利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

14 条记录 (耗时 0.017 秒)

    Unsaturated fatty hydroxy acid derivatives and the dermocosmetologic use thereof
    1.
    发明授权
    Unsaturated fatty hydroxy acid derivatives and the dermocosmetologic use thereof 有权
    不饱和脂肪酸羟基酸衍生物及其皮肤用途

    公开(公告)号：US08158811B2

    公开(公告)日：2012-04-17

    申请号：US12083688

    申请日：2006-10-20

    申请人： Marie Charveron ,  Roger Tarroux ,  Pascal Bordat

    发明人： Marie Charveron ,  Roger Tarroux ,  Pascal Bordat

    IPC分类号： C07C59/00

    CPC分类号： C07C59/56 ,  C07C59/42

    摘要： The invention relates to unsaturated fatty hydroxy acid derivatives of formula (I), wherein Rn is independent from each other H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, in particular a fluorine atom, RI is H, F, Cl, Br or CF3, R is H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, in particular a fluorine atom and 3=n=14. Said derivatives is suitable for producing an anti-radical, anti-inflammatory and antipruritic dermocosmetologic composition and/or for treating keratinisation and pigmentation troubles and/or for improving healing.

    摘要翻译： 本发明涉及式（I）的不饱和脂肪酸羟基酸衍生物，其中R n彼此独立地为H或含有1至6个碳原子且可被卤素原子取代的直链或支链烷基，特别是 氟原子，R 1为H，F，Cl，Br或CF 3，R为H或含有1至6个碳原子并且可被卤素原子特别是氟原子取代的直链或支链烷基，且3 = n = 14。 所述衍生物适于产生抗自由基，抗炎和止痒皮肤组织学组合物和/或用于治疗角质化和色素沉着问题和/或改善愈合。

    Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof
    2.
    发明申请
    Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof 有权
    新型不饱和脂肪酸羟基衍生物及其皮肤用途

    公开(公告)号：US20090238784A1

    公开(公告)日：2009-09-24

    申请号：US12083688

    申请日：2006-10-20

    申请人： Marie Charveron ,  Roger Tarroux ,  Pascal Bordat

    发明人： Marie Charveron ,  Roger Tarroux ,  Pascal Bordat

    IPC分类号： A61K8/365 ,  C07C59/115 ,  A61Q19/02

    CPC分类号： C07C59/56 ,  C07C59/42

    摘要： The invention relates to unsaturated fatty hydroxy acid derivatives of formula (I), wherein Rn is independent from each other H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, in particular a fluorine atom, R1 is H, F, Cl, Br or CF3, R is H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, in particular a fluorine atom and 3=n=14. Said derivatives is suitable for producing an anti-radical, anti-inflammatory and antipruritic dermocosmetologic composition and/or for treating keratinisation and pigmentation troubles and/or for improving healing.

    摘要翻译： 本发明涉及式（I）的不饱和脂肪酸羟基酸衍生物，其中R n彼此独立地为H或含有1至6个碳原子且可被卤素原子取代的直链或支链烷基，特别是 氟原子，R 1是H，F，Cl，Br或CF 3，R是H或含有1至6个碳原子并且可以被卤素原子特别是氟原子取代的直链或支链烷基，3 = n = 14。 所述衍生物适于产生抗自由基，抗炎和止痒皮肤组织学组合物和/或用于治疗角质化和色素沉着问题和/或改善愈合。

    Polyunsaturated compounds, method for preparing same and compositions containing the same
    4.
    发明授权
    Polyunsaturated compounds, method for preparing same and compositions containing the same 失效
    多不饱和化合物，其制备方法和含有它们的组合物

    公开(公告)号：US08420610B2

    公开(公告)日：2013-04-16

    申请号：US12086625

    申请日：2006-12-14

    申请人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    发明人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    IPC分类号： A01N43/04 ,  A01N37/00 ,  A61K31/70 ,  A61K31/19 ,  C07H15/00 ,  C07C59/00

    CPC分类号： C07D339/04 ,  A61K8/33 ,  A61K8/37 ,  A61K8/4986 ,  A61K8/585 ,  A61K8/602 ,  A61Q19/02 ,  C07B2200/09 ,  C07C403/08 ,  C07C403/10 ,  C07C403/14 ,  C07C403/20 ,  C07C2601/16 ,  C07F7/081 ,  C07F7/0812 ,  C07H15/203

