公开(公告)号：US5494043A

公开(公告)日：1996-02-27

申请号：US59425

申请日：1993-05-04

申请人： Martin O'Sullivan ,  Lawrence W. Brendlen, Jr. ,  Donald Q. Dong ,  Jeffrey M. Moser ,  Kenneth H. Mollenauer ,  Kenneth C. Kitlas ,  William J. Kaspari

发明人： Martin O'Sullivan ,  Lawrence W. Brendlen, Jr. ,  Donald Q. Dong ,  Jeffrey M. Moser ,  Kenneth H. Mollenauer ,  Kenneth C. Kitlas ,  William J. Kaspari

IPC分类号： A61B5/021 ,  A61B5/024

CPC分类号： A61B5/02208 ,  A61B5/02233 ,  A61B5/7214 ,  A61B2560/0223 ,  A61B2562/0247

摘要： A sensor that utilizes strips of piezoelectric material to noninvasively measure the surface force/displacement resulting from a blood pressure wave traveling through an artery and transmitted through the arterial wall and overlying tissue, while canceling noise artifact signals is disclosed. Piezoelectric elements create an electrical signal when pressure is applied to their surface. In the preferred embodiment, the sensor is constructed so that there are three sensing elements--a signal sensing element in the center and one noise sensing element on each side of the center element. The center element is placed over an individuals artery, e.g., the radial artery in a persons wrist. When positioned this way, the two noise sensing elements are positioned on each side of the artery.The center element generates a signal that is a function of the pressure wave in the artery, whereas this signal is highly attenuated in the noise sensing elements. However, all three elements detect the noise artifact signals in the general area of the sensor. The area of the noise elements, when combined, is equal to that of the center element. This provides an average of the noise detected by the center element.The signals from the two noise sensing elements are subtracted from the center element signal, thereby canceling the noise in the center element.Also disclosed is a unique method that allows repositioning of the sensor after it has been attached to the patient, a mechanism for maintaining the appropriate hold down pressure, a wrist stabilization device for stabilizing the wrist during monitoring of the blood pressure. The present invention also allows blood pressure calibrations to be obtained using the wrist and arm stabilizer assembly.

摘要翻译： 公开了一种使用压电材料条的传感器来非侵入性地测量由通过动脉行进并通过动脉壁和上覆组织传播的血压波所产生的表面力/位移，同时消除噪声伪像信号。 当压力施加到其表面时，压电元件产生电信号。 在优选实施例中，传感器被构造成使得存在三个感测元件 - 中心处的信号感测元件和在中心元件的每一侧上的一个噪声感测元件。 中心元件放置在个体动脉上，例如人手腕中的桡动脉。 当以这种方式定位时，两个噪声感测元件位于动脉的每一侧。 中心元件产生一个信号，该信号是动脉中的压力波的函数，而该信号在噪声感测元件中被高度衰减。 然而，所有三个元件都检测传感器的一般区域中的噪声伪像信号。 当组合时，噪声元件的面积等于中心元件的面积。 这提供了由中心元件检测到的噪声的平均值。 来自两个噪声感测元件的信号从中心元件信号中减去，从而消除中心元件中的噪声。 还公开了一种独特的方法，其允许传感器在其被附接到患者之后重新定位，用于维持适当的压下压力的机构，用于在监测血压期间稳定手腕的手腕稳定装置。 本发明还允许使用手腕和手臂稳定器组件获得血压校准。

公开(公告)号：US20070106287A1

公开(公告)日：2007-05-10

申请号：US11236278

申请日：2005-09-26

申请人： Martin O'Sullivan

发明人： Martin O'Sullivan

IPC分类号： A61B18/18 ,  A61N1/00 ,  A61B5/05

CPC分类号： A61N1/04 ,  A61B18/1206 ,  A61B18/1492 ,  A61B34/20 ,  A61B2018/00351 ,  A61B2018/00779 ,  A61B2018/00839 ,  A61B2018/00869 ,  A61B2018/00875 ,  A61B2034/2051 ,  A61B2090/061 ,  A61N1/00 ,  A61N1/0517

