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    COSMETIC USE OF DERMICIDIN, OR ANALOGUES OR FRAGMENTS THEREOF, FOR THE PREVENTION AND/OR TREATMENT AND DIAGNOSIS OF OILY SKIN AND AESTHETIC SKIN DISORDERS ASSOCIATED THEREWITH
    1.
    发明申请
    COSMETIC USE OF DERMICIDIN, OR ANALOGUES OR FRAGMENTS THEREOF, FOR THE PREVENTION AND/OR TREATMENT AND DIAGNOSIS OF OILY SKIN AND AESTHETIC SKIN DISORDERS ASSOCIATED THEREWITH 审中-公开
    灭菌剂或其类似物或其片剂的化学使用，用于预防和/或治疗和诊断与之相关的油性皮肤和美白皮肤病

    公开(公告)号：US20160361384A1

    公开(公告)日：2016-12-15

    申请号：US14897328

    申请日：2014-06-16

    Applicant: L'OREAL

    Inventor： Audrey Gueniche ,  Dominique Bernard ,  Mark Donovan

    IPC: A61K38/17 ,  G01N33/94 ,  C07K14/47 ,  G01N33/68 ,  A61Q19/00 ,  A61K8/64

    CPC classification number: A61K38/1709 ,  A61K8/64 ,  A61K38/4873 ,  A61Q19/008 ,  C07K14/47 ,  G01N33/6881 ,  G01N33/9446 ,  G01N2500/00 ,  G01N2800/20

    Abstract: Cosmetic or therapeutic, in particular dermatological, use of dermicidin, or analogues or fragments thereof, for preventing the appearance of imperfections, and also for the treatment and diagnosis of acneic skin or acne-prone skin. The subject matter of the present invention is in particular the use of a cosmetic and/or therapeutic, in particular dermatological, composition containing at least one amino acid sequence of dermicidin, or of an analogue or fragment thereof, or of at least one nucleic acid sequence encoding the sequence, for preventing the appearance of imperfections, and also for the treatment and/or prevention and/or diagnosis of acneic and/or oily or acne-prone and/or oily skin. It also related to a method for applying the abovementioned cosmetic composition for the prevention of the appearance of imperfections and the treatment of acne-prone and/or oily skin. It additionally relates to a method for treating acneic skin comprising the topical application to said skin of the pharmaceutical composition for the treatment of acneic and/or oily skin. The subject matter of the present invention is also the use of a biomarker for the diagnosis of acneic and/or oily or acne-prone and/or oily skin.

    Abstract translation: 化妆品或治疗剂，特别是皮肤病学用途的皮肤霉素或其类似物或片段，用于防止缺陷的出现，以及用于治疗和诊断痤疮皮肤或易痤疮的皮肤。 本发明的主题特别是使用含有至少一种皮肤霉素或其类似物或片段的氨基酸序列或至少一种核酸的化妆品和/或治疗剂，特别是皮肤病学组合物 编码序列的序列，用于防止缺陷的出现，以及用于治疗和/或预防和/或诊断痤疮和/或油性或痤疮倾向和/或油性皮肤。 它还涉及应用上述化妆品组合物以防止缺陷的出现和治疗痤疮倾向和/或油性皮肤的方法。 本发明还涉及一种治疗痤疮皮肤的方法，其包括用于治疗痤疮和/或油性皮肤的药物组合物的所述皮肤的局部应用。 本发明的主题也是生物标志物用于诊断痤疮和/或油性或痤疮倾向和/或油性皮肤的用途。

    COMPOUNDS FOR DRY SKIN AND ANTI-AGEING APPLICATION
    2.
    发明申请
    COMPOUNDS FOR DRY SKIN AND ANTI-AGEING APPLICATION 有权
    用于干性皮肤和抗老化应用的化合物

    公开(公告)号：US20150148356A1

    公开(公告)日：2015-05-28

    申请号：US14406365

    申请日：2013-06-05

    Applicant: L'OREAL

    Inventor： Xavier Marat ,  Benoit Muller ,  Agnès Thomas-Collignon ,  Dominique Bernard

    IPC: C07D471/04

    CPC classification number: C07D471/04 ,  A61K8/4953 ,  A61Q19/007 ,  A61Q19/08

    Abstract: The present invention relates to the cosmetic use, as agent for preventing and/or treating an aesthetic defect in the skin and/or its appendages that is associated with an imbalance in the differentiation and/or proliferation of the cells of an epidermis, of an effective amount of at least one compound represented by one of the general formulae, (Ia) or (Ib)

    Abstract translation: 本发明涉及化妆品用途，作为用于预防和/或治疗与皮肤细胞分化和/或增殖不平衡相关的皮肤和/或其附属物的美观缺陷的试剂， 有效量的由通式（Ia）或（Ib）之一表示的至少一种化合物，

    USE OF COMPLEX FORMS OF CALMODULIN-LIKE SKIN PROTEIN CLSP
    5.
    发明申请
    USE OF COMPLEX FORMS OF CALMODULIN-LIKE SKIN PROTEIN CLSP 审中-公开
    使用钙柔霉素样皮肤蛋白CLSP的复合形式

    公开(公告)号：US20140348816A1

    公开(公告)日：2014-11-27

    申请号：US14327799

    申请日：2014-07-10

    Applicant: L'OREAL

    Inventor： Mark DONOVAN ,  Dominique Bernard

    IPC: G01N33/68

    CPC classification number: G01N33/6881 ,  A61K8/64 ,  A61Q19/08 ,  G01N2333/4727 ,  G01N2800/20

    Abstract: The invention also relates to the use of these complex forms for the purposes of screening for biological or chemical compounds capable of modulating a biological activity of said complex forms and/or for preparing and/or improving a pluristratified cell model.

    Abstract translation: 本发明还涉及这些复合物形式用于筛选能够调节所述复合物形式的生物活性的生物或化学化合物和/或用于制备和/或改善多分化细胞模型的用途。

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