    摘要： The invention concerns novel polyunsaturated compounds of formula (I) wherein: R1 represents a R′1, -A-R′1 group, R′1 being selected from —COOH, —COOR3, —CONH2, —CONHR3, —CONR3 R4, —CHO, —CH2OH, —CH2OR5, and A represents a C2-C16 alkylene, alkenylene or alkynylene; R2 represents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a —OC —(CH2)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a —R′2—O—R6 group, wherein R′2 is an optionally substituted arylene group or an optionally substituted heteroarylene group, and R6 represents a hydrogen atom, a straight or branched optionally substituted C 1-C 16 alkyl, a straight or branched optionally substituted C2-C16 alkenyl, or a straight or branched C2-C16 alkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.

    摘要翻译： 本发明涉及式（I）的新型多不饱和化合物，其中：R1表示R'1，-AR'1基团，R'1选自-COOH，-COOR3，-CONH2，-CONHR3，-CONR3R4，-CHO ，-CH 2 OH，-CH 2 OR 5，A表示C 2 -C 16亚烷基，亚烯基或亚炔基; R2表示：任选取代的芳基或任选取代的杂芳基; 糖残基或脂肪酸残基，优选在链末端，特别是通过羟基，乙酰氧基或任选被保护的氨基部分支化和/或取代; a -OC-（CH 2）n CO-生育酚（α，β或γ或δ）组，其中2 $ m（F）n $ m（F）10; -R'2-O-R6基团，其中R'2是任选取代的亚芳基或任选取代的亚杂芳基，R 6表示氢原子，直链或支链任选取代的C 1 -C 16烷基，直链 或支链任选取代的C 2 -C 16烯基，或直链或支链C 2 -C 16炔基，任选取代的生育酚基等，氨基酸残基或糖残基。 本发明还涉及组合物，特别是包含至少一种式（I）化合物的化妆品和/或皮肤病学组合物，以及它们作为增白剂和/或脱色素剂的用途，以及使用所述组合物的美容方法。

    Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof
    5.
    发明授权
    Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof 有权
    单体5,6,6-二苯基-1.2.4-衍生物及其用途

    公开(公告)号：US08053573B2

    公开(公告)日：2011-11-08

    申请号：US11579341

    申请日：2005-05-04

    申请人： Jérôme Rey ,  Pascal Bordat ,  Roger Tarroux

    发明人： Jérôme Rey ,  Pascal Bordat ,  Roger Tarroux

    IPC分类号： C07D253/065 ,  C07D253/07 ,  A61K31/53 ,  A61K8/49 ,  A61Q5/12 ,  A61Q17/04

    CPC分类号： C07D253/065 ,  A61K8/4966 ,  A61Q17/04 ,  C07D253/07

    摘要： The invention relates to the use of 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein cycle penetrating bonds display an ortho, meta or para indifferent substitution position, identical or different R1 and R2 represent a hydrogen, fluoride, chloride or bromine atom, C1 to C12 linear or branched alkyl, C1 A C18 linear or branched hydroxy, alkoxy poly(ethoxy)-alkoxy with a C1 to C4 alkyl fragment and an ethoxy number ranging from 1 to 4, amino or mono or di-alkylamino with a C1 to C4 alkyl fragment group, R3 represents a chlorine atom, a hydroxy, amino, a phenyl possibly 1 to 3 times substituted by a hydroxy radical situated at least in a para or phenyl position possibly 1 to 3 times substituted in an ortho, meta or para position by a C1 to C12 alkoxy or cyano or alkymino group with a C1 to C7 alkyl fragment in the form of active sun filters or light-protective agents and to cosmetic composition containing said compounds.

