公开(公告)号：US20070299434A1

公开(公告)日：2007-12-27

申请号：US11894467

申请日：2007-08-20

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

IPC分类号： A61B18/18

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗卵圆孔卵泡（PFO）的方法和装置提供用导管装置向邻近PFO的组织施加能量，以基本上封闭PFO。 装置通常包括导管装置，其具有在其远端处或其近端处的至少一个能量传递构件，其被配置为向PFO组织施加能量以急剧，基本上关闭PFO。 施加的能量可以是单极性或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热等。 导管装置的一些实施例还包括靠近远端的一个或多个组织定位构件，用于帮助使PFO组织在一起，例如PFO覆盖构件，真空施加构件等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US20070213748A1

公开(公告)日：2007-09-13

申请号：US11801450

申请日：2007-05-10

申请人： Mark Deem ,  Douglas Sutton ,  Hanson Gifford ,  Bernard Andreas ,  Ronald French

发明人： Mark Deem ,  Douglas Sutton ,  Hanson Gifford ,  Bernard Andreas ,  Ronald French

IPC分类号： A61B17/00

CPC分类号： A61B17/1114 ,  A61B17/00234 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/122 ,  A61B2017/00557 ,  A61B2017/306 ,  A61B2090/395 ,  A61F5/0083 ,  A61F5/0086

摘要： Various obesity treatment tools and methods are described herein, as well as treatments for other gastric-related diseases, e.g., GERD. Treatment includes reducing the size of the stomach pouch to limit the caloric intake as well as to provide an earlier feeling of satiety. This may be done by creating a smaller gastric pouch within the stomach directly from the interior of the stomach itself. The smaller pouches may be made through the use of individual anchoring devices, rotating probes, or volume reduction devices. A pyloroplasty procedure may also be performed to render the pyloric sphincter incompetent. A gastric bypass procedure may additionally be performed using atraumatic magnetic anastomoses devices so that sugars and fats are passed directly to the bowel while bypassing the stomach. Many of these procedures may be done in a variety of combinations. Treatment may create enforced behavioral modifications by discouraging the ingestion of high-caloric foods

公开(公告)号：US20070191863A1

公开(公告)日：2007-08-16

申请号：US11615810

申请日：2006-12-22

申请人： Eugene De Juan ,  Stephen Boyd ,  Mark Deem ,  Hanson Gifford ,  Dan Rosenman

发明人： Eugene De Juan ,  Stephen Boyd ,  Mark Deem ,  Hanson Gifford ,  Dan Rosenman

IPC分类号： A61F11/00

CPC分类号： A61F9/00781 ,  A61B34/70 ,  A61B90/00 ,  A61F2/14 ,  A61F2/142 ,  A61F9/0008 ,  A61F9/0017 ,  A61F9/007 ,  A61F9/00736 ,  A61F9/0133 ,  A61F11/00 ,  A61F2250/0001 ,  A61F2250/0096 ,  A61F2250/0097 ,  A61K9/0051 ,  A61M27/002 ,  A61M2202/04 ,  A61M2210/0612

摘要： Methods and devices are adapted for implanting into the eye. An incision is formed in the cornea of the eye and a shunt is inserted through the incision into the anterior chamber of the eye. The shunt includes a fluid passageway. The shunt is passed along a pathway from the anterior chamber through the scleral spur of the eye into the suprachoroidal space and positioned in a first position such that a first portion of the fluid passageway communicates with the anterior chamber and a second portion of the fluid passageway communicates with the suprachoroidal space to provide a fluid passageway between the suprachoroidal space and the anterior chamber.

摘要翻译： 方法和装置适于植入眼睛。 在眼睛的角膜中形成切口，并且通过切口将分路插入眼睛的前房。 分流器包括流体通道。 所述分流器沿着从所述前房通过所述眼睛的巩膜刺入所述脉管外空间的路径通过并且定位在第一位置，使得所述流体通道的第一部分与所述前房连通，并且所述流体通道的第二部分 与脉管外空间连通，以在脉络膜上空间和前房之间提供流体通道。

公开(公告)号：US20070118159A1

公开(公告)日：2007-05-24

申请号：US11654783

申请日：2007-01-18

申请人： Mark Deem ,  Douglas Sutton ,  Hanson Gifford ,  Bernard Andreas ,  Ronald French

发明人： Mark Deem ,  Douglas Sutton ,  Hanson Gifford ,  Bernard Andreas ,  Ronald French

IPC分类号： A61B17/08 ,  A61B17/10

CPC分类号： A61B17/1114 ,  A61B17/00234 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/122 ,  A61B2017/00557 ,  A61B2017/306 ,  A61B2090/395 ,  A61F5/0083 ,  A61F5/0086

摘要： Various obesity treatment tools and methods are described herein, as well as treatments for other gastric-related diseases, e.g., GERD. Treatment includes reducing the size of the stomach pouch to limit the caloric intake as well as to provide an earlier feeling of satiety. This may be done by creating a smaller gastric pouch within the stomach directly from the interior of the stomach itself. The smaller pouches may be made through the use of individual anchoring devices, rotating probes, or volume reduction devices. A pyloroplasty procedure may also be performed to render the pyloric sphincter incompetent. A gastric bypass procedure may additionally be performed using atraumatic magnetic anastomoses devices so that sugars and fats are passed directly to the bowel while bypassing the stomach. Many of these procedures may be done in a variety of combinations. Treatment may create enforced behavioral modifications by discouraging the ingestion of high-caloric foods.