摘要： A system and method for determining on a continuous, real-time basis the proximity of the esophagus to an endocardial catheter during mapping, ablation or other endocardial catheter-based procedures, comprising an esophagus probe catheter and an endocardial catheter adapted for proximal signal transmission between each other. A signal processing unit is included to process and compare a characteristic of the proximity signal that is changes or attenuates with distance between the two catheters, such as impedance, amplitude and/or phase. Audio and/or optical outputs are provided to alert an operator when the distance between the catheters changes or is below a baseline measurement to avoid damage to the esophagus by the endocardial catheter. The system and method may include adaptations of the catheters with location sensor, and a mapping/navigational system for nonfluoroscopic location determination of the catheters.

摘要翻译： 一种系统和方法，用于在映射，消融或其它基于心内膜导管的过程期间连续地实时地确定食管与心内膜导管的接近度，包括食管探针导管和心内膜导管，其适于在 彼此。 包括信号处理单元以处理和比较随着两个导管之间的距离（例如阻抗，幅度和/或相位）而改变或衰减的接近信号的特性。 提供音频和/或光学输出以在导管之间的距离改变或低于基线测量时提醒操作者，以避免心内膜导管损伤食道。 该系统和方法可以包括导管与位置传感器的适应，以及用于导管的非氟化位置确定的映射/导航系统。

公开(公告)号：US07155270B2

公开(公告)日：2006-12-26

申请号：US10692714

申请日：2003-10-24

申请人： Mario A. Solis ,  Richard Bautista ,  Robert F. Ocariz ,  James K. Lee ,  Martin O'Sullivan

发明人： Mario A. Solis ,  Richard Bautista ,  Robert F. Ocariz ,  James K. Lee ,  Martin O'Sullivan

IPC分类号： A61B5/042 ,  A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/1477 ,  A61B90/39 ,  A61B2017/00867 ,  A61B2018/00083 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1497 ,  A61B2034/2051 ,  A61B2218/002

摘要： A catheter that is particularly useful for simultaneously mapping multiple points within the heart is provided. The catheter includes a mapping assembly including a plurality of flexible spines, each having a free distal end. The spines are supported by an improved support structure that permits the spines to be more precisely arranged relative to one another. The catheter comprises an elongated catheter body. A mapping assembly is provided at the distal end of the catheter body. The mapping assembly comprises a support structure having a generally cylindrical base mounted on the distal end of the catheter body, the base having proximal and distal ends. The support structure further comprises at least two pre-shaped flexible support arms. Each support arm has a proximal end attached to the distal end of the generally cylindrical base and a free distal end. At least two non-conductive coverings are provided, each in surrounding relation to a corresponding one of the at least two support arms. At least one electrode is mounted over each of the at least two non-conductive coverings.

摘要翻译： 提供了一种特别有用的用于同时映射心脏内的多个点的导管。 该导管包括一个映射组件，其包括多个柔性刺，每个具有自由远端。 脊柱由改进的支撑结构支撑，其允许脊柱相对于彼此更精确地布置。 导管包括细长的导管体。 在导管主体的远端设有一个映射组件。 映射组件包括支撑结构，该支撑结构具有安装在导管主体的远端上的大致圆柱形基座，该基部具有近端和远端。 支撑结构还包括至少两个预成形的柔性支撑臂。 每个支撑臂具有附接到大致圆柱形基部的远端的近端和自由远端。 提供至少两个不导电覆盖物，每个至少两个不导电覆盖物围绕所述至少两个支撑臂中相应的一个。 至少一个电极安装在至少两个非导电覆盖层中的每一个上。

公开(公告)号：US09468494B2

公开(公告)日：2016-10-18

申请号：US11323057

申请日：2005-12-30

申请人： Martin O'Sullivan ,  James K. Lee ,  Irma Hill

发明人： Martin O'Sullivan ,  James K. Lee ,  Irma Hill

IPC分类号： A61B18/14 ,  B29C33/52 ,  B29C41/10 ,  C08G73/10 ,  A61B5/042 ,  A61B18/00 ,  A61B17/00 ,  A61M25/10 ,  B29C33/38 ,  B29C35/08 ,  B29C41/14 ,  B29C67/00 ,  B29L31/00

