公开(公告)号：US20240000848A1

公开(公告)日：2024-01-04

申请号：US18037630

申请日：2021-11-26

申请人： NOVADIP BIOSCIENCES

发明人： DENIS DUFRANE

IPC分类号： A61K35/28 ,  A61K31/7105 ,  A61P35/00

CPC分类号： A61K35/28 ,  A61K31/7105 ,  A61P35/00

摘要： The present invention relates to a pharmaceutical composition for use in the prevention and/or the treatment of cancer and/or inflammation, comprising (i) a cellular and/or extracellular extract(s) obtained from a scaffold-free 3-dimensional culture of mature cells and a particulate material, wherein the mature cells secreted an extracellular matrix, and wherein the mature cells and the particulate material were embedded in the extracellular matrix; and (ii) a pharmaceutically acceptable excipient.

公开(公告)号：US20220409652A1

公开(公告)日：2022-12-29

申请号：US17781150

申请日：2020-11-27

申请人： NOVADIP BIOSCIENCES

发明人： DENIS DUFRANE

IPC分类号： A61K31/7088 ,  A61P19/08 ,  A61P19/04

摘要： The present invention relates to a pharmaceutical composition comprising a therapeutically effective amount of (i) at least three miRNAs selected in any one of Table 1, Table 2, Table 3, Table 4, Table 5, Table 6, Table 7, Table 8, Table 9, Table 10, Table 11 or Table 12 and (ii) a pharmaceutical acceptable vehicle. The pharmaceutical composition according to the invention may be of therapeutic use for the prevention and/or the treatment of tissue disorders, including, but not limited to skin disorders, bone disorders and/or cartilage disorders.

公开(公告)号：US20240216572A1

公开(公告)日：2024-07-04

申请号：US17781158

申请日：2020-11-27

申请人： NOVADIP BIOSCIENCES

发明人： DENIS DUFRANE ,  Nicolas THEYS

IPC分类号： A61L27/12 ,  A61L27/10 ,  A61L27/26 ,  A61L27/36 ,  A61L27/38 ,  C08L5/04 ,  C08L5/08 ,  C08L5/12 ,  C08L29/04 ,  C08L31/06 ,  C08L39/06 ,  C08L67/04 ,  C08L89/06

CPC分类号： A61L27/12 ,  A61L27/10 ,  A61L27/26 ,  A61L27/3633 ,  A61L27/38 ,  C08L5/04 ,  C08L5/08 ,  C08L5/12 ,  C08L29/04 ,  C08L31/06 ,  C08L39/06 ,  C08L67/04 ,  C08L89/06 ,  A61L2300/414 ,  A61L2430/34

摘要： The present invention relates to sterile and desiccated biomaterials comprising devitalized differentiated cells having tissue regenerating and/or repairing properties, and a particulate material, the cells and the particulate material being embedded in an extracellular matrix. The particulate material is preferably gelatin, a ceramic material, or a demineralized bone matrix (DBM).