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公开(公告)号:US20220403329A1
公开(公告)日:2022-12-22
申请号:US17889776
申请日:2022-08-17
发明人: Yi Zhang , Natalie Artzi , Kui Wang , Eytan Abraham , Yonatan Levinson
摘要: Provided are methods of controlling disassociation of cells from a carrier, compositions, and methods of collecting cells. The methods of controlling disassociation of cells from a carrier may include contacting a polymeric carrier with one or more digesting agents to disassociate at least a portion of a plurality of cells from the polymeric carrier. The polymeric carrier may be crosslinked with a crosslinker including at least one of a redox sensitive moiety, a UV light sensitive moiety, a pH sensitive moiety, and a temperature sensitive moiety.
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公开(公告)号:US11174578B2
公开(公告)日:2021-11-16
申请号:US16301371
申请日:2017-05-11
IPC分类号: B32B3/00 , D04H1/4266 , C09J101/28 , C09J103/02 , C09J105/04 , C09J105/06 , C09J189/06 , D04H1/4218 , D04H1/74 , C09J105/12 , B32B5/12 , B32B5/26 , C08L5/12 , C03C25/26 , B32B19/04 , B32B15/14 , C09J105/00 , B32B37/12 , B32B37/14 , C08J5/24 , D04H1/413 , D04H1/64 , D04H3/002 , E04B1/94 , C03C13/06 , C08L1/28 , C08L3/02 , D04H3/004 , E04B1/88 , A01G24/20 , A01G24/40 , A01G24/15 , A01G24/23 , C09J189/00 , C03C25/32 , C09J11/06 , D04H1/587 , E04B1/74 , C08L89/06 , D04H1/724 , B32B7/12 , B32B37/18 , B32B38/00 , C03C25/321 , C03C25/328 , C09J5/00 , D04H1/4209 , D04H1/593 , E04B1/80 , E04C2/284 , E04D3/35 , E04F13/08 , E04B1/76 , C12N9/06 , C12N9/02 , C12N9/08 , C12N9/10 , C12N9/90
摘要: A method of bonding together surfaces of two or more elements. The method includes the steps of providing two or more elements, applying an adhesive to one or more of the surfaces to be bonded together before, during or after contacting the surfaces to be bonded together with each other, and curing the adhesive, wherein the adhesive comprises at least one hydrocolloid.
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公开(公告)号:US10968285B2
公开(公告)日:2021-04-06
申请号:US16000370
申请日:2018-06-05
发明人: V. Prasad Shastri , Aurelien Forget
IPC分类号: C08B37/00 , A61K31/175 , A61K47/36 , A61L31/12 , C08L5/00 , C12N5/00 , C08B37/08 , C08H1/00 , C08L5/12 , A61K31/715 , A61K8/73 , A61Q90/00 , C10M107/36
摘要: The present invention discloses a matrix comprising a modified polysaccharide consisting of repeating disaccharide units whereby in at least 11% of the disaccharide units one primary alcohol group is oxidized into a carboxylic acid group.
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公开(公告)号:US20200270458A1
公开(公告)日:2020-08-27
申请号:US16281233
申请日:2019-02-21
摘要: The present invention relates to a biodegradable poly-ceramic based on biodegradable formulations for the manufacture of disposable containers of accelerated degradation. These containers have high hardness, high resistance to heat and temperature. Poly-ceramic biodegradable materials are useful for the elaboration of disposable products destined to contain solid food or biological residues of degradation, as well as cold or hot liquids, utensils destined to be discarded or disintegrated as natural nutrients since they are friendly to the environment.
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公开(公告)号:US10752772B1
公开(公告)日:2020-08-25
申请号:US15938027
申请日:2018-03-28
发明人: Joshua M. Kogot , Matthew R. Kincer , April Hirsch
IPC分类号: B33Y70/00 , C08L67/04 , C08L67/02 , C08L71/02 , C08L29/04 , C08L5/06 , C08L3/02 , C08L1/02 , C08K5/00 , C08L5/12 , B29L31/30
摘要: A composition and method are provided for producing a 3-D printable material comprised of a marine biodegradable base polymer and a gelling agent in a ratio preselected to achieve a desired rate of degradation of a structure printed from the material. Suitable polymers include polycaprolactone (PCL), polyhydroxyalkanoate (PHA), or polybutylene succinate (PBS). The gelling agent is typically agar. Faster rates of degradation of the structure are obtained with larger proportions of gelling agent in the composition. The composition may also include biological materials to further promote or control the biodegradation of the structure, and other additives such as nutrients for microorganisms or solidifying agents. 3-D printing of the material occurs at relatively lower temperatures to avoid damage to the biological materials.
