公开(公告)号：US20130273308A1

公开(公告)日：2013-10-17

申请号：US13849924

申请日：2013-03-25

申请人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Robin Banerjee

发明人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Robin Banerjee

IPC分类号： B32B5/12 ,  B32B7/00

CPC分类号： B32B5/12 ,  B29C44/1285 ,  B29C44/569 ,  B29C70/083 ,  B29C70/24 ,  B29C70/504 ,  B29C70/865 ,  B32B7/03 ,  E04C2/243 ,  E04C2/246 ,  Y10T156/1075 ,  Y10T428/24132 ,  Y10T428/249953 ,  Y10T428/24996 ,  Y10T428/249981 ,  Y10T428/249982

摘要： A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips, and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins. Continuously wound strips or strip sections may be continuously fed either longitudinally or laterally into molding apparatus which may receive skin materials to form reinforced composite panels.

摘要翻译： 纤维增强芯板由螺旋形缠绕有粗纱层的塑料泡沫条形成，以形成可以以波浪形式延伸或可以与横向腹板相交的腹板。 中空管可以代替泡沫条。 轴向粗纱与上覆的螺旋卷绕粗纱配合以形成梁或柱。 伤口粗纱图案可能随条带而变化，以获得结构效率。 缠绕带可以与间隔的条交替，并且带之间的间隔物增强幅材屈曲强度。 间隔开的条带之间的连续卷绕粗纱允许折叠以形成具有加强边缘的面板。 连续缠绕的条被螺旋缠绕以形成环形结构，并且复合板可以组合热固性树脂和热塑性树脂。 连续缠绕的条带或条形部分可以纵向或横向连续地进给到可以接收表皮材料以形成增强复合板的成型装置中。

公开(公告)号：US20100266833A1

公开(公告)日：2010-10-21

申请号：US11983317

申请日：2007-11-08

申请人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Robin Banerjee

发明人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Robin Banerjee

IPC分类号： B32B3/26 ,  B32B38/00

CPC分类号： B32B5/12 ,  B29C44/1285 ,  B29C44/569 ,  B29C70/083 ,  B29C70/24 ,  B29C70/504 ,  B29C70/865 ,  B32B7/005 ,  E04C2/243 ,  E04C2/246 ,  Y10T156/1075 ,  Y10T428/24132 ,  Y10T428/249953 ,  Y10T428/24996 ,  Y10T428/249981 ,  Y10T428/249982

摘要： A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips, and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins. Continuously wound strips or strip sections may be continuously fed either longitudinally or laterally into molding apparatus which may receive skin materials to form reinforced composite panels.

摘要翻译： 纤维增强芯板由螺旋形缠绕有粗纱层的塑料泡沫条形成，以形成可以以波浪形式延伸或可以与横向腹板相交的腹板。 中空管可以代替泡沫条。 轴向粗纱与上覆的螺旋卷绕粗纱配合以形成梁或柱。 伤口粗纱图案可能随条带而变化，以获得结构效率。 缠绕带可以与间隔的条交替，并且带之间的间隔物增强幅材屈曲强度。 间隔开的条带之间的连续卷绕粗纱允许折叠以形成具有加强边缘的面板。 连续缠绕的条被螺旋缠绕以形成环形结构，并且复合板可以组合热固性树脂和热塑性树脂。 连续缠绕的条带或条形部分可以纵向或横向连续地进给到可以接收表皮材料以形成增强复合板的成型装置中。

公开(公告)号：US20060263387A1

公开(公告)日：2006-11-23

申请号：US11387026

申请日：2006-03-22

申请人： Michael Johnson ,  Jeffrey Hammond ,  Richard McCoy ,  Michael Sheppard

发明人： Michael Johnson ,  Jeffrey Hammond ,  Richard McCoy ,  Michael Sheppard

IPC分类号： A61K39/395 ,  A61K39/12

CPC分类号： C07K14/005 ,  A61K39/00 ,  C07K14/535 ,  C12N15/86 ,  C12N2710/10343 ,  C12N2770/24322 ,  C12N2770/24334

摘要： This invention relates to a recombinant vector including a recombinant porcine adenovirus, stably incorporating and capable of expression of at least one heterologous nucleotide sequence. The nucleotide sequence is preferably one which encodes an antigenic determinant of Hog Cholera Virus or Pseudorabies virus. The further invention relates to a method of production of recombinant vectors, to methods of preparation of vaccines based on the vectors, to administration strategies and to methods of protecting pigs from disease.

