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    Decarbamylase isolated from comamonas or blastobacter
    3.
    发明授权
    Decarbamylase isolated from comamonas or blastobacter 失效
    从comamonas或blastobacter分离的脱氨基甲酰酶

    公开(公告)号：US5863785A

    公开(公告)日：1999-01-26

    申请号：US479639

    申请日：1995-06-07

    申请人： Hideaki Yamada ,  Sakayu Shimizu ,  Yasuhiro Ikenaka ,  Kazuyoshi Yajima ,  Yukio Yamada ,  Hirokazu Nanba ,  Masayuki Takano ,  Satomi Takahashi

    发明人： Hideaki Yamada ,  Sakayu Shimizu ,  Yasuhiro Ikenaka ,  Kazuyoshi Yajima ,  Yukio Yamada ,  Hirokazu Nanba ,  Masayuki Takano ,  Satomi Takahashi

    IPC分类号： C12P13/04 ,  C12P41/00 ,  C12N9/78 ,  C12N9/80

    CPC分类号： C12P13/04 ,  C12P41/009 ,  Y10S435/874 ,  Y10S435/911

    摘要： In a process for the production of a D-.alpha.-amino acid, in which an N-carbamyl-D-.alpha.-amino acid corresponding to the general formula: ##STR1## wherein R represents phenyl, hydroxy-substituted phenyl, substituted or unsubstituted alkyl, or thienyl, is converted by a microbial enzyme in an aqueous medium to a D-.alpha.-amino acid corresponding to the general formula: ##STR2## wherein R is the same as defined above, decarbamylase produced by a microorganism of the genus Comamonas, Blastobacter, Alcaligenes, Sporosarcina, Rhizobium, Bradyrhizobium or Arthrobacter is used as the enzyme converting the N-carbamyl-D-.alpha.-amino acid to the D-.alpha.-amino acid.The conversion of the N-carbamyl-D-.alpha.-amino acids to the D-.alpha.-amino acids is carried out in a neutral to alkaline pH range.

    摘要翻译： 在制备D-α-氨基酸的方法中，其中相应于通式为：苯基，取代或未取代的烷基或噻吩基的N-氨基甲酰基-D-α-氨基酸被转化 通过微生物酶在水性介质中与对应于以下通式的D-α-氨基酸反应：其中R与上述定义相同，由Comamonas属，Blastobacter，Alcaligenes，Sporosarcina属的微生物产生的脱氨基甲酰酶， 使用根瘤菌，Bradyrhizobium或节杆菌作为将N-氨基甲酰基-D-α-氨基酸转化为D-α-氨基酸的酶。 N-氨基甲酰基-D-α-氨基酸向D-α-氨基酸的转化在中性至碱性pH范围内进行。

    Blower
    4.
    发明授权
    Blower 有权
    鼓风机

    公开(公告)号：US08745815B2

    公开(公告)日：2014-06-10

    申请号：US13372665

    申请日：2012-02-14

    申请人： Masayuki Takano ,  Takeshi Maeno

    发明人： Masayuki Takano ,  Takeshi Maeno

    IPC分类号： A47L5/24 ,  F04D25/08

    CPC分类号： F04D25/084 ,  A01G20/43

    摘要： A handheld blower has a body including a combustion engine and a blower section driven by the combustion engine, and a handle coupled to the body. The blower section has an air outlet directed forward with respect to an operator. The handle has a grip portion extending in a front-back direction with respect to the operator, a front arm extending from a front portion of the grip portion to the body, and a rear arm extending from a rear portion of the grip portion to the body. The front arm and the rear arm are more flexible in the front-back direction than in directions perpendicular to the front-back direction.