CPC分类号： A61B18/1492 ,  A61B5/0422 ,  A61B2017/00243 ,  A61B2018/00065 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00797 ,  A61B2018/00839 ,  A61B2018/1407 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2218/002 ,  A61M25/1027 ,  A61M25/1029 ,  A61M25/1038 ,  B29C33/3842 ,  B29C33/52 ,  B29C35/08 ,  B29C41/10 ,  B29C41/14 ,  B29C64/00 ,  B29C2033/525 ,  B29C2035/0827 ,  B29L2031/7542 ,  C08G73/10

摘要： A catheter for ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body having proximal and distal ends. An electrode assembly is provided at the distal end of the catheter body. The electrode assembly including a porous electrode arrangement that is generally transverse to the catheter body. The porous electrode arrangement comprises one or more electrodes electrically connected to a suitable energy source and a porous sleeve mounted in surrounding relation to the one or more electrodes and defining an open space between the porous sleeve and the one more electrodes. One or more irrigation openings fluidly connect the open space to a lumen extending through the catheter through which fluid can pass. In use, fluid passes through the lumen in the catheter, through the one or more irrigation openings, into the open space and through the porous sleeve.

公开(公告)号：US20050090729A1

公开(公告)日：2005-04-28

申请号：US10692714

申请日：2003-10-24

申请人： Mario Solis ,  Richard Bautista ,  Robert Ocariz ,  James Lee ,  Martin O'Sullivan

发明人： Mario Solis ,  Richard Bautista ,  Robert Ocariz ,  James Lee ,  Martin O'Sullivan

IPC分类号： A61B5/0408 ,  A61B5/04 ,  A61B5/0478 ,  A61B5/0492 ,  A61B17/00 ,  A61B18/14 ,  A61B19/00 ,  A61F2/00

CPC分类号： A61B18/1492 ,  A61B18/1477 ,  A61B90/39 ,  A61B2017/00867 ,  A61B2018/00083 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1497 ,  A61B2034/2051 ,  A61B2218/002

摘要： A catheter that is particularly useful for simultaneously mapping multiple points within the heart is provided. The catheter includes a mapping assembly including a plurality of flexible spines, each having a free distal end. The spines are supported by an improved support structure that permits the spines to be more precisely arranged relative to one another. The catheter comprises an elongated catheter body. A mapping assembly is provided at the distal end of the catheter body. The mapping assembly comprises a support structure having a generally cylindrical base mounted on the distal end of the catheter body, the base having proximal and distal ends. The support structure further comprises at least two pre-shaped flexible support arms. Each support arm has a proximal end attached to the distal end of the generally cylindrical base and a free distal end. At least two non-conductive coverings are provided, each in surrounding relation to a corresponding one of the at least two support arms. At least one electrode is mounted over each of the at least two non-conductive coverings.

摘要翻译： 提供了一种特别有用的用于同时映射心脏内的多个点的导管。 该导管包括一个映射组件，其包括多个柔性刺，每个具有自由远端。 脊柱由改进的支撑结构支撑，其允许脊柱相对于彼此更精确地布置。 导管包括细长的导管体。 在导管主体的远端设有一个映射组件。 映射组件包括支撑结构，该支撑结构具有安装在导管主体的远端上的大致圆柱形基座，该基部具有近端和远端。 支撑结构还包括至少两个预成形的柔性支撑臂。 每个支撑臂具有附接到大致圆柱形基部的远端的近端和自由远端。 提供至少两个不导电覆盖物，每个至少两个不导电覆盖物围绕所述至少两个支撑臂中相应的一个。 至少一个电极安装在至少两个非导电覆盖层中的每一个上。