公开(公告)号：US4715452A

公开(公告)日：1987-12-29

申请号：US816668

申请日：1986-01-07

申请人： Michael Sheppard

发明人： Michael Sheppard

IPC分类号： E21B7/04

CPC分类号： E21B7/04

摘要： The invention relates to a method of drilling a directional well bore with a drill string. According to the invention, at least a part of the trajectory of the well bore is drilled with a constant build rate so that the part has substantially a constant curvature shape.

摘要翻译： 本发明涉及一种用钻柱钻井定向井的方法。 根据本发明，孔的轨迹的至少一部分以恒定的构造速率钻孔，使得该零件具有基本上恒定的曲率形状。

公开(公告)号：US08727036B2

公开(公告)日：2014-05-20

申请号：US12370903

申请日：2009-02-13

申请人： Ashley Johnson ,  Walter David Aldred ,  Geoffrey Downton ,  Riadh Boualleg ,  Kjell Haugvaldstad ,  Michael Sheppard

发明人： Ashley Johnson ,  Walter David Aldred ,  Geoffrey Downton ,  Riadh Boualleg ,  Kjell Haugvaldstad ,  Michael Sheppard

IPC分类号： E21B7/08 ,  E21B7/04 ,  E21B7/06

CPC分类号： E21B7/06

摘要： This disclosure relates in general to a method and system for controlling a drilling system for drilling a borehole in an earth formation. More specifically, but not by way of limitation, embodiments of the present invention provide systems and methods for controlling dynamic interactions between the drilling system for drilling the borehole and an inner surface of the borehole being drilled to steer the drilling system to directionally drill the borehole. In another embodiment of the present invention, data regarding the functioning of the drilling system as it drills the borehole may be sensed and interactions between the drilling system for drilling the borehole and an inner surface of the borehole may be controlled in response to the sensed data to control the drilling system as the borehole is being drilled.

摘要翻译： 本公开总体上涉及用于控制用于在地层中钻孔的钻井系统的方法和系统。 更具体地但不是限制，本发明的实施例提供了用于控制用于钻孔的钻井系统和钻孔的内表面之间的动态相互作用的系统和方法，用于引导钻井系统以定向钻钻孔 。 在本发明的另一个实施例中，可以感测关于钻井系统在钻孔时的功能的数据，并且可以响应于感测数据来控制用于钻孔和钻孔内表面的钻井系统之间的相互作用 在钻孔时控制钻井系统。

公开(公告)号：US08419883B2

公开(公告)日：2013-04-16

申请号：US11983317

申请日：2007-11-08

申请人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Robin Banerjee

发明人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Robin Banerjee

IPC分类号： B29C65/00 ,  B65H81/00 ,  B32B5/14 ,  B32B7/12

CPC分类号： B32B5/12 ,  B29C44/1285 ,  B29C44/569 ,  B29C70/083 ,  B29C70/24 ,  B29C70/504 ,  B29C70/865 ,  B32B7/005 ,  E04C2/243 ,  E04C2/246 ,  Y10T156/1075 ,  Y10T428/24132 ,  Y10T428/249953 ,  Y10T428/24996 ,  Y10T428/249981 ,  Y10T428/249982

摘要： A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips, and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins. Continuously wound strips or strip sections may be continuously fed either longitudinally or laterally into molding apparatus which may receive skin materials to form reinforced composite panels.

