摘要:
Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, p, R1, R2, R3a, R4, and R5 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, cancer, and other disorders, diseases, and conditions for which inhibition of SYK is indicated.
摘要:
The present invention provides compounds of formula I: which are useful as modulators of GPR6, pharmaceutical compositions thereof, methods for treatment of conditions associated with GPR6, processes for making the compounds and intermediates thereof.
摘要:
A continuity bridge in a broadband signal tap for providing a make-before-break connection of an input terminal to an output terminal of the tap. The broadband signal tap comprises a housing and a cover that is removably connected to the housing. The interior of the housing has an input terminal for receiving a signal from the feeder cable and an output terminal for returning the signal to the feeder cable. The cover includes circuitry for splitting the signal and delivering a portion thereof to at least one subscriber port on the cover. The cover has an input socket and an output socket, each being removably engaged with and electrically connected to the input and output terminals, respectively, of the housing. The continuity bridge in the housing connects the input terminal to the output terminal upon the removal of the cover from the housing prior to the disengagement of the sockets from the terminals. The continuity bridge thus provides a make-before-break connection of the input terminal to the output terminal, thereby ensuring that there is no discontinuity of signal flow through the tap upon the removal of the cover from the housing.
摘要:
A system and method for monitoring performance of a wireless network are disclosed. According to one described example, at least one probe is generated. In the example, the probe determines the portion of a wireless network to monitor, the type of the probe, and the number and frequency of the probe or probes to target a specific carrier, a specific system, or a specific geographical area. A probe server generates the probe based on a parameter specified by the user and transmits the probe to a plurality of posts or to the wireless network. In the example, the probe server controls the posts to send and receive probes to the wireless network. In response to the received probes, the wireless network responds by sending feedback information, which can be used to indicate how the wireless network is performing.
摘要:
A system and method are disclosed for monitoring performance of a wireless network. A probe server controls posts to send and receive probes of the wireless network. Wireless devices at the posts send the probes to the wireless network and receive probes from the wireless network. These probes provide feedback information, which indicates how the wireless network is performing.
摘要:
A system and method for monitoring performance of a wireless network. A probe server controls posts to send and receive probes of the wireless network. These probes provide feedback information, which indicates how the wireless network is performing.
摘要:
A system and method for monitoring performance of a wireless network are disclosed. According to one described example, at least one probe is generated. In the example, the probe determines the portion of a wireless network to monitor, the type of the probe, and the number and frequency of the probe or probes to target a specific carrier, a specific system, or a specific geographical area. A probe server generates the probe based on a parameter specified by the user and transmits the probe to a plurality of posts or to the wireless network. In the example, the probe server controls the posts to send and receive probes to the wireless network. In response to the received probes, the wireless network responds by sending feedback information, which can be used to indicate how the wireless network is performing.
摘要:
Novel non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described.
摘要:
Compounds, pharmaceutical compositions, kits and methods are provided for use with MEK that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.
摘要:
Compounds, pharmaceutical compositions, kits and methods are provided for use with MEK that comprise a compound selected from the group consisting of: wherein the variables are as defined herein.