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公开(公告)号：US20110312788A1
公开(公告)日：2011-12-22
申请号：US13150190
申请日：2011-06-01
IPC分类号： C40B60/12
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A lab-on-a-chip (LOC) device for genetic analysis having a supporting substrate, an array of probes for hybridization with target nucleic acid sequences to form probe-target hybrids, a channel for directing a flow of liquid containing the target nucleic acid sequences, the channel having an inlet, an outlet and a meniscus anchor between the inlet and the outlet such that the flow from the inlet towards the outlet stops at the meniscus anchor where the liquid forms a meniscus, and, an actuator valve with a valve heater for heating the meniscus such that the meniscus unpins from the meniscus anchor such that the liquid flow towards the outlet resumes.
摘要翻译： 用于具有支持底物的遗传分析实验室（LOC）装置，用于与靶核酸序列杂交以形成探针 - 靶杂交体的探针阵列，用于引导含有靶核酸的液体流的通道 通道在入口和出口之间具有入口，出口和弯液面锚固件，使得从入口朝向出口的流动停止在液体形成弯液面的弯液面锚固件处;以及致动器阀，其具有 用于加热弯液面的阀加热器，使得弯液面从弯液面锚固件脱开，使得朝向出口的液体流动恢复。
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2.发明申请MICROFLUIDIC DEVICE WITH ARRAY OF CHAMBERS AND CORRESPONDING DIFFUSION BARRIERS FOR ELECTROCHEMILUMINESCENT DETECTION OF TARGETS 审中-公开具有阵列阵列和对应扩散障碍物的微流控器件用于电致发光检测目标公开(公告)号：US20110312661A1
公开(公告)日：2011-12-22
申请号：US13149956
申请日：2011-06-01
IPC分类号： C40B60/12
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A microfluidic device for detecting target molecules in a fluid, the microfluidic device having an array of chambers, each containing electrochemiluminescent (ECL) probes for reaction with the target molecules to form a probe-target complex, and electrodes positioned in each of the chambers for receiving an electrical pulse, the probe-target complexes being configured to emit a photon of light when excited by current between the electrodes, a flow-path for the fluid containing the targets, wherein, each of the chambers have a chamber inlet for fluid communication between the sample flow-path and the probes within the chamber, the chamber inlet being configured as a diffusion barrier to prevent diffusion of the probe-target complexes between the chambers to an extent that causes erroneous detection results.
摘要翻译： 一种用于检测流体中的目标分子的微流体装置，所述微流体装置具有腔室阵列，每个腔室包含用于与靶分子反应以形成探针 - 目标复合物的电化学发光（ECL）探针，以及位于每个腔室中的电极， 接收电脉冲，所述探针 - 目标复合体被配置为当由电极之间的电流激发时发射光的光子，用于包含靶的流体的流动路径，其中每个腔室具有用于流体连通的腔室入口 在样品流动路径和腔室内的探针之间，腔室入口被配置为扩散阻挡层，以防止探针 - 目标复合物在腔室之间扩散到导致错误检测结果的程度。
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公开(公告)号：US20110312606A1
公开(公告)日：2011-12-22
申请号：US13150191
申请日：2011-06-01
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A lab-on-a-chip (LOC) device for analyzing a sample fluid, the LOC device having a supporting substrate, a sample inlet for receiving the sample, a microsystems technology (MST) layer with functional sections for processing and analyzing the sample, and, CMOS circuitry between the supporting substrate and the MST layer, the CMOS circuitry having digital memory for storing data and operational information to operatively control the functional sections during processing and analysis of the sample.
