Method for producing a drug delivery system on the basis of polyelectrolyte complexes
    2.
    发明授权
    Method for producing a drug delivery system on the basis of polyelectrolyte complexes 有权
    基于聚电解质复合物制备药物递送系统的方法

    公开(公告)号:US09078805B2

    公开(公告)日:2015-07-14

    申请号:US13638413

    申请日:2011-03-30

    申请人: Martin Mueller

    发明人: Martin Mueller

    摘要: A method that relates to the fields of polymer chemistry, pharmacy and medicine and releases drugs as a component of implants into the environment of the implant. A method that, in a simple and easily reproducible manner, generates a drug delivery system, which releases drugs in a locally targeted and controllably delayed manner. Polyanions and polycations are mixed in a liquid in a non-stoichiometric ratio, relative to the charged monomer units, wherein drugs are added to the polyelectrolytes either before, during or after the mixing, or charge-carrying drugs and an oppositely charged polyelectrolyte are mixed, and after the mixing the polyelectrolyte complex produced is applied to the surface of a medical structure or material or is positioned on the surface directly at the location where the drug is to be released.

    摘要翻译: 涉及聚合物化学,药学和药物领域的方法,并将药物作为植入物植入物的组分的一部分释放出来。 一种以简单且容易重复的方式产生药物递送系统的方法,其以局部目标和可控地延迟的方式释放药物。 聚阴离子和聚阳离子相对于带电单体单元以非化学计量比混合在液体中,其中药物在混合之前,期间或之后或电荷携带药物和相反电荷的聚电解质混合时加入到聚电解质中 并且在混合之后,所制备的聚电解质复合物被施加到医疗结构或材料的表面,或者直接位于待释放药物的位置的表面上。

    View life cycle management
    3.
    发明授权
    View life cycle management 有权
    查看生命周期管理

    公开(公告)号:US08977608B2

    公开(公告)日:2015-03-10

    申请号:US12962586

    申请日:2010-12-07

    IPC分类号: G06F17/30 G06F7/00

    CPC分类号: G06F17/30383

    摘要: The subject matter disclosed herein provides, methods and apparatus, including computer program products for the management of a view of a data structure. In one aspect, there is provided a method that may include generating a view of a data structure. The data structure and the view may include a plurality of nodes and at least one association. This method may further include determining, at run time, whether the generated view is invalid based on an indicator. The indicator may represent whether a change has occurred to a system including the view. This method may further include deleting, at run time, the view based on the results of the determining. Related apparatus, systems, techniques and articles are also described.

    摘要翻译: 本文公开的主题提供了包括用于管理数据结构视图的计算机程序产品的方法和装置。 在一个方面,提供了可以包括生成数据结构的视图的方法。 数据结构和视图可以包括多个节点和至少一个关联。 该方法还可以包括在运行时确定基于指示符生成的视图是否无效。 指示符可以表示包括视图的系统是否发生了改变。 该方法还可以包括在运行时基于确定的结果删除视图。 还描述了相关设备,系统,技术和物品。

    VALVE FOR METERING A FLOWING MEDIUM
    4.
    发明申请
    VALVE FOR METERING A FLOWING MEDIUM 有权
    用于计量流动介质的阀

    公开(公告)号:US20150041565A1

    公开(公告)日:2015-02-12

    申请号:US14377483

    申请日:2013-01-25

    申请人: Martin Mueller

    发明人: Martin Mueller

    IPC分类号: F02M61/16 F02M63/00

    摘要: A valve for metering a flowing medium, particularly a fluid, which has a filter situated in the medium stream and has a filter ring that includes a plurality of filter pores and a support element supporting the filter ring on its outgoing flow side. The support element is developed as a radially elastic support ring having a plurality of through holes, which rests against the filter ring with radial prestressing.

