公开(公告)号：US08452356B2

公开(公告)日：2013-05-28

申请号：US12434640

申请日：2009-05-02

申请人： Michael J. Vestel ,  Karen M. Nashold ,  Joseph R. Stetter ,  Diane P. Walter ,  Gregory W. Faris ,  Christopher Holland ,  Roger Schmidt

发明人： Michael J. Vestel ,  Karen M. Nashold ,  Joseph R. Stetter ,  Diane P. Walter ,  Gregory W. Faris ,  Christopher Holland ,  Roger Schmidt

IPC分类号： A61B5/00

CPC分类号： A61B5/1459 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/6833 ,  A61B5/6849 ,  A61B2562/028

摘要： Optical microneedles are adapted for near-infrared or mid-infrared in vivo spectroscopic sensing; and provide a MEMS-based spectrometer for continuous lactate and glucose monitoring by means of a near-infrared or mid-infrared optical microneedle array in a transdermal patch.

摘要翻译： 光学微针适用于近红外或中红外体内光谱传感; 并且通过在透皮贴剂中的近红外或中红外光学微针阵列提供用于连续乳酸盐和葡萄糖监测的基于MEMS的光谱仪。

公开(公告)号：US08536564B1

公开(公告)日：2013-09-17

申请号：US13246985

申请日：2011-09-28

申请人： Paul J. Resnick ,  Kristin L. Hertz ,  Christopher Holland ,  David Chichester ,  Paul Schwoebel

发明人： Paul J. Resnick ,  Kristin L. Hertz ,  Christopher Holland ,  David Chichester ,  Paul Schwoebel

IPC分类号： H01L29/06

CPC分类号： H01J9/02 ,  H01J3/04 ,  H01L21/31111

摘要： An integrated field emission array for ion desorption includes an electrically conductive substrate; a dielectric layer lying over the electrically conductive substrate comprising a plurality of laterally separated cavities extending through the dielectric layer; a like plurality of conically-shaped emitter tips on posts, each emitter tip/post disposed concentrically within a laterally separated cavity and electrically contacting the substrate; and a gate electrode structure lying over the dielectric layer, including a like plurality of circular gate apertures, each gate aperture disposed concentrically above an emitter tip/post to provide a like plurality of annular gate electrodes and wherein the lower edge of each annular gate electrode proximate the like emitter tip/post is rounded. Also disclosed herein are methods for fabricating an integrated field emission array.

摘要翻译： 用于离子解吸的集成场致发射阵列包括导电基片; 位于所述导电衬底上方的介电层包括延伸穿过所述电介质层的多个横向隔开的空腔; 在柱上具有相似的多个锥形发射器尖端，每个发射极尖端/柱同心地设置在横向分离的空腔内并与衬底电接触; 以及位于电介质层上方的栅极电极结构，包括相似的多个圆形栅极孔，每个栅极孔同心地设置在发射极尖端/柱上方，以提供相似的多个环形栅电极，并且其中每个环形栅电极的下边缘 靠近相似的发射器尖端/柱是圆形的。 本文还公开了用于制造集成场致发射阵列的方法。

公开(公告)号：US20060108180A1

公开(公告)日：2006-05-25

申请号：US11245967

申请日：2005-10-07

申请人： Ayzik Grach ,  Viktor Alekseyev ,  Christopher Holland ,  Paul Conley

发明人： Ayzik Grach ,  Viktor Alekseyev ,  Christopher Holland ,  Paul Conley

IPC分类号： F16N21/00

CPC分类号： F16N3/12

摘要： A device for dispensing a viscous fluid, such as grease gun for dispensing lubricant. The grease gun delivers lubricant with a selectable variation in pressure and/or output. It includes a reservoir, a pump having a reciprocating plunger, an electric motor driving the pump, and a variable speed transmission for transmitting power from the motor to the pump. The transmission has at least two different output speed settings adapted to be selected for reciprocating the plunger at different cyclical frequencies. A cycle indicator provides an indication corresponding to a quantity of lubricant dispensed. Embodiments of the grease gun include a pressure relief valve which inhibits damage due to an over-pressure condition, and a circuit breaker which inhibits damage due to electrical overload.

摘要翻译： 用于分配粘性流体的装置，例如用于分配润滑剂的油枪。 润滑脂枪可提供可选择的压力和/或输出变化的润滑剂。 其包括储存器，具有往复式柱塞的泵，驱动泵的电动机以及用于将动力从电动机传递到泵的变速传动装置。 变速器具有至少两个不同的输出速度设置，适于选择以不同的循环频率使柱塞往复运动。 循环指示器提供对应于分配的润滑剂的量的指示。 润滑脂枪的实施例包括抑制由于过压状态引起的损坏的减压阀，以及抑制由于电气过载造成的损坏的断路器。

公开(公告)号：US20050115641A1

公开(公告)日：2005-06-02

申请号：US10829663

申请日：2004-04-22

申请人： Barbara Fox ,  John McCurdy ,  Christopher Holland ,  Debbie Ianniello ,  Mark Weaver ,  Shannon Casey ,  Deanna Brown ,  Kennon Scott ,  James Harney ,  Dana Ayres ,  Robert Beach ,  Timothy Reed ,  Charles Mauro ,  Lester Miller ,  Fred Williams

