公开(公告)号：US20060128828A1

公开(公告)日：2006-06-15

申请号：US10546596

申请日：2005-01-14

申请人： Koichi Sato ,  Ryuji Higashi ,  Masayuki Ikegami ,  Keiichiro Tsubaki ,  Ikuo Nakazawa ,  Sakae Suda ,  Keiko Yamagishi ,  Takeshi Okada ,  Kohei Watanabe

发明人： Koichi Sato ,  Ryuji Higashi ,  Masayuki Ikegami ,  Keiichiro Tsubaki ,  Ikuo Nakazawa ,  Sakae Suda ,  Keiko Yamagishi ,  Takeshi Okada ,  Kohei Watanabe

IPC分类号： C03C17/00 ,  C08L29/04

CPC分类号： C09D11/30 ,  C08F297/00 ,  C08L53/00 ,  C09D11/54

摘要： Disclosed herein is an amphiphilic block copolymer having an ionic functional group, wherein the ratio (N10/N5) of a rotational viscosity (N10) of a 10% by mass solution of the copolymer in purified water to a rotational viscosity (N5) of a 5% by mass solution of the copolymer in purified water is 2.5 or lower.

摘要翻译： 本文公开了具有离子官能团的两亲性嵌段共聚物，其中，纯化水中共聚物的10质量％溶液的旋转粘度（N10）与旋转粘度（N10）之比（N10 / N5） 共聚物在纯化水中的5质量％溶液为2.5以下。

公开(公告)号：US07601790B2

公开(公告)日：2009-10-13

申请号：US10546596

申请日：2005-01-14

申请人： Koichi Sato ,  Ryuji Higashi ,  Masayuki Ikegami ,  Keiichiro Tsubaki ,  Ikuo Nakazawa ,  Sakae Suda ,  Keiko Yamagishi ,  Takeshi Okada ,  Kohei Watanabe

发明人： Koichi Sato ,  Ryuji Higashi ,  Masayuki Ikegami ,  Keiichiro Tsubaki ,  Ikuo Nakazawa ,  Sakae Suda ,  Keiko Yamagishi ,  Takeshi Okada ,  Kohei Watanabe

IPC分类号： C08F12/24 ,  C08F16/12

CPC分类号： C09D11/30 ,  C08F297/00 ,  C08L53/00 ,  C09D11/54

摘要： An amphiphilic block copolymer having an ionic functional group, wherein the ratio (N10/N5) of a rotational viscosity (N10) of a 10% by mass solution of the copolymer in purified water to a rotational viscosity (N5) of a 5% by mass solution of the copolymer in purified water is 2.5 or lower.

摘要翻译： 具有离子性官能团的两亲嵌段共聚物，其中，所述共聚物在纯水中的10质量％溶液的旋转粘度（N10）与旋转粘度（N5）的摩尔比（N5）的比（N10 / N5）为5％ 共聚物在纯化水中的质量溶液为2.5以下。

公开(公告)号：US07553884B2

公开(公告)日：2009-06-30

申请号：US11220179

申请日：2005-09-06

申请人： Kohei Watanabe ,  Takeshi Okada

发明人： Kohei Watanabe ,  Takeshi Okada

IPC分类号： C09D11/00

CPC分类号： C09D11/40

摘要： Disclosed herein is an ink set for use in ink-jet recording, which comprises at least 2 ink compositions the solid content concentrations of which are different by more than 2% by mass. The said at least 2 ink compositions each comprise an aqueous medium, a pigment and a dispersant for dispersing the pigment, and the dispersant is a block copolymer having an A segment that is a hydrophobic segment, a B segment that is an oxyethylene-structure-containing nonionic hydrophilic segment, and a C segment that is an ionic hydrophilic segment. The ratio of the number of unit structures of the A segment to the number of oxyethylene structures contained in the B segment (the number of unit structures of the A segment/the number of oxyethylene structures contained in the B segment) of the block copolymer contained in each of said at least 2 ink compositions is higher in the block copolymer contained in the ink composition having a relatively high solid content concentration than in the block copolymer contained in the ink composition having a relatively low solid content concentration.

摘要翻译： 本文公开了一种用于喷墨记录的油墨组，其包含至少2种固体含量浓度超过2质量％的油墨组合物。 所述至少2种油墨组合物各自包含水性介质，颜料和用于分散颜料的分散剂，并且分散剂是具有作为疏水链段的A链段的嵌段共聚物，作为氧化乙烯结构的B链段， 含有非离子亲水链段，和C段是离子性亲水链段。 嵌段共聚物中A链段的单元结构数与B链段中包含的氧化乙烯结构数（A链段的单元结构数/ B链段中含有的氧乙烯结构数）的比例 在所述至少2种油墨组合物的每一种中，所述油墨组合物中所含的嵌段共聚物中固含量比较高的固体成分浓度高于含有较低固含量浓度的油墨组合物中的嵌段共聚物。

