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公开(公告)号:US5975369A
公开(公告)日:1999-11-02
申请号:US869501
申请日:1997-06-05
申请人: Michael A. Yurkewicz , Robert J. Smith , Gregg S. Montgomery , Stephen Getsy , David E. Babcock , Mike G. Palma , Lee Albrecht , Paul W. Robbins
发明人: Michael A. Yurkewicz , Robert J. Smith , Gregg S. Montgomery , Stephen Getsy , David E. Babcock , Mike G. Palma , Lee Albrecht , Paul W. Robbins
CPC分类号: B65D51/18 , B65D41/32 , B65D47/243 , B65D2101/0023 , B65D2101/0038 , B65D2251/0015 , B65D2251/0087
摘要: A container closure includes a shell attachable to a container around a container opening thereof. The shell has a shell opening in fluid communication with the container opening when the shell is attached to the container. A tip is received on the shell movable between a closed position sealing the shell opening and an open position. A cover is releasably attached to the shell in a manner indicative of the tip being positioned in the closed position when the cover is attached to the shell. Both the shell and the cover may be provided with tamper-evident bands. The present invention is particularly well adapted to be formed as a push-pull container closure for sports bottles and the like.
摘要翻译: 容器封闭件包括可围绕其容器开口附近的容器的壳体。 当壳体附接到容器时,壳体具有与容器开口流体连通的壳体开口。 在壳体上容纳一个尖端,该壳体可在封闭壳体开口和打开位置的关闭位置之间移动。 当盖子附接到壳体时,盖子以指示尖端位于关闭位置的方式可拆卸地附接到壳体。 外壳和盖都可以设有防窃启带。 本发明特别适合于形成用于运动瓶等的推拉式容器盖。
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公开(公告)号:US06321924B1
公开(公告)日:2001-11-27
申请号:US09415444
申请日:1999-10-08
申请人: Michael A. Yurkewicz , Robert J. Smith , Gregg S. Montgomery , Stephen Getsy , David E. Babcock , Mike G. Palma , Lee Albrecht , Paul W. Robbins
发明人: Michael A. Yurkewicz , Robert J. Smith , Gregg S. Montgomery , Stephen Getsy , David E. Babcock , Mike G. Palma , Lee Albrecht , Paul W. Robbins
IPC分类号: B67D533
CPC分类号: B65D51/18 , B65D41/32 , B65D47/243 , B65D2101/0023 , B65D2101/0038 , B65D2251/0015 , B65D2251/0087
摘要: A container closure is disclosed which includes a shell attachable to a container around a container opening thereof. The shell has a shell opening in fluid communication with the container opening when the shell is attached to the container. A tip is received on the shell movable between a closed position sealing the shell opening and an open position. A cover is releasably attached to the shell in a manner indicative of the tip being positioned in the closed position when the cover is attached to the shell. Both the shell and the cover may be provided with tamper-evident bands. The present invention is particularly well adapted to be formed as a push-pull container closure for sports bottles and the like.
摘要翻译: 公开了一种容器封闭件,其包括可围绕其容器开口附接到容器的壳体。 当壳体附接到容器时,壳体具有与容器开口流体连通的壳体开口。 在壳体上容纳一个尖端,该壳体可在封闭壳体开口和打开位置的关闭位置之间移动。 当盖子附接到壳体时,盖子以指示尖端位于关闭位置的方式可拆卸地附接到壳体。 外壳和盖都可以设有防窃启带。 本发明特别适合于形成用于运动瓶等的推拉式容器盖。
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公开(公告)号:US06758359B2
公开(公告)日:2004-07-06
申请号:US09975081
申请日:2001-10-11
申请人: Michael Yurkewicz , Robert J. Smith , Gregg S. Montgomery , Stephen Getsy , David E. Babcock , Mike G. Palma , Lee Albrecht , Paul W. Robbins
发明人: Michael Yurkewicz , Robert J. Smith , Gregg S. Montgomery , Stephen Getsy , David E. Babcock , Mike G. Palma , Lee Albrecht , Paul W. Robbins
IPC分类号: B67D533
CPC分类号: B65D51/18 , B65D41/32 , B65D47/243 , B65D2101/0023 , B65D2101/0038 , B65D2251/0015 , B65D2251/0087
摘要: A container closure is disclosed which includes a shell attachable to a container around a container opening thereof. The shell has a shell opening in fluid communication with the container opening when the shell is attached to the container. A tip is received on the shell movable between a closed position sealing the shell opening and an open position. A cover is releasably attached to the shell in a manner indicative of the tip being positioned in the closed position when the cover is attached to the shell. Both the shell and the cover may be provided with tamper-evident bands. The present invention is particularly well adapted to be formed as a push-pull container closure for sports bottles and the like.