发明人： Barbara Fox ,  John McCurdy ,  Christopher Holland ,  Debbie Ianniello ,  Mark Weaver ,  Shannon Casey ,  Deanna Brown ,  Kennon Scott ,  James Harney ,  Dana Ayres ,  Robert Beach ,  Timothy Reed ,  Charles Mauro ,  Lester Miller ,  Fred Williams

IPC分类号： B27J1/02 ,  B27J1/00

CPC分类号： B27J1/02

摘要： A weaving horse assembly for supporting a basket form during construction of a woven basket. The weaving horse assembly comprises a support structure and a clamp arm including a U-shaped frame. The base of the U-shaped frame is rotatably mounted to the support structure such that the clamp arm is movable from a generally vertical position to a generally horizontal position. The U-shaped frame has upper and lower arms each having a free end, with the free end of the lower arm defining a form pole for supporting a basket form and the free end of the upper arm defining a clamp for securing a basket bottom to the basket form.

摘要翻译： 一个编织马组件，用于在编织篮子的建造过程中支撑一个篮子。 编织马组件包括支撑结构和包括U形框架的夹紧臂。 U形框架的基部可旋转地安装到支撑结构上，使得夹持臂可从大致竖直位置移动到大致水平的位置。 U形框架具有上臂和下臂，每个臂具有自由端，下臂的自由端限定用于支撑篮形的支柱，上臂的自由端限定用于将篮底固定到 篮子形式。

公开(公告)号：US20050022660A1

公开(公告)日：2005-02-03

申请号：US10630288

申请日：2003-07-30

申请人： Christopher Holland

发明人： Christopher Holland

IPC分类号： F15B13/04 ,  F15B15/20 ,  F15B11/04

CPC分类号： F15B15/202 ,  F15B13/0406

摘要： A bleed system for venting pressurized gas at a selectively adjustable flow rate. The bleed system includes a plurality of bleed flow paths of different lengths providing varying resistance to the flow of air and a bleed path selector mechanism movable between a plurality of different settings corresponding with the different flow paths. The flow paths are defined by channels formed in a face of a plate and are connectable in series. The bleed system is applied in a runaway control for an air motor which shuts off the motor when its speed exceeds a predetermined cut-off speed. Selection of a different bleed flow path adjusts the cut-off speed.

公开(公告)号：US09425019B1

公开(公告)日：2016-08-23

申请号：US14640655

申请日：2015-03-06

申请人： Sandia Corporation ,  Christopher Holland ,  David Chichester

发明人： Paul J. Resnick ,  Kristin L. Hertz ,  Christopher Holland ,  David Chichester

IPC分类号： H01L29/06 ,  H01J9/02 ,  H01L21/311

CPC分类号： H01J9/02 ,  H01J3/04 ,  H01L21/31111

摘要： An integrated field emission array for ion desorption includes an electrically conductive substrate; a dielectric layer lying over the electrically conductive substrate comprising a plurality of laterally separated cavities extending through the dielectric layer; a like plurality of conically-shaped emitter tips on posts, each emitter tip/post disposed concentrically within a laterally separated cavity and electrically contacting the substrate; and a gate electrode structure lying over the dielectric layer, including a like plurality of circular gate apertures, each gate aperture disposed concentrically above an emitter tip/post to provide a like plurality of annular gate electrodes and wherein the lower edge of each annular gate electrode proximate the like emitter tip/post is rounded. Also disclosed herein are methods for fabricating an integrated field emission array.

公开(公告)号：US20120289800A1

公开(公告)日：2012-11-15

申请号：US13457036

申请日：2012-04-26

申请人： Philip O. Isaacson ,  Bryant Austin Jones ,  Timothy L. Johnson ,  Christopher Holland ,  Matthew Prior

发明人： Philip O. Isaacson ,  Bryant Austin Jones ,  Timothy L. Johnson ,  Christopher Holland ,  Matthew Prior

IPC分类号： A61B5/00 ,  A61B5/01 ,  B23P17/04 ,  A61B5/1455

CPC分类号： A61B5/0008 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/02427 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/6825 ,  A61B5/6838 ,  A61B5/742 ,  Y10T29/49002 ,  Y10T29/49826

摘要： A device includes a clamp and a sensor. The sensor can be attached to the clamp and tissue by the force exerted by the damp. The clamp includes a first jaw member having a jaw face and a second jaw member having a complementary face. The first and second jaw members are held in alignment by a joint. The joint has an elastic member configured to exert a compressive force. The joint allows movement of the jaw face relative to the complementary face in directions corresponding to pitch, roll, yaw, and heave. The compressive force is distributed over a surface of the jaw face. The sensor is coupled to the jaw face or held in place by the compressive force of the jaw face. The sensor is configured to generate a sensor signal corresponding to a physiological parameter of tissue proximate the jaw face.

