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公开(公告)号：US20210323994A1
公开(公告)日：2021-10-21
申请号：US17304883
申请日：2021-06-28
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Tom XU , Christopher TRINH , Carole BORNARTH , Brian EVANS , Mousumi RATH , Kathy TRAN
IPC: C07H21/02 , C12Q1/6876 , C12N15/10 , C12Q1/6809 , C12Q1/6834
Abstract: Method and compositions and kits for isolation, identification, and quantification of miRNAs and other small RNAs, including but not limited to, siRNAs, mRNAs, and snRNAs are disclosed. Methods of diagnosing a disease or its progression are also disclosed.
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公开(公告)号：US20210348215A1
公开(公告)日：2021-11-11
申请号：US17443033
申请日：2021-07-20
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Christopher TRINH , Tom XU , Yating SHI , Ferrier Nhat LE , Claire MARJORIBANKS
IPC: C12Q1/686 , C12Q1/6848
Abstract: A composition comprising a thermostable DNA polymerase; and a PCR inhibitor blocking agent, wherein the PCR inhibitor blocking agent is present in an amount effective to enhance tolerance of an assembled PCR to a PCR inhibitor.
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3.发明申请COMPOSITIONS, KITS AND METHODS FOR SYNTHESIS AND/OR DETECTION OF NUCLEIC ACIDS 审中-公开用于合成和/或检测核酸的组合物，组合物和方法公开(公告)号：US20170002401A1
公开(公告)日：2017-01-05
申请号：US15198689
申请日：2016-06-30
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Christopher TRINH , Tom XU , Yating SHI , Ferrier LE , Claire MARJORIBANKS
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q1/6848 , C12Y207/07007 , C12Q2527/125
Abstract: A composition comprising a thermostable DNA polymerase; and a PCR inhibitor blocking agent, wherein the PCR inhibitor blocking agent is present in an amount effective to enhance tolerance of an assembled PCR to a PCR inhibitor.
Abstract translation: 包含热稳定DNA聚合酶的组合物; 和PCR抑制剂封闭剂，其中所述PCR抑制剂封闭剂以有效增加组装的PCR对PCR抑制剂的耐受性的量存在。
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公开(公告)号：US20180044371A1
公开(公告)日：2018-02-15
申请号：US15682103
申请日：2017-08-21
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Tom XU , Christopher TRINH , Carole BORNARTH , Brian EVANS , Mousumi RATH , Kathy TRAN
CPC classification number: C07H21/02 , C12N15/1006 , C12Q1/6809 , C12Q1/6834 , C12Q1/6876 , C12Q2600/178 , C12Q2525/207 , C12Q2563/149
Abstract: Method and compositions and kits for isolation, identification, and quantification of miRNAs and other small RNAs, including but not limited to, siRNAs, mRNAs, and snRNAs are disclosed. Methods of diagnosing a disease or its progression are also disclosed.
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