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公开(公告)号:US20090011108A1
公开(公告)日:2009-01-08
申请号:US11911249
申请日:2006-04-25
申请人: Shizuka Kogiso , Makoto Ozeki , Nobuyuki Aoi
发明人: Shizuka Kogiso , Makoto Ozeki , Nobuyuki Aoi
CPC分类号: A61K47/22 , A23L2/52 , A23L2/60 , A23L2/66 , A23L27/70 , A23L33/10 , A23L33/175 , A23L33/18 , A23L33/185 , A23V2002/00 , A61K31/195
摘要: Providing a hydrated food which contains theanine and in which theanine content can stably be maintained even when the hydrated food is preserved for a long period of time and the taste threshold of the food can be improved and the peculiar taste can be flavored. The problem can be overcome by a hydrated food containing theanine and pyroglutamic acid. In this case, it is preferable that pH ranges from about 2.8 to about 7.5. Furthermore, it is preferable that a content of pyroglutamic acid ranges from about 1% to about 20% relative to a content of theanine.
摘要翻译: 提供含有茶氨酸的水合食物,即使长时间保持水合食物也能够稳定地维持茶氨酸含量,并且可以提高食品的味道阈值,并且可以调味特有的味道。 这个问题可以通过含有茶氨酸和焦谷氨酸的水合食物来克服。 在这种情况下,优选pH为约2.8至约7.5。 此外,相对于茶氨酸的含量,焦谷氨酸的含量优选为约1%〜约20%。
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公开(公告)号:US20070224667A1
公开(公告)日:2007-09-27
申请号:US11571074
申请日:2005-06-22
申请人: Yukitaka Okada , Makoto Ozeki , Nobuyuki Aoi
发明人: Yukitaka Okada , Makoto Ozeki , Nobuyuki Aoi
IPC分类号: C12P13/04
摘要: In a method of making theanine, glutaminase is derived from microbes of one or more of Bacillus, mold and yeast is caused to act on glutamine and ethylamine derivative.
摘要翻译: 在制备茶氨酸的方法中,谷氨酰胺酶衍生自芽孢杆菌属中的一种或多种的微生物,使霉菌和酵母作用于谷氨酰胺和乙胺衍生物。
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公开(公告)号:US20060045905A1
公开(公告)日:2006-03-02
申请号:US11209126
申请日:2005-08-22
申请人: Makoto Ozeki , Nobuyuki Aoi
发明人: Makoto Ozeki , Nobuyuki Aoi
IPC分类号: A61K31/522 , A61K47/00
CPC分类号: A61K31/522 , A23L2/02 , A23L2/52 , A23L33/105 , A61K9/0056 , A61K9/2018
摘要: A composition for repressing transformation growth factor β contains theanine as an active substance. The composition is useful for preventing or treating chronic glomerulonephritis, renal interstitial fibrosis, hepatic fibrosis, hepatic cirrhosis, idiopathic interstitial pneumonia, keloid, hidebound disease, arterial sclerosis, myocardial infarction, cardiac fibrosis, restenosis, acute megakaryoblastic leukemia, adult T-cell leukemia, chronic fatigue syndrome or ordinary fatigue.
摘要翻译: 用于抑制转化生长因子β的组合物含有作为活性物质的茶氨酸。 该组合物可用于预防或治疗慢性肾小球肾炎,肾间质性纤维化,肝纤维化,肝硬化,特发性间质性肺炎,瘢痕疙瘩,隐匿性疾病,动脉硬化,心肌梗死,心脏纤维化,再狭窄,急性巨核细胞白血病,成人T细胞白血病 ,慢性疲劳综合征或普通疲劳。
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公开(公告)号:US08211674B2
公开(公告)日:2012-07-03
申请号:US11571074
申请日:2005-06-22
申请人: Yukitaka Okada , Makoto Ozeki , Nobuyuki Aoi
发明人: Yukitaka Okada , Makoto Ozeki , Nobuyuki Aoi
IPC分类号: C12P13/14
摘要: In a method of making theanine, glutaminase is derived from microbes of one or more of Bacillus, mold and yeast is caused to act on glutamine and ethylamine derivative.
