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1.发明授权公开(公告)号：US06716196B2
公开(公告)日：2004-04-06
申请号：US09797483
申请日：2001-02-28
IPC分类号： A61M5178
CPC分类号： A61M25/0136 , A61B17/22 , A61B2017/00243 , A61B2017/22082 , A61B2017/3488 , A61B2018/00273 , A61B2018/00815 , A61B2018/1425 , A61B2018/1435 , A61B2090/3784 , A61M25/0084 , A61M25/0133 , A61M25/0147 , A61N7/02
摘要： This is a method and an apparatus for the introduction of therapeutic compounds into tissue, particularly cardiac tissue. The apparatus includes a catheter having an elongated flexible body and a tissue infusion apparatus including a hollow infusion needle configured to secure the needle into the tissue when the needle is at least partially inserted into the tissue to help prevent inadvertent removal of the needle from the tissue. This permits the selected therapeutic compound to be delivered to a specific site. The catheter may also include a visualization assembly including a transducer at the distal end of the body.
摘要翻译： 这是用于将治疗化合物引入组织，特别是心脏组织的方法和装置。 所述装置包括具有细长柔性体的导管和包括中空输液针的组织浸液装置，所述中空灌注针构造成当针至少部分插入组织中时将针固定到组织中，以帮助防止针头从组织中无意中移除 。 这允许将所选择的治疗化合物递送到特定部位。 导管还可以包括可视化组件，其包括在身体的远端处的换能器。
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公开(公告)号：US5871443A
公开(公告)日：1999-02-16
申请号：US747811
申请日：1996-11-14
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/04
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
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公开(公告)号：US6052607A
公开(公告)日：2000-04-18
申请号：US34553
申请日：1998-03-03
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/0408
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
摘要翻译： 用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。 每个花键的主体由多个交替导电层和非导电层形成。 提供单独的导电路径以将每个电极连接到不同的一个导电层。 每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。
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公开(公告)号：US5509419A
公开(公告)日：1996-04-23
申请号：US168476
申请日：1993-12-16
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61N5/02
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can he processed.
摘要翻译： 用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。 每个花键的主体由多个交替导电层和非导电层形成。 提供单独的导电路径以将每个电极连接到不同的一个导电层。 每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。
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公开(公告)号：US5471982A
公开(公告)日：1995-12-05
申请号：US951728
申请日：1992-09-29
IPC分类号： A61B5/042 , A61B18/14 , A61N1/06 , A61B5/0402
CPC分类号： A61B5/6856 , A61B18/1492 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61N1/06 , A61B2017/22038 , A61B2018/00083 , A61B2018/00148 , A61B2018/0016 , A61B2018/00214 , A61B2018/0022 , A61B2018/00357 , A61B2018/00839 , A61B2018/1861 , A61B2562/0209 , A61B2562/043
摘要： An improved probe for cardiac diagnosis and/or treatment includes a control handle and a catheter for insertion into the heart. The catheter has a distal end, a proximal end and at least one lumen connecting said distal and proximal ends. It also includes a flexible inner tube and an outer sheath enveloping said tube. At least one measuring electrode or ablation device is attached to the distal end of the tube. The outer sheath and the inner tube are rotatable relative to each other so that the electrode or device can be rotated within the heart without rotating the outer sheath. The sheath is also axially movable relative to the tube to selectively enclose or expose the electrode or device for use.
摘要翻译： 用于心脏诊断和/或治疗的改进探针包括控制手柄和用于插入心脏的导管。 导管具有远端，近端和连接所述远端和近端的至少一个腔。 它还包括柔性内管和包封所述管的外护套。 至少一个测量电极或消融装置附接到管的远端。 外鞘和内管可相对于彼此旋转，使得电极或装置可以在心脏内旋转而不旋转外护套。 鞘也可以相对于管轴向移动，以选择性地包围或暴露电极或装置以供使用。
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公开(公告)号：US6163716A
公开(公告)日：2000-12-19
申请号：US433604
申请日：1999-11-02
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05 , A61B5/0402
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , Y10T29/49002 , Y10T29/49117 , C08L1/02
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connnected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
摘要翻译： 用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。 每个花键的主体由多个交替导电层和非导电层形成。 提供单独的导电路径以将每个电极连接到不同的一个导电层。 每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。
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公开(公告)号：US5549108A
公开(公告)日：1996-08-27
申请号：US252060
申请日：1994-06-01
IPC分类号： A61B5/042 , A61N1/06 , A61B5/0402 , A61N1/05
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61N1/06 , A61B2562/0209 , A61B2562/043
摘要： A cardiac diagnosis and treatment system comprises a support carrying at least two electrodes. A conductor is associated with the support for selectively directing electrical signals to and from each electrode. The conductor includes a first buss for delivering power from an external power source, a second buss for transmitting electrode signals to an external signal processor, and a third buss for receiving control signals from an external signal source to multiplex the electrode signals from the electrodes through the second buss. A conduction line conducts power, control signals, and electrode signals from the external sources to the conductor.
