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    Use of oxazolidinone derivatives as anti-penetrating agents in a cosmetic and/or dermatological composition
    1.
    发明授权
    Use of oxazolidinone derivatives as anti-penetrating agents in a cosmetic and/or dermatological composition 失效
    在化妆品和/或皮肤病学组合物中使用恶唑烷酮衍生物作为抗渗透剂

    公开(公告)号：US06255332B1

    公开(公告)日：2001-07-03

    申请号：US08949822

    申请日：1997-10-14

    申请人： Michel Philippe ,  Rémy Tuloup ,  Jean-Luc Morancais

    发明人： Michel Philippe ,  Rémy Tuloup ,  Jean-Luc Morancais

    IPC分类号： A61K3142

    CPC分类号： A61Q17/00 ,  A61K8/49 ,  A61K2800/75 ,  A61K2800/882 ,  A61Q19/00

    摘要： The use of oxazolidinone derivatives in a composition for topical application, especially a cosmetic or dermatological composition, in particular as anti-penetrating agents. These derivatives make it possible especially to prevent the penetration of active agents which are compatible with the skin, the hair and/or mucous membranes, and thus to reduce, or even eliminate altogether, the side effects of these active agents without decreasing their efficacy. Thus, the cosmetic or dermatological compositions containing such active agents make it possible to soften the skin, mucous membranes and the hair.

    摘要翻译： 用于局部应用的组合物中的恶唑烷酮衍生物，特别是化妆品或皮肤病学组合物，特别是作为抗渗透剂。 这些衍生物可以特别地防止与皮肤，毛发和/或粘膜相容的活性剂的渗透，从而降低甚至完全消除这些活性剂的副作用而不降低其功效。 因此，含有这种活性剂的化妆品或皮肤病学组合物可使软化皮肤，粘膜和毛发成为可能。

    Process for limiting the penetration into the skin and/or the keratinous fibres of an active cosmetic and/or pharmaceutical agent
    3.
    发明授权
    Process for limiting the penetration into the skin and/or the keratinous fibres of an active cosmetic and/or pharmaceutical agent 失效
    限制活性化妆品和/或药剂对皮肤和/或角质纤维的渗透的方法

    公开(公告)号：US06497888B1

    公开(公告)日：2002-12-24

    申请号：US09689636

    申请日：2000-10-13

    申请人： Jean-Luc Morancais ,  Michel Philippe

    发明人： Jean-Luc Morancais ,  Michel Philippe

    IPC分类号： A61K600

    CPC分类号： A61K8/14 ,  A61K8/68 ,  A61Q17/04 ,  A61Q19/00

    摘要： A process, composition, and kit for limiting the penetration into the skin and/or the keratinous fibers of at least one cosmetically and/or pharmaceutically active agent present in a base cosmetic and/or pharmaceutical composition for topical application and in particular for reducing the rate of penetration into the skin and/or the keratinous fibers of the active agent(s). The process includes the joint use, with the base composition, of an effective amount of a dispersion of vesicles in a medium, the vesicles comprising at least one ceramide of formula (I): wherein R1 is chosen from saturated and unsaturated, linear and branched C1-C32 alkyl groups optionally substituted by at least one hydroxyl group, wherein said at least one hydroxyl group is optionally esterified by a group chosen from C1-C35 acyls; and R2 is chosen from saturated and unsaturated, linear and branched C1-C50 alkyl groups optionally substituted by at least one hydroxyl groups, and wherein said at least one hydroxyl group is optionally esterified by a group chosen from C1-C30 acyls.

    摘要翻译： 用于限制存在于用于局部应用的基础化妆品和/或药物组合物中的至少一种美容和/或药学活性剂对皮肤和/或角质纤维的渗透的方法，组合物和试剂盒，特别是用于减少 渗透到皮肤和/或活性剂的角质纤维中的速率。 该方法包括与基础组合物共同使用有效量的囊泡在培养基中的分散体，囊泡包含至少一种式（I）的神经酰胺：其中R1选自饱和和不饱和的直链和支链 任选被至少一个羟基取代的C 1 -C 32烷基，其中所述至少一个羟基任选地被选自C 1 -C 35酰基的基团酯化; 并且R 2选自任选被至少一个羟基取代的饱和和不饱和的直链和支链C 1 -C 50烷基，并且其中所述至少一个羟基任选地被选自C 1 -C 30酰基的基团酯化。

    Process for preparing submicron particles in the presence of lipid vesicles, and corresponding compositions
    6.
    发明授权
    Process for preparing submicron particles in the presence of lipid vesicles, and corresponding compositions 失效
    在脂质囊泡存在下制备亚微米颗粒的方法及相应的组合物

    公开(公告)号：US5425993A

    公开(公告)日：1995-06-20

    申请号：US971971

    申请日：1993-02-19

    申请人： Jean-Luc Morancais ,  Alain Lety ,  Guy Vanlerbergue

    发明人： Jean-Luc Morancais ,  Alain Lety ,  Guy Vanlerbergue

    IPC分类号： B01J13/02 ,  A61K8/14 ,  A61K9/127 ,  A61K9/50 ,  A61Q1/02 ,  C09B67/38 ,  C09C3/00 ,  B01J13/20 ,  B01J13/12 ,  G03C1/725

