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公开(公告)号:US08361082B2
公开(公告)日:2013-01-29
申请号:US13037971
申请日:2011-03-01
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
IPC分类号: A61B17/00
CPC分类号: A61B5/064 , A61B5/055 , A61B5/062 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B17/0057 , A61B90/39 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61K49/12 , A61K49/18 , A61K2123/00 , A61M5/007 , A61M37/0069
摘要: A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body so as to at least partially occlude the discharge opening in the distal end section.
摘要翻译: 标记输送装置包括细长的输送套管,其具有与内腔连通的远端部分中的远端部分,内腔和排出口。 至少一个细长的纤维标记物体可滑动地设置在细长的输送套管的内腔内。 所述至少一个细长的纤维标记物主体包括多个生物可吸收的聚合物链。 股线被压缩成压缩构型并且在插入细长的输送套管之前用压缩构型与聚合物粘合剂结合在一起。 可释放插塞设置在内腔的远侧部分内并且远离至少一个细长纤维标记体,以至少部分地封闭远端部分中的排出口。
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公开(公告)号:US08498693B2
公开(公告)日:2013-07-30
申请号:US13082463
申请日:2011-04-08
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
IPC分类号: A61B5/00
CPC分类号: A61B19/54 , A61B17/0057 , A61B90/39 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987
摘要: An elongated intracorporeal remotely detectable marker includes a core of bioabsorbable fibers. An outer jacket of bioabsorbable fibers is disposed around at least part of the core. In one embodiment, for example, the core has a longitudinal extent and a pair of opposed ends, and the outer jacket is disposed around the longitudinal extent of the core, with the pair of opposed ends being exposed.
摘要翻译: 细长的体内可远程检测标记包括生物可吸收纤维的核心。 生物可吸收纤维的外护套设置在芯的至少一部分周围。 在一个实施例中,例如,芯具有纵向范围和一对相对的端部,并且外护套围绕芯的纵向延伸部设置,其一对相对的端部露出。
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公开(公告)号:US20110166448A1
公开(公告)日:2011-07-07
申请号:US13037971
申请日:2011-03-01
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
IPC分类号: A61M25/00
CPC分类号: A61B5/064 , A61B5/055 , A61B5/062 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B17/0057 , A61B90/39 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61K49/12 , A61K49/18 , A61K2123/00 , A61M5/007 , A61M37/0069
摘要: A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body so as to at least partially occlude the discharge opening in the distal end section.
摘要翻译: 标记输送装置包括细长的输送套管,其具有与内腔连通的远端部分中的远端部分,内腔和排出口。 至少一个细长的纤维标记物体可滑动地设置在细长的输送套管的内腔内。 所述至少一个细长的纤维标记物主体包括多个生物可吸收的聚合物链。 股线被压缩成压缩构型并且在插入细长的输送套管之前用压缩构型与聚合物粘合剂结合在一起。 可释放插塞设置在内腔的远侧部分内并且远离至少一个细长纤维标记体,以至少部分地封闭远端部分中的排出口。
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公开(公告)号:US20090171198A1
公开(公告)日:2009-07-02
申请号:US12317339
申请日:2008-12-19
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
CPC分类号: A61B90/39 , A61B2017/00004 , A61B2017/00831 , A61B2017/00898 , A61B2090/0807 , A61B2090/3908 , A61B2090/3925 , A61B2090/3962 , A61B2090/3987
摘要: The marker delivery system described has a delivery tube or cannula which has a bioabsorbable powdered mass and a radiographically detectable element within an inner lumen thereof. The powdered material is a starch such as USP (corn) starch or other suitable polysaccharide. The radiographically detectable element may be disposed within or coupled to a bioabsorbable pellet.