    摘要翻译： 本发明涉及通式（I）的5,6-二苯基-1,2,4-三嗪化合物的用途，其中循环穿透键显示相邻或不同的取代位置，相同或不同的R 1和R 2表示 C 1 -C 12直链或支链烷基，C 1 -C 18直链或支链羟基，具有C1至C4烷基片段的烷氧基聚（乙氧基） - 烷氧基和1至4的乙氧基， 氨基或一或二烷基氨基与C 1至C 4烷基片基，R 3表示氯原子，羟基，氨基，可被1至3倍被至少位于对位或苯基位置的羟基取代的苯基，可能为1 以C1-C12烷氧基或氰基或烷基氨基取代邻位，间位或对位至活性阳离子或光保护剂形式的C 1至C 7烷基片段，并含有所述化合物的化妆品组合物。

    5,6-Diphenyl-1,2,4-Triazinic Dimeric Derivatives and the Use Thereof in the Form of Sun-Protective Agents
    6.
    发明申请
    5,6-Diphenyl-1,2,4-Triazinic Dimeric Derivatives and the Use Thereof in the Form of Sun-Protective Agents 有权
    5,6-二苯基-1,2,4-三嗪二聚衍生物及其用途以防晒剂的形式

    公开(公告)号：US20080267892A1

    公开(公告)日：2008-10-30

    申请号：US11579538

    申请日：2005-05-04

    申请人： Willy Picoul ,  Marco Ciufolini ,  Pascal Bordat ,  Roger Tarroux

    发明人： Willy Picoul ,  Marco Ciufolini ,  Pascal Bordat ,  Roger Tarroux

    IPC分类号： A61K8/49 ,  C07D403/10 ,  A61Q17/04

    CPC分类号： C07D253/065 ,  A61K8/4966 ,  A61Q17/04

    摘要： The invention relates to 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein identical or different R1, R2, R3 and R4 represent a hydrogen, fluoride, chloride or bromine atom, C1 to C12 linear or branched alkyl, C1 A C18 linear or branched hydroxy, alkoxy poly(ethoxy)-alkoxy with a C1 to C4 alkyl fragment and an ethoxy number ranging from 1 to 4, amino or mono or di-alkylamino with a C1 to C4 alkyl fragment group, X is ortho-, meta- or paraphenylene, 4,4′-biphenylene, 2,4- or 2,6- or 3,4- or 3,5-pyridinylene, 2,2′-bipyridinylene, meta- or paraphenylenediamino, ethylenediamine, 2,2′-piperazinylene, diacyl of formula -(R4CO)2-, wherein r represents a phenyl radical, a 3 to 10 carbon, phenanthrene or anthracene atoms alkyl chain except 1,4-bis(5,6-diphenyl-1,2,4-triazin-3-yl)benzene of 2,4-bis(5,6-diphenyl-1,2,4-triazin-3-yl)pyridine and of 2,6-bis(5,6-diphenyl-1,2,4-triazin-3-yl)pyridine, to cosmetic compositions containing said compounds and to the use thereof in the form of sun filters or light-protective agents.

    摘要翻译： 本发明涉及通式（I）的5,6-二苯基-1,2,4-三嗪化合物，其中相同或不同的R 1，R 2，R 3和R 4表示氢，氟，氯或溴原子，C 1至C 12 直链或支链烷基，C1-C18直链或支链羟基，具有C1至C4烷基片段的烷氧基聚（乙氧基） - 烷氧基和1至4个乙氧基，氨基或具有C1至C4烷基的单烷基或二烷基氨基 片段基团，X是邻 - ，间 - 或对 - 亚苯基，4,4'-亚联苯基，2,4-或2,6-或3,4-或3,5-亚吡啶基，2,2'-联吡啶亚基， 或对亚苯基二氨基，乙二胺，2,2'-哌嗪基，式 - （R 4 CO）2 - 的二酰基，其中r表示苯基，除了1,4-双（5， （5,6-二苯基-1,2,4-三嗪-3-基）吡啶和2,6-双（5,6-二苯基-1,2,4-三嗪-3-基） （5,6-二苯基-1,2,4-三嗪-3-基）吡啶，含有所述化合物的化妆品组合物及其用途 形式的太阳过滤器或防晒剂。

    UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY
    8.
    发明申请
    UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY 审中-公开
    不饱和脂肪氨基酸衍生物及其在真菌学中的应用

    公开(公告)号：US20100240754A1

    公开(公告)日：2010-09-23

    申请号：US12523231

    申请日：2008-01-16

    申请人： Roger Tarroux ,  Marie Charveron ,  Sylvie Daunes-Marion ,  Natacha Frison ,  Benôit Folleas ,  Jean-Louis Brayer

    发明人： Roger Tarroux ,  Marie Charveron ,  Sylvie Daunes-Marion ,  Natacha Frison ,  Benôit Folleas ,  Jean-Louis Brayer

