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公开(公告)号:US11248246B2
公开(公告)日:2022-02-15
申请号:US16979568
申请日:2019-03-08
Inventor: Kyoung Heon Kim , Dong-Hyun Kim
Abstract: The present invention relates to a novel beta-glucosidase for producing glucose and a laminarioligosaccharide from seaweed. More particularly, the present invention may produce glucose from a beta-glucosidase exhibiting transglycosylase activity while showing exo-type glucanase activity against beta-glucan, as well as produce a laminarioligosaccharide by exhibiting transglycosylase activity against laminarin under different reaction conditions.
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公开(公告)号:US12110494B2
公开(公告)日:2024-10-08
申请号:US17273621
申请日:2019-09-05
Inventor: Kyoung Heon Kim , Yong Su Jin , Dong-Hyun Kim , Eun-Ju Yun
IPC: C12N15/81 , C07K14/195 , C12N9/24 , C12N9/38 , C12P7/18
CPC classification number: C12N15/81 , C07K14/195 , C12N9/2471 , C12P7/18 , C12Y101/01021 , C12Y302/01023
Abstract: The present invention relates to a method for biologically producing, from seaweeds, 3,6-anhydro-L-galactitol (L-AHGol) which is a novel sugar alcohol, and agarobititol (ABol) which is in a disaccharide form having 3,6-anhydro-L-galactitol (L-AHGol) as a reducing end, by using a genetic engineering technique in GRAS strains.
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公开(公告)号:US11872253B2
公开(公告)日:2024-01-16
申请号:US17724386
申请日:2022-04-19
Inventor: Kyoung Heon Kim , Yong-Su Jin , Eun-Ju Yun , Dong-Hyun Kim , Sora Yu , Kyung-Mun Cho , Na Jeong Park
IPC: C12P19/00 , A61K35/44 , A23L33/125 , A23L33/135 , A23L33/00 , A61K35/745 , A61K47/26 , A61K35/00
CPC classification number: A61K35/44 , A23L33/125 , A23L33/135 , A23L33/40 , A61K35/745 , A61K47/26 , C12P19/00 , A23V2002/00 , A23V2400/529 , A61K2035/115
Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.
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公开(公告)号:US11458152B2
公开(公告)日:2022-10-04
申请号:US16985850
申请日:2020-08-05
Inventor: Kyoung Heon Kim , Eun-Ju Yun , Sora Yu , Dong-Hyun Kim , Sang-Hyun Lee , Jung Yeon Kim
IPC: A61K8/73 , A61Q11/00 , A61K31/702 , A23L33/125 , A61P1/02 , A61P31/04 , A61K8/60 , A61K9/00 , A61K31/7016 , A61K31/729
Abstract: The present invention relates to a use of an agarobiose or agarooligosaccharides having anticariogenic activity. More specifically, a lower concentration of agarobiose or agarooligosaccharides than the concentration of xylitol suppresses the growth of Streptococcus mutans and suppresses acid production, and thus can be used for anti-cariogenic purposes.
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公开(公告)号:US20220241349A1
公开(公告)日:2022-08-04
申请号:US17724386
申请日:2022-04-19
Inventor: Kyoung Heon KIM , Yong-Su Jin , Eun-Ju Yun , Dong-Hyun Kim , Sora Yu , Kyung-mun Cho , Na Jeong Park
IPC: A61K35/74 , A23L33/125 , A23L33/135 , A23L33/00 , A61K35/745 , A61K47/26 , C12P19/00
Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.
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公开(公告)号:US20220220522A1
公开(公告)日:2022-07-14
申请号:US17586649
申请日:2022-01-27
Inventor: Kyoung Heon KIM , Sung-Hyun Lee , Dong-Hyun Kim , Enu-Ju Yun
Abstract: The present invention relates to a method for producing anhydrous galactose derived from seaweed, and provides an improved production yield of 3,6-anhydro-L-galactose (AHG) from agarose or agar through multiple steps involving acid hydrolysis of agar or agarose for producing agarobiose, neutralization of the acid hydrolysate, and purification of AHG using a microorganism metabolizing galactose after enzymatic hydrolysis of agarobiose.
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公开(公告)号:US11337999B2
公开(公告)日:2022-05-24
申请号:US16764742
申请日:2018-11-15
Inventor: Kyoung Heon Kim , Yong-Su Jin , Eun-Ju Yun , Dong-Hyun Kim , Sora Yu , Kyung-mun Cho , Na Jeong Park
IPC: A61K35/741 , A61K35/74 , A23L33/125 , A23L33/135 , A23L33/00 , A61K35/745 , A61K47/26 , C12P19/00 , A61K35/00
Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.
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公开(公告)号:US11268114B2
公开(公告)日:2022-03-08
申请号:US16467129
申请日:2017-11-24
Inventor: Kyoung Heon Kim , Sang-Hyun Lee , Dong-Hyun Kim , Eun-Ju Yun
Abstract: The present invention relates to a method for producing anhydrous galactose derived from seaweed, and provides an improved production yield rate of 3,6-anhydro-L-galactose by using microorganisms during acid treatment, neutralization, and purification after enzymatic hydrolysis, of agarose or agar.
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公开(公告)号:US20200376012A1
公开(公告)日:2020-12-03
申请号:US16985850
申请日:2020-08-05
Inventor: Kyoung Heon Kim , Eun-Ju Yun , Sora Yu , Dong-Hyun Kim , Sang-Hyun Lee , Jung Yeon Kim
IPC: A61K31/702 , A23L33/125 , A61P1/02 , A61P31/04 , A61K8/60 , A61K8/73 , A61K9/00 , A61K31/7016 , A61K31/729 , A61Q11/00
Abstract: The present invention relates to a use of an agarobiose or agarooligosaccharides having anticariogenic activity. More specifically, a lower concentration of agarobiose or agarooligosaccharides than the concentration of xylitol suppresses the growth of Streptococcus mutans and suppresses acid production, and thus can be used for anti-cariogenic purposes.
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