摘要翻译： 纤维增强芯板由螺旋形缠绕有粗纱层的塑料泡沫条形成，以形成可以以波浪形式延伸或可以与横向腹板相交的腹板。 中空管可以代替泡沫条。 轴向粗纱与上覆的螺旋卷绕粗纱配合以形成梁或柱。 伤口粗纱图案可能随条带而变化，以获得结构效率。 缠绕带可以与间隔的条交替，并且带之间的间隔物增强幅材屈曲强度。 间隔开的条带之间的连续卷绕粗纱允许折叠以形成具有加强边缘的面板。 连续缠绕的条被螺旋缠绕以形成环形结构，并且复合板可以组合热固性树脂和热塑性树脂。 连续缠绕的条带或条形部分可以纵向或横向连续地进给到可以接收表皮材料以形成增强复合板的成型装置中。

公开(公告)号：US20110293655A1

公开(公告)日：2011-12-01

申请号：US13109714

申请日：2011-05-17

申请人： Michael Sheppard

发明人： Michael Sheppard

IPC分类号： A61K39/12 ,  A61P31/14 ,  A61P37/04 ,  C12N7/01 ,  C12N15/63

CPC分类号： A61K39/12 ,  A61K2039/5256 ,  A61K2039/543 ,  A61K2039/552 ,  C12N2710/10343 ,  C12N2710/10371 ,  C12N2770/10034

摘要： The invention relates to a porcine adenovirus 3 based vaccine for the treatment of PRRS virus infection where the PADV3 is a recombinant replication competent PADV3 that comprises a nucleic acid that encodes a novel fusion protein of PRRSV ORF6 and a modified PRRSV ORF5 either alone or in combination with a PRRSV ORF.

摘要翻译： 本发明涉及用于治疗PRRS病毒感染的基于猪腺病毒3的疫苗，其中PADV3是重组复制能力的PADV3，其包含编码PRRSV ORF6的新融合蛋白的核酸和单独或组合的修饰的PRRSV ORF5 与PRRSV ORF。

公开(公告)号：US20090044977A1

公开(公告)日：2009-02-19

申请号：US11839381

申请日：2007-08-15

申请人： Ashley Johnson ,  Walter David Aldred ,  Geoffrey Charles Downton ,  Riadh Boualleg ,  Kjell Haugvaldstad ,  Michael Sheppard

发明人： Ashley Johnson ,  Walter David Aldred ,  Geoffrey Charles Downton ,  Riadh Boualleg ,  Kjell Haugvaldstad ,  Michael Sheppard

IPC分类号： E21B7/04 ,  E21B44/00 ,  E21B7/08 ,  G01V3/00

CPC分类号： E21B7/06

摘要： This disclosure relates in general to a method and system for controlling a drilling system for drilling a borehole in an earth formation. More specifically, but not by way of limitation, embodiments of the present invention provide systems and methods for controlling dynamic interactions between the drilling system for drilling the borehole and an inner surface of the borehole being drilled to steer the drilling system to directionally drill the borehole. In another embodiment of the present invention, data regarding the functioning of the drilling system as it drills the borehole may be sensed and interactions between the drilling system for drilling the borehole and an inner surface of the borehole may be controlled in response to the sensed data to control the drilling system as the borehole is being drilled.

摘要翻译： 本公开总体上涉及用于控制用于在地层中钻孔的钻井系统的方法和系统。 更具体地但不是限制，本发明的实施例提供了用于控制用于钻孔的钻井系统和钻孔的内表面之间的动态相互作用的系统和方法，用于引导钻井系统以定向钻钻孔 。 在本发明的另一个实施例中，可以感测关于钻井系统在钻孔时的功能的数据，并且可以响应于感测数据来控制用于钻孔和钻孔内表面的钻井系统之间的相互作用 在钻孔时控制钻井系统。

公开(公告)号：US07393577B2

公开(公告)日：2008-07-01

申请号：US10810298

申请日：2004-03-27

申请人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Paul L. Galloway

发明人： Stephen W. Day ,  G. Scott Campbell ,  Danny E. Tilton ,  Frederick Stoll ,  Michael Sheppard ,  Paul L. Galloway