摘要翻译： 心脏诊断和治疗系统包括承载至少两个电极的支撑件。 导体与用于选择性地将电信号导向每个电极和从每个电极引导的支撑件相关联。 导体包括用于从外部电源传递电力的第一总线，用于将电极信号传输到外部信号处理器的第二总线，以及用于从外部信号源接收控制信号的第三总线，以将来自电极的电极信号多路复用 第二个总线 导线将电源，控制信号和电极信号从外部源传导到导体。
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公开(公告)号：US5309910A
公开(公告)日：1994-05-10
申请号：US951157
申请日：1992-09-25
IPC分类号： A61B5/042 , A61B18/14 , A61B18/18 , A61L29/08 , A61L29/14 , A61L31/10 , A61L31/14 , A61N1/05
CPC分类号： A61B5/6856 , A61B5/0422 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61L29/085 , A61L29/145 , A61L31/10 , A61L31/145 , A61N1/056 , A61B18/14 , A61B18/18 , A61B2562/0209 , A61B2562/043 , Y10T29/49002 , Y10T29/49117
摘要： An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can be processed.
摘要翻译： 用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。 每个花键的主体由多个交替导电层和非导电层形成。 提供单独的导电路径以将每个电极连接到不同的一个导电层。 每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。
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公开(公告)号：US5313943A
公开(公告)日：1994-05-24
申请号：US951739
申请日：1992-09-25
CPC分类号： A61B5/6852 , A61B18/1492 , A61B5/0422 , A61B5/6853 , A61B5/6858 , A61B5/6859 , A61N1/056 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839 , A61B2018/0091 , A61B2018/1861 , A61B2218/002 , A61B2562/0209 , A61B2562/043
摘要： A system and method for cardiac diagnosis and treatment inserts the distal end of a catheter into a heart chamber. The distal end of the catheter supports at least one electrode. The catheter has a fluid flow conduit extending through it. The conduit has a valve that prevents fluid flow from the heart chamber into the conduit in response to in vivo pressure generated during heart systole and diastole. The valve permits fluid flow from the conduit into the heart at a pressure above the in vivo pressure. In use, the catheter locates the electrode in contact with a portion of the endocardium, and fluid is conducted from an external source through the conduit at a pressure above the in vivo pressure to flush the area surrounding the electrode.
摘要翻译： 用于心脏诊断和治疗的系统和方法将导管的远端插入心室。 导管的远端支撑至少一个电极。 导管具有延伸穿过其的流体流动管道。 导管具有一个阀，其能够响应心脏收缩期和舒张期期间产生的体内压力，防止流体从心室流入导管。 阀允许流体在高于体内压力的压力下从导管流入心脏。 在使用中，导管将电极定位成与心内膜的一部分接触，并且流体在高于体内压力的压力下从外部源通过导管传导以冲洗电极周围的区域。
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公开(公告)号：US08364236B2
公开(公告)日：2013-01-29
申请号：US13409352
申请日：2012-03-01
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/042 , A61B5/6858 , A61B5/6859 , A61B18/1492 , A61B2018/0016 , A61B2018/00267 , A61B2018/00351 , A61B2562/17 , F04C2270/0421 , Y10T29/49117
摘要： A device for insertion into a body lumen, includes: an electrode assembly strip with exposed electrodes including: a polymeric substrate having an upper surface and an opposed lower surface; one or more electrodes disposed over a portion of the upper surface of the polymeric substrate; one or more electrical traces disposed over a portion of the lower surface of the polymeric substrate in electrical communication with the one or more electrodes by way of metal plated holes through the substrate; and a flexible polymeric substrate having a substrate surface and a substrate wall; wherein the electrode assembly strip is compressingly and thermally bonded to the substrate surface of the flexible polymeric substrate to define a flexible electrode assembly strip; and wherein the electrode assembly strip has a thickness from about 0.0005 inches to about 0.008 inches.
摘要翻译： 一种用于插入体腔的装置，包括：具有暴露电极的电极组件带，包括：具有上表面和相对的下表面的聚合物基底; 设置在聚合物基材的上表面的一部分上的一个或多个电极; 一个或多个电迹线设置在所述聚合物基底的下表面的一部分上，通过穿过所述基底的金属电镀孔与所述一个或多个电极电连通; 以及具有衬底表面和衬底壁的柔性聚合物衬底; 其中所述电极组合条被压缩并热粘合到所述柔性聚合物基底的所述基底表面以限定柔性电极组合带; 并且其中所述电极组件条的厚度为约0.0005英寸至约0.008英寸。
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