摘要翻译: 在制备茶氨酸的方法中,谷氨酰胺酶衍生自芽孢杆菌属中的一种或多种的微生物,使霉菌和酵母作用于谷氨酰胺和乙胺衍生物。
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公开(公告)号:US10519182B2
公开(公告)日:2019-12-31
申请号:US16097120
申请日:2018-01-31
申请人: Masamitsu Moriwaki , Kentaro Kumoi , Makoto Ozeki
发明人: Masamitsu Moriwaki , Kentaro Kumoi , Makoto Ozeki
IPC分类号: C07H17/07 , A23L3/3499 , A61K47/40 , A61K8/60 , A61K8/73 , A61K31/7048 , A23F3/16 , A23L2/02 , A23L2/44 , A23L21/10 , A23F5/24
摘要: A method for producing a flavonoid inclusion compound, including a cleaving step including treating a sparingly soluble flavonoid having a rhamnoside structure with an enzyme having a rhamnosidase activity in the presence of a cyclodextrin to cleave a rhamnose. According to the production method of the present invention, a flavonoid inclusion compound and a composition of flavonoid glycosides having excellent solubility in water can be efficiently produced, so that the compound and composition can be suitably utilized in the fields of medicaments, foodstuff, health foods, foods for specified health use, cosmetics, and the like.
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公开(公告)号:US20080039526A1
公开(公告)日:2008-02-14
申请号:US11843913
申请日:2007-08-23
申请人: Makoto Ozeki , Haruo Yao , Tsutomu Okubo , Lekh Juneja
发明人: Makoto Ozeki , Haruo Yao , Tsutomu Okubo , Lekh Juneja
IPC分类号: A61K31/195 , A61P25/20
CPC分类号: A23G1/30 , A23G1/48 , A23G3/36 , A23G3/48 , A23G4/06 , A23G4/068 , A23L33/105 , A23L33/17 , A61K31/198
摘要: An object of the present invention is to provide a composition for promoting sleep, which any one can safely take on a daily basis without any risks of adverse action. In addition, an object of the present invention is to provide food and a medicament, comprising the above-mentioned composition, having an effect for promoting sleep for an individual having sleep disorders. Further, an object of the present invention is to provide a method for promoting sleep comprising administering theanine to an individual having sleep disorders, and use of theanine for preparation of the food or medicament for an individual having sleep disorders.
摘要翻译: 本发明的目的是提供一种用于促进睡眠的组合物,任何人可以每天安全地服用,而没有不利的作用的风险。 此外,本发明的目的是提供包含上述组合物的食物和药物,其具有促进具有睡眠障碍的个体的睡眠的效果。 此外,本发明的目的是提供一种促进睡眠的方法,其包括向具有睡眠障碍的个体施用茶氨酸,以及使用茶氨酸来制备具有睡眠障碍的个体的食物或药物。
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公开(公告)号:US07273621B2
公开(公告)日:2007-09-25
申请号:US09980620
申请日:2001-04-04
申请人: Makoto Ozeki , Haruo Yao , Tsutomu Okubo , Lekh Raj Juneja
发明人: Makoto Ozeki , Haruo Yao , Tsutomu Okubo , Lekh Raj Juneja
CPC分类号: A23G1/30 , A23G1/48 , A23G3/36 , A23G3/48 , A23G4/06 , A23G4/068 , A23L33/105 , A23L33/17 , A61K31/198
摘要: An object of the present invention is to provide a composition for promoting sleep, which any one can safely take on a daily basis without any risks of adverse action. In addition, an object of the present invention is to provide food and a medicament, comprising the above-mentioned composition, having an effect for promoting sleep for an individual having sleep disorders. Further, an object of the present invention is to provide a method for promoting sleep comprising administering theanine to an individual having sleep disorders, and use of theanine for preparation of the food or medicament for an individual having sleep disorders.
