-
公开(公告)号：US5571790A
公开(公告)日：1996-11-05
申请号：US472964
申请日：1995-06-07
申请人： Michael Jaye , Wilson Burgess , Thomas Maciag , William N. Drohan
发明人： Michael Jaye , Wilson Burgess , Thomas Maciag , William N. Drohan
CPC分类号： C07K14/501 , A61K38/00 , Y10S930/12
摘要： Endothelial cell growth factor is achieved through the application of recombinant DNA technology to prepare cloning vehicles encoding the ECGF protein and procedures are disclosed for recovering ECGF protein essentially free of other proteins of human origin. The product is useful for, among other purposes, diagnostic applications and as potential in the treatment of damaged blood vessels or other endothelial cell-lined structures.
-
公开(公告)号：US5827826A
公开(公告)日：1998-10-27
申请号：US743261
申请日：1996-11-04
申请人： Michael Jaye , Wilson Burgess , Thomas Maciag , William N. Drohan
发明人： Michael Jaye , Wilson Burgess , Thomas Maciag , William N. Drohan
CPC分类号： C07K14/501 , A61K38/00 , Y10S930/12
摘要： The present invention is directed to compositions comprising endothelial cell growth factor, an acceptable carrier and, optionally, an extracellular matrix protein, a glycosaminoglycan or serum albumin. The compositions are useful for wound repair.
摘要翻译： 本发明涉及包含内皮细胞生长因子，可接受的载体和任选的细胞外基质蛋白，糖胺聚糖或血清白蛋白的组合物。 组合物可用于伤口修复。
-
3.发明授权DNA encoding human endothelial cell growth factors and plasmids comprising said DNA 失效编码人内皮细胞生长因子的DNA和包含所述DNA的质粒
公开(公告)号：US5849538A
公开(公告)日：1998-12-15
申请号：US840088
申请日：1997-04-11
申请人： Michael Jaye , Wilson Burgess , Thomas Maciag , William N. Drohan
发明人： Michael Jaye , Wilson Burgess , Thomas Maciag , William N. Drohan
CPC分类号： C07K14/501 , A61K38/00 , Y10S930/12
摘要： The present invention is directed to DNA encoding human endothelial cell growth factors, and to plasmids comprising said DNA. In particular, the invention relates to DNA encoding a cleavable signal peptide and an endothelial cell growth factor, wherein removal of said signal peptide yields a mature form of the growth factor.
摘要翻译： 本发明涉及编码人内皮细胞生长因子的DNA和包含所述DNA的质粒。 特别地，本发明涉及编码可切割信号肽和内皮细胞生长因子的DNA，其中所述信号肽的去除产生成熟形式的生长因子。
-
公开(公告)号：USRE37850E1
公开(公告)日：2002-09-17
申请号：US09538857
申请日：2000-03-28
IPC分类号： A61K3827
CPC分类号： C07K14/501 , A61K38/00 , Y10S930/12
摘要： Endothelial cell growth factor is achieved through the application of recombinant DNA technology to prepare cloning vehicles encoding the ECGF protein and procedures are disclosed for recovering ECGF protein essentially free of other proteins of human origin. The product is useful for, among other purposes, diagnostic applications and as potential in the treatment of damaged blood vessels or other endothelial cell-lined structures.
摘要翻译： 内皮细胞生长因子通过应用重组DNA技术来制备编码ECGF蛋白质的克隆载体，公开了用于回收基本上不含人源蛋白质的ECGF蛋白质的方法。 该产品除了其它目的之外还可用于诊断应用，并且用于治疗损伤的血管或其它内皮细胞内衬结构的潜力。
-
5.再颁专利DNA encoding human endothelial cell growth factors and plasmids comprising said DNA 失效编码人内皮细胞生长因子的DNA和包含所述DNA的质粒公开(公告)号：USRE38240E1
公开(公告)日：2003-08-26
申请号：US09538305
申请日：2000-03-28
IPC分类号： C12P2104
CPC分类号： C07K14/501 , A61K38/00 , Y02A50/473 , Y10S930/12
摘要： The present invention is directed to DNA encoding human endothelial cell growth factors, and to plasmids comprising said DNA. In particular, the invention relates to DNA encoding a cleavable signal peptide and an endothelial cell growth factor, wherein removal of said signal peptide yields a mature form of the growth factor.
-
公开(公告)号：US4868113A
公开(公告)日：1989-09-19
申请号：US835594
申请日：1986-03-03
申请人： Michael Jaye , Wilson Burgess , Thomas Maciag , William Drohan
发明人： Michael Jaye , Wilson Burgess , Thomas Maciag , William Drohan
IPC分类号： C12N15/09 , A61K38/00 , A61K38/27 , A61P17/00 , A61P43/00 , C07H21/04 , C07K14/00 , C07K14/50 , C07K14/52 , C12N1/19 , C12N1/20 , C12N1/21 , C12N5/10 , C12N15/18 , C12N15/24 , C12N15/74 , C12P21/02 , C12R1/125 , C12R1/19 , C12R1/91
CPC分类号： C07K14/501 , A61K38/00 , Y10S930/12
摘要： Endothelial cell growth factor is achieved through the application of recombinant DNA technology to prepare cloning vehicles encoding the ECGF protein and procedures are disclosed for recovering ECGF protein essentially free of other proteins of human origin. The product is useful for, among other purposes, diagnostic applications and as potential in the treatment of damaged blood vessels or other endothelial cell-line structures.
