公开(公告)号：US20170044491A1

公开(公告)日：2017-02-16

申请号：US15118481

申请日：2015-02-13

申请人： NISSAN CHEMICAL INDUSTRIES, LTD. ,  KYOTO UNIVERSITY

发明人： Makiko UMEZAKI ,  Takahiro KISHIOKA ,  Taito NISHINO ,  Ayako OTANI ,  Kenichiro KAMEI ,  Li LIU ,  Yong CHEN

IPC分类号： C12N5/00 ,  D01F1/10 ,  C08L33/12 ,  D04H1/728 ,  D04H1/4291 ,  C08L33/14 ,  D01D5/00 ,  D01F6/36

CPC分类号： C12N5/0068 ,  C08L33/06 ,  C08L33/12 ,  C08L33/14 ,  C08L2201/56 ,  C08L2203/12 ,  C12N2533/40 ,  C12N2537/00 ,  D01D5/003 ,  D01F1/10 ,  D01F6/36 ,  D01F6/52 ,  D04H1/4291 ,  D04H1/728 ,  D10B2509/00

摘要： A composition for producing a fiber, containing (A) a polymer compound containing a unit structure represented by the formula (1) and a unit structure represented by the formula (2), (B) a crosslinking agent, (C) an acid compound, and (D) a solvent wherein each symbol in the formulas (1) and (2) is as described in the DESCRIPTION.

摘要翻译： 其中式（1）和（2）中的每个符号如描述中所述。

公开(公告)号：US20210130757A1

公开(公告)日：2021-05-06

申请号：US17097987

申请日：2020-11-13

申请人： KYOTO UNIVERSITY

发明人： Li LIU ,  Junjun LI ,  Itsunari MINAMI ,  Yong CHEN ,  Norio NAKATSUJI

IPC分类号： C12M3/00 ,  C12M1/12 ,  A61K35/12 ,  C12M1/34 ,  A61F2/24

摘要： Provided is a method for producing a tissue-like construct having cultured cells organized in an aligned manner, especially, a cardiac tissue-like construct. The tissue-like construct prepared by this method is also provided. Further provided are a device for evaluating cellular electrophysiological functions and a method for evaluating cellular electrophysiological functions. Furthermore, a sheet-like cell culture scaffold is also provided.

公开(公告)号：US20170319747A1

公开(公告)日：2017-11-09

申请号：US15522189

申请日：2015-10-30

申请人： KYOTO UNIVERSITY ,  GUNZE LIMITED

发明人： Kenichiro KAMEI ,  Li LIU ,  Norio NAKATSUJI ,  Yong CHEN ,  Hideki SATO ,  Masakazu SUZUKI

IPC分类号： A61L27/38 ,  A61L27/58 ,  C12N5/0735

CPC分类号： A61L27/3834 ,  A61L27/3895 ,  A61L27/58 ,  A61L2300/64 ,  A61L2400/12 ,  A61L2400/18 ,  C12M25/14 ,  C12N5/0068 ,  C12N5/0606 ,  C12N5/0696 ,  C12N2513/00 ,  C12N2533/40 ,  C12N2533/54 ,  C12N2535/00 ,  C12N2537/10

摘要： The present invention provides a cell culture substrate containing a nanofiber composed of a biodegradable polymer on a support composed of a biodegradable polymer. It also provides a method of culturing cells, which includes seeding cells on the substrate, and stationary culture of the cells. Furthermore, the present invention provides an agent for cell transplantation therapy, which contains the substrate and cells cultured on the substrate.