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1.发明申请Pin for Anchorage of Articular Prosthesis, Articular Prosthesis Comprising Said Pin, Tibial Component and Articular Prosthesis for the Knee Comprising Said Tibial Component 审中-公开关节假体的固定针，包括所述胫骨部件的膝部的所述针，胫骨部件和关节假体的关节假体公开(公告)号：US20080200957A1
公开(公告)日：2008-08-21
申请号：US12065039
申请日：2006-09-04
IPC分类号： A61B17/56
CPC分类号： A61F2/30721 , A61F2/30749 , A61F2/3859 , A61F2/389 , A61F2/40 , A61F2/4202 , A61F2002/30014 , A61F2002/30113 , A61F2002/30115 , A61F2002/30125 , A61F2002/30133 , A61F2002/30138 , A61F2002/30153 , A61F2002/30156 , A61F2002/30235 , A61F2002/30332 , A61F2002/30405 , A61F2002/30451 , A61F2002/30487 , A61F2002/305 , A61F2002/30571 , A61F2002/30579 , A61F2002/30593 , A61F2002/30604 , A61F2002/30772 , A61F2002/30785 , A61F2002/30787 , A61F2002/30797 , A61F2002/30805 , A61F2002/30822 , A61F2002/30841 , A61F2002/30878 , A61F2002/30881 , A61F2002/30891 , A61F2002/30892 , A61F2002/30894 , A61F2002/30957 , A61F2002/3895 , A61F2220/0025 , A61F2220/0033 , A61F2220/0058 , A61F2230/0006 , A61F2230/0008 , A61F2230/0015 , A61F2230/0017 , A61F2230/0019 , A61F2230/0023 , A61F2230/0069 , A61F2250/0018 , A61F2310/00023 , A61F2310/00179 , A61F2310/00293
摘要： A pin for the anchoring of articular prostheses includes a connecting portion (4) with a prosthesis (2) and an engagement portion (5) in a hole obtained within a bone. The engagement portion (5) is at least partly deformable in a radial direction and in a resilient way, in order to allow the instantaneous blocking of the pin (1) in the hole and the primary fixing of the prosthesis (2) on the bone, so as to al low an easy primary fixing of the prosthesis by simply introducing with a pressure the connecting portion in the hole obtained within the bone itself.
摘要翻译： 用于锚固关节假体的销包括在骨头内获得的孔中具有假体（2）和接合部分（5）的连接部分（4）。 接合部分（5）可在径向方向和弹性方向上至少部分地变形，以便允许销（1）在孔中的瞬时阻塞以及假体（2）在骨头上的主要固定 ，以便通过简单地在骨骼内部获得的孔中的连接部分的压力简单地引入假体来简化主要固定。
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2.发明授权Cartilaginous and osteochondral substitute comprising multilayer structure and use thereof 有权软骨和骨软骨替代物，包括多层结构及其用途公开(公告)号：US09155818B2
公开(公告)日：2015-10-13
申请号：US11817172
申请日：2006-03-02
IPC分类号： A61L27/42 , A61L27/32 , A61L27/34 , A61L27/26 , A61L27/46 , A61L27/54 , A61L27/56 , A61L27/24 , A61L27/48 , A61L24/10
CPC分类号： A61L27/425 , A61L24/102 , A61L27/24 , A61L27/26 , A61L27/32 , A61L27/34 , A61L27/46 , A61L27/48 , A61L27/54 , A61L27/56 , C08L89/06
摘要： The present invention relates to a multilayer structure (1) including a first upper layer (2) consisting of an organic matrix including collagen and at least a lower layer (3, 4, . . . 10) consisting of a composite matrix including hydroxylapatite and collagen. Furthermore, the present invention relates to a cartilaginous substitute including said multilayer structure (1) as well as an osteochondral substitute including said multilayer structure (1). Finally, the present invention relates to the use of said multilayer structure (1) for the preparation of said cartilaginous substitute and said osteochondral substitute for the treatment of cartilaginous defects and osteochondral defects or for the neo-formation of a cartilaginous tissue and/or a subchondral bone tissue.