公开(公告)号：US07528180B2

公开(公告)日：2009-05-05

申请号：US11220359

申请日：2005-09-06

申请人： Takeshi Okada ,  Kohei Watanabe

发明人： Takeshi Okada ,  Kohei Watanabe

IPC分类号： A61K9/16 ,  B05D1/32 ,  B41J2/01 ,  B41J2/175 ,  C08J3/00 ,  C08K3/20 ,  C08L31/00 ,  C08L33/00 ,  C09D5/02 ,  C09D11/00 ,  G01D11/00

CPC分类号： C09D11/40 ,  Y10S524/906

摘要： Disclosed herein is an ink set for use in ink-jet recording, which comprises at least 2 ink compositions the solid content concentrations of which are different by more than 2% by mass. The at least 2 ink compositions each comprise an aqueous medium, a pigment and a dispersant for dispersing the pigment. The dispersant is an amphiphilic block copolymer having an A segment that is a hydrophobic segment, a B segment that is a nonionic hydrophilic segment, and a C segment that is an ionic hydrophilic segment. The number of unit structures of the B segment of the amphiphilic block copolymer contained in each of the at least 2 ink compositions is smaller in the amphiphilic block copolymer contained in the ink composition having a relatively high solid content concentration than in the amphiphilic block copolymer contained in the ink composition having a relatively low solid content concentration.

摘要翻译： 本文公开了一种用于喷墨记录的油墨组，其包含至少2种固体含量浓度超过2质量％的油墨组合物。 所述至少2种油墨组合物各自包含水性介质，颜料和用于分散颜料的分散剂。 分散剂是具有作为疏水链段的A链段，作为非离子亲水链段的B链段和作为离子性亲水链段的C链段的两亲性嵌段共聚物。 包含在至少两种油墨组合物中的两亲性嵌段共聚物的B链段的单元结构的数量在包含在具有相对高的固体含量浓度的油墨组合物中的两亲嵌段共聚物中比在包含的两亲嵌段共聚物中更小 在具有相对低的固体含量浓度的油墨组合物中。

公开(公告)号：US20060058422A1

公开(公告)日：2006-03-16

申请号：US11220359

申请日：2005-09-06

申请人： Takeshi Okada ,  Kohei Watanabe

发明人： Takeshi Okada ,  Kohei Watanabe

IPC分类号： C03C17/00 ,  C09D11/00

CPC分类号： C09D11/40 ,  Y10S524/906

摘要： Disclosed herein is an ink set for use in ink-jet recording, which comprises at least 2 ink compositions the solid content concentrations of which are different by more than 2% by mass. The at least 2 ink compositions each comprise an aqueous medium, a pigment and a dispersant for dispersing the pigment. The dispersant is an amphiphilic block copolymer having an A segment that is a hydrophobic segment, a B segment that is a nonionic hydrophilic segment, and a C segment that is an ionic hydrophilic segment. The number of unit structures of the B segment of the amphiphilic block copolymer contained in each of the at least 2 ink compositions is smaller in the amphiphilic block copolymer contained in the ink composition having a relatively high solid content concentration than in the amphiphilic block copolymer contained in the ink composition having a relatively low solid content concentration.

公开(公告)号：US20060052481A1

公开(公告)日：2006-03-09

申请号：US11220179

申请日：2005-09-06

申请人： Kohei Watanabe ,  Takeshi Okada

发明人： Kohei Watanabe ,  Takeshi Okada

IPC分类号： C03C17/00 ,  C09D11/00

CPC分类号： C09D11/40

摘要： Disclosed herein is an ink set for use in ink-jet recording, which comprises at least 2 ink compositions the solid content concentrations of which are different by more than 2% by mass. The said at least 2 ink compositions each comprise an aqueous medium, a pigment and a dispersant for dispersing the pigment, and the dispersant is a block copolymer having an A segment that is a hydrophobic segment, a B segment that is an oxyethylene-structure-containing nonionic hydrophilic segment, and a C segment that is an ionic hydrophilic segment. The ratio of the number of unit structures of the A segment to the number of oxyethylene structures contained in the B segment (the number of unit structures of the A segment/the number of oxyethylene structures contained in the B segment) of the block copolymer contained in each of said at least 2 ink compositions is higher in the block copolymer contained in the ink composition having a relatively high solid content concentration than in the block copolymer contained in the ink composition having a relatively low solid content concentration.

公开(公告)号：US10227337B2

公开(公告)日：2019-03-12

申请号：US13397759

申请日：2012-02-16

申请人： Toshio Tanaka ,  Kohei Watanabe ,  Tsuyoshi Nomoto ,  Mie Okano ,  Taichi Shintou ,  Takeshi Miyazaki ,  Yuhei Nishimura ,  Yasuhito Shimada

发明人： Toshio Tanaka ,  Kohei Watanabe ,  Tsuyoshi Nomoto ,  Mie Okano ,  Taichi Shintou ,  Takeshi Miyazaki ,  Yuhei Nishimura ,  Yasuhito Shimada

IPC分类号： C07D417/06 ,  C07D417/14 ,  C09B23/04 ,  C09B23/06 ,  G01N33/50

摘要： Provided is an evaluation probe capable of optically evaluating permeability of a substance through a central nervous system tissue. Also provided is an evaluation method for permeability of a substance through a central nervous system tissue using an evaluation probe for central nervous system permeability. Also provided is a screening method using an evaluation probe for central nervous system permeability. The evaluation probe for central nervous system permeability includes, as an active ingredient, at least one kind of compound represented by the following general formula (1).

