NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT
    5.
    发明申请
    NOVEL BIPHENYL DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES OR AUTOIMMUNE DISEASES COMPRISING THE SAME AS ACTIVE INGREDIENT 有权
    新颖的联苯衍生物或药物可接受的盐,以及用于预防或治疗包含其作为活性成分的炎症性疾病或自身免疫性疾病的药物组合物

    公开(公告)号:US20150291509A1

    公开(公告)日:2015-10-15

    申请号:US14237256

    申请日:2012-08-06

    CPC classification number: C07C233/47 C07D295/192 C07D295/195

    Abstract: The present invention relates to a novel biphenyl derivative or a pharmaceutically acceptable salt thereof, a pharmaceutical composition for preventing or treating inflammatory diseases or autoimmune diseases comprising the same as an active ingredient, and methods for treating inflammatory disease or autoimmune diseases with the pharmaceutical composition. Novel biphenyl derivatives according to the present invention promote the phagocytosis of macrophages and inhibit the chemotaxis to exhibit excellent inflammation terminating and anti-inflammatory effects and thus can be effectively used as therapeutic agents for inflammatory diseases or autoimmune diseases.

    Abstract translation: 本发明涉及一种新型的联苯衍生物或其药学上可接受的盐,用于预防或治疗炎性疾病的药物组合物或包含其作为活性成分的自身免疫性疾病,以及用药物组合物治疗炎性疾病或自身免疫性疾病的方法。 根据本发明的新型联苯衍生物促进巨噬细胞的吞噬作用并抑制趋化性表现出优异的炎症终止和抗炎作用,因此可以有效地用作炎性疾病或自身免疫性疾病的治疗剂。

    Flash memory device
    9.
    发明申请
    Flash memory device 有权
    闪存设备

    公开(公告)号:US20060139997A1

    公开(公告)日:2006-06-29

    申请号:US11299063

    申请日:2005-12-09

    CPC classification number: G11C16/3418 G11C16/0483 G11C16/3427

    Abstract: A flash memory device comprises a first group of dummy memory cells disposed between source selection transistors, which are coupled to a source selection line, and memory cells coupled to a first wordline. The flash memory device further comprises a second group of dummy memory cells disposed between drain selection transistors, which are coupled to a drain selection line, and memory cells coupled to the last wordline. The flash memory device is configured to prevent program disturbance in deselected cell strings and degradation of programming/erasing speeds in a selected cell string.

    Abstract translation: 闪速存储器件包括设置在源选择晶体管之间的第一组虚拟存储器单元,其耦合到源选择线,以及耦合到第一字线的存储器单元。 闪速存储器件还包括设置在漏极选择晶体管之间的第二组虚设存储器单元,其耦合到漏极选择线,以及耦合到最后一个字线的存储器单元。 闪存器件被配置为防止未选择的单元串中的程序干扰以及所选单元串中编程/擦除速度的劣化。

    Waveguide type optical device using large 3rd non-linear optical material and method for operating the same
    10.
    发明申请
    Waveguide type optical device using large 3rd non-linear optical material and method for operating the same 有权
    使用大型第3非线性光学材料的波导型光学器件及其操作方法

    公开(公告)号:US20050105864A1

    公开(公告)日:2005-05-19

    申请号:US10987709

    申请日:2004-11-12

    Abstract: Disclosed is a waveguide type optical device utilizing a nonlinear refractive index change according to a large 3rd order nonlinear optical phenomenon. The waveguide type optical device includes a signal beam waveguide through which a signal beam propagates; and a pump beam waveguide through which a pump beam propagates, wherein the pump beam waveguide is disposed adjacent to the signal beam waveguide so that the pump beam can be coupled to the signal beam waveguide, the signal beam waveguide is made of nonlinear optical materials with large 3rd order nonlinear optical property and the pump beam waveguide is made of linear optical materials, and the wavelength range of the signal beam is different from that of the pump beam. By such a structure, the pump beam is coupled to one arm of the signal beam waveguide, thereby generating a 3rd nonlinear phenomenon on one arm of the waveguide through which the signal beam passes. Therefore, the waveguide optical device which implements an all-optical communication device operating as an optical device and can be integrated is provided.

    Abstract translation: 公开了一种使用根据大的3阶非线性光学现象的非线性折射率变化的波导型光学器件。 波导型光学器件包括信号光束波导,信号光束通过该波导波导传播; 以及泵浦光束通过其传播的泵浦波导,其中所述泵浦波导与所述信号光束波导相邻设置,使得所述泵浦波束可以耦合到所述信号波导管,所述信号波束波导由非线性光学材料制成, 大的3阶非线性光学特性和泵浦波导由线性光学材料制成,信号光束的波长范围与泵浦光束的波长范围不同。 通过这种结构,泵浦光束耦合到信号光束波导的一个臂,从而在信号光束通过的波导的一个臂上产生第三非线性现象。 因此,提供了实现作为光学装置工作并可以集成的全光通信装置的波导光学装置。

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