-
公开(公告)号：US20080113896A1
公开(公告)日：2008-05-15
申请号：US11793390
申请日：2005-12-21
CPC分类号： C12P21/06 , A23J3/344 , A23L33/11 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K38/00 , A23V2200/3262 , A23V2200/332 , A23V2200/326 , A23V2250/54246 , A23V2250/2136 , A23V2250/7052 , A23V2250/706 , A23V2250/7056
摘要： A process to produce IPP and VPP from a protein source that comprises the -I-P-P- and -V-P-P- sequence in its protein sequence and whereby at least 40% of -I-P-P- sequence present in the protein source is converted into the peptide IPP and at least 40% of the -V-P-P- sequence present in the protein source is converted into the peptide VPP, which comprises the use of a proline specific endoprotease and an amino-peptidase preferably in a single enzymatic step.
摘要翻译： 从其蛋白质序列中包含-IPP-和-VPP-序列的蛋白质源产生IPP和VPP的过程，并且其中存在于蛋白质源中的-IPP-序列的至少40％被转化为肽IPP，并且在 存在于蛋白质源中的-VPP序列的至少40％被转化为肽VPP，其包括优选在单个酶促步骤中使用脯氨酸特异性内切蛋白酶和氨基肽酶。
-
公开(公告)号：US07879804B2
公开(公告)日：2011-02-01
申请号：US11793390
申请日：2005-12-21
IPC分类号： A61K38/06
CPC分类号： C12P21/06 , A23J3/344 , A23L33/11 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K38/00 , A23V2200/3262 , A23V2200/332 , A23V2200/326 , A23V2250/54246 , A23V2250/2136 , A23V2250/7052 , A23V2250/706 , A23V2250/7056
摘要： A process to produce IPP and VPP from a protein source that comprises the -I-P-P- and -V-P-P- sequence in its protein sequence and whereby at least 40% of -I-P-P- sequence present in the protein source is converted into the peptide IPP and at least 40% of the -V-P-P- sequence present in the protein source is converted into the peptide VPP, which comprises the use of a proline specific endoprotease and an amino-peptidase preferably in a single enzymatic step.
摘要翻译： 从其蛋白质序列中包含-IPP-和-VPP-序列的蛋白质源产生IPP和VPP的过程，并且其中存在于蛋白质源中的-IPP-序列的至少40％被转化为肽IPP，并且在 存在于蛋白质源中的-VPP序列的至少40％被转化为肽VPP，其包括优选在单个酶促步骤中使用脯氨酸特异性内切蛋白酶和氨基肽酶。
-
公开(公告)号：US20070207944A1
公开(公告)日：2007-09-06
申请号：US11631951
申请日：2005-07-12
申请人： Luppo Edens , Andre Leonardus De Roos , Robertus Antonius Mijndert Van Der Hoeven , Philippus Antonius Deen
发明人： Luppo Edens , Andre Leonardus De Roos , Robertus Antonius Mijndert Van Der Hoeven , Philippus Antonius Deen
摘要： The present invention describes a process to produce IPP from a protein source whereby the ratio of IPP and VPP produced from the protein is at least 5, preferably at least 10 and more preferably at least 20, which comprises the use of a proline specific endoprotease.
摘要翻译： 本发明描述了从蛋白质源产生IPP的方法，其中由蛋白质产生的IPP和VPP的比例为至少5，优选至少10，更优选至少为20，其包括使用脯氨酸特异性内切蛋白酶。
-
公开(公告)号：US20050175622A1
公开(公告)日：2005-08-11
申请号：US10483948
申请日：2002-07-18
申请人： Luppo Edens , Andre De Roos
发明人： Luppo Edens , Andre De Roos
IPC分类号： A23K1/16 , A23J3/10 , A23J3/34 , A23L1/30 , A23L1/305 , A23L2/52 , A23L2/66 , A61K39/00 , A61K39/38
摘要： The present invention provides a composition comprising hydrolysed milk casein and, preferably non-hydrolysed whey protein in a ratio from 9:1 to 1:1 (on dry weight), which is a clear liquid at pH 4 when dissolved or present in water in an amount of 40 g/litre at 10° C.