IPC分类号： B32B3/04 ,  B32B3/26

CPC分类号： B32B5/26 ,  B29C70/24 ,  B29D99/0017 ,  B32B5/02 ,  B32B5/18 ,  B32B5/22 ,  B32B5/245 ,  B32B27/12 ,  B32B2305/022 ,  B32B2305/08 ,  E04C2/246 ,  E04C2/296 ,  E04C2/36 ,  Y10T428/187 ,  Y10T428/237 ,  Y10T428/2419 ,  Y10T428/24207 ,  Y10T428/24231 ,  Y10T428/2424 ,  Y10T428/24248 ,  Y10T428/249924 ,  Y10T428/24996 ,  Y10T428/249981 ,  Y10T428/249986

摘要： A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins.

摘要翻译： 纤维增强芯板由螺旋形缠绕有粗纱层的塑料泡沫条形成，以形成可以以波浪形式延伸或可以与横向腹板相交的腹板。 中空管可以代替泡沫条。 轴向粗纱与上覆的螺旋卷绕粗纱配合以形成梁或柱。 伤口粗纱图案可能随条带而变化，以获得结构效率。 缠绕带可以与间隔开的条带交替，条带之间的间隔物增强幅材屈曲强度。 间隔开的条带之间的连续卷绕粗纱允许折叠以形成具有加强边缘的面板。 连续缠绕的条被螺旋缠绕以形成环形结构，并且复合板可以组合热固性树脂和热塑性树脂。

公开(公告)号：US20070116720A1

公开(公告)日：2007-05-24

申请号：US11586328

申请日：2006-10-25

申请人： Jay Calvert ,  Michael Sheppard ,  Siao-Kun Welch ,  Raymond Rowland ,  Dal-Young Kim

发明人： Jay Calvert ,  Michael Sheppard ,  Siao-Kun Welch ,  Raymond Rowland ,  Dal-Young Kim

IPC分类号： A61K39/395 ,  A61K39/12

CPC分类号： C07K14/005 ,  A61K39/00 ,  A61K2039/525 ,  A61K2039/5254 ,  A61K2039/53 ,  A61K2039/552 ,  A61K2039/55544 ,  A61K2039/55566 ,  A61K2039/55577 ,  C07K2319/42 ,  C07K2319/60 ,  C12N7/00 ,  C12N15/86 ,  C12N2770/10021 ,  C12N2770/10022 ,  C12N2770/10034 ,  C12N2770/10043 ,  C12N2770/10061 ,  G01N33/56983 ,  G01N2333/08

摘要： The invention provides isolated polynucleotide molecules that comprise a DNA sequence encoding an infectious RNA sequence encoding a genetically-modified North American PRRS virus, wherein the polynucleotide molecule lacks at least one detectable antigenic epitope of North American PRRS virus. The invention also provides vaccines comprising genetically modified North American PRRS virus, RNA molecules, plasmids and viral vectors comprising the isolated polynucleotide molecules. Also provided are isolated polynucleotide molecules further comprising at least one nucleotide sequence that encodes a detectable heterologous antigenic epitope, and vaccines comprising North American PRRS virus, RNA molecules, plasmids and viral vectors comprising such isolated polynucleotide molecules.

摘要翻译： 本发明提供了分离的多核苷酸分子，其包含编码编码经遗传修饰的北美PRRS病毒的感染性RNA序列的DNA序列，其中多核苷酸分子缺少至少一种可检测的北美PRRS病毒抗原表位。 本发明还提供包含经遗传修饰的北美PRRS病毒，RNA分子，质粒和包含分离的多核苷酸分子的病毒载体的疫苗。 还提供了进一步包含编码可检测的异源抗原表位的至少一个核苷酸序列的分离的多核苷酸分子，以及包含北美PRRS病毒，RNA分子，质粒和包含这种分离的多核苷酸分子的病毒载体的疫苗。