摘要翻译： 本发明涉及一种多层结构（1），该多层结构（1）包括由包括胶原的有机基质和至少一层下层（3,4，...）构成的第一上层（2），所述下层由包括羟基磷灰石和 胶原。 此外，本发明涉及包括所述多层结构（1）的软骨替代物以及包括所述多层结构（1）的骨软骨替代物。 最后，本发明涉及所述多层结构（1）用于制备所述软骨替代物和所述骨软骨替代物用于治疗软骨缺损和骨软骨缺损或用于软骨组织和/或 软骨下骨组织。
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3.发明申请公开(公告)号：US20090232875A1
公开(公告)日：2009-09-17
申请号：US11817172
申请日：2006-03-02
CPC分类号： A61L27/425 , A61L24/102 , A61L27/24 , A61L27/26 , A61L27/32 , A61L27/34 , A61L27/46 , A61L27/48 , A61L27/54 , A61L27/56 , C08L89/06
摘要： The present invention relates to a multilayer structure (1) including a first upper layer (2) consisting of an organic matrix including collagen and at least a lower layer (3, 4, . . . 10) consisting of a composite matrix including hydroxylapatite and collagen. Furthermore, the present invention relates to a cartilaginous substitute including said multilayer structure (1) as well as an osteochondral substitute including said multilayer structure (1). Finally, the present invention relates to the use of said multilayer structure (1) for the preparation of said cartilaginous substitute and said osteochondral substitute for the treatment of cartilaginous defects and osteochondral defects or for the neo-formation of a cartilaginous tissue and/or a subchondral bone tissue.
摘要翻译： 本发明涉及一种多层结构（1），该多层结构（1）包括由包括胶原的有机基质和至少一层下层（3,4，...）构成的第一上层（2），所述下层由包括羟基磷灰石和 胶原。 此外，本发明涉及包括所述多层结构（1）的软骨替代物以及包括所述多层结构（1）的骨软骨替代物。 最后，本发明涉及所述多层结构（1）用于制备所述软骨替代物和所述骨软骨替代物用于治疗软骨缺损和骨软骨缺陷或用于软骨组织和/或 软骨下骨组织。
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4.发明授权Plurisubstituted hydroxyapatite and the composite thereof with a natural and/or synthetic polymer, their preparation and uses thereof 有权多取代羟基磷灰石及其与天然和/或合成聚合物的复合物及其制备及用途公开(公告)号：US09327976B2
公开(公告)日：2016-05-03
申请号：US12089887
申请日：2006-10-12
申请人： Elena Landi , Anna Tampieri , Giancarlo Celotti , Simone Sprio , Daniele Pressato , Claudio De Luca
发明人： Elena Landi , Anna Tampieri , Giancarlo Celotti , Simone Sprio , Daniele Pressato , Claudio De Luca
CPC分类号： C01B25/322 , A61F2/28 , A61F2310/00293 , A61L27/12 , A61L27/46 , C01B25/16
摘要： The present invention relates to a hydroxyapatite multi-substituted with, physiologically compatible ion species and to its biohybrid composite with a natural and/or synthetic polymer, which are useful in the preparation of a biomimetic bone substitute for treating bone tissue defects. Furthermore, the present invention relates to a method for their preparation and uses.
摘要翻译： 本发明涉及多生物相容性离子物质的多羟基磷灰石，及其与天然和/或合成聚合物的生物杂交复合物，其可用于制备用于治疗骨组织缺陷的仿生骨替代物。 此外，本发明涉及其制备方法和用途。
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5.发明申请Plurisubstituted Hydroxyapatite and the Composite Thereof With a Natural and/or Synthetic Polymer, Their Preparation and Uses Thereof 有权天然和/或合成聚合物的多取代羟基磷灰石及其复合物及其制备及其用途公开(公告)号：US20080262121A1
公开(公告)日：2008-10-23
申请号：US12089887
申请日：2006-10-12
申请人： Elena Landi , Anna Tampieri , Giancarlo Celotti , Simone Sprio , Daniele Pressato , Claudio De Luca
发明人： Elena Landi , Anna Tampieri , Giancarlo Celotti , Simone Sprio , Daniele Pressato , Claudio De Luca
CPC分类号： C01B25/322 , A61F2/28 , A61F2310/00293 , A61L27/12 , A61L27/46 , C01B25/16
摘要： The present invention relates to a hydroxyapatite multi-substituted with, physiologically compatible ion species and to its biohybrid composite with a natural and/or synthetic polymer, which are useful in the preparation of a biomimetic bone substitute for treating bone tissue defects. Furthermore, the present invention relates to a method for their preparation and uses .
摘要翻译： 本发明涉及多生物相容性离子物质的多羟基磷灰石，及其与天然和/或合成聚合物的生物杂交复合物，其可用于制备用于治疗骨组织缺陷的仿生骨替代物。 此外，本发明涉及其制备方法和用途。
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