    IPC分类号： C07C229/30 ,  C07C227/00 ,  A61K31/197 ,  A61K8/44 ,  A61Q19/08 ,  A61P17/00

    CPC分类号： C07C229/30 ,  C07C227/00 ,  C07C237/16

    摘要： The present invention relates to drugs consisting of unsaturated fatty amino-acid derivatives of the general formula (I), and to their pharmaceutically acceptable acid addition salts, in which: X is oxygen or NH, Rn are independently hydrogen or a (C1-C6)alkyl optionally substituted by halogen; R1 is hydrogen, fluorine, chlorine or bromine, or a CF3 or CHF2 or a (C1-C6)alkyl, (C1-C6)alkenyl or (C1-C6)alkynyl, optionally substituted by one or more halogen atoms; R is hydrogen or a (C1-C6)alkyl or (C3-C6)cycloalkyl optionally substituted by one or more halogen atoms; Ra and Rb are independently hydrogen (C1-C6)alkyl or (C1-C6)acyl, and Ra and Rb a hydrocarbonated cycle containing 4 to 6 carbon atoms; and n is an integer between 2 and 14.

    摘要翻译： 本发明涉及由通式（I）的不饱和脂肪氨基酸衍生物及其药学上可接受的酸加成盐组成的药物，其中：X为氧或NH，R n独立地为氢或（C 1 -C 6 ）烷基任选被卤素取代; R 1是任选被一个或多个卤素原子取代的氢，氟，氯或溴，或CF 3或CHF 2或（C 1 -C 6）烷基，（C 1 -C 6）烯基或（C 1 -C 6） R是氢或任选被一个或多个卤素原子取代的（C 1 -C 6）烷基或（C 3 -C 6）环烷基; Ra和Rb独立地是氢（C1-C6）烷基或（C1-C6）酰基，Ra和Rb是含有4-6个碳原子的烃基; n为2〜14的整数。

    5,6-diphenyl-1,2,4-triazinic dimeric derivatives and the use thereof in the form of sun-protective agents
    9.
    发明授权
    5,6-diphenyl-1,2,4-triazinic dimeric derivatives and the use thereof in the form of sun-protective agents 有权
    5,6-二苯基-1,2,4-三嗪二聚体衍生物及其以防晒剂形式的用途

    公开(公告)号：US07816520B2

    公开(公告)日：2010-10-19

    申请号：US11579538

    申请日：2005-05-04

    申请人： Willy Picoul ,  Marco Ciufolini ,  Pascal Bordat ,  Roger Tarroux

    发明人： Willy Picoul ,  Marco Ciufolini ,  Pascal Bordat ,  Roger Tarroux

    IPC分类号： C07D403/10 ,  C07D403/12 ,  C07D403/14 ,  A61K8/49 ,  A61Q17/04

    CPC分类号： C07D253/065 ,  A61K8/4966 ,  A61Q17/04

    摘要： The invention relates to 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein identical or different R1, R2, R3 and R4 represent a hydrogen, fluoride, chloride or bromine atom, C1 to C12 linear or branched alkyl, C1 A C18 linear or branched hydroxy, alkoxy poly(ethoxy)-alkoxy with a C1 to C4 alkyl fragment and an ethoxy number ranging from 1 to 4, amino or mono or di-alkylamino with a C1 to C4 alkyl fragment group, X is ortho-, meta- or paraphenylene, 4,4′-biphenylene, 2,4- or 2,6- or 3,4- or 3,5-pyridinylene, 2,2′-bipyridinylene, meta- or paraphenylenediamino, ethylenediamine, 2,2′-piperazinylene, diacyl of formula -(R4CO)2-, wherein r represents a phenyl radical, a 3 to 10 carbon, phenanthrene or anthracene atoms alkyl chain except 1,4-bis(5,6-diphenyl-1,2,4-triazin-3-yl)benzene of 2,4-bis(5,6-diphenyl-1,2,4-triazin-3-yl)pyridine and of 2,6-bis(5,6-diphenyl-1,2,4-triazin-3-yl)pyridine, to cosmetic compositions containing said compounds and to the use thereof in the form of sun filters or light-protective agents.

