Nonexpansion Protocol for Autologous Cell-Based Therapies
    9.
    发明申请
    Nonexpansion Protocol for Autologous Cell-Based Therapies 审中-公开
    用于自体细胞治疗的无扩张方案

    公开(公告)号:US20070224173A1

    公开(公告)日:2007-09-27

    申请号:US11567022

    申请日:2006-12-05

    摘要: The present application describes various applications of the non-expansion protocol for the preparation of an injectable autologous cell mixture of the present invention that can be used to prevent symptoms in a number of indications. Cells are isolated from surgically derived tissue and are at least partially disaggregated from each other. The heterologous cell mixture is mixed with growth factors, differentiation agents, extracellular matrix proteins and/or microspheres and injected into the patient without cell expansion. The harvesting of tissue, cell isolation, and injection are performed within a single surgical procedure lasting only minutes to hours.

    摘要翻译: 本申请描述了用于制备可用于预防多种适应症中的症状的本发明的可注射自体细胞混合物的非扩张方案的各种应用。 从手术衍生的组织中分离细胞并且至少部分地彼此分解。 将异源细胞混合物与生长因子,分化剂,细胞外基质蛋白和/或微球体混合,并将其注射到患者体内,无需细胞扩增。 组织的收获,细胞分离和注射在单独的手术过程中进行,持续时间只有几分钟到数小时。