    摘要翻译： 手持式鼓风机具有主体，其包括内燃机和由内燃机驱动的鼓风机部分，以及与主体相连的手柄。 鼓风机部分具有相对于操作者向前指示的出气口。 手柄具有相对于操作者在前后方向上延伸的抓握部分，从把手部分的前部延伸到主体的前臂以及从把手部分的后部延伸到主体的后臂 身体。 前臂和后臂在前后方向上比在垂直于前后方向的方向上更柔性。

    WORK MACHINE
    5.
    发明申请
    WORK MACHINE 失效
    工作机器

    公开(公告)号：US20090048743A1

    公开(公告)日：2009-02-19

    申请号：US12096829

    申请日：2006-08-29

    申请人： Eiji Akahane ,  Christopher Michael Burton ,  Nobumi Toyoura ,  Shigeru Kojima ,  Masayuki Takano

    发明人： Eiji Akahane ,  Christopher Michael Burton ,  Nobumi Toyoura ,  Shigeru Kojima ,  Masayuki Takano

    IPC分类号： G08B21/02 ,  G05G1/01 ,  G05G1/30 ,  B60Q1/00

    CPC分类号： E02F9/2004 ,  E02F9/2025 ,  Y10T74/20012 ,  Y10T74/20396 ,  Y10T74/20528 ,  Y10T74/2054

    摘要： To provide a work machine in which traveling devices and an implement device can be operated by common operating levers, wherein switching operation is easy and a changeover is easily confirmed. Inside a cab of the work machine, there are provided travel pedals, with which the traveling devices can be operated, and operating levers, with which the traveling devices and the implement device can be operated. A changeover switch is provided on a console positioned in the vicinity of one side of an operating sheet. The changeover switch switches over between a traveling mode, in which traveling operation is possible by the operating levers, and a work mode, in which implement operation is possible by the operating levers. The work machine has a controller which makes it possible to work by the operating levers when the travel pedal is not stepped on in the case where the work mode or traveling mode is selected by the changeover switch, and makes it possible to travel by the operating levers only when the travel pedal is stepped on in the case where the traveling mode is selected by the changeover switch.

    摘要翻译： 为了提供一种工作机械，其中行驶装置和工具装置可由普通操作杆操作，其中切换操作容易并且容易确认切换。 在作业机的驾驶室内设有可以操作行走装置的行驶踏板，以及可以操作行驶装置和工具装置的操作杆。 在位于操作片一侧附近的控制台上设置有切换开关。 切换开关在通过操作杆进行行驶操作的行驶模式和通过操作杆进行实施操作的作业模式之间切换。 作业机具有控制器，当通过切换开关选择工作模式或行驶模式的情况下，当行走踏板不踩踏时，能够通过操作杆进行操作，并且可以通过操作 只有在通过切换开关选择了行驶模式的情况下踏步踏板时，才能够进行操作。

    DNA coding for decarbamylase improved in thermostability and use thereof
    7.
    发明授权
    DNA coding for decarbamylase improved in thermostability and use thereof 失效
    编码脱氨基甲酰酶的DNA改善了热稳定性和使用

    公开(公告)号：US6083752A

    公开(公告)日：2000-07-04

    申请号：US876398

    申请日：1997-06-16

    申请人： Yasuhiro Ikenaka ,  Hirokazu Nanba ,  Masayuki Takano ,  Kazuyoshi Yajima ,  Yukio Yamada ,  Satomi Takahashi

    发明人： Yasuhiro Ikenaka ,  Hirokazu Nanba ,  Masayuki Takano ,  Kazuyoshi Yajima ,  Yukio Yamada ,  Satomi Takahashi

    IPC分类号： C12N9/80 ,  C12N15/55 ,  C12N15/72 ,  C12P13/06 ,  C12P13/08 ,  C12P13/22 ,  C12N15/00 ,  C12N5/10 ,  C12N9/14

    CPC分类号： C12N15/72 ,  C12N9/80 ,  C12P13/06 ,  C12P13/08 ,  C12P13/22

    摘要： A DNA fragment coding for a decarbamylase protein improved in thermostability as the result of replacement of at least one base of a DNA fragment coding for a decarbamylase protein derived from a microorganism with another base and the resultant replacement of at least one of the corresponding amino acids, and its production process; a vector containing the DNA fragment; a transformant obtained by transformation with the vector; as well as a decarbamylase improved in thermostability and its production process. Also disclosed is a process for producing a D-.alpha.-amino acid, which comprises converting an N-carbamoyl-D-.alpha.-amino acid into the corresponding D-.alpha.-amino acid in an aqueous medium by the action of a decarbamylase having a thermostable temperature of 65.degree. C. or higher; and collecting the D-.alpha.-amino acid produced.