摘要翻译: 公开了一种容器封闭件,其包括可围绕其容器开口附接到容器的壳体。 当壳体附接到容器时,壳体具有与容器开口流体连通的壳体开口。 在壳体上容纳一个尖端,该壳体可在封闭壳体开口和打开位置的关闭位置之间移动。 当盖子附接到壳体时,盖子以指示尖端位于关闭位置的方式可拆卸地附接到壳体。 外壳和盖都可以设有防窃启带。 本发明特别适合于形成用于运动瓶等的推拉式容器盖。
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公开(公告)号:US20130197433A1
公开(公告)日:2013-08-01
申请号:US13745397
申请日:2013-01-18
申请人: David E. Babcock
发明人: David E. Babcock
IPC分类号: A61L29/08
CPC分类号: A61L29/085 , A61L27/34 , A61L29/14 , A61L31/10 , A61L2400/10 , A61L2420/06 , A61L2420/08 , C08L39/06
摘要: Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein.
摘要翻译: 本发明的实施例包括光滑的医疗装置涂层。 在一个实施方案中,本发明包括用于医疗装置的涂层,其包括由光反应性基团衍生的聚乙烯吡咯烷酮的第一层; 和包含至少两个光反应性基团的第一交联剂; 设置在第一层上的第二层包含用光反应性基团衍生的聚乙烯吡咯烷酮; 包含至少两个光反应性基团的第二交联剂; 和包含聚丙烯酰胺的聚合物,所述聚合物用至少一种光反应性基团衍生化。 本文还包括其它实施例。
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公开(公告)号:US20110229457A1
公开(公告)日:2011-09-22
申请号:US13046547
申请日:2011-03-11
IPC分类号: A61K39/395 , A61K47/36 , A61K38/02 , A61K38/43 , A61K31/713 , A61P25/28 , A61P25/16 , A61P25/00 , A61P27/02 , A61P27/06 , A61P31/20 , A61P31/14 , A61P19/02 , A61K31/7088 , A61K31/7052
CPC分类号: A61K9/0024 , A61K9/0051 , A61K47/10 , A61K47/14 , A61K47/36 , A61K47/40 , C07K16/00 , C07K2317/55
摘要: The invention provides a formulation that includes a biocompatible solvent system, a biodegradable polymer that is substantially soluble in the biocompatible solvent system, and an active pharmaceutical ingredient that is substantially insoluble in the biocompatible solvent system. The formulation can form a drug-eluting implant, when injected into mammalian tissue. The solvent system and the biodegradable polymer can be selected so that the implant provides extended, delayed, controlled and/or modified release of the active pharmaceutical ingredient, for example, over the course of days, weeks or months.
摘要翻译: 本发明提供了一种制剂,其包括生物相容性溶剂体系,基本上可溶于生物相容性溶剂体系的可生物降解聚合物,以及基本上不溶于生物相容性溶剂体系的活性药物成分。 当注射到哺乳动物组织中时,制剂可以形成药物洗脱植入物。 可以选择溶剂体系和可生物降解的聚合物,使得植入物提供活性药物成分的延长,延迟,受控和/或修饰释放,例如在数天,数周或数月的过程中。
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公开(公告)号:US20080243243A1
公开(公告)日:2008-10-02
申请号:US11824908
申请日:2007-07-03
IPC分类号: A61F2/06
CPC分类号: A61L29/085 , A61F2/91 , A61L27/34 , A61L31/10 , A61L33/0029 , A61L33/122 , A61L33/128 , A61L2420/08 , C08L89/00 , C08L89/06
摘要: Coatings including adhesion factors for the surfaces of implantable medical articles are disclosed. The coatings are used to improve the function of the device by promoting a pro-healing response following implantation. The coatings can modulate endothelialization of the article surface to reduce the risk of adverse tissue responses that may reduce the functionality of the device.
摘要翻译: 公开了包括可植入医疗制品表面的粘附因子的涂层。 涂层用于通过促进植入后的预愈合反应来改善装置的功能。 涂层可以调节制品表面的内皮化,以减少可能降低装置功能的不利组织反应的风险。
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公开(公告)号:US06769559B2
公开(公告)日:2004-08-03
申请号:US10303278
申请日:2002-11-25
申请人: John D. Ziegler , David E. Babcock , Coy Herald
发明人: John D. Ziegler , David E. Babcock , Coy Herald
IPC分类号: B65D5300
CPC分类号: B65D41/3409 , B65D41/045
摘要: A venting plastic closure for use with an associated container includes an outer plastic cap having a top wall portion and an annular depending skirt including an internal thread formation. A disc-shaped sealing liner is positioned on the inside surface of the top wall portion for creating a top/inside seal with the associated container. In order to facilitate venting of gas pressure from within the container, and to facilitate removal of the closure from the container by consumers, the closure includes one or more positive stop elements which engage the container after the sealing liner of the closure has been sealingly engaged therewith. The stop elements act to limit the degree of sealing engagement between the sealing lines of the closure and the finish of the closure.
