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    Nucleotide sequences which code for the ACP gene
    4.
    发明授权
    Nucleotide sequences which code for the ACP gene 失效
    编码ACP基因的核苷酸序列

    公开(公告)号：US06830921B2

    公开(公告)日：2004-12-14

    申请号：US09852137

    申请日：2001-05-10

    申请人： Bettina Möckel ,  Anke Weissenborn ,  Walter Pfefferle ,  Hermann Sahm ,  Lothar Eggeling ,  Madhavan Nampoothiri

    发明人： Bettina Möckel ,  Anke Weissenborn ,  Walter Pfefferle ,  Hermann Sahm ,  Lothar Eggeling ,  Madhavan Nampoothiri

    IPC分类号： C12N120

    CPC分类号： C12P13/08 ,  C07K14/34

    摘要： The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70 % to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70 % to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), a process for the fermentative preparation of L-amino acids with enhancement of the acp gene and the use of the polynucleotide as a primer or hybridization probe.

    摘要翻译： 本发明涉及一种分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸 b）编码多肽的多核苷酸，其包含与SEQ ID No.2的氨基酸序列至少70％相同的氨基酸序列，c）与a）的多核苷酸互补的多核苷酸， 或b），和d）多核苷酸，其包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸，具有增强的acp基因的L-氨基酸的发酵制备方法和所述多核苷酸的用途 作为引物或杂交探针。

    Method For the Fermentative Production of L-Valine and Suitable Microorganism
    8.
    发明申请
    Method For the Fermentative Production of L-Valine and Suitable Microorganism 失效
    L-缬氨酸和合适的微生物发酵生产方法

    公开(公告)号：US20080153139A1

    公开(公告)日：2008-06-26

    申请号：US11663984

    申请日：2006-04-06

    申请人： Jan Marienhagen ,  Lothar Eggeling ,  Hermann Sahm

    发明人： Jan Marienhagen ,  Lothar Eggeling ,  Hermann Sahm

    IPC分类号： C12P13/08 ,  C12N1/21

    CPC分类号： C12P13/08 ,  C12N9/1096

    摘要： The invention relates to a method for producing L-valine and to a suitable microorganism. The inventive method is characterized by preferably enhancing the transaminase C activity of a coryneform bacterium, especially Corynebacteriuim glutamicum. The organisms so modified have a yield in L-valine which is 35.8% higher than that of non-modified organisms.

    摘要翻译： 本发明涉及L-缬氨酸和合适微生物的生产方法。 本发明的方法的特征在于优选增强棒状细菌，特别是谷氨酸棒杆菌（Corynebacteriuim glutamicum）的转氨酶C活性。 如此修饰的生物体在L-缬氨酸中的产率高于非改性生物体的35.8％。