    摘要翻译： 由于将来自微生物的脱氨基甲酰酶蛋白质的至少一个碱基替换为另一碱基的氨基酸残基的至少一个碱基，所以替代了至少一个相应的氨基酸 ，及其生产工艺; 含有DNA片段的载体; 通过用载体转化获得的转化体; 以及改进了热稳定性的脱氨基甲酰酶及其制备方法。 还公开了一种制备D-α-氨基酸的方法，该方法包括通过脱氨基甲酰酶的作用将N-氨基甲酰基-D-α-氨基酸转化成水性介质中的相应的D- 耐热温度在65℃以上; 并收集产生的D-α-氨基酸。

    Process for production of D-.alpha.-amino acids
    8.
    发明授权
    Process for production of D-.alpha.-amino acids 失效
    生产D-α-氨基酸的方法

    公开(公告)号：US5565344A

    公开(公告)日：1996-10-15

    申请号：US917111

    申请日：1992-08-07

    申请人： Hirokazu Nanba ,  Yukio Yamada ,  Masayuki Takano ,  Yasuhiro Ikenaka ,  Satomi Takahashi ,  Kazuyoshi Yajima

    发明人： Hirokazu Nanba ,  Yukio Yamada ,  Masayuki Takano ,  Yasuhiro Ikenaka ,  Satomi Takahashi ,  Kazuyoshi Yajima

    IPC分类号： C12N1/21 ,  C12N9/80 ,  C12N15/55 ,  C12P13/04 ,  C12P41/00 ,  C07H19/00 ,  C12N1/12 ,  C12N9/14

    CPC分类号： C12P41/009 ,  C12N9/80 ,  C12P13/04

    摘要： The present invention is directed to a gene which is related to a D-N-carbamoyl-.alpha.-amino acid amidohydrolase which is an enzyme capable of converting D-N-carbamoyl-.alpha.-amino acids into D-.alpha.-amino acids; a recombinant plasmid in which a DNA fragment containing the gene is incorporated into a vector; a microorganism belonging to the genus Escherichia, Pseudomonas, Flavobacterium, Bacillus, Serratia, Corynebacterium, or Brevibacterium, which is transformed by incorporating the recombinant plasmid thereinto; a process for the production of D-N-carbamoyl-.alpha.-amino acid amidohydrolases, comprising the steps of cultivating the transformed microorganism and collecting the desired product therefrom; a D-N-carbamoyl-.alpha.-amino acid amidohydrolase obtained by the method; and a process for the production of D-.alpha.-amino acids with the aid of an action of the enzyme.The D-N-carbamoyl-.alpha.-amino acid amidohydrolase can be fixed on a support for immobilization and used as an immobilized enzyme.

    摘要翻译： PCT No.PCT / JP91 / 01696 Sec。 371日期：1992年8月7日 102（e）日期1992年8月7日PCT 1991年12月6日PCT PCT。 出版物WO92 / 10579 日期1992年6月25日本发明涉及与能够将D-N-氨基甲酰基-α-氨基酸转化为D-氨基酸的酶的D-N-氨基甲酰基-α-氨基酸酰胺水解酶相关的基因。 将含有该基因的DNA片段并入载体的重组质粒; 通过将重组质粒并入而转化的属于埃希氏杆菌属，假单胞菌属，黄杆菌属，芽孢杆菌属，沙雷氏菌属，棒状杆菌属或短杆菌属的微生物; 制备D-N-氨基甲酰基-α-氨基酸酰胺水解酶的方法，包括培养转化的微生物并从其中收集所需产物的步骤; 通过该方法获得的D-N-氨基甲酰基-α-氨基酸酰胺水解酶; 以及借助于酶的作用生产D-氨基酸的方法。 D-N-氨基甲酰基-α-氨基酸酰胺水解酶可以固定在用于固定的载体上并用作固定化酶。

    Intracavitary ultrasound probe
    9.
    发明授权
    Intracavitary ultrasound probe 失效
    腔内超声探头