    摘要翻译: 一种用于计量流动介质,特别是流体的阀,其具有位于介质流中的过滤器,并且具有包括多个过滤器孔的过滤环和在其流出侧支撑过滤环的支撑元件。 支撑元件被开发成具有多个通孔的径向弹性支撑环,该通孔以径向预应力靠在过滤环上。

    Arrangement for holding a substrate in a material deposition apparatus
    5.
    发明授权
    Arrangement for holding a substrate in a material deposition apparatus 有权
    用于将材料保持在材料沉积设备中的布置

    公开(公告)号:US08808402B2

    公开(公告)日:2014-08-19

    申请号:US13262776

    申请日:2010-03-29

    IPC分类号: H01L51/40

    CPC分类号: C23C14/042 C23C14/50

    摘要: An arrangement (1) for holding a substrate (10) in a material deposition apparatus, which substrate (10) has a deposition side (10a) upon which material (M) is to be deposited, and which arrangement (1) comprises: a shadow mask (20) comprising a number of deposition openings (Di); a support structure (30) comprising a number of surround openings (Si); and a support structure holding means (6) for holding the support mask (30) and/or a substrate holding means (5) for holding the substrate (10), such that the support structure (30) is on the same side as the deposition side (10a) of the substrate (10), and the shadow mask (20) is positioned between the substrate (10) and the support structure (30) such that at least one deposition opening (Di) of the shadow mask (10) lies within a corresponding surround opening (Si) of the support structure (30).

    摘要翻译: 一种用于将材料(10)保持在材料沉积装置中的装置(1),所述衬底(10)具有要沉积材料(M)的沉积侧(10a),并且所述装置(1)包括: 包括多个沉积开口(Di)的荫罩(20); 包括多个环绕开口(Si)的支撑结构(30); 以及用于保持支撑掩模(30)的支撑结构保持装置(6)和/或用于保持基板(10)的基板保持装置(5),使得支撑结构(30)位于与 所述基板(10)的沉积侧(10a)和所述荫罩(20)位于所述基板(10)和所述支撑结构(30)之间,使得所述荫罩(10)的至少一个沉积开口(Di) )位于支撑结构(30)的相应环绕开口(Si)内。

    DEVICE FOR INJECTING FUEL
    6.
    发明申请
    DEVICE FOR INJECTING FUEL 审中-公开
    注射燃料的装置

    公开(公告)号:US20130284828A1

    公开(公告)日:2013-10-31

    申请号:US13879247

    申请日:2011-09-21

    申请人: Martin Mueller

    发明人: Martin Mueller

    IPC分类号: F02M51/06

    摘要: A device for injecting fuel includes an outwardly opening valve needle, a piezo actuator connected to the valve needle, a valve body having a first through-opening, and a holding body connected to the valve body and having a second through-opening. The valve body has a valve seat and a first guide region for guiding the valve needle, the valve needle being disposed in the valve body and in the holding body, and the first through-opening is formed in the valve body without undercutting.

    摘要翻译: 用于喷射燃料的装置包括向外打开的阀针,连接到阀针的压电致动器,具有第一通孔的阀体和连接到阀体并具有第二通孔的保持体。 阀体具有阀座和用于引导阀针的第一引导区域,阀针设置在阀体中和保持体中,并且第一通孔形成在阀体中而没有被切削。

    METHOD FOR PRODUCING A DRUG DELIVERY SYSTEM ON THE BASIS OF POLYELECTROLYTE COMPLEXES
    7.
    发明申请
    METHOD FOR PRODUCING A DRUG DELIVERY SYSTEM ON THE BASIS OF POLYELECTROLYTE COMPLEXES 有权
    基于聚电解质复合物生产药物输送系统的方法