摘要翻译： 用于分析样品流体的实验室片（LOC）装置，具有支撑衬底的LOC装置，用于接收样品的样品入口，具有用于处理和分析样品的功能部分的微系统技术（MST）层 以及在支撑衬底和MST层之间的CMOS电路，CMOS电路具有用于存储数据的数字存储器和操作信息，以在样品的处理和分析期间可操作地控制功能部分。
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公开(公告)号：US07980669B2
公开(公告)日：2011-07-19
申请号：US12559346
申请日：2009-09-14
CPC分类号： B41J2/14056 , B41J2/14072 , B41J2/1601 , B41J2/1628 , B41J2/1629 , B41J2/1631 , B41J2002/14169 , B41J2002/14403
摘要： An inkjet printhead is disclosed. The printhead has an array of ink chambers. Each ink chamber has a nozzle and a thermal actuator for generating vapor bubbles to eject ink through the nozzle. The thermal actuator has a pair of contacts and at least two parallel current paths between the contacts. Each of the current paths has a plurality of heater elements for nucleating a vapor bubble.
摘要翻译： 公开了一种喷墨打印头。 打印头有一个墨水盒阵列。 每个墨水室具有喷嘴和用于产生蒸汽气泡以通过喷嘴喷射墨水的热致动器。 热致动器具有一对触点和在触头之间的至少两个平行的电流路径。 每个电流路径具有用于使蒸气泡成核的多个加热元件。
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5.发明申请INKJET PRINTHEAD WITH HEATER ELEMENTS HAVING PARALLEL CURRENT PATHS 有权具有并联电流的加热器元件的INKJET PRINTHEAD公开(公告)号：US20100134567A1
公开(公告)日：2010-06-03
申请号：US12702122
申请日：2010-02-08
IPC分类号： B41J2/05
CPC分类号： B41J2/1404 , B41J2/1601 , B41J2/1628 , B41J2/1631 , B41J2/1639 , B41J2/1642 , B41J2/1645 , B41J2002/14169 , B41J2002/14403 , B41J2002/14475
摘要： An inkjet printhead having an array of ink chambers is disclosed. Each ink chamber has a nozzle and a heater element for generating vapour bubbles to eject ink through the nozzle. The heater element has multiple current paths connected in parallel. Each current path has at least one portion with a reduced cross-section relative to the remainder of the current path. A cross bracing structure is also provided for connecting intermediate portions of the current paths.
摘要翻译： 公开了一种具有墨腔阵列的喷墨打印头。 每个墨室具有喷嘴和用于产生蒸汽气泡以通过喷嘴喷射墨水的加热器元件。 加热器元件具有并联连接的多个电流路径。 每个电流路径具有相对于当前路径的其余部分具有减小的横截面的至少一个部分。 还提供了用于连接电流路径的中间部分的交叉支撑结构。
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公开(公告)号：US07549735B2
公开(公告)日：2009-06-23
申请号：US11246699
申请日：2005-10-11
CPC分类号： B41J2/1404 , B41J2/14056 , B41J2/1412 , B41J2/1603 , B41J2/1628 , B41J2/1629 , B41J2/1631 , B41J2/1632 , B41J2/1642 , B41J2002/14169 , B41J2002/14403
摘要： An inkjet printhead comprising: an array of ink chambers, each having a nozzle and an actuator for ejecting ink through the nozzle; wherein during use, the actuator initiates a quadrupole pressure pulse that is symmetrical about two orthogonal axes parallel to the plane of the nozzle, the orthogonal axes intersecting a mutually orthogonal axis extending through the center of the nozzle.
摘要翻译： 一种喷墨打印头，包括：一组墨室，每个墨室具有喷嘴和用于通过喷嘴喷射墨的致动器; 其中在使用过程中，致动器启动一个四极压力脉冲，该四极压力脉冲是关于平行于喷嘴平面的两个正交轴线对称的，正交轴与延伸穿过喷嘴中心的相互正交的轴相交。
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公开(公告)号：US20110312789A1
公开(公告)日：2011-12-22
申请号：US13150193
申请日：2011-06-01
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A lab-on-a-chip (LOC) device for analyzing a sample fluid, the LOC device having a supporting substrate, a sample inlet for receiving the sample, a microsystems technology (MST) layer with functional sections for processing and analyzing the sample, and, CMOS circuitry between the supporting substrate and the MST layer, the CMOS circuitry having flash memory for storing program data to operate the functional sections during processing and analysis of the sample.