摘要翻译： 内皮细胞生长因子通过应用重组DNA技术来制备编码ECGF蛋白质的克隆载体，公开了用于回收基本上不含人源蛋白质的ECGF蛋白质的方法。 该产品除了其它目的之外可用于诊断应用，并且用于治疗损伤的血管或其它内皮细胞系结构的潜力。
-
公开(公告)号：US07252799B2
公开(公告)日：2007-08-07
申请号：US09942941
申请日：2001-08-31
申请人： Shirley I. Miekka , Wilson Burgess , William N. Drohan , Martin J. Macphee , Randall S. Kent , David M. Mann , Yuri Griko
发明人： Shirley I. Miekka , Wilson Burgess , William N. Drohan , Martin J. Macphee , Randall S. Kent , David M. Mann , Yuri Griko
IPC分类号： A61K38/46 , A61K39/395
CPC分类号： A61L2/007 , A61K38/38 , A61L2/0011 , A61L2/0035 , A61L2/0041 , A61L2/0047 , A61L2/0052 , A61L2/0058 , A61L2/0064 , A61L2/0082
摘要： Methods are disclosed for sterilizing preparations containing albumin to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. These methods involve sterilizing preparations containing albumin, such as plasma protein fractions, with irradiation.
摘要翻译： 公开了用于灭菌含有白蛋白的制剂的方法，以降低其中的一种或多种活性生物污染物或病原体的水平，例如病毒，细菌（包括细菌和细胞内细菌，如支原体，脲酶，纳米细菌，衣原体，立克次体），酵母 ，霉菌，朊病毒或类似物质，单独或组合，用于TSEs和/或单细胞或多细胞寄生虫。 这些方法包括用照射消毒含有白蛋白的制剂，例如血浆蛋白质级分。
-
公开(公告)号：US06682695B2
公开(公告)日：2004-01-27
申请号：US10197248
申请日：2002-07-18
申请人： Martin MacPhee , William N. Drohan , Randall S. Kent , Tom Lynch , Glenn Calvert , Shirley Miekka , David Mann , Wilson Burgess
发明人： Martin MacPhee , William N. Drohan , Randall S. Kent , Tom Lynch , Glenn Calvert , Shirley Miekka , David Mann , Wilson Burgess
IPC分类号： A61L208
CPC分类号： A61L2/0088 , A23C3/07 , A23C3/076 , A23L3/26 , A23L3/263 , A61L2/0011 , A61L2/0035 , A61L2/0041 , A61L2/0047 , A61L2/0052 , A61L2/0058 , A61L2/0064 , A61L2/007 , A61L2/0082 , A61L2202/22 , A61M1/3681 , A61M1/3683 , A61M1/3686
摘要： Methods are disclosed for sterilizing biological materials to reduce the level of one or more biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, single or multicellular parasites, and/or prions or similar agents responsible, alone or in combination, for TSEs.
-
公开(公告)号：US20110091353A1
公开(公告)日：2011-04-21
申请号：US12959106
申请日：2010-12-02
IPC分类号： A61L2/00
CPC分类号： A61L2/0035 , A61L2/0088
摘要： Methods are disclosed for sterilizing tissue to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria, (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing one or more tissues with irradiation.
摘要翻译： 公开了用于灭菌组织以降低其中的一种或多种活性生物污染物或病原体的水平的方法，例如病毒，细菌（包括细菌和细胞内细菌，如支原体，脲酶原，纳米细菌，衣原体，立克次体），酵母， 对于TSE和/或单细胞或多细胞寄生虫，单独或组合负责的霉菌，真菌，朊病毒或类似物质。 所述方法包括用照射对一个或多个组织进行灭菌。
-
10.发明授权公开(公告)号：US07848487B2
公开(公告)日：2010-12-07
申请号：US12264106
申请日：2008-11-03
IPC分类号： G21K5/00
CPC分类号： C07K16/26 , A61K39/39591 , A61L2/0011 , A61L2/0035 , A61L2/0082 , A61L2/10 , A61L2/16
摘要： Methods are disclosed for sterilizing biological materials to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, nanobacteria, chlamydia, rickettsias), yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing biological materials containing one or more non-aqueous solvents with irradiation.
摘要翻译： 公开了用于灭菌生物材料以减少其中的一种或多种活性生物污染物或病原体的水平的方法，例如病毒，细菌（包括细菌和细胞内细菌，如支原体，尿素原体，纳米细菌，衣原体，立克次体），酵母， 对于TSE和/或单细胞或多细胞寄生虫，单独或组合负责的霉菌，真菌，朊病毒或类似物质。 所述方法包括用辐射对含有一种或多种非水溶剂的生物材料进行灭菌。
-
-
-
-
-
-
-
-
-
搜索结果
28 条记录 (耗时 0.036 秒)