公开(公告)号：US20070112347A1

公开(公告)日：2007-05-17

申请号：US11622194

申请日：2007-01-11

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

IPC分类号： A61B18/18

CPC分类号： A61B18/1492 ,  A61B18/1445 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods, devices and systems for treating patent foramen ovale (PFO) involve advancing a catheter device to a position in a heart for treating a PFO, bringing tissues adjacent the PFO at least partially together, and applying energy to the tissues to substantially close the PFO acutely. Catheter devices generally include an elongate catheter body, at least one tissue apposition member at or near the distal end for bringing the tissues together, and at least one energy transmission member at or near the distal end for applying energy to the tissues. In some embodiments, the tissue apposition member(s) also act as the energy transmission member(s). Applied energy may be monoploar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like.

摘要翻译： 用于治疗卵孔卵泡（PFO）的方法，装置和系统涉及将导管装置推进到心脏中的位置以治疗PFO，使与PFO相邻的组织至少部分地在一起，并且向组织施加能量以基本上封闭PFO 急剧地 导管装置通常包括细长导管主体，位于或靠近远端的至少一个组织定位构件，用于将组织带到一起，以及在远端处或附近的至少一个能量传递构件，用于向组织施加能量。 在一些实施例中，组织安置构件也用作能量传递构件。 应用能量可以是单极或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热等。

公开(公告)号：US20060276846A1

公开(公告)日：2006-12-07

申请号：US11506230

申请日：2006-08-17

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

IPC分类号： A61N1/00

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US20060276779A1

公开(公告)日：2006-12-07

申请号：US11464755

申请日：2006-08-15

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark Deem ,  Hanson Gifford ,  Jose Alejandro

IPC分类号： A61B18/04

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monoploar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗卵圆孔卵泡（PFO）的方法和装置提供用导管装置向邻近PFO的组织施加能量，以基本上封闭PFO。 装置通常包括导管装置，其具有在其远端处或其近端处的至少一个能量传递构件，其被配置为向PFO组织施加能量以急剧，基本上关闭PFO。 应用能量可以是单极或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热等。 导管装置的一些实施例还包括靠近远端的一个或多个组织定位构件，用于帮助使PFO组织在一起，例如PFO覆盖构件，真空施加构件等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US20060229659A1

公开(公告)日：2006-10-12

申请号：US11299246

申请日：2005-12-09

申请人： Hanson Gifford ,  Mark Deem ,  Stephen Boyd

发明人： Hanson Gifford ,  Mark Deem ,  Stephen Boyd

IPC分类号： A61M29/00

CPC分类号： A61B18/1492 ,  A61B8/12 ,  A61B17/22012 ,  A61B17/2202 ,  A61B17/221 ,  A61B17/320758 ,  A61B18/02 ,  A61B18/18 ,  A61B2017/22038 ,  A61B2017/22061 ,  A61B2017/22069 ,  A61B2017/22079 ,  A61B2017/22098 ,  A61B2017/2215 ,  A61B2018/00011 ,  A61B2018/0022 ,  A61B2018/0262 ,  A61F2/2445 ,  A61M25/04 ,  A61M2025/105 ,  A61N7/022 ,  A61N2007/0039

摘要： The present invention provides devices and methods for decalcifying an aortic valve. The methods and devices of the present invention break up or obliterate calcific deposits in and around the aortic valve through application or removal of heat energy from the calcific deposits.

摘要翻译： 本发明提供了用于脱钙主动脉瓣的装置和方法。 本发明的方法和装置通过从钙化沉积物中施加或去除热能来分解或消除主动脉瓣内和周围的钙沉积物。

公开(公告)号：US20060225742A1

公开(公告)日：2006-10-12

申请号：US11446043

申请日：2006-06-01

申请人： Mark Deem ,  Hanson Gifford

发明人： Mark Deem ,  Hanson Gifford

IPC分类号： A62B9/06

CPC分类号： A61M5/162 ,  A61B1/018 ,  A61B1/04 ,  A61B1/0661 ,  A61B1/2676 ,  A61M5/1452 ,  A61M5/30 ,  A61M11/00 ,  A61M16/00 ,  A61M25/0084 ,  A61M25/10 ,  A61M2025/0086 ,  A61M2025/105 ,  A61M2202/049 ,  A61M2210/1035

摘要： Apparatus for providing intrabronchial delivery of neurotoxins to control the effects of asthma comprises a shaft having proximal and distal ends and a neurotoxin applicator assembly disposed on the distal end. The neurotoxin applicator assembly comprises a deployable needle assembly, a rotating needle assembly, and a needle-less injection assembly or a nebulizer assembly.

公开(公告)号：US20050261672A1

公开(公告)日：2005-11-24

申请号：US11133088

申请日：2005-05-18

申请人： Mark Deem ,  Hanson Gifford ,  Denise Demarais

发明人： Mark Deem ,  Hanson Gifford ,  Denise Demarais

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/00613

摘要： Methods and apparatus are provided for selective denervation of conduction pathways in the heart for the treatment of dysrhythmias, including one or more ablation or electroporation catheters having electrodes for stimulating, targeting, and ablating fat pad tissue and other cardiac tissue to selectively denervate heart tissue.

摘要翻译： 提供了用于选择性去神经支配心脏传导途径用于治疗心律失常的方法和装置，包括一个或多个消融或电穿孔导管，其具有用于刺激，靶向和消融脂肪垫组织和其它心脏组织以选择性去神经细胞组织的电极。