公开(公告)号：US08323973B2

公开(公告)日：2012-12-04

申请号：US10582099

申请日：2004-12-13

申请人： Qsamu Kanome ,  Kohei Watanabe ,  Takeshi Miyazaki ,  Tomoyo Fujiyama ,  Ryoichi Matsuda

发明人： Qsamu Kanome ,  Kohei Watanabe ,  Takeshi Miyazaki ,  Tomoyo Fujiyama ,  Ryoichi Matsuda

IPC分类号： C12N5/00

CPC分类号： C12N5/0068 ,  C12M23/12 ,  C12M23/34 ,  C12N2501/105 ,  C12N2501/115 ,  C12N2501/155 ,  C12N2533/30 ,  C12N2533/32 ,  C12Q1/045

摘要： A cell culture substrate having at least one area for culturing a cell on a substrate, characterized in that the culturing area comprises an area releasably holding a biologically active substance having a biological activity to the cell and an area for immobilizing a biologically active substance having a biological activity to the cell.

摘要翻译： 一种细胞培养基质，具有至少一个用于在基质上培养细胞的区域，其特征在于，培养区域包括可释放地保持对细胞具有生物活性的生物活性物质的区域和用于固定具有生物活性物质的区域 对细胞的生物活性。

公开(公告)号：US20110189096A1

公开(公告)日：2011-08-04

申请号：US13084997

申请日：2011-04-12

申请人： Kohei Watanabe ,  Taichi Shintou ,  Tsuyoshi Nomoto ,  Takeshi Miyazaki ,  Mie Okano ,  Toshio Tanaka ,  Yuhei Nishimura ,  Yasuhito Shimada

发明人： Kohei Watanabe ,  Taichi Shintou ,  Tsuyoshi Nomoto ,  Takeshi Miyazaki ,  Mie Okano ,  Toshio Tanaka ,  Yuhei Nishimura ,  Yasuhito Shimada

IPC分类号： A61K49/00 ,  C07D221/18 ,  C07D491/147 ,  C07D221/14 ,  C07D417/10 ,  C07D417/06

CPC分类号： A61K49/0032 ,  A61K49/0039 ,  A61K49/006 ,  C07D417/06 ,  G01N33/50 ,  G01N33/58 ,  G01T1/161

摘要： To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).

摘要翻译： 提供标记中枢神经组织系统的中枢神经系统组织标记组合物。 此外，本发明的另一个目的是提供一种非侵入性标记中枢神经组织系统的方法。 此外，本发明的另一个目的是提供一种使用上述中枢神经系统组织标记组合物的筛选方法。 一种中枢神经系统组织标记组合物，含有由通式（1）或（7）表示的至少一种化合物作为活性成分。

公开(公告)号：US20100300547A1

公开(公告)日：2010-12-02

申请号：US12788168

申请日：2010-05-26

申请人： Tsuyoshi Nomoto ,  Kohei Watanabe ,  Takeshi Miyazaki ,  Toshio Tanaka ,  Yasuhito Shimada

发明人： Tsuyoshi Nomoto ,  Kohei Watanabe ,  Takeshi Miyazaki ,  Toshio Tanaka ,  Yasuhito Shimada

IPC分类号： F17D3/00 ,  B23Q3/00 ,  B65D47/18

CPC分类号： B65D19/002 ,  B65D19/0002 ,  Y10T137/0318

摘要： It is intended to provide an object-holding sheet and an object-treating equipment, which are useful for arranging objects such as biological materials (e.g., cells, embryos or individuals) or particles having the similar size thereto and efficiently conducting procedures such as analysis and fractionation on the objects. The present invention provides an object-holding sheet for holding two or more objects, the object-holding sheet including: a sheet member having two or more through-holes; and an anti-drop member corresponding to each of the holes, wherein the holes have a size that enables only one of the objects to be held, and the anti-drop member is disposed in the vicinity of one opening of each of the holes so as not to permit the object held in each of the holes to pass through the opening.

摘要翻译： 旨在提供一种对象保持用片材和物体治疗装置，其可用于排列诸如生物材料（例如细胞，胚胎或个体）的物体或具有相似尺寸的颗粒，并且有效地进行诸如分析 并对物体进行分馏。 本发明提供一种用于保持两个或多个物体的物体保持片，所述物体保持片包括：具有两个或更多个通孔的片状构件; 以及对应于每个孔的防滴落构件，其中，所述孔具有能够仅保持一个物体的尺寸，并且防滴落构件设置在每个孔的一个开口附近，因此 因为不允许保持在每个孔中的物体通过开口。