    CPC分类号： A61K8/14 ,  A61K9/127 ,  A61K9/1272 ,  A61Q1/02 ,  A61K2800/43 ,  Y10T428/2984 ,  Y10T428/2987 ,  Y10T428/2989

    摘要： Process for obtaining submicronic particles, for example, pigments in the presence of lipidic vesicles having a lamellar structure, starting with at least one precursor of said particles involves preparing a dispersion of vesicles starting with at least one lipid capable of forming the walls of the vesicles and an aqueous phase E intended to be encapsulated in the said vesicles, and optionally an aqueous phase D, intended to form a dispersion medium of the said vesicles, at least one precursor of the said vesicles being dissolved in phase E and/or D, before and/or during and/or after the preparation of the vesicular phase, at least one agent capable of transforming the said precursor(s) into sought after particles being reacted with it (them) after introduction into the preparation medium.

    摘要翻译： 在具有层状结构的脂质囊泡的存在下获得亚微粒子的方法，从所述颗粒的至少一种前体开始，包括从至少一种能够形成泡囊壁的脂质开始的囊泡分散体 以及旨在包封在所述囊泡中的水相E和任选的水相D，用于形成所述囊泡的分散介质，所述囊泡的至少一种前体溶于E相和/或D相， 在泡囊相的制备之前和/或期间和/或之后，至少一种能够将所述前体转化成所需的颗粒在引入制备介质之后与其反应的至少一种试剂（它们）。

    Process for preparing submicron particles in the presence of lipid vesicles, and corresponding compositions
    7.
    发明授权
    Process for preparing submicron particles in the presence of lipid vesicles, and corresponding compositions 失效
    在脂质囊泡存在下制备亚微米颗粒的方法及相应的组合物

    公开(公告)号：US5670099A

    公开(公告)日：1997-09-23

    申请号：US315869

    申请日：1994-09-30

    申请人： Jean-Luc Morancais ,  Alain Lety ,  Guy Vanlerbergue

    发明人： Jean-Luc Morancais ,  Alain Lety ,  Guy Vanlerbergue

    IPC分类号： B01J13/02 ,  A61K8/14 ,  A61K9/127 ,  A61K9/50 ,  A61Q1/02 ,  C09B67/38 ,  C09C3/00 ,  B01J13/20 ,  B01J13/12 ,  G03C1/725

    CPC分类号： A61K8/14 ,  A61K9/127 ,  A61K9/1272 ,  A61Q1/02 ,  A61K2800/43 ,  Y10T428/2984 ,  Y10T428/2987 ,  Y10T428/2989

    摘要： Process for obtaining submicronic particles, for example, pigments in the presence of lipidic vesicles having a lamellar structure, starting with at least one precursor of said particles involves preparing a dispersion of vesicles starting with at least one lipid capable of forming the walls of the vesicles and an aqueous phase E intended to be encapsulated in the said vesicles, and optionally an aqueous phase D, intended to form a dispersion medium of the said vesicles, at least one precursor of the said vesicles being dissolved in phase E and/or D, before and/or during and/or after the preparation of the vesicular phase, at least one agent capable of transforming the said precursor(s) into sought after particles being reacted with it (them) after introduction into the preparation medium.

    摘要翻译： 在具有层状结构的脂质囊泡的存在下获得亚微粒子的方法，从所述颗粒的至少一种前体开始，包括从至少一种能够形成泡囊壁的脂质开始的囊泡分散体 以及旨在包封在所述囊泡中的水相E和任选的水相D，用于形成所述囊泡的分散介质，所述囊泡的至少一种前体溶于E相和/或D相， 在泡囊相的制备之前和/或期间和/或之后，至少一种能够将所述前体转化成所需的颗粒在引入制备介质之后与其反应的至少一种试剂（它们）。

    Foaming cosmetic cream
    8.
    发明授权
    Foaming cosmetic cream 有权
    发泡美容霜

    公开(公告)号：US06733765B2

    公开(公告)日：2004-05-11

    申请号：US09886216

    申请日：2001-06-22

    申请人： Veronique Guillou ,  Jean-Luc Morancais

    发明人： Veronique Guillou ,  Jean-Luc Morancais

    IPC分类号： A61K700

    CPC分类号： A61Q19/10 ,  A61K8/02 ,  A61K8/046 ,  C11D17/0026

    摘要： A composition including a surfactant in an aqueous medium, wherein said surfactant exhibits at least one paracrystalline phase of either a direct type or a cubic type at temperatures varying from 30° C. to 45° C. inclusive.

    摘要翻译： 一种在水性介质中包含表面活性剂的组合物，其中所述表面活性剂在30℃至45℃的温度范围内显示至少一种直接型或立方型的直晶相。