摘要翻译: 用于与相关容器一起使用的排气塑料盖包括外塑料盖,其具有顶壁部分和包括内螺纹结构的环形悬垂裙部。 盘形密封衬套位于顶壁部分的内表面上,用于与相关联的容器形成顶部/内部密封。 为了便于从容器内排出气体压力,并且为了便于消费者从容器中取出封闭件,封闭件包括一个或多个止动件,其在封闭件的密封衬垫已密封接合之后与容器接合 随之而来。 止动元件用于限制封闭件的密封线和封闭件的封边之间的密封接合程度。
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公开(公告)号:US06557714B2
公开(公告)日:2003-05-06
申请号:US09815120
申请日:2001-03-22
申请人: David E. Babcock , Lawrence Smeyak , Coy Hearld
发明人: David E. Babcock , Lawrence Smeyak , Coy Hearld
IPC分类号: B65D4134
CPC分类号: B65D1/023 , B29B2911/1444 , B65D41/3409
摘要: A tamper-evident package includes a plastic closure having a top wall portion, a depending annular skirt portion, and a tamper band at least partially detachably connected to the skirt portion. The package further includes a container having a neck portion configured for tamper-indicating cooperation with the projections on the tamper band. The container includes a plurality of circumferentially spaced ratchet-like locking teeth, each of which presents a locking surface for interfering engagement with a respective one of the projections of the closure tamper band. The arrangement is particularly configured to promote rapid tamper-indication attendant to relatively little rotation of the closure relative to the container.
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公开(公告)号:US06341721B1
公开(公告)日:2002-01-29
申请号:US09815025
申请日:2001-03-22
申请人: Coy M. Herald , David E. Babcock
发明人: Coy M. Herald , David E. Babcock
IPC分类号: B65D4700
CPC分类号: B65D47/243
摘要: A self-sealing, dispensing closure comprises a shell, a cover moveable axially toward and away from the shell, and a valve connected to the cover via a stem, and adapted to close the outlet when the cover is moved away from the shell and to open the outlet when the cover is moved toward the shell. The shell has a generally conical surface. The cover has a resilient skirt, which is discontinuous. The skirt engages the surface to bias the cover away from the shell and to bias the valve toward the closing position but to permit the cover to move toward the shell and to permit the valve to move away from the closing position. The shell and the cover have formations coactive to prevent the cover from being moved toward the shell and the valve from being moved away from the closing position at certain but not all positions of relative rotation of the shell and the cover.
摘要翻译: 自密封分配封闭件包括壳体,可轴向移动并远离壳体的盖子,以及通过杆连接到盖子的阀门,并且适于当盖子从壳体移开时关闭出口,并且 当盖子向外壳移动时打开插座。 壳体具有大致圆锥形的表面。 该盖具有弹性裙部,其不连续。 裙部接合表面以将盖偏离壳体并且将阀门朝向关闭位置偏置,但是允许盖子朝壳体移动并允许阀门从关闭位置移开。 壳体和盖具有共同作用以防止盖向外壳移动并且阀不会在外壳和盖的相对旋转的某些但不是全部位置处远离关闭位置移动。
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公开(公告)号:US5819976A
公开(公告)日:1998-10-13
申请号:US746710
申请日:1996-11-15
申请人: Ted W. Boehm , David L. Cerny , Wendell D. Willingham , Daniel J. Denman , Sheldon L. Wilde , Stephen W. McBride , Hugh C. Urmston , Ralph H. Whitney , David E. Babcock , Joseph M. Ladina
发明人: Ted W. Boehm , David L. Cerny , Wendell D. Willingham , Daniel J. Denman , Sheldon L. Wilde , Stephen W. McBride , Hugh C. Urmston , Ralph H. Whitney , David E. Babcock , Joseph M. Ladina
CPC分类号: B65D51/28 , Y10S215/902
摘要: A promotional closure includes a sealed promotion-receiving member in the form of a compartment positioned generally within an outer closure cap, for disposition within an associated container. The sealed configuration of the promotion compartment desirably acts to isolate the promotional element therein from the contents of the container. Use on a container having carbonated contents is particularly facilitated by an arrangement by which a plastic film cover member which seals the compartment is sealed to an annular flange of the compartment to permit predetermined delamination and release of gas pressure from within the interior of the compartment.
摘要翻译: 促销关闭包括密封的促销接收构件,其为通常位于外部封闭帽内部的隔室的形式,用于配置在相关联的容器内。 促销隔间的密封结构理想地用于将其中的促销元件与容器的内容物隔离。 在具有碳酸化内容物的容器上的使用特别有利于通过这种装置将密封隔室的塑料膜盖构件密封到隔室的环形凸缘,以允许气室压力从室内部预先分层和释放。
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