    公开(公告)号:US20130108774A1

    公开(公告)日:2013-05-02

    申请号:US13638413

    申请日:2011-03-30

    申请人: Martin Mueller

    发明人: Martin Mueller

    IPC分类号: A61J3/00

    摘要: The invention relates to the fields of polymer chemistry, pharmacy and medicine and relates to a method, which for example releases drugs as a component of implants into the environment of the implant. The object of the present invention is to disclose a method which in a simple and easily reproducible manner generates a drug delivery system, which releases drugs in a locally targeted and controllably delayed manner. The object is attained by a method in which polyanions and polycations are mixed in a liquid in a non-stoichiometric ratio, relative to the charged monomer units, wherein drugs are added to the polyelectrolytes either before, during or after the mixing, or charge-carrying drugs and an oppositely charged polyelectrolyte are mixed, and after the mixing the polyelectrolyte complex produced is applied to the surface of a medical means or is positioned on the surface directly at the location where the drug is to be released.

    摘要翻译: 本发明涉及聚合物化学,药学和药物的领域,涉及一种方法,例如将作为植入物的组分的药物释放到植入物的环境中。 本发明的目的是公开一种以简单且容易重现的方式产生药物递送系统的方法,药物递送系统以局部目标和可控地延迟的方式释放药物。 该目的通过一种方法实现,其中聚阴离子和聚阳离子相对于带电单体单元以非化学计量比混合在液体中,其中在混合之前,期间或之后将药物加入到聚电解质中, 将药物和相反电荷的聚电解质混合,并且混合后,所生产的聚电解质复合物被施加到医疗装置的表面,或者直接位于待释放药物的位置的表面上。

    View Life Cycle Management
    8.
    发明申请
    View Life Cycle Management 有权
    查看生命周期管理

    公开(公告)号:US20120143848A1

    公开(公告)日:2012-06-07

    申请号:US12962586

    申请日:2010-12-07

    IPC分类号: G06F17/30

    CPC分类号: G06F17/30383

    摘要: In one aspect, there is provided a method. The method may include generating a view of a data structure comprising a plurality of nodes and at least one association; determining, at run time, whether the generated view is invalid based on an indicator, the indicator representing at least whether a change has occurred to a system including the view; and deleting, at run time, the view based on the results of determining. Related apparatus, systems, techniques and articles are also described.

    摘要翻译: 一方面,提供了一种方法。 该方法可以包括生成包括多个节点和至少一个关联的数据结构的视图; 在运行时确定所生成的视图是否基于指示符无效,所述指示符至少表示对包括视图的系统是否已经发生改变; 并在运行时根据确定结果删除视图。 还描述了相关设备,系统,技术和物品。

    Damping element for a fuel injection valve
    10.
    发明申请
    Damping element for a fuel injection valve 有权
    燃油喷射阀阻尼元件

    公开(公告)号:US20090071445A1

    公开(公告)日:2009-03-19

    申请号:US11665040

    申请日:2005-09-08

    IPC分类号: F02M61/14

    摘要: Known damping elements (25) for a fuel injection valve (1) insertable into a receiving conduit (2) of a cylinder head (3) of an internal combustion engine are disposed between a valve housing (14) of the fuel injection valve (1) and a wall of the receiving conduit (2) of the cylinder head (3). These damping elements (25), inter alia, decrease acoustic transfer from the fuel injection valve to the cylinder head (3). It is disadvantageous that the damping elements known hitherto require a great deal of axial installation space with respect to a valve axis and have comparatively high manufacturing costs. With the damping element (25) according to the present invention, the installation space required is reduced. Provision is made, according to the present invention, for the damping element (25) to be in plate-shaped fashion.

    摘要翻译: 用于可插入内燃机的气缸盖(3)的接收管道(2)中的燃料喷射阀(1)的已知阻尼元件(25)设置在燃料喷射阀(1)的阀壳体(14) )和气缸盖(3)的接收管道(2)的壁。 这些阻尼元件(25)尤其降低了从燃料喷射阀到气缸盖(3)的声传递。 迄今为止已知的阻尼元件相对于阀轴线需要大量的轴向安装空间并且具有相对较高的制造成本是不利的。 利用根据本发明的阻尼元件(25),减少了所需的安装空间。 根据本发明,将阻尼元件(25)设计成板状。