摘要翻译： 装置包括夹具和传感器。 传感器可以通过潮湿施加的力连接到夹具和组织上。 夹具包括具有钳口面的第一钳口构件和具有互补面的第二钳口构件。 第一和第二钳口构件通过接头保持对准。 接头具有构造成施加压缩力的弹性构件。 该关节允许颚面相对于互补面在与俯仰，滚动，偏转和起伏相对应的方向上移动。 压缩力分布在颌面的表面上。 传感器通过颚面的压缩力联接到颚面或保持在适当位置。 传感器被配置为产生对应于靠近颌面的组织的生理参数的传感器信号。

公开(公告)号：US20120142898A1

公开(公告)日：2012-06-07

申请号：US13368707

申请日：2012-02-08

申请人： David Philip Knight ,  Nicholas James Vavasour Skaer ,  Andrew Michael Collins ,  Tom Louis Dirk Gheysens ,  Christopher Holland

发明人： David Philip Knight ,  Nicholas James Vavasour Skaer ,  Andrew Michael Collins ,  Tom Louis Dirk Gheysens ,  Christopher Holland

IPC分类号： C07K1/02

CPC分类号： A61L27/3687 ,  A61L27/3604 ,  C08H1/00 ,  C08L89/00

摘要： A method for the preparation of a regenerated silk fibroin solution comprises the steps of: treating silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C.; and subsequently degumming the treated silk or silk cocoons; or alternatively, degumming silk or silk cocoons; and subsequently treating the degummed silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C. The invention also extends to fibroin solution, a fibroin material and an implant useful for cartilage repair.

摘要翻译： 一种制备再生丝素蛋白溶液的方法包括以下步骤：用包含一价阳离子和一价阴离子的水溶液的离子试剂处理丝或丝茧，所述阳离子和阴离子的离子半径至少为1.05埃， Jones-Dole B系数在25℃在-0.001和-0.05之间。 然后使经处理的丝或丝茧脱胶; 或者脱胶丝或丝茧; 并随后用包含一价阳离子和一价阴离子水溶液的离子试剂处理脱胶的丝或丝茧，阳离子和阴离子的离子半径至少为1.05埃，琼斯 - 多尔B系数在-0.001-0.05之间 在25℃下。本发明还延伸到丝心蛋白溶液，丝心蛋白材料和用于软骨修复的植入物。

公开(公告)号：US08695206B2

公开(公告)日：2014-04-15

申请号：US13457036

申请日：2012-04-26

申请人： Philip O. Isaacson ,  Bryant Austin Jones ,  Timothy L. Johnson ,  Christopher Holland ,  Matthew Prior

发明人： Philip O. Isaacson ,  Bryant Austin Jones ,  Timothy L. Johnson ,  Christopher Holland ,  Matthew Prior

IPC分类号： H05K13/00 ,  A61B5/1455

CPC分类号： A61B5/0008 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/02427 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/6825 ,  A61B5/6838 ,  A61B5/742 ,  Y10T29/49002 ,  Y10T29/49826

摘要： A device includes a clamp and a sensor. The sensor can be attached to the clamp and tissue by the force exerted by the clamp. The clamp includes a first jaw member having a jaw face and a second jaw member having a complementary face. The first and second jaw members are held in alignment by a joint. The joint has an elastic member configured to exert a compressive force. The joint allows movement of the jaw face relative to the complementary face in directions corresponding to pitch, roll, yaw, and heave. The compressive force is distributed over a surface of the jaw face. The sensor is coupled to the jaw face or held in place by the compressive force of the jaw face. The sensor is configured to generate a sensor signal corresponding to a physiological parameter of tissue proximate the jaw face.

摘要翻译： 装置包括夹具和传感器。 传感器可以通过夹具施加的力连接到夹具和组织。 夹具包括具有钳口面的第一钳口构件和具有互补面的第二钳口构件。 第一和第二钳口构件通过接头保持对准。 接头具有构造成施加压缩力的弹性构件。 该关节允许颚面相对于互补面在与俯仰，滚动，偏转和起伏相对应的方向上移动。 压缩力分布在颌面的表面上。 传感器通过颚面的压缩力联接到颚面或保持在适当的位置。 传感器被配置为产生对应于靠近颌面的组织的生理参数的传感器信号。

公开(公告)号：US08564613B2

公开(公告)日：2013-10-22

申请号：US12794230

申请日：2010-06-04

申请人： Matthew Prior ,  Christopher Larsen ,  Christopher Holland

发明人： Matthew Prior ,  Christopher Larsen ,  Christopher Holland

IPC分类号： G09G5/00

CPC分类号： G06T11/206

摘要： Systems and methods provide a measurement system that modifies the display format based on the type of measurements or and/or the value measured, and these modifications are automatically made based on the information stored within sensors, sensor pods and/or alarm limits.

摘要翻译： 系统和方法提供了一种基于测量类型或/或测量值来修改显示格式的测量系统，并且这些修改是根据存储在传感器，传感器盒和/或报警极限内的信息自动进行的。