公开(公告)号：US11872253B2

公开(公告)日：2024-01-16

申请号：US17724386

申请日：2022-04-19

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon Kim ,  Yong-Su Jin ,  Eun-Ju Yun ,  Dong-Hyun Kim ,  Sora Yu ,  Kyung-Mun Cho ,  Na Jeong Park

IPC: C12P19/00 ,  A61K35/44 ,  A23L33/125 ,  A23L33/135 ,  A23L33/00 ,  A61K35/745 ,  A61K47/26 ,  A61K35/00

CPC classification number: A61K35/44 ,  A23L33/125 ,  A23L33/135 ,  A23L33/40 ,  A61K35/745 ,  A61K47/26 ,  C12P19/00 ,  A23V2002/00 ,  A23V2400/529 ,  A61K2035/115

Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.

公开(公告)号：US20220241349A1

公开(公告)日：2022-08-04

申请号：US17724386

申请日：2022-04-19

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon KIM ,  Yong-Su Jin ,  Eun-Ju Yun ,  Dong-Hyun Kim ,  Sora Yu ,  Kyung-mun Cho ,  Na Jeong Park

IPC: A61K35/74 ,  A23L33/125 ,  A23L33/135 ,  A23L33/00 ,  A61K35/745 ,  A61K47/26 ,  C12P19/00

Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.

公开(公告)号：US11337999B2

公开(公告)日：2022-05-24

申请号：US16764742

申请日：2018-11-15

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon Kim ,  Yong-Su Jin ,  Eun-Ju Yun ,  Dong-Hyun Kim ,  Sora Yu ,  Kyung-mun Cho ,  Na Jeong Park

IPC: A61K35/741 ,  A61K35/74 ,  A23L33/125 ,  A23L33/135 ,  A23L33/00 ,  A61K35/745 ,  A61K47/26 ,  C12P19/00 ,  A61K35/00

Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.

公开(公告)号：US12077792B2

公开(公告)日：2024-09-03

申请号：US17054969

申请日：2019-05-15

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS ,  KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Yong-Su Jin ,  Jingjing Liu ,  Sora Yu ,  Eun Ju Yun ,  Suryang Kwak ,  Kyoung Heon Kim ,  Jaewon Lee

IPC: C12N9/88 ,  C07K14/395 ,  C12N1/21 ,  C12N9/04 ,  C12N9/10 ,  C12N15/81 ,  C12P19/18

CPC classification number: C12N9/88 ,  C07K14/395 ,  C12N9/0006 ,  C12N9/1051 ,  C12N15/81 ,  C12P19/18 ,  C12Y101/01271 ,  C12Y402/01047 ,  C12N2800/102

Abstract: Compositions and methods are provided for producing 2′fucosyliaciose and L-fucose from recombinant microorganisms.

公开(公告)号：US11504386B2

公开(公告)日：2022-11-22

申请号：US16765359

申请日：2018-11-15

Applicant: Korea University Research and Business Foundation

Inventor： Kyoung Heon Kim ,  Yong-Su Jin ,  Eun-Ju Yun ,  Sora Yu ,  Jaewon Lee

IPC: A61K31/7004 ,  A23L33/125 ,  A61K8/60 ,  A61K31/7016 ,  A61K31/729 ,  C12P19/04 ,  C12P19/18

Abstract: The present invention relates to a preparation method for various novel fucosyl oligosaccharides and a use thereof. More specifically, the present invention allows a preparation of various novel fucosyl oligosaccharides through an enzymatic reaction with α-1,2-fucosyltransferase using a GDP-L-fucose donor and various glucose acceptors and an establishment of probiotic characteristics thereof, and thus has an effect of providing uses as materials for medicines, food, cosmetic products, and the like.