公开(公告)号：US20050015082A1

公开(公告)日：2005-01-20

申请号：US10622221

申请日：2003-07-18

申请人： Martin O'Sullivan ,  James Lee ,  Irma Hill

发明人： Martin O'Sullivan ,  James Lee ,  Irma Hill

IPC分类号： A61B5/042 ,  A61B17/00 ,  A61B18/14

CPC分类号： A61B5/0422 ,  A61B18/1492 ,  A61B2017/00243 ,  A61B2018/00065 ,  A61B2018/00839 ,  A61B2018/1472

摘要： A catheter for ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body having proximal and distal ends. An electrode assembly is provided at the distal end of the catheter body. The electrode assembly including a porous electrode arrangement that is generally transverse to the catheter body. The porous electrode arrangement comprises one or more electrodes electrically connected to a suitable energy source and a porous sleeve mounted in surrounding relation to the one or more electrodes and defining an open space between the porous sleeve and the one more electrodes. One or more irrigation openings fluidly connect the open space to a lumen extending through the catheter through which fluid can pass. In use, fluid passes through the lumen in the catheter, through the one or more irrigation openings, into the open space and through the porous sleeve.

摘要翻译： 提供用于消融组织的导管。 导管包括具有近端和远端的细长的大致管状的导管体。 电极组件设置在导管主体的远端。 电极组件包括通常横向于导管主体的多孔电极装置。 多孔电极装置包括电连接到合适能量源的一个或多个电极和围绕一个或多个电极安装的多孔套筒，并且在多孔套管和多个电极之间限定开放空间。 一个或多个冲洗开口将开放空间流体地连接到延伸穿过导管的内腔，流体可以通过该腔。 在使用中，流体通过导管中的内腔通过一个或多个冲洗开口进入开放空间并穿过多孔套管。

公开(公告)号：US20070135810A1

公开(公告)日：2007-06-14

申请号：US11654116

申请日：2007-01-16

申请人： James Lee ,  Martin O'Sullivan ,  Irma Hill

发明人： James Lee ,  Martin O'Sullivan ,  Irma Hill

IPC分类号： A61B18/14

CPC分类号： A61B5/0422 ,  A61B5/01 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2017/00867 ,  A61B2018/00839

摘要： A catheter for measuring electrical activity and ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body. A non-retractable electrode assembly is mounted at the distal end of the catheter body. The electrode assembly comprises a generally tubular ablation electrode formed of a material having shape-memory having a generally straight exposed region and at least one irrigation port in the exposed region through which fluid can pass from the inside to the outside of the ablation electrode. The exposed region is generally transverse to the catheter body. The electrode assembly further comprises a tip at the distal end of the electrode assembly comprising a generally ball-shaped exposed region. First and second distal mapping electrodes are mounted distal to the exposed region of the ablation electrode. At least the first distal mapping electrode, and optionally the second distal mapping electrode, is incorporated into the generally ball-shaped exposed region of the tip. The catheter further comprises an infusion tube extending through the catheter body and having a distal end in fluid communication with the proximal end of the ablation electrode.

摘要翻译： 提供了一种用于测量电活动和消融组织的导管。 导管包括细长的大致管状导管体。 不可伸缩的电极组件安装在导管主体的远端。 电极组件包括由具有形状记忆体的材料形成的大体上管状的消融电极，该材料具有大致直的暴露区域和暴露区域中的至少一个冲洗口，流体可以通过该至少一个冲洗口从消融电极的内部传递到外部。 暴露区域通常横向于导管体。 电极组件还包括在电极组件的远端处的尖端，其包括大致球形的暴露区域。 第一和第二远端测绘电极安装在消融电极的暴露区域的远侧。 至少第一远端测绘电极和任选地第二远端映射电极被并入尖端的大致球形的暴露区域中。 导管还包括延伸穿过导管主体并具有与消融电极的近端流体连通的远端的输注管。

公开(公告)号：US07163537B2

公开(公告)日：2007-01-16

申请号：US10452103

申请日：2003-06-02

申请人： James K. Lee ,  Martin O'Sullivan ,  Irma Hill

发明人： James K. Lee ,  Martin O'Sullivan ,  Irma Hill

IPC分类号： A61B18/18 ,  A61F7/00

CPC分类号： A61B5/0422 ,  A61B5/01 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2017/00867 ,  A61B2018/00839

