遥测提供实时或存储的EC-EGM信号到远程设备。 例如，当遥测或编程时，IMD编程设备的头部位于IMD的范围内，程序员接收部分或全部EC-EGM信号。

公开(公告)号：US20050288761A1

公开(公告)日：2005-12-29

申请号：US10876003

申请日：2004-06-24

申请人： Scott Brabec ,  Douglas Hine

发明人： Scott Brabec ,  Douglas Hine

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N2001/0585

摘要： A pacing lead includes a first pacing cathode coupled to a first conductor, a second pacing cathode coupled to a second conductor, and a flexible anode coupled to a third conductor. The flexible anode has a length less than approximately 10 millimeters and is spaced apart from and proximal to the first pacing cathode and spaced apart from and distal to the second pacing cathode. The spacing between the anode and the first pacing cathode is approximately equal to the spacing between the anode and the second pacing cathode.

摘要翻译： 起搏引线包括耦合到第一导体的第一起搏阴极，耦合到第二导体的第二起搏阴极和耦合到第三导体的柔性阳极。 柔性阳极具有小于约10毫米的长度，并且与第一起搏阴极间隔开并靠近第一起搏阴极并与第二起搏阴极间隔开并远离第二起搏阴极。 阳极和第一起搏阴极之间的间隔大致等于阳极和第二起搏阴极之间的间隔。

公开(公告)号：US20050203604A1

公开(公告)日：2005-09-15

申请号：US11038731

申请日：2005-01-20

申请人： Scott Brabec ,  Kenneth Gardeski

发明人： Scott Brabec ,  Kenneth Gardeski

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/0565 ,  Y10S977/905 ,  Y10S977/925 ,  Y10S977/931

摘要： The present invention relates generally to medical devices; in particular and without limitation, to unique electrodes and/or electrical lead assemblies for stimulating cardiac tissue, muscle tissue, neurological tissue, brain tissue and/or organ tissue; to electrophysiology mapping and ablation catheters for monitoring and selectively altering physiologic conduction pathways; and, wherein said electrodes, lead assemblies and catheters optionally include fluid irrigation conduit(s) for providing therapeutic and/or performance enhancing materials to adjacent biological tissue, and wherein each said device is coupled to or incorporates nanostructure or materials therein. The present invention also provides methods for fabricating, deploying, and operating such medical devices.

摘要翻译： 本发明一般涉及医疗器械; 特别是但不限于用于刺激心脏组织，肌肉组织，神经组织，脑组织和/或器官组织的独特电极和/或电引线组件; 用于电生理测绘和消融导管，用于监测和选择性地改变生理传导途径; 并且其中所述电极，引线组件和导管可选地包括用于向相邻生物组织提供治疗和/或性能增强材料的流体冲洗导管，并且其中每个所述装置与其中的纳米结构或材料耦合或结合。 本发明还提供了制造，部署和操作这种医疗装置的方法。