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公开(公告)号:US08932605B2
公开(公告)日:2015-01-13
申请号:US12905584
申请日:2010-10-15
申请人: Langzhou Song , Lynda G. Tussey , Alan R. Shaw , Robert S. Becker , Yi Zhang , Scott W. Umlauf , Ge Liu
发明人: Langzhou Song , Lynda G. Tussey , Alan R. Shaw , Robert S. Becker , Yi Zhang , Scott W. Umlauf , Ge Liu
IPC分类号: A61K39/295 , A61K39/145 , A61K39/00
CPC分类号: A61K39/39 , A61K9/127 , A61K9/5153 , A61K39/00 , A61K39/0005 , A61K39/0275 , A61K39/12 , A61K39/145 , A61K39/155 , A61K39/295 , A61K47/6937 , A61K2039/55516 , A61K2039/55544 , A61K2039/55555 , A61K2039/6031 , A61K2039/6068 , C07K14/005 , C07K14/11 , C07K14/205 , C07K14/21 , C07K14/24 , C07K14/245 , C07K14/255 , C07K14/32 , C07K19/00 , C07K2319/40 , C07K2319/75 , C12N7/00 , C12N2710/20022 , C12N2710/20034 , C12N2710/20071 , C12N2760/16122 , C12N2760/16134 , C12N2760/16162 , C12N2760/16171 , C12N2760/16222 , C12N2760/16234 , C12N2760/16271 , C12N2760/18522 , C12N2760/18534 , C12N2760/18571 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/386 , Y02A50/394 , Y02A50/412
摘要: Compositions that include Toll-like Receptor 5 agonists and at least a portion of at least one viral antigen can be employed in methods that stimulate an immune response in a subject, in particular, a protective immune response in a subject. Compositions can be associated with particles and employed in the methods in relatively low doses to provide protective immunity to viral infection.
摘要翻译: 包括Toll样受体5激动剂和至少一部分至少一种病毒抗原的组合物可以用于刺激受试者中的免疫应答的方法,特别是受试者中的保护性免疫应答。 组合物可以与颗粒相关并且在相对低剂量的方法中使用以提供对病毒感染的保护性免疫。
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公开(公告)号:US20110135680A1
公开(公告)日:2011-06-09
申请号:US12905584
申请日:2010-10-15
申请人: Langzhou Song , Lynda G. Tussey , Alan R. Shaw , Robert S. Becker , Yi Zhang , Scott W. Umlauf , David N. Taylor , Ge Liu , Mark D. Yeager
发明人: Langzhou Song , Lynda G. Tussey , Alan R. Shaw , Robert S. Becker , Yi Zhang , Scott W. Umlauf , David N. Taylor , Ge Liu , Mark D. Yeager
IPC分类号: A61K39/385 , C07K14/195 , C07K19/00 , A61K39/00 , A61P37/04 , B82Y5/00
CPC分类号: A61K39/39 , A61K9/127 , A61K9/5153 , A61K39/00 , A61K39/0005 , A61K39/0275 , A61K39/12 , A61K39/145 , A61K39/155 , A61K39/295 , A61K47/6937 , A61K2039/55516 , A61K2039/55544 , A61K2039/55555 , A61K2039/6031 , A61K2039/6068 , C07K14/005 , C07K14/11 , C07K14/205 , C07K14/21 , C07K14/24 , C07K14/245 , C07K14/255 , C07K14/32 , C07K19/00 , C07K2319/40 , C07K2319/75 , C12N7/00 , C12N2710/20022 , C12N2710/20034 , C12N2710/20071 , C12N2760/16122 , C12N2760/16134 , C12N2760/16162 , C12N2760/16171 , C12N2760/16222 , C12N2760/16234 , C12N2760/16271 , C12N2760/18522 , C12N2760/18534 , C12N2760/18571 , C12N2770/24122 , C12N2770/24134 , C12N2770/24171 , Y02A50/386 , Y02A50/394 , Y02A50/412
摘要: Compositions that include Toll-like Receptor 5 agonists and at least a portion of at least one viral antigen can be employed in methods that stimulate an immune response in a subject, in particular, a protective immune response in a subject. Compositions can be associated with particles and employed in the methods in relatively low doses to provide protective immunity to viral infection.
摘要翻译: 包括Toll样受体5激动剂和至少一部分至少一种病毒抗原的组合物可以用于刺激受试者中的免疫应答的方法,特别是受试者中的保护性免疫应答。 组合物可以与颗粒相关并且在相对低剂量的方法中使用以提供对病毒感染的保护性免疫。
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