    公开(公告)号：US5090414A

    公开(公告)日：1992-02-25

    申请号：US396245

    申请日：1989-08-21

    申请人： Masayuki Takano

    发明人： Masayuki Takano

    IPC分类号： G01N29/26 ,  A61B8/12 ,  A61B17/34 ,  A61B17/435 ,  G10K11/35

    CPC分类号： A61B8/12 ,  A61B17/3403 ,  A61B17/435 ,  A61B8/445 ,  A61B8/4461 ,  G10K11/355 ,  A61B2017/3413

    摘要： An intracavitary ultrasound probe comprises a rotating shaft rotatably supported inside an elongated body and adapted to swing or rotate a transducer element, an motor housed in a handle, and a stab needle guide extending in substantially parallel to the elongated body. The motor is arranged in a manner to be offset from the rotating shaft, and the ultrasound probe further comprises a mechanism for transmitting torque from the motor to the rotating shaft. Since, therefore, the handle is offset from the elongated body, a wide space for operating a stab needle is provided, thus ensuring easy operation of the stab needle. In addition, a wide space for employing a syringe is also provided. As a result of this structure, the patient's pain is reduced, and the probe is easy to rotate or tilt.

    摘要翻译： 腔内超声探头包括旋转轴，其可旋转地支撑在细长主体内并且适于摆动或旋转换能器元件，容纳在手柄中的马达以及基本上平行于细长主体延伸的刺针引导件。 所述电动机以与所述旋转轴相抵的方式配置，所述超声波探头还具有将所述电动机的转矩传递给所述旋转轴的机构。 因此，由于把手从细长体偏移，所以设置有用于操作刺针的宽的空间，从而确保刺针的容易操作。 此外，还提供了用于使用注射器的宽广空间。 由于这种结构，患者的疼痛减轻，探头容易旋转或倾斜。

    Video tape editor
    10.
    发明授权
    Video tape editor 失效
    录像带编辑器

    公开(公告)号：US4463391A

    公开(公告)日：1984-07-31

    申请号：US306767

    申请日：1981-09-29

    申请人： Masayuki Takano ,  Masaaki Sakai ,  Masaharu Enoki

    发明人： Masayuki Takano ,  Masaaki Sakai ,  Masaharu Enoki

    IPC分类号： H04N5/7826 ,  G11B27/02 ,  G11B27/028 ,  G11B27/029 ,  H04N5/782 ,  G11B15/18

    CPC分类号： G11B27/028 ,  G11B27/029

    摘要： Insert and assemble editing of video signals are carried out using a VTR having helically scanning rotary record/playback heads. Following the recording of a first video signal in slant tracks on the tape, the tape is stopped at an edit point where recording of a second video signal is to commence. Then the tape is run reversely while control signals associated with the locations of the tracks are reproduced. These control signals are counted and the tape is stopped when a predetermined number of such signals have been counted. Thereafter the tape is advanced to a noiseless-still-picture position, based on a counted number of oscillations associated with rotation of the tape capstan, at which an acceptably noise-free picture is obtained, notwithstanding that the head scan of the rotary heads does not completely coincide with the slant tracks when the tape is stopped. After this, the tape is run at normal speed, and when the tape reaches the edit point, the VTR begins to record the second signal, which is at that time in step with the previously-recorded first video signal.

    摘要翻译： 使用具有螺旋扫描旋​​转记录/回放头的VTR来执行视频信号的插入和组合编辑。 在磁带上的倾斜轨道中记录第一视频信号之后，磁带停止在要开始第二视频信号的记录的编辑点。 然后磁带反向运行，同时再现与磁道位置相关联的控制信号。 这些控制信号被计数，并且当已经计数了预定数量的这种信号时磁带被停止。 此后，根据旋转磁头的头部扫描，即使获得可接受的无噪点的图像，也可以基于与带状主导体的旋转相关联的计数的振荡次数将磁带推进到无噪声静止图像位置 当磁带停止时，与斜面不完全一致。 之后，磁带以正常速度运行，并且当磁带到达编辑点时，VTR开始记录与之前记录的第一视频信号同步的第二信号。