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公开(公告)号：US20050282261A1
公开(公告)日：2005-12-22
申请号：US11156003
申请日：2005-06-17
申请人： Kerstin Sauter , Albrecht Weiss , Karl-Heinz Maurer , Stefan Evers , Nina Hoven , Susanne Wieland , Regina Stehr , Cornelius Bessler
发明人： Kerstin Sauter , Albrecht Weiss , Karl-Heinz Maurer , Stefan Evers , Nina Hoven , Susanne Wieland , Regina Stehr , Cornelius Bessler
CPC分类号： C12N9/0006 , A61K8/66 , A61Q5/02 , A61Q5/10 , A61Q11/02 , C12Y101/03017
摘要： The invention relates to novel choline oxidases, methods for obtaining the same, bodycare products, haircare products, shampoos, oral, dental and dental prosthesis care products, cosmetics, washing products, cleaning products, rinsing products, hand soaps, washing-up detergents and dishwasher detergents comprising novel choline oxidases and uses of the novel choline oxidases.
摘要翻译： 本发明涉及新型胆碱氧化酶，其获得方法，身体护理产品，护发产品，洗发剂，口腔，牙科和牙科假体护理产品，化妆品，洗涤产品，清洁产品，漂洗产品，手肥皂，洗涤洗涤剂和 洗碗机洗涤剂包含新型胆碱氧化酶和新型胆碱氧化酶的用途。
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2.发明申请公开(公告)号：US20090156454A1
公开(公告)日：2009-06-18
申请号：US12254350
申请日：2008-10-20
申请人： Peter Schmiedel , Petra Padurschel , Heribert Kaiser , Anette Nordskog , Wolfgang von Rybinski , Regina Stehr , Karl-Heinz Maurer , Cornelius Bessler , Soeren Hoelsken , Rolf Tenhaef
发明人： Peter Schmiedel , Petra Padurschel , Heribert Kaiser , Anette Nordskog , Wolfgang von Rybinski , Regina Stehr , Karl-Heinz Maurer , Cornelius Bessler , Soeren Hoelsken , Rolf Tenhaef
CPC分类号： C11D3/505 , C11D3/38672 , C11D3/3935 , C11D3/42 , C11D17/0034 , C11D17/0039
摘要： Granulates for washing- or cleaning agents, containing (a) a sensitive washing- or cleaning agent component, (b) an adsorbent carrier material, (c) a binder that is different from (b), and (d) optional additional substances that are different from (b) and (c). The granulates display a disintegration index of at least 50 percent after 24 hours. These granulates are particularly suited for use in liquid- or gel-forming aqueous washing- or cleaning agents. Also, a procedure for the manufacture of such granulates, in regards to washing- or cleaning agents.
摘要翻译： 含有（a）敏感的洗涤剂或清洁剂组分，（b）吸附剂载体材料，（c）不同于（b）的粘合剂和（d）任选的附加物质的洗涤剂或清洁剂的颗粒剂， 与（b）和（c）不同。 颗粒在24小时后显示至少50％的崩解指数。 这些颗粒特别适用于液体或凝胶形成的水性洗涤剂或清洁剂。 此外，关于洗涤剂或清洁剂的制造这种颗粒的方法。
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公开(公告)号：US07510859B2
公开(公告)日：2009-03-31
申请号：US11156062
申请日：2005-06-17
IPC分类号： C12N9/16 , C12N15/55 , C12N15/74 , C12N15/75 , A61Q5/10 , A61Q11/02 , C11D3/386 , C11D3/395 , C12P7/02 , C12N9/54 , C12N15/70 , A61K8/38 , A61Q5/08
CPC分类号： C11D3/38636 , C12N9/54
摘要： The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136, 140, 147, 150, 154, 155, 160, 161, 171, 179, 180, 181, 194, 205, 208, 213, 216, 217, 238, 239, 251, 253, 257, and/or 261. The invention further relates to methods for production of said novel perhydrolases, products comprising said novel perhydrolases, particularly bodycare, haircare, shampoo, hair-dyeing, hair-bleaching, oral-care, dental-dare, dental-prosthesis-care, cosmetic, therapeutic (textile) washing, cleaning, rinsing, handwash, washing-up and dish-washing products, and corresponding applications of said novel perhydrolases.
