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    Medical Device Fabrication Process Including Strain Induced Crystallization With Enhanced Crystallization
    3.
    发明申请
    Medical Device Fabrication Process Including Strain Induced Crystallization With Enhanced Crystallization 有权
    包括具有增强结晶的应变诱导结晶的医疗器械制造工艺

    公开(公告)号：US20110215505A1

    公开(公告)日：2011-09-08

    申请号：US13077635

    申请日：2011-03-31

    申请人： Lothar W. Kleiner ,  Fuh-Wei Tang

    发明人： Lothar W. Kleiner ,  Fuh-Wei Tang

    IPC分类号： B29C71/02

    CPC分类号： B29C35/16 ,  B29C45/0055 ,  B29C47/0038 ,  B29C71/02 ,  B29L2031/7534

    摘要： Methods of fabricating a polymeric implantable device, such as a stent, with improved fracture toughness through annealing a polymer construct below the glass transition temperature of the polymer of the construct prior to a deformation step are disclosed herein. The deformation of the construct induces crystallization in the polymer construct through strain-induced crystallization. The annealing of the polymer construct accelerates the crystallization induced during the deformation and results in an increase in crystallite density with smaller crystallites as compared to deformation of a tube that has not been annealed. A stent scaffolding is then made from the deformed tube.

    摘要翻译： 本文公开了通过在变形步骤之前将构建体的聚合物的玻璃化转变温度退火到低于聚合物的玻璃化转变温度来制备具有改进的断裂韧性的聚合物可植入装置（例如支架）的方法。 构建体的变形通过应变诱导结晶在聚合物构造体中诱导结晶。 聚合物构件的退火加速了在变形期间引起的结晶，并且与没有退火的管的变形相比，结晶晶体密度随着较小晶粒的增加而增加。 然后从变形管制成支架式支架。

    Medical device fabrication process including strain induced crystallization with enhanced crystallization
    4.
    发明授权
    Medical device fabrication process including strain induced crystallization with enhanced crystallization 有权
    医疗器械制造工艺包括应变诱导结晶，增强结晶

    公开(公告)号：US08765040B2

    公开(公告)日：2014-07-01

    申请号：US13077635

    申请日：2011-03-31

    申请人： Lothar W. Kleiner ,  Fuh-Wei Tang

    发明人： Lothar W. Kleiner ,  Fuh-Wei Tang

    IPC分类号： B29C49/00 ,  B29C35/02 ,  B29C35/16

    CPC分类号： B29C35/16 ,  B29C45/0055 ,  B29C47/0038 ,  B29C71/02 ,  B29L2031/7534

    摘要： Methods of fabricating a polymeric implantable device, such as a stent, with improved fracture toughness through annealing a polymer construct below the glass transition temperature of the polymer of the construct prior to a deformation step are disclosed herein. The deformation of the construct induces crystallization in the polymer construct through strain-induced crystallization. The annealing of the polymer construct accelerates the crystallization induced during the deformation and results in an increase in crystallite density with smaller crystallites as compared to deformation of a tube that has not been annealed. A stent scaffolding is then made from the deformed tube.

    摘要翻译： 本文公开了通过在变形步骤之前将构建体的聚合物的玻璃化转变温度退火到低于聚合物的玻璃化转变温度来制备具有改进的断裂韧性的聚合物可植入装置（例如支架）的方法。 构建体的变形通过应变诱导结晶在聚合物构造体中诱导结晶。 聚合物构件的退火加速了在变形期间引起的结晶，并且与没有退火的管的变形相比，结晶晶体密度随着较小晶粒的增加而增加。 然后从变形管制成支架式支架。

    Stabilizing Semi-Crystalline Polymers To Improve Storage Performance Of Medical Devices
    7.
    发明申请
    Stabilizing Semi-Crystalline Polymers To Improve Storage Performance Of Medical Devices 审中-公开
    稳定半结晶聚合物改善医疗器械的储存性能

    公开(公告)号：US20110260352A1

    公开(公告)日：2011-10-27

    申请号：US12764803

    申请日：2010-04-21

    申请人： Fuh-Wei Tang ,  James Oberhauser ,  Manish Gada ,  Lothar W. Kleiner ,  Vincent J. Gueriguian

    发明人： Fuh-Wei Tang ,  James Oberhauser ,  Manish Gada ,  Lothar W. Kleiner ,  Vincent J. Gueriguian

    IPC分类号： B29C44/20

    CPC分类号： B29C71/02 ,  A61F2/82 ,  B29C2071/022

    摘要： Methods are disclosed for improving the storage performance of polymeric stents that reduce or eliminate the effects of long term aging on the properties of the stents. A polymeric stent or a polymeric tube from which a stent is made is heated to a temperature between ambient and the glass transition temperature of the polymer for a period of time. The heating causes densification or an increase in density of the polymer which stabilizes the properties of the polymer in later processing steps and storage. The stent can be made from a polymeric tube that is expanded at a temperature above the glass transition temperature and cooled to maintain an expanded diameter.

    摘要翻译： 公开了用于改善聚合物支架的储存性能的方法，其减少或消除长期老化对支架性质的影响。 制成支架的聚合物支架或聚合物管被加热到环境温度和聚合物的玻璃化转变温度一段时间之间的温度。 加热导致聚合物的致密化或密度增加，其在稍后的处理步骤和储存中稳定聚合物的性质。 支架可以由在高于玻璃化转变温度的温度下膨胀的聚合物管制成，并被冷却以保持扩张的直径。