摘要翻译： 本发明提供了一种组合物，其包含水解乳酪蛋白和优选非水解乳清蛋白，其比例为9:1至1:1（干重），其在溶于或存在于水中时为pH4时的澄清液体 在10℃下的量为40g / l
-
5.发明授权公开(公告)号：US08802088B2
公开(公告)日：2014-08-12
申请号：US12989869
申请日：2009-04-27
IPC分类号： A61K38/48 , C12Q1/34 , C12Q1/37 , A61K38/01 , A61K38/05 , A61K38/06 , A61K38/00 , C07K14/00 , C07K16/02 , A61K47/34 , C12Q1/06 , G01N33/68 , A61K38/47 , A61K38/02 , A61P25/00
CPC分类号： A61K38/47 , A23J3/341 , A23L33/18 , A61K31/405 , C12P21/06 , C12Y302/01017
摘要： The present invention relates to a composition which comprises tryptophan whereby 10 to 90%, preferably 20 to 80% of the tryptophan is present as free tryptophan or peptide-bound tryptophan and 10 to 90%, preferably 20 to 80% of the tryptophan is present as polypeptide-bound tryptophan.
摘要翻译： 本发明涉及一种组合物，其包含色氨酸，由此存在色氨酸的10至90％，优选20至80％的游离色氨酸或肽结合的色氨酸，并且存在10至90％，优选20至80％的色氨酸存在 作为多肽结合的色氨酸。
-
公开(公告)号：US07323327B2
公开(公告)日：2008-01-29
申请号：US10469204
申请日：2002-02-22
申请人： Luppo Edens , Albertus Van Dijk , Philipp Krubasik , Kaj Albermann , Alexander Stock , Erik Kimpel , Sabine Klugbauer , Christian Wagner , Andreas Fritz , Wilk Von Gustedt , Oliver Heinrich , Dieter Maier , Fabio Spreafico , Ulrike Folkers , Sylvia Hopper , Wolfram Kemmner , Pamela Tan , Josephine Stiebler , Richard Albang
发明人： Luppo Edens , Albertus Van Dijk , Philipp Krubasik , Kaj Albermann , Alexander Stock , Erik Kimpel , Sabine Klugbauer , Christian Wagner , Andreas Fritz , Wilk Von Gustedt , Oliver Heinrich , Dieter Maier , Fabio Spreafico , Ulrike Folkers , Sylvia Hopper , Wolfram Kemmner , Pamela Tan , Josephine Stiebler , Richard Albang
CPC分类号： A23J3/16 , A23J3/343 , A23J3/344 , A23J3/346 , A23L2/02 , A23L2/84 , A23L33/18 , A23L33/40 , C07K2319/00 , C12H1/003 , C12N9/62 , C12Q1/37 , G01N33/56961 , G01N33/573 , G01N2333/38
摘要： The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
摘要翻译： 本发明涉及新鉴定的编码从黑曲霉获得的新型蛋白酶的基因序列。 本发明的特征在于新基因的全长基因序列，其cDNA序列以及全长功能蛋白及其片段。 本发明还涉及在工业过程中使用这些酶的方法和诊断真菌感染的方法。 本发明还包括用根据本发明的DNA转化的细胞和其中根据本发明的蛋白酶被遗传修饰以增强或降低其活性和/或表达水平的细胞。
-
公开(公告)号：US20050064403A1
公开(公告)日：2005-03-24
申请号：US10469204
申请日：2002-02-22
申请人： Luppo Edens , Dijk Alard , Philipp Krubasik , Kaj Albermann , Stock Alexander , Erik Kimpel , Sabine Klugbauer , Christian Wagner , Andreas Fritz , Gustedt Wilk , Oliver Heinrich , Dieter Maier , Fabio Spreafico , Ulrike Folkers , Sylvia Hopper , Wolfram Kemmner , Pamela Tan , Josephine Stiebler , Richard Albang
发明人： Luppo Edens , Dijk Alard , Philipp Krubasik , Kaj Albermann , Stock Alexander , Erik Kimpel , Sabine Klugbauer , Christian Wagner , Andreas Fritz , Gustedt Wilk , Oliver Heinrich , Dieter Maier , Fabio Spreafico , Ulrike Folkers , Sylvia Hopper , Wolfram Kemmner , Pamela Tan , Josephine Stiebler , Richard Albang
