Abstract:
The present disclosure provides non-naturally occurring miR-196a-2 miRNAs and non-naturally occurring miR-204 miRNAs. The non-naturally occurring miRNAs of the disclosure have mature strand sequences distinct from their endogenous counterparts. The disclosure also provides methods of selecting mature strand sequences that function optimally in non-naturally occurring miR-196a-2 miRNAs. The methods and compositions of the disclosure may be used to mediate gene silencing via the RNAi pathway.
Abstract:
A centrifugal assembly is provided that can be used in common laboratory fixed angle or swinging bucket centrifuges for the separation of material, such as parasitic ova, based on particle density. The centrifugal assembly allows the fluid level to be gently adjusted to form a meniscus without disruption of the buoyant matter, such as ova. The centrifugal assembly also enables a user to easily and hygienically collect and transfer a measured amount of a sample, such as fecal material, and to break apart and mix the sample with a floatation fluid contained in a centrifuge tube.
Abstract:
A safety barrier with an integrated alarm comprising a plurality of posts for supporting fencing material, each post having an inner portion, an outer portion, an upper portion and a lower portion, wherein the lower portion of said post has embedded therein an alarm contact; a plurality of base supports for supporting posts, each base having an interior portion, an exterior portion, a top portion and a bottom portion, wherein the bottom of the interior portion of each base has an alarm contact embedded therein at the end proximate to the base support which corresponds to the alarm contact embedded in the lower portion of each post. The exterior portion of each base has an extension continuing downward from the bottom portion of each base for mounting in a ground surface or sleeve. The top portion of the base support contains an aperture having a diameter greater than the post. The bottom portion of the base is greater in diameter than the top portion thereof. Connecting alarm contacts embedded in the lower portion of the post and the bottom of the interior portion of the base closes the circuit between a transmitter and alarm contacts embedded in the lower portion of the post and the bottom of the interior portion of the base, which prevents the sound emitting device from emitting sound. Disconnecting alarm contacts embedded in the lower portion of the post and the bottom of the interior portion of the base opens a circuit, which causes a transmitter to send a signal to a receiver to trigger a sound emitting device to emit sound.
Abstract:
A computerized method and system for implementing such method, the method comprising establishing a card payment instrument account for an approved customer and an investment account for the benefit of the approved customer. A rebate is calculated periodically based on credit card usage and the rebate is applied to fund the investment account periodically. The rebate is the only funding of the investment account accomplished through the card payment instrument account.
Abstract:
A method and apparatus is provided for reformatting or interleaving a WDM signal that includes a plurality of optical channels having a first bandwidth and a first channel spacing. The method begins by receiving the WDM signal and dividing it into first and second subsets of optical channels each having a second channel spacing. Next, the first subset of optical channels are divided into third and fourth subsets of optical channels each having a third channel spacing. In addition, the second subset of optical channels is divided into fifth and sixth subsets of optical channels each having a fourth channel spacing. The third and fifth subsets of optical channels are combined to generate a first output WDM signal, while the fourth and sixth subsets of optical channels are combined to generate a second output WDM signal.
Abstract:
The abstract is amended to read, “An inventive method and apparatus is provided by a bidirectional optical 1×2 device formed by a cascade of three optical 2×2 devices. Each 2×2 device is bidirectional where optical signals propagate through the 2×2 device in the forward and backward directions simultaneously. The demultiplexing and multiplexing occur simultaneously to thereby perform bidirectional 1×2 optical demultiplexing and 2×1 optical multiplexing in the 1×2 device.”
Abstract:
An emergency vehicle alert system includes a traffic control device having a transceiver. The transceiver is configured to receive a first signal and to transmit a second signal. A receiver is configured to receive the second signal from the transceiver and to initiate an alert upon receiving the second signal from the transceiver. The first signal is transmitted to the transceiver from an emergency vehicle and causes the traffic control device to transition from a first configuration to a second configuration. The transceiver transmits the second signal in response to the transceiver receiving the first signal.
Abstract:
A computerized method and system for implementing such method, the method comprising establishing a card payment instrument account for an approved customer and an investment account for the benefit of the approved customer. A rebate is calculated periodically based on credit card usage and the rebate is applied to fund the investment account periodically. The rebate is the only funding of the investment account accomplished through the card payment instrument account.
Abstract:
A safety barrier with an integrated alarm has a plurality of posts for supporting fencing material. Each post having an inner, portion, an outer portion, an upper portion and a lower portion. The lower portion of each post has embedded therein an alarm contact. A plurality of base supports are used for supporting the posts. Each base support has an interior portion, an exterior portion, a top portion and a bottom portion. The bottom of the interior portion of each base support has an alarm contact embedded therein at the end proximate to the base support which corresponds to the alarm contact embedded in the lower portion of each post.
Abstract:
A hinge and support system for supporting cargo in a freight compartment is provided. The system includes a hinge member, associated with a deck panel, which has at least one flexible projection. The hinge member mates with a support member having a pocket for which the hinge member's flexible projections can be snapped into and retained within so as to allow pivotal movement of the hinge member with respect to the support member. The hinge member is also movably supported by the deck panel so that the hinge member can move relative to the deck panel when the deck panel is deployed. The support member includes one ledge which engages the deck panel when deployed and a second ledge which engages the panel when stowed upright so as to substantially isolate the hinge member from the weight of the deck panel and items placed on it. The hinge structure can be utilized in other contexts.