公开(公告)号：US20080199524A1

公开(公告)日：2008-08-21

申请号：US11810524

申请日：2007-06-06

申请人： Masahiro Inohara ,  Masahito Yoshikawa ,  Takashi Taniguchi ,  Mitsuru Yokota ,  Naoki Shimoyama ,  Masaki Ue ,  Miho Araki ,  Yukiko Sugihara ,  Yoshihide Horibe ,  Mitsuaki Kuwano

发明人： Masahiro Inohara ,  Masahito Yoshikawa ,  Takashi Taniguchi ,  Mitsuru Yokota ,  Naoki Shimoyama ,  Masaki Ue ,  Miho Araki ,  Yukiko Sugihara ,  Yoshihide Horibe ,  Mitsuaki Kuwano

IPC分类号： A61K9/14

CPC分类号： A61K9/0048 ,  A61K9/08

摘要： It is intended to prepare a composition which contains polysaccharide at a high concentration and yet remains in the state of a liquid having low viscosity to thereby provide drugs, eyedrops, foods, cosmetics, toiletry products having a novel texture or function. The composition in the state of a liquid having low viscosity is obtained by heating polysaccharide at a high concentration in a water-containing liquid and then cooling under applying a shear force, which enables the provision of the above-described drugs. The composition is usable as an aqueous drug vehicle which is free from gelling due to temperature changes during storage and easily applied without pouring and/or streaming down. Eyedrops containing agar have an effect of enhancing ocular drug penetration. Eyedrops containing particulate agar maintain a low viscosity and, achieve easy instillation and impart a favorable feel in instillation.

摘要翻译： 本发明的目的在于制备含有高浓度多糖但仍具有低粘度的液体状态的组合物，从而提供具有新颖的质地或功能的药物，滴眼剂，食品，化妆品，化妆品等。 通过在含水液体中以高浓度加热多糖，然后在施加剪切力的条件下冷却，得到具有低粘度的液体状态的组合物，从而能够提供上述药物。 该组合物可用作水性药物载体，其由于储存期间的温度变化而没有胶凝，并且容易施用而没有倾倒和/或流下。 含有琼脂的滴眼液具有增强眼药物渗透的作用。 含有颗粒状琼脂的喷雾剂保持低粘度，并且实现容易滴注并赋予滴注有利的感觉。

公开(公告)号：US20100317615A1

公开(公告)日：2010-12-16

申请号：US12806550

申请日：2010-08-16

申请人： Masahiro Inohara ,  Masahito Yoshikawa ,  Takashi Taniguchi ,  Mitsuru Yokota ,  Naoki Shimoyama ,  Masaki Ue ,  Miho Araki

发明人： Masahiro Inohara ,  Masahito Yoshikawa ,  Takashi Taniguchi ,  Mitsuru Yokota ,  Naoki Shimoyama ,  Masaki Ue ,  Miho Araki

IPC分类号： A61K31/729 ,  A61P27/02

CPC分类号： A61K9/0048 ,  A61K9/08

摘要： A method of enhancing ocular penetration of a drug in an eyedrop by administering to an eye, an eyedrop containing, particulate agar having a weight-average molecular weight of from 5,000 to 1,200,000, the particulate agar being obtained by dissolving agar into an aqueous solution by heating and then cooling the resultant mixture to avoid gelling, while applying a stress by vibration, shearing, stirring, compression or pulverizing, wherein the particulate agar is in an amount of 0.1 to 10 wt %.

摘要翻译： 通过向眼睛施用含有重均分子量为5,000至1,200,000的含有滴眼剂的颗粒状琼脂的眼睛，通过将琼脂溶解在水溶液中而获得的颗粒状琼脂通过 加热，然后冷却所得混合物以避免胶凝，同时通过振动，剪切，搅拌，压缩或粉碎施加应力，其中颗粒状琼脂的量为0.1至10重量％。

公开(公告)号：US08314192B2

公开(公告)日：2012-11-20

申请号：US12375371

申请日：2006-07-28

申请人： Norikazu Tabata ,  Kazuhiko Hashisaka ,  Masahiro Sugimura ,  Takuo Sakamoto ,  Masaki Ue ,  Hiroyuki Nakayama ,  Seiji Fukuda

发明人： Norikazu Tabata ,  Kazuhiko Hashisaka ,  Masahiro Sugimura ,  Takuo Sakamoto ,  Masaki Ue ,  Hiroyuki Nakayama ,  Seiji Fukuda

