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    Methods for forming dyed microspheres and populations of dyed microspheres
    1.
    发明授权
    Methods for forming dyed microspheres and populations of dyed microspheres 有权
    形成染色微球体和染色微球体群体的方法

    公开(公告)号：US08361169B2

    公开(公告)日：2013-01-29

    申请号：US13246486

    申请日：2011-09-27

    申请人： Kurt D. Hoffacker ,  Ananda G. Lugade ,  Ewald Terpetschnig

    发明人： Kurt D. Hoffacker ,  Ananda G. Lugade ,  Ewald Terpetschnig

    IPC分类号： C07C247/00

    CPC分类号： C09B69/10 ,  C08F8/00 ,  C09B67/0097 ,  D06P1/008 ,  G01N33/585 ,  C08F212/08

    摘要： Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.

    摘要翻译： 提供了形成染色微球的各种方法。 一种方法包括使用热或光活化与染料偶联的化学结构，以在微球存在下形成反应中间体。 反应中间体共价连接到微球的聚合物上，从而将染料偶联到聚合物上并形成染色的微球。 提供用于形成耦合到分子的染色微球的其它方法。 除了在染色的微球的外表面上合成分子之外，这些方法包括如上所述染色微球。 还提供了一批染色微球。 群体的每个染色的微球包括通过化学结构连接到每个染色微球的聚合物上的染料。 由染料染色的微球体的染料特性的变异系数小于约10％。

    METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES
    3.
    发明申请
    METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES 有权
    用于形成染色微球的人造粒的方法

    公开(公告)号：US20120035328A1

    公开(公告)日：2012-02-09

    申请号：US13246486

    申请日：2011-09-27

    申请人： Kurt D. Hoffacker ,  Ananda G. Lugade ,  Ewald Terpetschnig

    发明人： Kurt D. Hoffacker ,  Ananda G. Lugade ,  Ewald Terpetschnig

    IPC分类号： C08F12/30 ,  C07D403/08 ,  C07C311/49

    CPC分类号： C09B69/10 ,  C08F8/00 ,  C09B67/0097 ,  D06P1/008 ,  G01N33/585 ,  C08F212/08

    摘要： Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.

    摘要翻译： 提供了形成染色微球的各种方法。 一种方法包括使用热或光活化与染料偶联的化学结构，以在微球存在下形成反应中间体。 反应中间体共价连接到微球的聚合物上，从而将染料偶联到聚合物上并形成染色的微球。 提供用于形成耦合到分子的染色微球的其它方法。 除了在染色的微球的外表面上合成分子之外，这些方法包括如上所述染色微球。 还提供了一批染色微球。 群体的每个染色的微球包括通过化学结构连接到每个染色微球的聚合物上的染料。 由染料染色的微球体的染料特性的变异系数小于约10％。

    Methods for forming dyed microspheres and populations of dyed microspheres
    6.
    发明授权
    Methods for forming dyed microspheres and populations of dyed microspheres 有权
    形成染色微球体和染色微球体群体的方法

    公开(公告)号：US08038734B2

    公开(公告)日：2011-10-18

    申请号：US11247942

    申请日：2005-10-11

    申请人： Kurt D. Hoffacker ,  Ananda G. Lugade ,  Ewald Terpetschnig

    发明人： Kurt D. Hoffacker ,  Ananda G. Lugade ,  Ewald Terpetschnig

    IPC分类号： D06P3/00

    CPC分类号： C09B69/10 ,  C08F8/00 ,  C09B67/0097 ,  D06P1/008 ,  G01N33/585 ,  C08F212/08

    摘要： Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.

    摘要翻译： 提供了形成染色微球的各种方法。 一种方法包括使用热或光活化与染料偶联的化学结构，以在微球存在下形成反应中间体。 反应中间体共价连接到微球的聚合物上，从而将染料偶联到聚合物上并形成染色的微球。 提供用于形成耦合到分子的染色微球的其它方法。 除了在染色的微球的外表面上合成分子之外，这些方法包括如上所述染色微球。 还提供了一批染色微球。 群体的每个染色的微球包括通过化学结构连接到每个染色微球的聚合物上的染料。 由染料染色的微球体的染料特性的变异系数小于约10％。