    摘要翻译： 本发明涉及通式（I）的5,6-二苯基-1,2,4-三嗪化合物，其中相同或不同的R 1，R 2，R 3和R 4表示氢，氟，氯或溴原子，C 1至C 12 直链或支链烷基，C1-C18直链或支链羟基，具有C1至C4烷基片段的烷氧基聚（乙氧基） - 烷氧基和1至4个乙氧基，氨基或具有C1至C4烷基的单烷基或二烷基氨基 片段基团，X是邻 - ，间 - 或对 - 亚苯基，4,4'-亚联苯基，2,4-或2,6-或3,4-或3,5-亚吡啶基，2,2'-联吡啶亚基， 或对亚苯基二氨基，乙二胺，2,2'-哌嗪基，式 - （R 4 CO）2 - 的二酰基，其中r表示苯基，除了1,4-双（5， （5,6-二苯基-1,2,4-三嗪-3-基）吡啶和2,6-双（5,6-二苯基-1,2,4-三嗪-3-基） （5,6-二苯基-1,2,4-三嗪-3-基）吡啶，含有所述化合物的化妆品组合物及其用途i n是太阳过滤器或防晒剂的形式。

    Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same
    10.
    发明申请
    Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same 失效
    新型多不饱和化合物，其制备方法及其组合物

    公开(公告)号：US20100168045A1

    公开(公告)日：2010-07-01

    申请号：US12086625

    申请日：2006-12-14

    申请人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    发明人： Pascal Bordat ,  Roger Tarroux ,  Jean-Hilaire Saurat ,  Olivier Sorg ,  Jean-Louis Brayer ,  Natacha Frison

    IPC分类号： A61K8/37 ,  C07H15/207 ,  A61K8/60 ,  C07C69/736 ,  C07C47/277 ,  C07C69/587 ,  C07D339/04 ,  A61K8/49 ,  C07D311/72 ,  A61K8/67 ,  C07C69/738 ,  A61K8/34 ,  A61K8/33 ,  A61Q5/00 ,  A61Q19/02

    CPC分类号： C07D339/04 ,  A61K8/33 ,  A61K8/37 ,  A61K8/4986 ,  A61K8/585 ,  A61K8/602 ,  A61Q19/02 ,  C07B2200/09 ,  C07C403/08 ,  C07C403/10 ,  C07C403/14 ,  C07C403/20 ,  C07C2601/16 ,  C07F7/081 ,  C07F7/0812 ,  C07H15/203

    摘要： The invention concerns novel polyunsaturated compounds of formula (I) wherein: R1 represents a R′1, -A-R′1 group, R′1 being selected from —COOH, —COOR3, —CONH2, —CONHR3, —CONR3, R4, —CHO, —CH2OH, —CH2OR5, and A represents a C2-C16 alkylene, alkenylene or alkynylene; R2 represents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a —OC—(CH2)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a —R′2—O—R6 group, wherein R′2 is an optionally substituted arylene group or an optionally substituted heteroarylene group, and R6 represents a hydrogen atom, a straight or branched optionally substituted C1-C16 alkyl, a straight or branched optionally substituted C2-C16 alkenyl, or a straight or branched C2-C16 alkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.

    摘要翻译： 本发明涉及式（I）的新型多不饱和化合物，其中：R1表示R'1，-AR'1基团，R'1选自-COOH，-COOR3，-CONH2，-CONHR3，-CONR3，R4， - CHO，-CH2OH，-CH2OR5和A表示C2-C16亚烷基，亚烯基或亚炔基; R2表示：任选取代的芳基或任选取代的杂芳基; 糖残基或脂肪酸残基，优选在链末端，特别是羟基，乙酰氧基或任选被保护的氨基上任选地支链和/或取代; a -OC-（CH 2）n CO-生育酚（α，β或γ或δ）组，其中2 $ m（F）n $ m（F）10; -R'2-O-R6基团，其中R'2是任选取代的亚芳基或任选取代的亚杂芳基，R 6表示氢原子，直链或支链任选取代的C 1 -C 16烷基，直链或支链 任选取代的C 2 -C 16烯基，或直链或支链C 2 -C 16炔基，任选取代的生育酚基等，氨基酸残基或糖残基。 本发明还涉及组合物，特别是包含至少一种式（I）化合物的化妆品和/或皮肤病学组合物，以及它们作为增白剂和/或脱色素剂的用途，以及使用所述组合物的美容方法。