摘要翻译: 所述的标记递送系统具有输送管或插管,其在其内腔内具有生物可吸收的粉末质量和可放射线检测的元件。 粉末材料是淀粉如USP(玉米)淀粉或其它合适的多糖。 可放射线检测的元件可以设置在生物可吸收的颗粒中或与生物可吸收的颗粒结合。
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公开(公告)号:US20090018439A1
公开(公告)日:2009-01-15
申请号:US12214398
申请日:2008-06-18
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
CPC分类号: A61B90/39 , A61B17/0057 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/3954 , A61B2090/3987
摘要: The invention is directed to marker delivery devices and methods of using such devices. The delivery devices embodying features of the invention include a delivery cannula with a discharge opening and a releasable plug disposed in the inner lumen of the delivery cannula so as to at least partially occlude the discharge opening. The releasable plug prevents ingress of tissue, body fluids and the like into the bore of the tube, and prevents the premature discharge of any markers proximal to the releasable plug from passing through the discharge opening before the distal end of the cannula is properly positioned at a desired location within a patient's body. The releasable plug preferably has an MRI detectable element. Preferably, at least one remotely detectable marker mass is provided in the inner lumen of the cannula proximal to the releasable plug.
摘要翻译: 本发明涉及标记物递送装置和使用这种装置的方法。 体现本发明特征的递送装置包括具有放电开口的输送套管和设置在输送插管的内腔中的可释放插塞,以至少部分地封闭排出口。 可释放的塞子防止组织,体液等进入管的孔中,并且防止任何靠近可释放塞的标记的过早排放通过排出口,在套管的远端被适当地定位在 患者体内所需的位置。 可释放插塞优选具有MRI可检测元件。 优选地,至少一个可远程检测的标记物质在靠近可释放塞的插管的内腔中提供。
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公开(公告)号:US07970454B2
公开(公告)日:2011-06-28
申请号:US12214398
申请日:2008-06-18
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
IPC分类号: A61B6/00
CPC分类号: A61B90/39 , A61B17/0057 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/3954 , A61B2090/3987
摘要: The invention is directed to marker delivery devices and methods of using such devices. The delivery devices embodying features of the invention include a delivery cannula with a discharge opening and a releasable plug disposed in the inner lumen of the delivery cannula so as to at least partially occlude the discharge opening. The releasable plug prevents ingress of tissue, body fluids and the like into the bore of the tube, and prevents the premature discharge of any markers proximal to the releasable plug from passing through the discharge opening before the distal end of the cannula is properly positioned at a desired location within a patient's body. The releasable plug preferably has an MRI detectable element. Preferably, at least one remotely detectable marker mass is provided in the inner lumen of the cannula proximal to the releasable plug.
摘要翻译: 本发明涉及标记物递送装置和使用这种装置的方法。 体现本发明特征的递送装置包括具有放电开口的输送套管和设置在输送插管的内腔中的可释放插塞,以至少部分地封闭排出口。 可释放的塞子防止组织,体液等进入管的孔中,并且防止任何靠近可释放塞的标记的过早排放通过排出口,在套管的远端被适当地定位在 患者体内所需的位置。 可释放插塞优选具有MRI可检测元件。 优选地,至少一个可远程检测的标记物质在靠近可释放塞的插管的内腔中提供。
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公开(公告)号:US20110184280A1
公开(公告)日:2011-07-28
申请号:US13082463
申请日:2011-04-08
申请人: Michael L. Jones , Paul Lubock , John Merritt
发明人: Michael L. Jones , Paul Lubock , John Merritt
IPC分类号: A61B6/00
CPC分类号: A61B19/54 , A61B17/0057 , A61B90/39 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987
摘要: An elongated intracorporeal remotely detectable marker includes a core of bioabsorbable fibers. An outer jacket of bioabsorbable fibers is disposed around at least part of the core. In one embodiment, for example, the core has a longitudinal extent and a pair of opposed ends, and the outer jacket is disposed around the longitudinal extent of the core, with the pair of opposed ends being exposed.
摘要翻译: 细长的体内可远程检测标记包括生物可吸收纤维的核心。 生物可吸收纤维的外护套设置在芯的至少一部分周围。 在一个实施例中,例如,芯具有纵向范围和一对相对的端部,并且外护套围绕芯的纵向延伸部设置,其一对相对的端部露出。
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公开(公告)号:US08636637B2
公开(公告)日:2014-01-28
申请号:US13571495
申请日:2012-08-10
申请人: Paul Lubock , Michael L. Jones , Frank R. Louw
发明人: Paul Lubock , Michael L. Jones , Frank R. Louw
IPC分类号: A61N5/00
CPC分类号: A61N5/1014 , A61N5/1002 , A61N5/1015 , A61N2005/1003 , A61N2005/1004 , A61N2005/1005 , A61N2005/1018 , A61N2005/1024
摘要: The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.