摘要翻译: 本发明的目的是提供一种用于促进睡眠的组合物,任何人可以每天安全地服用,而没有不利的作用的风险。 此外,本发明的目的是提供包含上述组合物的食物和药物,其具有促进具有睡眠障碍的个体的睡眠的效果。 此外,本发明的目的是提供一种促进睡眠的方法,其包括向具有睡眠障碍的个体施用茶氨酸,以及使用茶氨酸来制备具有睡眠障碍的个体的食物或药物。
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公开(公告)号:US11446319B2
公开(公告)日:2022-09-20
申请号:US17056552
申请日:2018-10-03
申请人: Masamitsu Moriwaki , Kentaro Kumoi , Ryo Nakagawa , Miki Sagisaka , Makoto Ozeki
发明人: Masamitsu Moriwaki , Kentaro Kumoi , Ryo Nakagawa , Miki Sagisaka , Makoto Ozeki
IPC分类号: A61K31/7048 , A61K47/69 , A61K8/60 , A61K8/73 , A23L29/30 , A23L33/105 , A23L27/00 , A23L5/41 , A23L2/60
摘要: A composition containing one or more materials selected from the group consisting of fatty acids, proteins, peptides, amino acids, vitamins, minerals, alcohols, sweeteners, acidulants, antioxidants, thickening stabilizer, and surfactants, and a flavonoid-cyclodextrin inclusion compound, wherein the inclusion compound contains an inclusion compound obtained by treating a flavonoid having a rhamnoside structure with an enzyme having rhamnosidase activity in the presence of a cyclodextrin. According to the present invention, the bitterness and the changes in color tones originated from flavonoids can be inhibited, and foodstuff or the like having an unpleasant taste can be improved, so that the present invention can be suitably utilized in fields such as medicaments, foodstuff, health foods, foods for specified health use, and cosmetics.
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公开(公告)号:US20190248825A1
公开(公告)日:2019-08-15
申请号:US16097120
申请日:2018-01-31
申请人: Masamitsu Moriwaki , Kentaro Kumoi , Makoto Ozeki
发明人: Masamitsu Moriwaki , Kentaro Kumoi , Makoto Ozeki
IPC分类号: C07H17/07 , A23L3/3499 , A61K47/40 , A61K8/60 , A61K8/73 , A61K31/7048
摘要: A method for producing a flavonoid inclusion compound, including a cleaving step including treating a sparingly soluble flavonoid having a rhamnoside structure with an enzyme having a rhamnosidase activity in the presence of a cyclodextrin to cleave a rhamnose. According to the production method of the present invention, a flavonoid inclusion compound and a composition of flavonoid glycosides having excellent solubility in water can be efficiently produced, so that the compound and composition can be suitably utilized in the fields of medicaments, foodstuff, health foods, foods for specified health use, cosmetics, and the like.
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公开(公告)号:US09180835B2
公开(公告)日:2015-11-10
申请号:US14350662
申请日:2011-10-11
申请人: Osamu Fukawatase , Makoto Ozeki
发明人: Osamu Fukawatase , Makoto Ozeki
IPC分类号: B60R21/231 , B60R21/206 , B60R21/2338 , B60R21/00
CPC分类号: B60R21/231 , B60R21/206 , B60R21/2338 , B60R2021/0004 , B60R2021/0051 , B60R2021/23169
摘要: Axial forces on the shins of small-bodied occupants and medium-bodied occupants may be suppressed or prevented, and protective performance of the knee areas of large-bodied occupants is assured. A vehicle knee airbag device is equipped with a knee airbag main body portion that is formed in a thin bag shape and that inflates and expands from below to above along a design surface of an instrument panel floor when gas is supplied thereto. A protection portion of the knee airbag main body portion has a size capable of covering both knees of an occupant, from small-bodied occupants to large-bodied occupants. A U-shaped lower tether is disposed in an upper portion of the interior of the protection portion; vertical direction dividing portions of the lower tether extend to the upward side from portions that correspond with both knees of medium-bodied occupants.
摘要翻译: 可以抑制或阻止对身体不便的乘客和中等体重的乘客的轴力作用,保证大身体的膝盖区域的保护性能。 车辆膝部安全气囊装置配备有膝盖安全气囊主体部,该气囊主体部形成为薄袋形状,并且当向其提供气体时沿着仪表板底板的设计表面从下方向下膨胀和膨胀。 膝部安全气囊本体部的保护部具有能够覆盖乘客的两膝盖的尺寸,从小身体到大身体。 U形下部系绳设置在保护部分内部的上部; 下部系绳的垂直方向分割部分从与中等体积的乘客的两膝相对应的部分向上延伸。
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