Hollow yarn membrane used for blood purification and blood purifier
    4.
    发明授权
    Hollow yarn membrane used for blood purification and blood purifier 失效
    中空丝膜用于血液净化和血液净化器

    公开(公告)号:US6042783A

    公开(公告)日:2000-03-28

    申请号:US973243

    申请日:1998-02-03

    IPC分类号: D01F6/76 A61M1/14

    摘要: A polysulfone hollow fiber membrane for blood purification which has no danger that any component of the membrane dissolves out, and which can be used suitably or hemodialysis and blood filtration and remove selectively and efficiently low-molecular-weight proteins having molecular weight of 10,000 to 30,000 contained in blood, as well as a blood purifier which can be used suitably as a hemodialyzer, a filter for hemodiafiltration and a blood filter are provided. The hollow fiber membrane comprises a polysulfone resin, wherein there are slit-shaped micropores having an average width of 0.02 to 0.15 .mu.m on the inner surface thereof; there are micropores having an average pore size of 0.1 to 1 .mu.m on the outer surface thereof; the inside thereof has a sponge-like structure; there are no large voids having a diameter of more than 10 .mu.m on the inner and outer surface thereof and inside the membrane; water permeability thereof is 400 to 2,500 ml/m.sup.2 .multidot.hr.multidot.mmHg; and a permeation rato for the total proteins is 1% or less. The blood puifier contains the hollow fiber membrane put into a cylindrical housing which is equipped with a blood inlet and a blood outlet, and either a dialysate solution inlet and a dialysate solution outlet or a filtrate outlet.

    摘要翻译: PCT No.PCT / JP97 / 00924 Sec。 371日期1998年2月3日 102(e)日期1998年2月3日PCT 1997年3月21日PCT公布。 公开号WO97 / 34687 日期1997年9月25日一种用于血液净化的聚砜中空纤维膜,其没有膜的任何成分溶解的危险,并且可以适当地使用,或者可以使用血液透析和血液过滤,并且选择性和有效地除去具有分子的低分子量蛋白质 血液中含有10,000〜30,000份的重量,以及适合用作血液透析器的血液净化器,血液透析滤过滤器和血液过滤器。 中空纤维膜包括聚砜树脂,其中在其内表面上具有平均宽度为0.02至0.15μm的狭缝状微孔; 在其外表面上具有平均孔径为0.1-1μm的微孔; 其内部具有海绵状结构; 在其内表面和外表面以及膜内均不存在直径大于10μm的大空隙; 其透水性为400〜2500ml / m 2×hr×mmHg; 并且总蛋白质的渗透量为1%以下。 血液循环器包含放入装有血液入口和血液出口的圆柱形壳体中的中空纤维膜,以及透析液溶液入口和透析液溶液出口或滤液出口。