摘要翻译： 本发明涉及新的过水解酶，其通过在11,15,21,38,50,54,58,77,83,89,93,96,107,117， 135,136,140,147,150,154,155,160,161,171,179,180,181,194,205,208,213,216,217,238,239,251,253,257和/或其中的/ 本发明还涉及生产所述新型过水解酶的方法，包含所述新型过水解酶的产品，特别是身体护理，护发，洗发剂，染发剂，脱毛剂，口腔护理剂，牙科用品，牙科假体护理 ，化妆品，治疗（纺织品）洗涤，清洁，漂洗，洗手和洗碗产品，以及所述新型过水解酶的相应应用。
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4.发明授权Alpha-amylase variants stabilized against dimerization and/or multimerization, method for the production thereof, and detergents and cleansers containing these alpha-amylase variants 有权稳定抗二聚和/或多聚化的α-淀粉酶变体，其生产方法，以及含有这些α-淀粉酶变体的洗涤剂和清洁剂公开(公告)号：US08785365B2
公开(公告)日：2014-07-22
申请号：US11692691
申请日：2007-03-28
CPC分类号： C12N9/2417 , C11D3/38681
摘要： The present invention relates to α-amylase variants that are stabilized to dimerization and/or multimerization, in particular at elevated temperatures or high pH, by point mutagenesis of positively polarized or charged or neutral surface amino acids to give more negatively polarized or charged amino acids. The invention further relates to methods of increasing the stability of an α-amylase to dimerization and/or multimerization brought about by electrostatic interactions whereby at least one amino acid residue on the surface of the starting molecule, which makes a neutral or positively polar or charged contribution to the electrostatic potential of said molecule, is replaced with a more negatively polar or negatively charged amino acid residue. The α-amylase variants obtained thereby exhibit better stability to influences of the solvent, increased processivity, and are suited for numerous industrial areas of use, in particular as active ingredients in detergents and cleansers.
摘要翻译： 本发明涉及通过正极化或带电荷或中性表面氨基酸的点诱变稳定至二聚化和/或多聚化的α-淀粉酶变体，特别是在升高的温度或高pH下，以产生更多的负极化或带电荷的氨基酸 。 本发明还涉及增加α-淀粉酶对由静电相互作用引起的二聚化和/或多聚化的稳定性的方法，其中起始分子表面上至少有一个氨基酸残基，其形成中性或正极性或带电 对所述分子的静电电位的贡献被更负极性或带负电荷的氨基酸残基取代。 由此获得的α-淀粉酶变体对溶剂的影响表现出更好的稳定性，增加的持续性，并且适用于许多工业使用领域，特别是作为洗涤剂和清洁剂中的活性成分。
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公开(公告)号：US20050281773A1
公开(公告)日：2005-12-22
申请号：US11156062
申请日：2005-06-17
CPC分类号： C11D3/38636 , C12N9/54
摘要： The invention relates to novel perhydrolases, derived from the protease Carlsberg by amino acid exchange in positions 11, 15, 21, 38, 50, 54, 58, 77, 83, 89, 93, 96, 107, 117, 120, 134, 135, 136, 140, 147, 150, 154, 155, 160, 161, 171, 179, 180, 181, 194, 205, 208, 213, 216, 217, 238, 239, 251, 253, 257, and/or 261. The invention further relates to methods for production of said novel perhydrolases, products comprising said novel perhydrolases, particularly bodycare, haircare, shampoo, hair-dyeing, hair-bleaching, oral-care, dental-dare, dental-prosthesis-care, cosmetic, therapeutic (textile) washing, cleaning, rinsing, handwash, washing-up and dish-washing products, and corresponding applications of said novel perhydrolases.
摘要翻译： 本发明涉及新的过水解酶，其通过在11,15,21,38,50,54,58,77,83,89,93,96,107,117， 135,136,140,147,150,154,155,160,161,171,179,180,181,194,205,208,213,216,217,238,239,251,253,257和/或其中的/ 本发明还涉及生产所述新型过水解酶的方法，包含所述新型过水解酶的产品，特别是身体护理，护发，洗发剂，染发剂，脱毛剂，口腔护理剂，牙科用品，牙科假体护理 ，化妆品，治疗（纺织品）洗涤，清洁，漂洗，洗手和洗碗产品，以及所述新型过水解酶的相应应用。
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公开(公告)号：US20100234267A1
公开(公告)日：2010-09-16
申请号：US12685215
申请日：2010-01-11
申请人： Petra Siegert , Susanne Wieland , Karl-Heinz Maurer , Cornelius Bessler , Doris Ribitsch , Sonja Heumann , Georg Gübitz , Wolfgang Karl , Peter Remler , Helmut Schwab , Gabriele Berg , Jochen Gerlach
发明人： Petra Siegert , Susanne Wieland , Karl-Heinz Maurer , Cornelius Bessler , Doris Ribitsch , Sonja Heumann , Georg Gübitz , Wolfgang Karl , Peter Remler , Helmut Schwab , Gabriele Berg , Jochen Gerlach
摘要： The present invention relates to agent compositions, in particular washing and cleaning agents, that contain a protease from a bacterial strain of the species Stenotrophomonas maltophilia, and to said proteases themselves. The invention further relates to cleaning methods in which said agents are used, and to uses of said agents. The invention further relates to the manufacture and use of these proteases themselves.