IPC分类号： A23J3/16 , A23J3/34 , A23L1/29 , A23L1/305 , A23L2/02 , A23L2/84 , C07K16/40 , C12H1/00 , C12N9/62 , C12N15/57 , C12N15/63 , C12Q1/37 , G01N33/569 , G01N33/573 , C12Q1/68 , C07H21/04 , C12N9/64
CPC分类号： A23J3/16 , A23J3/343 , A23J3/344 , A23J3/346 , A23L2/02 , A23L2/84 , A23L33/18 , A23L33/40 , C07K2319/00 , C12H1/003 , C12N9/62 , C12Q1/37 , G01N33/56961 , G01N33/573 , G01N2333/38
摘要： The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
摘要翻译： 本发明涉及新鉴定的编码从黑曲霉获得的新型蛋白酶的基因序列。 本发明的特征在于新基因的全长基因序列，其cDNA序列以及全长功能蛋白及其片段。 本发明还涉及在工业过程中使用这些酶的方法和诊断真菌感染的方法。 本发明还包括用根据本发明的DNA转化的细胞和其中根据本发明的蛋白酶被遗传修饰以增强或降低其活性和/或表达水平的细胞。
-
公开(公告)号：US06368595B2
公开(公告)日：2002-04-09
申请号：US09380805
申请日：1999-10-25
申请人： Luppo Edens , Bertus Noordam
发明人： Luppo Edens , Bertus Noordam
IPC分类号： A61K3846
CPC分类号： A61K8/0208 , A61K8/66 , A61K8/8129 , A61K9/7007 , A61Q7/02 , A61Q19/00 , A61Q19/08 , A61Q19/10
摘要： The present invention discloses a method for topical application of an enzyme, wherein the enzyme becomes incorporated in a peelable film, for instance a polyvinyl alcohol film, after its application. In this way, the release of enzyme-containing dust particles from the site of application is prevented.
摘要翻译： 本发明公开了一种局部施用酶的方法，其中在施用之后将酶并入可剥离膜，例如聚乙烯醇膜中。 以这种方式，防止了从施用部位释放含酶粉尘颗粒。
-
9.发明授权DNA sequences encoding the various allelic forms of mature thaumatin, and cloning vehicles, etc. 失效编码成熟的马蹄拟糖的各种等位基因形式的DNA序列和克隆载体等
公开(公告)号：US4891316A
公开(公告)日：1990-01-02
申请号：US742139
申请日：1985-06-07
IPC分类号： C12N15/09 , C07H21/04 , C07K14/43 , C12N1/20 , C12N1/21 , C12N15/31 , C12N15/66 , C12N15/70 , C12P19/34 , C12P21/00 , C12P21/02 , C12R1/19
摘要： The invention relates to DNA sequences encoding the various allelic forms of mature thaumatin, and cloning vehicles comprising said DNA sequences and their use in transforming microorganisms.
摘要翻译： 本发明涉及编码成熟的马蹄拟糖的各种等位基因形式的DNA序列，以及包含所述DNA序列的克隆载体及其在转化微生物中的用途。
-
10.发明授权公开(公告)号：US08524225B2
公开(公告)日：2013-09-03
申请号：US10572811
申请日：2004-09-23
申请人： Luppo Edens , Melissa Harvey , Robertus Antonius Mijndert Van Der Hoeven , Andre Leonardus De Roos
发明人： Luppo Edens , Melissa Harvey , Robertus Antonius Mijndert Van Der Hoeven , Andre Leonardus De Roos
IPC分类号： A61K38/48
CPC分类号： C12P21/06 , A23J3/346 , A61K38/482
摘要： The present invention relates to a process for the proteolytic hydrolysis of a peptide or a polypeptide, said peptide or polypeptide comprising 4 to 40, preferably 5 to 35, amino acid residues and said peptide or polypeptide is not hydrolysable by subtilisin whereby said peptide or polypeptide is hydrolysed by a proline specific endo protease at a pH of 6.5 or lower, preferably 5.5 or lower and more preferably 5.0 or lower to hydrolyse said peptide or polypeptide.
摘要翻译： 本发明涉及肽或多肽的蛋白水解水解方法，所述肽或多肽包含4至40个，优选5至35个氨基酸残基，并且所述肽或多肽不能被枯草杆菌蛋白酶水解，因此所述肽或多肽 由pH6.5或更低，优选5.5或更低，更优选5.0或更低的脯氨酸特异性内切蛋白酶水解，以水解所述肽或多肽。
-
-
-
-
-
-
-
-
-
搜索结果
67 条记录 (耗时 0.029 秒)