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公开(公告)号:US10696882B2
公开(公告)日:2020-06-30
申请号:US15106026
申请日:2014-12-19
发明人: Warren James Grigsby
IPC分类号: C08L97/02 , C08L1/02 , C08L1/08 , C09J189/00 , B27N3/00 , C09J101/02 , C09J105/08 , C09J189/04 , C09J105/06 , C09J105/00 , C09J197/00 , C09J105/04 , C09J103/12 , C09J105/12 , C09J101/28 , C09J103/04 , C09J103/14 , C09J101/08 , C09J103/02 , C08L5/04 , C08L5/00 , C08L3/12 , C08L89/00 , C08L3/14 , C08L5/08 , C08L97/00 , C08L1/28 , C08L89/04 , C08L5/12 , C08L3/04 , C08L3/02 , C08L5/06 , C08J7/04
摘要: An aqueous adhesive composition and a process for preparing such compositions are disclosed. The composition comprises macromolecular complex comprising (A) a first component comprising (i) a framework element and (ii) a polyphenol, and (B) second component comprising a polypeptide, oligopeptide, amino acid, or polyamine. The framework element comprises (a) a polypeptide, oligopeptide, amino acid, or polyamine, (b) a polysaccharide, oligosaccharide, or monosaccharide, or a saccharide conjugate, or (c) a lignin, a lignan or a lignin conjugate. The polyphenol comprises a tannin, a tannic acid, a flavonoid, or a poly-resorcinol. An adhesive precursor composition comprising the first component is also disclosed.
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公开(公告)号:US20200017618A1
公开(公告)日:2020-01-16
申请号:US16470091
申请日:2017-12-06
发明人: Dirk FISCHER , Katharina BERZ , Gundula STARKULLA
IPC分类号: C08F251/00 , A61K8/73 , A61K8/81 , C08L33/26 , C08L5/12
摘要: A water-soluble and/or water-swellable hybrid polymer comprising: (i) from 5 wt.-% to 95 wt.-% water-soluble and/or water-swellable polysaccharide polymer; (ii) from 5 wt.-% to 95 wt.-% synthetic polymer comprising: (a) from 40 mol-% to 99 mol-% of repeating units according to Formula (1) (b) from 0.01 mol-% to 5 mol-% crosslinking or branching units, wherein the crosslinking or branching units result from the incorporation of a monomer comprising at least two olefinically unsaturated double bonds; (c) from 0.99 mol-% to 59.99 mol-% of repeating neutral structural units; wherein components (i) and (ii) are polymerized by radical precipitation polymerization in a polar solvent.
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公开(公告)号:US10336896B2
公开(公告)日:2019-07-02
申请号:US14787041
申请日:2014-04-23
申请人: Jie Zheng , Qiang Chen , Chao Zhao
发明人: Jie Zheng , Qiang Chen , Chao Zhao
摘要: A method of forming a hybrid physically and chemically cross-linked double-network hydrogel with highly recoverable and mechanical properties in a single-pot synthesis is provided. The method comprises the steps of combining the hydrogel precursor reactants into a single pot. The hydrogel precursor reactants include water; a polysaccharide; a methacrylate monomer; an ultraviolet initiator; and a chemical crosslinker. Next the hydrogel precursor reactants are heated to a temperature higher than the melting point of the polysaccharide and this temperature is retained until the polysaccharide is in a sol state. Then the single-pot is cooled to a temperature lower than the gelation point of the polysaccharide and this temperature is retained to form a first network. Thereafter, photo-initiated polymerization of the methacrylate monomer occurs via the ultraviolet initiator to form the second network.
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公开(公告)号:US20180355069A1
公开(公告)日:2018-12-13
申请号:US16000370
申请日:2018-06-05
发明人: V. Prasad SHASTRI , Aurelien FORGET
IPC分类号: C08B37/00 , A61K31/715 , A61Q90/00 , C10M107/36 , A61K47/36 , A61L31/12 , C08L5/00 , C12N5/00 , A23L29/256 , A61K8/73 , C08B37/08 , C08L5/12 , C08H1/00
CPC分类号: C08B37/006 , A23L29/256 , A61K8/73 , A61K31/715 , A61K47/36 , A61L31/125 , A61Q90/00 , C08B37/00 , C08B37/003 , C08B37/0039 , C08B37/0042 , C08B37/0063 , C08B37/0069 , C08B37/0072 , C08B37/0075 , C08H1/00 , C08L5/00 , C08L5/12 , C10M107/36 , C12N5/0068 , C12N2533/50 , C12N2533/70
摘要: The present invention discloses a matrix comprising a modified polysaccharide consisting of repeating disaccharide units whereby in at least 11% of the disaccharide units one primary alcohol group is oxidized into a carboxylic acid group.
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公开(公告)号:US20180231471A1
公开(公告)日:2018-08-16
申请号:US15870146
申请日:2018-01-12
申请人: SFC CO., LTD.
发明人: Moon-Chan Hwang , Jong-Tae Je
CPC分类号: G01N21/80 , C08B37/0039 , C08L5/12 , C09B5/62 , C09B11/02 , C09B23/14 , C09B23/141 , C09B49/10 , C09B57/001 , C09B57/02 , C09B67/0097 , G01N31/221 , G01N33/582 , G01N33/84
摘要: The present disclosure relates to a fluorogenic pH-sensitive dye including an aryl compound having a sulfonyl group (—SO2); and an agarose compound covalently bonded to the sulfonyl group (—SO2) of the aryl compound.
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