公开(公告)号：US20220259383A1

公开(公告)日：2022-08-18

申请号：US17733698

申请日：2022-04-29

Applicant: LG CHEM, LTD.

Inventor： Jung Yun CHOI ,  Hye Ok KANG ,  Donggyun KANG ,  Younghyun CHO ,  Jae Hyung KIM ,  Chul Woong KIM ,  In Young HUH

IPC: C08G81/02 ,  C08G18/28 ,  C08G18/60 ,  C08G18/73

Abstract: Provided is a lactic acid-based block copolymer which is biodegradable while having excellent mechanical properties.

公开(公告)号：US20200172680A1

公开(公告)日：2020-06-04

申请号：US16615625

申请日：2018-12-31

Applicant: LG CHEM, LTD.

Inventor： Jung Yun CHOI ,  Hye Ok KANG ,  Donggyun KANG ,  Younghyun CHO ,  Jae Hyung KIM ,  Chul Woong KIM ,  In Young HUH

IPC: C08G81/02 ,  C08G18/28 ,  C08G18/73 ,  C08G18/60

Abstract: Provided is a lactic acid-based block copolymer which is biodegradable while having excellent mechanical properties.

公开(公告)号：US20230340547A1

公开(公告)日：2023-10-26

申请号：US18028037

申请日：2021-11-05

Applicant: LG CHEM, LTD.

Inventor： Kyung Muk LEE ,  Jae Hyung KIM ,  In Young HUH

IPC: C12P7/52 ,  C12N9/02 ,  C12N9/88 ,  C12N15/52

CPC classification number: C12P7/52 ,  C12N9/0008 ,  C12Y102/01003 ,  C12N9/88 ,  C12Y402/0103 ,  C12N15/52

Abstract: Provided is a two-step production method for 3-HP, comprising: a first step of culturing cells at a high concentration; and a second step of producing 3-HP using the high concentration-cultured cells as a catalyst, in which during the two-step culture, the energy and/or coenzyme balance are adjusted to produce 3-HP and/or improve the productivity of 3-HP. The productivity and yield of 3-HP can be improved.

公开(公告)号：US20230183418A1

公开(公告)日：2023-06-15

申请号：US15769045

申请日：2017-03-09

Applicant: LG CHEM,LTD

Inventor： Jae Hyung KIM ,  Dong Gyun KANG ,  Chul Woong KIM ,  Young Hyun CHO ,  Sung Joon OH ,  Jeong Kyu LEE ,  In Young HUH

IPC: C08G63/06 ,  C09D167/04 ,  C12P7/625 ,  C07K14/21

CPC classification number: C08G63/06 ,  C09D167/04 ,  C12P7/625 ,  C07K14/21 ,  C08G2230/00

Abstract: A biopolymer, which exists in a liquid phase at room temperature, a use thereof, and a preparation method therefor are provided.

公开(公告)号：US20200270649A1

公开(公告)日：2020-08-27

申请号：US16754480

申请日：2019-03-13

Applicant: LG CHEM, LTD.

Inventor： Hye Ok KANG ,  Donggyun KANG ,  Chul Woong KIM ,  In Young HUH ,  Jung Yun CHOI

IPC: C12P7/62 ,  C12N1/20 ,  C12N15/70 ,  C08G63/06

Abstract: Provided are a novel 3-hydroxypropionate-lactate block copolymer [P(3HP-b-LA)], and a method for preparing same, comprising: a) transforming a recombinant microorganism modified to be incapable of biosynthesizing lactic acid with a vector including a 3-hydroxypropionyl-CoA biosynthesis gene and a polyhydroxyalkanoate (PHA) synthetase gene, and a vector including a lactate biosynthesis gene and a gene of an enzyme that converts lactate to lactyl-CoA; (b) synthesizing poly(3-hydroxypropionate) (P(3HP)) by culturing the recombinant microorganism using a glycerol as a carbon source; and (c) inhibiting P(3HP) production by adding IPTG and glucose, and biosynthesizing polylactate (PLA) at the end of P(3HP) synthesized in step (b) by enabling the expression of a lactate biosynthesis enzyme and an enzyme that converts lactate to lactyl-CoA. Also provided is a recombinant microorganism produced in step a).

公开(公告)号：US20230250044A1

公开(公告)日：2023-08-10

申请号：US18010033

申请日：2022-01-13

Applicant: LG CHEM, LTD.

Inventor： Woochul JUNG ,  In Young HUH ,  Kyung Muk LEE ,  Donggyun KANG ,  Jae Hyung KIM

IPC: C07C51/43

CPC classification number: C07C51/43 ,  C07B2200/13

Abstract: Provided is a process of recovering 3-hydroxypropionic acid and a crystal of 3-hydroxypropionate, wherein the process includes the steps of: forming crystals of 3-hydroxypropionate in a concentrate containing 3-hydroxypropionic acid in an amount of 300 g/L or more in the presence of an alkali metal salt; and separating the crystals of 3-hydroxypropionate from the concentrate and converting into 3-hydroxypropionic acid.

公开(公告)号：US20220251612A1

公开(公告)日：2022-08-11

申请号：US17679007

申请日：2022-02-23

Applicant: LG CHEM, LTD.

Inventor： Hye Ok KANG ,  Donggyun KANG ,  Chul Woong KIM ,  In Young HUH ,  Jung Yun CHOI

IPC: C12P7/625 ,  C08G63/06 ,  C12N1/20 ,  C12N15/70 ,  C12N9/04 ,  C12N9/02 ,  C12N9/10 ,  C08G63/08 ,  C12N9/88

Abstract: The present invention relates to a novel 3-hydroxypropionate-lactate block copolymer [P(3HP-b-LA)], and a method for preparing same, and more specifically, provides a method for preparing a 3-hydroxypropionate-lactate block copolymer, and a 3-hydroxypropionate-lactate block copolymer produced thereby, the method comprising: a first culture step in which, by using recombinant E. coli improved so as to be incapable of biosynthesizing lactic acid, P(3HP) is biosynthesized at the early stage of culturing by having glycerol as a carbon source and through 3-hydroxypropionate-generating genes and an enhanced PHA synthase; and a second culture step in which P(3HP) production is inhibited by using a carbon catabolic repression system for selectively introducing only glucose into E. coli when glycerol and glucose are supplied together as carbon sources, and in which polylactate is biosynthesized to an interrupted P(3HP) terminus by the enabling of the expression of a lactate synthase and a lactyl-CoA converting enzyme through an IPTG induction system.