摘要:
Compounds of Formula (I) promote axonal outgrowth angiogenesis and can therefore be used to reduce central nerve injuries such as head injury and spinal cord injury, cerebral infarction, ischemic heart diseases, peripheral arterial occlusive diseases, or after-effects of these diseases. in which Nx group is preferably a 6-membered aromatic ring containing two nitrogen atoms; R0, R1 and R2 are each independently a hydrogen atom, an alkyl group, or an amino group; E is an oxygen atom or an —NR8 group (wherein R8 is an alkyl group or the like); n is an integer of of 0 to 5; X and Y are each a connected bond, a cycloalkyl group, or —CO—; and Q is a hydrogen atom or a phenyl group.
摘要翻译:式(I)的化合物促进轴突生长的血管生成,因此可用于减少中枢神经损伤,例如头部损伤和脊髓损伤,脑梗塞,缺血性心脏病,外周动脉闭塞性疾病或这些疾病的后遗症。 其中Nx基团优选为含有两个氮原子的6元芳族环; R 0,R 1和R 2各自独立地为氢原子,烷基或氨基; E是氧原子或-NR8基(其中R8是烷基等); n为0〜5的整数, X和Y各自为连接键,环烷基或-CO-; Q为氢原子或苯基。
摘要:
Provided is a compound that has the ability to promote axonal outgrowth in combination with the ability to promote angiogenesis and can therefore be used to reduce central nerve injuries such as head injury and spinal cord injury, cerebral infarction, ischemic heart diseases such as myocardial infarction and organic angina, peripheral arterial occlusive diseases such as critical limb ischemia, or after-effects of these diseases. Specifically, the compound is represented by the following formula (I): in which Nx group is preferably a 6-membered aromatic ring containing two nitrogen atoms; R0, R1 and R2 are each independently a hydrogen atom, an alkyl group, an amino group or the like; E is an oxygen atom or an —NR8 group (wherein R8 is an alkyl group or the like); n is an integer of 0 to 5; X and Y are each a connecting bond, a cycloalkyl group, —CO— or the like; and Q is a hydrogen atom or a phenyl group.
摘要:
Provided is a compound that has the ability to promote axonal outgrowth in combination with the ability to promote angiogenesis and can therefore be used to reduce central nerve injuries such as head injury and spinal cord injury, cerebral infarction, ischemic heart diseases such as myocardial infarction and organic angina, peripheral arterial occlusive diseases such as critical limb ischemia, or after-effects of these diseases. Specifically, the compound is represented by the following formula (I): in which Nx group is preferably a 6-membered aromatic ring containing two nitrogen atoms; R0, R1 and R2 are each independently a hydrogen atom, an alkyl group, an amino group or the like; E is an oxygen atom or an —NR8 group (wherein R8 is an alkyl group or the like); n is an integer of 0 to 5; X and Y are each a connecting bond, a cycloalkyl group, —CO— or the like; and Q is a hydrogen atom or a phenyl group.
摘要:
It is constructed so as to detect a joint movement position of a robot arm by a position detector and a joint movement speed is calculated from change amounts of the joint movement position and elapsed time and is compared with an allowable movement speed and unlocking and locking of a brake are controlled so that the joint movement speed of an arm at the time of brake unlocking becomes within a constant value even when a shape, an attitude and a load condition of the robot arm vary. Therefore, movement work of the arm by the brake unlocking can be performed alone and a robot with high safety can be obtained.
摘要:
A sub woofer system is constituted of a real time digital signal processing part 5 that includes an A/D converter 5a, a low pass filter block 5b, a delay block 5c, and a D/A converter block 5d, an analog power amplifier 6 and a speaker 7. The length of delay time of the delay block 5c is set so that the length of group delay time of the digital signal processing part 5 may equal an integral multiple of the length of time corresponding to one wavelength of the crossover point frequency between the digital signal processing part 5 and a main speaker 4. The signal processing is performed under the conditions that have been set as such. In this case, a construction is made up wherein the length of a group delay time produced in the digital type real time digital signal processing part can be set to a given value. By this construction, it is possible to provide a sub woofer system which can improve the phase interference between the main speaker and the sub woofer system at the crossover point between the two.
摘要:
The present invention relates to a method for imparting hydrophilicity to a substrate whereby high hydrophilic properties and water-holding properties can be maintained for a long period of time. According to the present invention, an SiO2 film is formed directly or through an undercoat layer on a substrate under a reduced pressure of 100 Pa or less and immediately after the SiO2 film is formed, the SiO2 film is treated with water. Before forming the SiO2 film, it is also desirable that an undercoat layer consisting of a TiO2 film, Al2O3 film, Nb2O5 film, a laminated film prepared by laminating the TiO2 film on the Al2O3 film, a laminated film prepared by laminating the TiO2 film on the Nb2O5 film, or a low emissivity film be formed on a substrate and the SiO2 film be then formed on the undercoat film to serve as an SiO2 composite film.
摘要:
A plurality of solar cell groups having a plurality of solar cells connected to each other electrically in serial. A plurality of diodes are connected to each of the solar cell groups electrically in parallel. The plurality of diodes are sealed between transmissive front surface members and transmissive rear surface members together with the plurality of solar cell groups.
摘要:
A flexible photovoltaic device comprises a first transparent, insulating, and flexible resin layer; a transparent electrode formed on the first resin layer; a flexible resin type locking member formed having satisfactory adherence along the inner periphery of the transparent electrode; a semiconductor layer formed to cover the transparent electrode and the locking member for photoelectric conversion; a back electrode formed on the semiconductor layer; and a second insulating and flexible resin layer formed on the back electrode.
摘要:
In an immersion nozzle for continuous casting, at least one portion of reduced a sectional area of passage for molten metal is formed near to the bottom of the nozzle and plural discharge ports symmetrically arranged with respect to the axis of the nozzle are arranged above and below the reduced sectional area portion in the longitudinal direction of the nozzle. Further, molten metal is continuously cast by using the above immersion nozzle together with a static magnetic field.