IPC分类号： C08F2/00

CPC分类号： B24B37/24 ,  B24D18/0027 ,  C08F2/38 ,  C08F2/40 ,  C08F265/04 ,  C08F283/00 ,  C08J3/246 ,  C08L33/10 ,  C08L75/00 ,  C08L2205/04 ,  C08L75/04

摘要： The present invention relates to a process for producing an interpenetrating polymer network structure, which comprises the steps of impregnating a polymer molding with a radical polymerizable composition containing an ethylenically unsaturated compound and a radical polymerization initiator; and polymerizing the ethylenically unsaturated compound in a swollen state of the polymer molding impregnated with the radical polymerizable composition; wherein a chain transfer agent and/or a radical polymerization inhibitor are added to the radical polymerizable composition and/or the polymer molding before impregnating the polymer molding with the radical polymerizable composition. According to the present invention, a highly uniform interpenetrating polymer network structure can be obtained. The present invention also provides a polishing pad which is exhibits high in-plane uniformity of a polishing rate during polishing, and also has excellent flattening properties and improved pad lifetime during polishing, and a process for producing the same.

摘要翻译： 本发明涉及一种互穿聚合物网状结构体的制造方法，其特征在于，包括使含有烯键式不饱和化合物和自由基聚合引发剂的自由基聚合性组合物浸渍聚合物成型体的工序; 并在浸渍有自由基聚合性组合物的聚合物成型体的溶胀状态下聚合烯属不饱和化合物; 其中在用可自由基聚合的组合物浸渍聚合物模制品之前，将链转移剂和/或自由基聚合抑制剂加入到可自由基聚合的组合物和/或聚合物模制品中。 根据本发明，可以获得高度均匀的互穿聚合物网络结构。 本发明还提供一种研磨抛光时的研磨速度平面均匀性高的抛光垫，并且还具有优异的平坦化性能和抛光时的垫寿命的改善及其制造方法。

公开(公告)号：US20090280723A1

公开(公告)日：2009-11-12

申请号：US12375371

申请日：2006-07-28

申请人： Norikazu Tabata ,  Kazuhiko Hashisaka ,  Masahiro Sugimura ,  Takuo Sakamoto ,  Masaki Ue ,  Hiroyuki Nakayama ,  Seiji Fukuda

发明人： Norikazu Tabata ,  Kazuhiko Hashisaka ,  Masahiro Sugimura ,  Takuo Sakamoto ,  Masaki Ue ,  Hiroyuki Nakayama ,  Seiji Fukuda

IPC分类号： B24B1/00 ,  C08G18/00 ,  C09K3/14 ,  B24D3/32 ,  B24D7/00

CPC分类号： B24B37/24 ,  B24D18/0027 ,  C08F2/38 ,  C08F2/40 ,  C08F265/04 ,  C08F283/00 ,  C08J3/246 ,  C08L33/10 ,  C08L75/00 ,  C08L2205/04 ,  C08L75/04

摘要： The present invention relates to a process for producing an interpenetrating polymer network structure, which comprises the steps of impregnating a polymer molding with a radical polymerizable composition containing an ethylenically unsaturated compound and a radical polymerization initiator; and polymerizing the ethylenically unsaturated compound in a swollen state of the polymer molding impregnated with the radical polymerizable composition; wherein a chain transfer agent and/or a radical polymerization inhibitor are added to the radical polymerizable composition and/or the polymer molding before impregnating the polymer molding with the radical polymerizable composition. According to the present invention, a highly uniform interpenetrating polymer network structure can be obtained. The present invention also provides a polishing pad which is exhibits high in-plane uniformity of a polishing rate during polishing, and also has excellent flattening properties and improved pad lifetime during polishing, and a process for producing the same.

摘要翻译： 本发明涉及一种互穿聚合物网状结构体的制造方法，其特征在于，包括使含有烯键式不饱和化合物和自由基聚合引发剂的自由基聚合性组合物浸渍聚合物成型体的工序; 并在浸渍有自由基聚合性组合物的聚合物成型体的溶胀状态下聚合烯属不饱和化合物; 其中在用可自由基聚合的组合物浸渍聚合物模制品之前，将链转移剂和/或自由基聚合抑制剂加入到可自由基聚合的组合物和/或聚合物模制品中。 根据本发明，可以获得高度均匀的互穿聚合物网络结构。 本发明还提供一种研磨抛光时的研磨速度平面均匀性高的抛光垫，并且还具有优异的平坦化性能和抛光时的垫寿命的改善及其制造方法。