摘要翻译： 用于分析样品流体的实验室片（LOC）装置，具有支撑衬底的LOC装置，用于接收样品的样品入口，具有用于处理和分析样品的功能部分的微系统技术（MST）层 以及在支撑衬底和MST层之间的CMOS电路，CMOS电路具有用于在处理和分析样本期间存储程序数据以操作功能部分的闪存。
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公开(公告)号：US20110312773A1
公开(公告)日：2011-12-22
申请号：US13150150
申请日：2011-06-01
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A microfluidic device having an inlet for receiving a liquid flowing through the microfluidic device, an outlet downstream of the inlet, and, a fault-tolerant multiple valve assembly having a plurality of flow-paths extending from the inlet to the outlet and a plurality of valves positioned along each of the flow-paths respectively.
摘要翻译： 一种微流体装置，其具有用于接收流过微流体装置的液体的入口，入口下游的出口，以及具有从入口延伸到出口的多个流动路径的容错多阀组件，以及多个 分别沿着每个流动路径定位的阀。
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9.发明申请FAULT-TOLERANT MULTIPLE VALVE ASSEMBLY WITH THERMAL BEND-ACTUATOR PRESSURE PULSE VALVE 审中-公开具有热弯曲致动器压力脉冲阀的容错多个阀组件公开(公告)号：US20110311414A1
公开(公告)日：2011-12-22
申请号：US13150219
申请日：2011-06-01
IPC分类号： B01L99/00
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A fault-tolerant multiple valve assembly for a microfluidic device, the multiple valve assembly having an inlet for receiving a liquid flowing through the microfluidic device, an outlet downstream of the inlet, a plurality of flow-paths extending from the inlet to the outlet, and, a plurality of valves positioned along each of the flow-paths respectively, wherein, each of the valves has a movable member for contacting the liquid, and a thermal expansion actuator for displacing the movable member to generate a pulse in the liquid to dislodge the meniscus such that the liquid flow towards the outlet resumes.
摘要翻译： 一种用于微流体装置的容错多阀组件，所述多阀组件具有用于接收流过所述微流体装置的液体的入口，所述入口下游的出口，从所述入口延伸到所述出口的多个流动路径， 以及分别沿着每个流路定位的多个阀，其中，每个阀具有用于接触液体的可移动部件和用于移动可移动部件以在液体中产生脉冲以移除的热膨胀致动器 弯液面使液体流向出口恢复。
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公开(公告)号：US20110311407A1
公开(公告)日：2011-12-22
申请号：US13150205
申请日：2011-06-01
IPC分类号： B01L3/00
CPC分类号： C12Q1/68 , B01L3/5027 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L2200/10 , B01L2300/023 , B01L2300/024 , B01L2300/0636 , B01L2300/0654 , B01L2300/0883 , B01L2300/10 , B01L2300/1827 , B01L2400/0406 , B01L2400/0633 , B01L2400/0677 , B01L2400/0688 , F16K99/003 , F16K99/0036 , Y10T137/0352 , Y10T137/0391 , Y10T137/1044 , Y10T137/206 , Y10T137/2076 , Y10T137/2202 , Y10T436/107497 , Y10T436/11 , Y10T436/143333 , Y10T436/145555 , Y10T436/173845 , Y10T436/203332 , Y10T436/25 , Y10T436/25375
摘要： A microfluidic valve having an inlet for receiving a flow of liquid, an outlet for outputting the flow of liquid, a meniscus anchor between the inlet and the outlet such that the flow from the inlet towards the outlet stops at the meniscus anchor where the liquid forms a meniscus, and, a valve heater for heating the meniscus such that the meniscus unpins from the meniscus anchor such that the flow towards the outlet resumes.
摘要翻译： 一种微流体阀，其具有用于接收液体流的入口，用于输出液体流的出口，在入口和出口之间的弯液面锚，使得从入口到出口的流动停止在液体形成的弯液面锚 弯月面，以及用于加热弯月面的阀加热器，使得弯液面从弯月面锚固件脱开，使得朝向出口的流动恢复。
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