Process for preparing a hyaluronic acid fraction having a low polydispersion index
    3.
    发明授权
    Process for preparing a hyaluronic acid fraction having a low polydispersion index 有权
    具有低多分散指数的透明质酸级分的制备方法

    公开(公告)号:US06232303B1

    公开(公告)日:2001-05-15

    申请号:US09426536

    申请日:1999-10-26

    IPC分类号: A61K3170

    CPC分类号: C08B37/0072

    摘要: A process for preparing a hyaluronic acid fraction having an average molecular weight comprised between 5000 and 300,000 and a polydispersion index lower than 1.7, comprising treating the starting high molecular weight hyaluronic acid, contemporaneously with sodium hypochlorite and ultrasounds.

    摘要翻译: 一种制备平均分子量在5000至300,000之间并且多分散指数低于1.7的透明质酸级分的方法,包括用次氯酸钠和超声波同时处理起始高分子量透明质酸。

    Process for preparing a hyaluronic acid fraction having a low
polydispersion index
    5.
    发明授权
    Process for preparing a hyaluronic acid fraction having a low polydispersion index 失效
    具有低多分散指数的透明质酸级分的制备方法

    公开(公告)号:US6020484A

    公开(公告)日:2000-02-01

    申请号:US96646

    申请日:1998-06-12

    IPC分类号: C08B37/08 C07H1/00

    CPC分类号: C08B37/0072

    摘要: A process for preparing a hyaluronic acid fraction having an average molecular weight comprised between 5000 and 300,000 and a polydispersion index lower than 1.7, comprising treating the starting high molecular weight hyaluronic acid, contemporaneously with sodium hypochlorite and ultrasounds.

    摘要翻译: PCT No.PCT / EP96 / 05701 Sec。 371日期:1998年7月12日 102(e)1998年7月12日PCT 1996年12月19日PCT PCT。 公开号WO97 / 22629 日期1997年6月26日制备平均分子量为5000〜300000,多分散指数低于1.7的透明质酸级分的方法,其包括用次氯酸钠和超声波同时处理起始高分子量透明质酸。

    Electrically conductive polymeric biomaterials, the process for their preparation and the use thereof in the biomedical and healthcare field
    10.
    发明授权
    Electrically conductive polymeric biomaterials, the process for their preparation and the use thereof in the biomedical and healthcare field 有权
    导电聚合物生物材料,其制备方法及其在生物医学和保健领域的应用

    公开(公告)号:US07253152B2

    公开(公告)日:2007-08-07

    申请号:US10476854

    申请日:2002-04-29

    IPC分类号: A01N43/04 A61K31/715 C07H1/00

    CPC分类号: A61L27/50 A61L27/48 C08L39/06

    摘要: The present invention concerns the preparation of composite biomaterials constituted by hyaluronic acid and the derivatives thereof in combination with polymers that have electrically conductive properties. In particular, the methods of preparing biomedical devices formed by a two- or three-dimensional polysaccharide matrix and by an electrically conductive membrane. The matrix is constituted by hyaluronic acid derivatives in the form of membranes, woven fabrics, nonwoven felts, meshes, gauzes, guide channels or sponges, while the electrically conductive membrane is constituted by a film of polypyrrole (polymer conductor) in combination with hyaluronic acid or a derivative thereof (doping agent).

    摘要翻译: 本发明涉及由透明质酸及其衍生物与具有导电性质的聚合物组合构成的复合生物材料的制备。 特别是制备由二维或三维多糖基质和导电膜形成的生物医学装置的方法。 该基质由膜,机织织物,非织造毡,网状物,纱布,引导通道或海绵形式的透明质酸衍生物构成,而导电膜由聚吡咯(聚合物导体)与透明质酸组合 或其衍生物(掺杂剂)。