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    UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY
    1.
    发明申请
    UNSATURATED FATTY AMINO ACID DERIVATIVES AND USE THEREOF IN DERMAL COSMETOLOGY 审中-公开
    不饱和脂肪氨基酸衍生物及其在真菌学中的应用

    公开(公告)号：US20100240754A1

    公开(公告)日：2010-09-23

    申请号：US12523231

    申请日：2008-01-16

    申请人： Roger Tarroux ,  Marie Charveron ,  Sylvie Daunes-Marion ,  Natacha Frison ,  Benôit Folleas ,  Jean-Louis Brayer

    发明人： Roger Tarroux ,  Marie Charveron ,  Sylvie Daunes-Marion ,  Natacha Frison ,  Benôit Folleas ,  Jean-Louis Brayer

    IPC分类号： C07C229/30 ,  C07C227/00 ,  A61K31/197 ,  A61K8/44 ,  A61Q19/08 ,  A61P17/00

    CPC分类号： C07C229/30 ,  C07C227/00 ,  C07C237/16

    摘要： The present invention relates to drugs consisting of unsaturated fatty amino-acid derivatives of the general formula (I), and to their pharmaceutically acceptable acid addition salts, in which: X is oxygen or NH, Rn are independently hydrogen or a (C1-C6)alkyl optionally substituted by halogen; R1 is hydrogen, fluorine, chlorine or bromine, or a CF3 or CHF2 or a (C1-C6)alkyl, (C1-C6)alkenyl or (C1-C6)alkynyl, optionally substituted by one or more halogen atoms; R is hydrogen or a (C1-C6)alkyl or (C3-C6)cycloalkyl optionally substituted by one or more halogen atoms; Ra and Rb are independently hydrogen (C1-C6)alkyl or (C1-C6)acyl, and Ra and Rb a hydrocarbonated cycle containing 4 to 6 carbon atoms; and n is an integer between 2 and 14.

    摘要翻译： 本发明涉及由通式（I）的不饱和脂肪氨基酸衍生物及其药学上可接受的酸加成盐组成的药物，其中：X为氧或NH，R n独立地为氢或（C 1 -C 6 ）烷基任选被卤素取代; R 1是任选被一个或多个卤素原子取代的氢，氟，氯或溴，或CF 3或CHF 2或（C 1 -C 6）烷基，（C 1 -C 6）烯基或（C 1 -C 6） R是氢或任选被一个或多个卤素原子取代的（C 1 -C 6）烷基或（C 3 -C 6）环烷基; Ra和Rb独立地是氢（C1-C6）烷基或（C1-C6）酰基，Ra和Rb是含有4-6个碳原子的烃基; n为2〜14的整数。

    Unsaturated fatty acid monoesters and diesters on ascorbic acid and cosmetic uses thereof
    5.
    发明授权
    Unsaturated fatty acid monoesters and diesters on ascorbic acid and cosmetic uses thereof 失效
    抗坏血酸的不饱和脂肪酸单酯和二酯及其化妆品用途

    公开(公告)号：US08722729B2

    公开(公告)日：2014-05-13

    申请号：US13376752

    申请日：2010-06-08

    申请人： Stéphane Poigny ,  Sylvie Daunes-Marion ,  Nathalie Castex Rizzi ,  Patrick Bogdanowicz

    发明人： Stéphane Poigny ,  Sylvie Daunes-Marion ,  Nathalie Castex Rizzi ,  Patrick Bogdanowicz

    IPC分类号： A01N43/26 ,  C07D307/62

    CPC分类号： C07D407/04

    摘要： The present invention relates to a compound with the following general formula (I): in which: R1 is a hydrocarbon chain of an unsaturated fatty acid from C12 to C24 including at least one unsaturation; and R2 and R3 are, independently or simultaneously: a hydrogen or a C1-C3 alkyl or a phenyl; and R4: a hydrogen atom or COR1′, where R1′ is a hydrocarbon chain of an unsaturated fatty acid from C12 to C24 including at least one unsaturation, advantageously 1 to 6 and preferably 1 to 4.

    摘要翻译： 本发明涉及具有以下通式（I）的化合物：其中：R1是包含至少一个不饱和键的C12-C24不饱和脂肪酸的烃链; 和R 2和R 3独立地或同时地是氢或C 1 -C 3烷基或苯基; 和R 4：氢原子或COR 1'，其中R 1'是C 12至C 24不饱和脂肪酸的烃链，其包含至少一个不饱和键，有利地为1至6个，优选1至4个。

    Polyunsaturated fatty acid and diol ester as an anti-acne agent
    7.
    发明授权
    Polyunsaturated fatty acid and diol ester as an anti-acne agent 有权
    多不饱和脂肪酸和二醇酯作为抗痤疮剂

    公开(公告)号：US08623916B2

    公开(公告)日：2014-01-07

    申请号：US13130900

    申请日：2009-12-21

    申请人： Daniel Redoules ,  Sylvie Daunes-Marion ,  Marie-Françoise Aries

    发明人： Daniel Redoules ,  Sylvie Daunes-Marion ,  Marie-Françoise Aries

    IPC分类号： A61K31/22 ,  A23D9/00 ,  C11C3/00

    CPC分类号： C07C69/587

    摘要： The present invention relates to compounds of the following formula (I): where n is an integer between 1 and 15, m is 0, 1, 2 or 3, and R is the hydrocarbon chain of a polyunsaturated fatty acid selected from among omega 3 and omega 6, as well as to pharmaceutical or cosmetic compositions containing same, to a method for preparing and using same, in particular for treating acne and seborrhoeic dermatitis.

    摘要翻译： 本发明涉及下式（I）的化合物：其中n为1至15之间的整数，m为0,1,2或3，R为选自ω3中的多不饱和脂肪酸的烃链 和ω6，以及含有其的药物或化妆品组合物，其制备和使用方法，特别是用于治疗痤疮和脂溢性皮炎。