摘要翻译： 本发明涉及含有来自嗜麦芽寡养单胞菌属细菌菌株的蛋白酶和所述蛋白酶本身的药剂组合物，特别是洗涤和清洁剂。 本发明还涉及其中使用所述试剂的清洁方法以及所述试剂的用途。 本发明还涉及这些蛋白酶本身的制造和使用。
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7.发明申请Novel Alkaline Protease from Bacillus Gibsonii and Washing and Cleaning Agents containing said Novel Alkaline Protease 审中-公开来自芽孢杆菌的新型碱性蛋白酶和含有所述新型碱性蛋白酶的洗涤和清洁剂公开(公告)号：US20090275493A1
公开(公告)日：2009-11-05
申请号：US12502459
申请日：2009-07-14
申请人： Petra Siegert , Susanne Wieland , Julia Engelskirchen , Marion Merkel , Karl-Heinz Maurer , Cornelius Bessler
发明人： Petra Siegert , Susanne Wieland , Julia Engelskirchen , Marion Merkel , Karl-Heinz Maurer , Cornelius Bessler
摘要： A novel subtilisin-type alkaline protease from Bacillus gibsonii and to sufficiently related proteins and the derivatives thereof. Also, washing and cleaning agents comprising the novel subtilisin-type alkaline protease, sufficiently related proteins and the derivatives thereof, corresponding washing and cleaning methods and their use in washing and cleaning agents, and other possible technical uses.
摘要翻译： 来自芽孢杆菌的新型枯草杆菌蛋白酶型碱性蛋白酶和足够相关的蛋白质及其衍生物。 此外，包含新的枯草杆菌蛋白酶型碱性蛋白酶，足够相关的蛋白质及其衍生物的洗涤和清洁剂，相应的洗涤和清洁方法及其在洗涤和清洁剂中的用途以及其它可能的技术用途。
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8.发明授权Alpha-amylase variants having an elevated solvent stability, method for the production thereof and detergents and cleansers containing these alpha-amylase variants 有权具有提高的溶剂稳定性的α-淀粉酶变体，其制备方法和含有这些α-淀粉酶变体的洗涤剂和清洁剂公开(公告)号：US08080401B2
公开(公告)日：2011-12-20
申请号：US11692504
申请日：2007-03-28
CPC分类号： C11D3/38681 , C12N9/2417
摘要： The present invention relates to α-amylase variants that are stabilized to solvent-exerted hydrolysis, in particular at elevated temperatures or high pH, by point mutagenesis of asparagine (N) or glutamine (Q) residues located on the surface of the molecule to give other amino acid residues. The invention further relates to methods of increasing the stability of an α-amylase to solvent-exerted hydrolysis, in particular at elevated temperatures or high pH, whereby at least one asparagine (N) or glutamine (Q) residue on the surface of the molecule is replaced with a different amino acid residue. The α-amylase variants obtained thereby exhibit better stability to influences of the solvent, increased processivity, and are suited for numerous industrial areas of use, in particular as active ingredients in detergents and cleansers.
摘要翻译： 本发明涉及通过位于分子表面上的天冬酰胺（N）或谷氨酰胺（Q）残基的点诱变而稳定化为溶剂施加水解的α-淀粉酶变体，特别是在升高的温度或高pH下，得到 其他氨基酸残基。 本发明还涉及增加α-淀粉酶对溶剂发生水解的稳定性的方法，特别是在升高的温度或高pH下，其中分子表面上至少有一个天冬酰胺（N）或谷氨酰胺（Q）残基 被不同的氨基酸残基取代。 由此获得的α-淀粉酶变体对溶剂的影响表现出更好的稳定性，增加的持续性，并且适用于许多工业使用领域，特别是作为洗涤剂和清洁剂中的活性成分。
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9.发明申请SUBTILISIN FROM BACILLUS PUMILUS AND DETERGENT AND CLEANING AGENTS CONTAINING SAID NOVEL SUBTILISIN 审中-公开来自BACILLUS PUMILUS和洗涤剂和含有新型分散素的清洁剂的分散体公开(公告)号：US20090170745A1
公开(公告)日：2009-07-02
申请号：US12268702
申请日：2008-11-11
IPC分类号： C11D7/42 , C12N15/57 , C12N15/75 , C12N9/54 , C12S11/00 , C12S9/00 , C12N15/77 , C12N15/70 , C12N1/21
CPC分类号： C12N9/54 , A61K38/00 , C11D3/386 , C12Y304/21062 , Y02A50/473
摘要： A novel subtilisin-type alkaline protease from Bacillus pumilus and sufficiently related proteins and derivatives thereof. Also washing and cleaning agents comprising the novel subtilisin-type alkaline protease, sufficiently related proteins and derivatives thereof, corresponding washing and cleaning methods, and washing and cleaning agents and other possible technical uses.
