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公开(公告)号:US07790421B2
公开(公告)日:2010-09-07
申请号:US11483495
申请日:2006-07-10
申请人: Markus Kurz , Peter Lohse , Richard W. Wagner
发明人: Markus Kurz , Peter Lohse , Richard W. Wagner
IPC分类号: C12P19/34
CPC分类号: C12P19/34 , C07K1/1077 , C07K17/02 , C12N15/1006 , C12N15/1062 , C12N15/1075 , C12N15/11
摘要: Described herein are methods and reagents for the ligation of a peptide acceptor to an RNA, as well as the RNA-peptide acceptor products.
摘要翻译: 本文描述了用于将肽受体与RNA连接的方法和试剂,以及RNA-肽受体产物。
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公开(公告)号:US06416950B1
公开(公告)日:2002-07-09
申请号:US09453190
申请日:1999-12-02
申请人: Peter Lohse , Markus Kurz
发明人: Peter Lohse , Markus Kurz
IPC分类号: C12Q168
CPC分类号: C12N15/1096 , C07B2200/11 , C07H19/20 , C07H21/00 , C07K14/00 , C12N15/1062 , C12N15/1075 , C40B30/04 , C40B40/00 , C40B40/08 , C40B40/10 , C40B50/14
摘要: Disclosed herein are molecules that include a deoxyribonucleic acid (DNA) covalently bonded to a protein and uses thereof.
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公开(公告)号:US20060246549A1
公开(公告)日:2006-11-02
申请号:US11483495
申请日:2006-07-10
申请人: Markus Kurz , Peter Lohse , Richard Wagner
发明人: Markus Kurz , Peter Lohse , Richard Wagner
CPC分类号: C12P19/34 , C07K1/1077 , C07K17/02 , C12N15/1006 , C12N15/1062 , C12N15/1075 , C12N15/11
摘要: Described herein are methods and reagents for the ligation of a peptide acceptor to an RNA, as well as the RNA-peptide acceptor products.
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公开(公告)号:US06951725B2
公开(公告)日:2005-10-04
申请号:US10176826
申请日:2002-06-20
申请人: Markus Kurz , Peter Lohse
发明人: Markus Kurz , Peter Lohse
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6897 , C12N15/1055 , C12N15/1062 , C12N15/1075 , C12Q2565/201 , C12Q2525/203
摘要: Disclosed herein are in vitro assays for the identification of interactions between proteins or other molecules, the identification of transcriptional activator proteins, and the detection of compounds that inhibit protein/protein or protein/compound interactions. Also disclosed herein are in vitro assays for the selection of interacting proteins and transcriptional activator proteins out of libraries.
摘要翻译: 本文公开了用于鉴定蛋白质或其他分子之间的相互作用的体外测定,转录激活蛋白的鉴定以及抑制蛋白质/蛋白质或蛋白质/化合物相互作用的化合物的检测。 本文还公开了用于从文库中选择相互作用蛋白和转录激活蛋白的体外测定。
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公开(公告)号:US20080051299A1
公开(公告)日:2008-02-28
申请号:US11726717
申请日:2007-03-22
申请人: Peter Lohse , Markus Kurz
发明人: Peter Lohse , Markus Kurz
CPC分类号: C12N15/1096 , C07B2200/11 , C07H19/20 , C07H21/00 , C07K14/00 , C12N15/1062 , C12N15/1075 , C40B30/04 , C40B40/00 , C40B40/08 , C40B40/10 , C40B50/14
摘要: Disclosed herein are molecules that include a deoxyribonucleic acid (DNA) covalently bonded to a protein and uses thereof.
摘要翻译: 本文公开了包含共价键合到蛋白质上的脱氧核糖核酸(DNA)和其用途的分子。
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公开(公告)号:US07195880B2
公开(公告)日:2007-03-27
申请号:US10180819
申请日:2002-06-26
申请人: Peter Lohse , Markus Kurz
发明人: Peter Lohse , Markus Kurz
CPC分类号: C12N15/1096 , C07B2200/11 , C07H19/20 , C07H21/00 , C07K14/00 , C12N15/1062 , C12N15/1075 , C40B30/04 , C40B40/00 , C40B40/08 , C40B40/10 , C40B50/14
摘要: Disclosed herein are molecules that include a deoxyribonucleic acid (DNA) covalently bonded to a protein and uses thereof.
摘要翻译: 本文公开了包含共价键合到蛋白质上的脱氧核糖核酸(DNA)和其用途的分子。
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公开(公告)号:US07078197B2
公开(公告)日:2006-07-18
申请号:US10208357
申请日:2002-07-30
申请人: Markus Kurz , Peter Lohse , Richard Wagner
发明人: Markus Kurz , Peter Lohse , Richard Wagner
IPC分类号: C12P19/34
CPC分类号: C12P19/34 , C07K1/1077 , C07K17/02 , C12N15/1006 , C12N15/1062 , C12N15/1075 , C12N15/11
摘要: Described herein are methods and reagents for the ligation of a peptide acceptor to an RNA, as well as the RNA-peptide acceptor products.
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公开(公告)号:US06429300B1
公开(公告)日:2002-08-06
申请号:US09619103
申请日:2000-07-19
申请人: Markus Kurz , Peter Lohse , Richard Wagner
发明人: Markus Kurz , Peter Lohse , Richard Wagner
IPC分类号: C07H2102
CPC分类号: C12P19/34 , C07K1/1077 , C07K17/02 , C12N15/1006 , C12N15/1062 , C12N15/1075 , C12N15/11
摘要: Described herein are methods and reagents for the ligation of a peptide acceptor to an RNA, as well as the RNA-peptide acceptor products.
摘要翻译: 本文描述了用于将肽受体与RNA连接的方法和试剂,以及RNA-肽受体产物。
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公开(公告)号:US07902192B2
公开(公告)日:2011-03-08
申请号:US10556161
申请日:2004-05-14
申请人: Mark A. Ashwell , Syed Ali , Jifeng Liu , Yanbin Liu , Peter Lohse , Belew Mekonnen , Robert Selliah , Manish Tandon , Woj Wrona , Valery Antonenko
发明人: Mark A. Ashwell , Syed Ali , Jifeng Liu , Yanbin Liu , Peter Lohse , Belew Mekonnen , Robert Selliah , Manish Tandon , Woj Wrona , Valery Antonenko
IPC分类号: C07D498/04 , A61K31/41
CPC分类号: C07D513/04 , Y02P20/582
摘要: In general, the present invention relates to compounds capable of inhibiting p38, methods for inhibiting p38 in vivo or in vitro, and methods for treating conditions associated with p38 activity or cytokine activity.
摘要翻译: 通常,本发明涉及能够抑制p38的化合物,体内或体外抑制p38的方法,以及用于治疗与p38活性或细胞因子活性相关的病症的方法。
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公开(公告)号:US06660473B1
公开(公告)日:2003-12-09
申请号:US09614264
申请日:2000-07-12
IPC分类号: C12Q1688
CPC分类号: C07K1/1077 , C07K1/13 , G01N33/532 , Y10T436/143333
摘要: In general, the invention features proteins having covalently bonded C-terminal puromycin tags and methods for their production.
摘要翻译: 通常,本发明的特征在于具有共价键合的C-末端嘌呤霉素标签的蛋白质及其生产方法。
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