摘要翻译: 本公开描述了用于在体腔或部位不对称照射的装置和方法,例如在去除组织之后,例如, 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔,以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度,并且减少或最小化由第二组织部分接收的辐射 (例如健康组织)。
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公开(公告)号:US08626270B2
公开(公告)日:2014-01-07
申请号:US13495408
申请日:2012-06-13
申请人: Fred H. Burbank , Paul Lubock , Michael L. Jones
发明人: Fred H. Burbank , Paul Lubock , Michael L. Jones
CPC分类号: A61B8/481 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/3908 , A61B2090/392 , A61B2090/3925 , A61B2090/395 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61B2090/3995 , A61K49/006 , A61K49/222 , A61M37/0069
摘要: The invention provides materials, devices and methods for marking biopsy sites for a limited time. The biopsy-marking materials are ultrasound-detectable bio-resorbable powders, with powder particles typically between about 20 microns and about 800 microns in maximum dimension, more preferably between about 300 microns and about 500 microns. The powders may be formed of polymeric materials containing cavities sized between about 10 microns and about 500 microns, and may also contain binding agents, anesthetic agents, hemostatic agents, and radiopaque markers. Devices for delivering the powders include tubes configured to contain the powders and to fit within a biopsy cannula, the powders being ejected by action of a syringe. Systems may include a tube containing powder, and a syringe containing sterile saline. The tube may be configured to fit within a biopsy cannula such as a Mammotome® or SenoCor 360™ cannula.
摘要翻译: 本发明提供用于在有限时间内标记活检部位的材料,装置和方法。 活检标记材料是可超声检测的生物可再吸收粉末,粉末颗粒通常在最大尺寸为约20微米至约800微米之间,更优选为约300微米至约500微米。 粉末可以由含有大约10微米至约500微米的空腔的聚合材料形成,并且还可以含有粘合剂,麻醉剂,止血剂和不透射线的标记物。 用于递送粉末的装置包括被配置为容纳粉末并且装配在活检插管内的管,粉末通过注射器的作用喷射。 系统可以包括含有粉末的管和含有无菌盐水的注射器。 管可以被配置成装配在活检插管内,例如Mammotome或SenoCor 360 TM插管。
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公开(公告)号:US08447386B2
公开(公告)日:2013-05-21
申请号:US12967639
申请日:2010-12-14
申请人: Fred H. Burbank , Michael L. Jones , Frank Louw , Paul Lubock
发明人: Fred H. Burbank , Michael L. Jones , Frank Louw , Paul Lubock
CPC分类号: A61B90/39 , A61B2090/3908 , A61B2090/3925 , A61B2090/3933 , A61B2090/3987 , A61K49/226
摘要: A system for at least partially filling and marking a cavity at a site within a patient's body includes a marker delivery device having a chamber configured to contain a marking substance and having a mechanism configured to expel the marking substance. A quantity of the marking substance is contained within the chamber of the marker delivery device. The marking substance is configured to at least partially fill the cavity and form therein a porous bioabsorbable body. A delivery tube is coupled in fluid communication with the chamber of the marker delivery device. The delivery tube has a distal end with a discharge port through which the marking substance is expelled. A releasable remotely detectable distal tip is coupled to the distal end of the delivery tube and is configured to be released to remain within the porous bioabsorbable body within the cavity upon the formation thereof.
摘要翻译: 一种用于至少部分地填充和标记患者体内的部位的空腔的系统包括标记物输送装置,其具有被配置为容纳标记物质并具有被构造成排出标记物质的机构的室。 标记物质的量被容纳在标记物输送装置的室内。 标记物质构造成至少部分地填充空腔并在其中形成多孔生物可吸收体。 输送管与标记物递送装置的腔室流体连通地联接。 输送管具有远端,其具有排出口,排出标记物质。 可释放的可远程检测的远侧末端联接到输送管的远端,并且构造成在其形成时被释放以保持在腔内的多孔生物可吸收体内。
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