摘要翻译： 来自短小芽孢杆菌的新型枯草杆菌蛋白酶型碱性蛋白酶和足够相关的蛋白质及其衍生物。 还有洗涤和清洁剂，其包含新的枯草杆菌蛋白酶型碱性蛋白酶，足够相关的蛋白质及其衍生物，相应的洗涤和清洁方法，以及洗涤和清洁剂以及其它可能的技术用途。
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10.发明申请公开(公告)号：US20070190605A1
公开(公告)日：2007-08-16
申请号：US11616319
申请日：2006-12-27
申请人： Cornelius Bessler , Jorg Feesche , Stefan Evers , Karl-Heinz Maurer , Armin Ehrenreich , Birgit Veith , Heiko Liesegang , Anke Henne , Christina Herzberg , Gerhard Gottschalk
发明人： Cornelius Bessler , Jorg Feesche , Stefan Evers , Karl-Heinz Maurer , Armin Ehrenreich , Birgit Veith , Heiko Liesegang , Anke Henne , Christina Herzberg , Gerhard Gottschalk
IPC分类号： C07H21/04 , C12P21/06 , C12P7/40 , C12N9/02 , C12N9/16 , C12N9/32 , C12N9/42 , C12N9/50 , C12N9/64 , C12N15/74 , C12N1/21
CPC分类号： C12N15/52 , C12N9/0006 , C12N9/0008 , C12N9/001 , C12N9/0016 , C12N9/1025 , C12N9/1029 , C12N9/1096 , C12N9/1217 , C12N9/16 , C12N9/78 , C12N9/80 , C12N9/84 , C12N9/88 , C12N9/93 , C12N15/75 , C12P7/16 , C12P7/40 , C12P7/42 , C12P7/52 , C12P13/001 , C12Y101/01 , C12Y101/01035 , C12Y101/01157 , C12Y102/04002 , C12Y103/99 , C12Y203/01019 , C12Y206/01042 , C12Y207/02007 , C12Y305/01001 , C12Y305/01011 , C12Y401/01018 , C12Y401/01019 , C12Y402/01017 , C12Y402/01055 , C12Y602/01 , C12Y602/01001 , Y02E50/10 , Y02P20/52
摘要： The present invention relates to 25 hitherto undescribed genes of B. licheniformis and gene products derived therefrom and all sufficiently homologous nucleic acids and proteins thereof. They occur in five different metabolic pathways for the formation of odorous substances. The metabolic pathways in question are for the synthesis of: 1) isovalerian acid (as part of the catabolism of leucine), 2) 2-methylbutyric acid and/or isobutyric acid (as part of the catabolism of valine and/or isoleucine), 3) butanol and/or butyric acid (as part of the metabolism of butyric acid), 4) propyl acid (as part of the metabolism of propionate) and/or 5) cadaverine and/or putrescine (as parts of the catabolism of lysine and/or arginine). The identification of these genes allows biotechnological production methods to be developed that are improved to the extent that, to assist these nucleic acids, the formation of the odorous substances synthesized via these metabolic pathways can be reduced by deactivating the corresponding genes in the micro-organism used for the biotechnological production. In addition, these gene products are thus available for preparing reactions or for methods according to their respective biochemical properties.
摘要翻译： 本发明涉及地衣芽孢杆菌的25个迄今未描述的基因及其衍生的基因产物及其全部充分同源的核酸及其蛋白质。 它们发生在五种不同的代谢途径中，用于形成气味物质。 所讨论的代谢途径是用于合成：1）异戊酸（作为亮氨酸分解代谢的一部分），2）2-甲基丁酸和/或异丁酸（作为缬氨酸和/或异亮氨酸分解代谢的一部分） 3）丁醇和/或丁酸（作为丁酸代谢的一部分），4）丙酸（作为丙酸代谢的一部分）和/或5）尸胺和/或腐胺（作为赖氨酸分解代谢的一部分） 和/或精氨酸）。 这些基因的鉴定允许开发生物技术生产方法，其被改进到对于辅助这些核酸的程度，可以通过使微生物中相应的基因失活来减少通过这些代谢途径合成的恶臭物质的形成 用于生物技术生产。 此外，这些基因产物因此可用于制备反应或根据其各自生物化学性质的方法。
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