摘要： A catheter for measuring electrical activity and ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body. A non-retractable electrode assembly is mounted at the distal end of the catheter body. The electrode assembly comprises a generally tubular ablation electrode formed of a material having shape-memory having a generally straight exposed region and at least one irrigation port in the exposed region through which fluid can pass from the inside to the outside of the ablation electrode. The exposed region is generally transverse to the catheter body. The electrode assembly further comprises a tip at the distal end of the electrode assembly comprising a generally ball-shaped exposed region. First and second distal mapping electrodes are mounted distal to the exposed region of the ablation electrode. At least the first distal mapping electrode, and optionally the second distal mapping electrode, is incorporated into the generally ball-shaped exposed region of the tip. The catheter further comprises an infusion tube extending through the catheter body and having a distal end in fluid communication with the proximal end of the ablation electrode.

公开(公告)号：US10182734B2

公开(公告)日：2019-01-22

申请号：US10622221

申请日：2003-07-18

申请人： Martin O'Sullivan ,  James K. Lee ,  Irma Hill

发明人： Martin O'Sullivan ,  James K. Lee ,  Irma Hill

IPC分类号： A61B17/00 ,  A61B5/042 ,  A61B18/14 ,  A61B18/00

摘要： A catheter for ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body having proximal and distal ends. An electrode assembly is provided at the distal end of the catheter body. The electrode assembly including a porous electrode arrangement that is generally transverse to the catheter body. The porous electrode arrangement comprises one or more electrodes electrically connected to a suitable energy source and a porous sleeve mounted in surrounding relation to the one or more electrodes and defining an open space between the porous sleeve and the one more electrodes. One or more irrigation openings fluidly connect the open space to a lumen extending through the catheter through which fluid can pass. In use, fluid passes through the lumen in the catheter, through the one or more irrigation openings, into the open space and through the porous sleeve.

公开(公告)号：US08133220B2

公开(公告)日：2012-03-13

申请号：US11654116

申请日：2007-01-16

申请人： James K. Lee ,  Martin O'Sullivan ,  Irma Hill

发明人： James K. Lee ,  Martin O'Sullivan ,  Irma Hill

IPC分类号： A61B18/14

CPC分类号： A61B5/0422 ,  A61B5/01 ,  A61B18/1492 ,  A61B2017/00053 ,  A61B2017/00867 ,  A61B2018/00839

摘要： A catheter for measuring electrical activity and ablating tissue is provided. The catheter comprises an elongated generally-tubular catheter body. A non-retractable electrode assembly is mounted at the distal end of the catheter body. The electrode assembly comprises a generally tubular ablation electrode formed of a material having shape-memory having a generally straight exposed region and at least one irrigation port in the exposed region through which fluid can pass from the inside to the outside of the ablation electrode. The exposed region is generally transverse to the catheter body. The electrode assembly further comprises a tip at the distal end of the electrode assembly comprising a generally ball-shaped exposed region. First and second distal mapping electrodes are mounted distal to the exposed region of the ablation electrode. At least the first distal mapping electrode, and optionally the second distal mapping electrode, is incorporated into the generally ball-shaped exposed region of the tip. The catheter further comprises an infusion tube extending through the catheter body and having a distal end in fluid communication with the proximal end of the ablation electrode.

摘要翻译： 提供了一种用于测量电活动和消融组织的导管。 导管包括细长的大致管状导管体。 不可伸缩的电极组件安装在导管主体的远端。 电极组件包括由具有形状记忆体的材料形成的大体上管状的消融电极，该材料具有大致直的暴露区域和暴露区域中的至少一个冲洗口，流体可以通过该至少一个冲洗口从消融电极的内部传递到外部。 暴露区域通常横向于导管体。 电极组件还包括在电极组件的远端处的尖端，其包括大致球形的暴露区域。 第一和第二远端测绘电极安装在消融电极的暴露区域的远侧。 至少第一远端测绘电极和任选地第二远端映射电极被并入尖端的大致球形的暴露区域中。 导管还包括延伸穿过导管主体并具有与消融电极的近端流体连通的远端的输注管。