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公开(公告)号：US20110091546A1
公开(公告)日：2011-04-21
申请号：US12908225
申请日：2010-10-20
CPC分类号： A61K9/0056 , A61K9/1611 , A61K9/1623 , A61K9/1635 , A61K9/1652
摘要： The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art.The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.
摘要翻译： 与现有技术的快速崩解片剂相比，本发明提供了在口腔中快速崩解片剂在口腔中具有缩短的崩解时间以及足够的硬度。 上述目的通过口腔内快速崩解片剂的组合物来解决，其中组分（a）至（c）以如下方式包含：（a）由甘露糖醇和木糖醇的组合组成的糖类为40〜90重量份 ; （b）无机赋形剂为1〜30重量份; （c）崩解剂为5〜40重量份，条件是（a），（b）和（c）的总量为100重量份。
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公开(公告)号：US08647668B2
公开(公告)日：2014-02-11
申请号：US10576257
申请日：2004-10-14
IPC分类号： A61K9/20
CPC分类号： A61K9/0056 , A61K9/1623 , A61K9/2018
摘要： The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness compared to rapid disintegrating tablets of the prior art. The above objective is solved by a composition in which the inorganic excipient and the disintegrating agent are dispersed in the complex particles consisting of mannitol and other saccharide(s) in a specific ratio, and rapid disintegrating tablets in oral cavity obtained by direct compression of the composition.
摘要翻译： 本发明在口腔中提供了在口腔中具有缩短的崩解时间的快速崩解片剂以及与现有技术的快速崩解片剂相比足够的硬度。 上述目的通过一种组合物来解决，其中无机赋形剂和崩解剂以特定比例分散在由甘露糖醇和其它糖组成的复合颗粒中，并且通过直接压缩获得的口腔中的快速崩解片 组成。
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公开(公告)号：US07838033B2
公开(公告)日：2010-11-23
申请号：US10945049
申请日：2004-09-21
CPC分类号： A61K9/0056 , A61K9/1611 , A61K9/1623 , A61K9/1635 , A61K9/1652
摘要： The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art.The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.
摘要翻译： 与现有技术的快速崩解片剂相比，本发明提供了在口腔中快速崩解片剂在口腔中具有缩短的崩解时间以及足够的硬度。 上述目的通过口腔内快速崩解片剂的组合物来解决，其中组分（a）至（c）以如下方式包含：（a）由甘露糖醇和木糖醇的组合组成的糖类为40〜90重量份 ; （b）无机赋形剂为1〜30重量份; （c）崩解剂为5〜40重量份，条件是（a），（b）和（c）的总量为100重量份。
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公开(公告)号：US08349361B2
公开(公告)日：2013-01-08
申请号：US12908225
申请日：2010-10-20
CPC分类号： A61K9/0056 , A61K9/1611 , A61K9/1623 , A61K9/1635 , A61K9/1652
摘要： The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art.The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.
摘要翻译： 与现有技术的快速崩解片剂相比，本发明提供了在口腔中快速崩解片剂在口腔中具有缩短的崩解时间以及足够的硬度。 上述目的通过口腔内快速崩解片剂的组合物来解决，其中组分（a）至（c）以如下方式包含：（a）由甘露糖醇和木糖醇的组合组成的糖类为40〜90重量份 ; （b）无机赋形剂为1〜30重量份; （c）崩解剂为5〜40重量份，条件是（a），（b）和（c）的总量为100重量份。
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公开(公告)号：US20070275058A1
公开(公告)日：2007-11-29
申请号：US10576257
申请日：2004-10-14
CPC分类号： A61K9/0056 , A61K9/1623 , A61K9/2018
摘要： The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness compared to rapid disintegrating tablets of the prior art. The above objective is solved by a composition in which the inorganic excipient and the disintegrating agent are dispersed in the complex particles consisting of mannitol and other saccharide(s) in a specific ratio, and rapid disintegrating tablets in oral cavity obtained by direct compression of the composition.
摘要翻译： 本发明在口腔中提供了在口腔中具有缩短的崩解时间的快速崩解片剂以及与现有技术的快速崩解片剂相比足够的硬度。 上述目的通过一种组合物来解决，其中无机赋形剂和崩解剂以特定比例分散在由甘露糖醇和其它糖组成的复合颗粒中，并且通过直接压缩获得的口腔中的快速崩解片 组成。
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公开(公告)号：US20050106240A1
公开(公告)日：2005-05-19
申请号：US10945049
申请日：2004-09-21
IPC分类号： A61K9/20 , A61K9/00 , A61K9/16 , A61K9/36 , A61K47/04 , A61K47/10 , A61K47/32 , A61K47/38 , A61K31/045
CPC分类号： A61K9/0056 , A61K9/1611 , A61K9/1623 , A61K9/1635 , A61K9/1652
摘要： The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art. The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.
摘要翻译： 与现有技术的快速崩解片剂相比，本发明提供了在口腔中快速崩解片剂在口腔中具有缩短的崩解时间以及足够的硬度。 上述目的通过口腔内快速崩解片剂的组合物来解决，其中组分（a）至（c）以如下方式包含：（a）由甘露糖醇和木糖醇的组合组成的糖类为40〜90重量份 ; （b）无机赋形剂为1〜30重量份; （c）崩解剂为5〜40重量份，条件是（a），（b）和（c）的总量为100重量份。
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7.发明授权Stable astaxanthin-containing powdery compositions and process for producing the same 有权稳定的含虾青素的粉状组合物及其制造方法公开(公告)号：US07064101B2
公开(公告)日：2006-06-20
申请号：US10472679
申请日：2002-03-22
CPC分类号： C07C403/24 , A23K20/179 , A23K40/10 , A23K50/10 , A23K50/80 , A23L5/44 , A23L7/161 , C09B61/00
摘要： The present invention relates to a stable astaxanthin-containing powdery composition which is obtained by drying a suspension containing a ground Haematococcus alga containing astaxanthin, a surfactant, an antioxidant, an excipient and water and to a process for preparing the same.According to the present invention, there can be provided an astaxanthin-containing powdery composition wherein astaxanthin present in Haematococcus alga has been efficiently stabilized to improve its storage stability for a long term and which is excellent in flowability as a powder, easy to handle and can be easily subjected to solvent extraction without degrading the astaxanthin.
摘要翻译： 本发明涉及一种稳定的含虾青素粉末组合物，其通过干燥含有含有虾青素的地球红藻藻，表面活性剂，抗氧化剂，赋形剂和水的悬浮液及其制备方法而获得。 根据本发明，可以提供含有虾青素的粉末状组合物，其中存在于海藻属藻中的虾青素已被有效地稳定以提高其长期的储存稳定性，并且作为粉末的流动性优异，易于处理并且可以 容易进行溶剂萃取而不降解虾青素。
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公开(公告)号：US20050169780A1
公开(公告)日：2005-08-04
申请号：US11011279
申请日：2004-12-15
申请人： Tadashi Fukami , Koji Onishi , Goro Kakizawa , Koichi Nakatsugi
发明人： Tadashi Fukami , Koji Onishi , Goro Kakizawa , Koichi Nakatsugi
CPC分类号： F04B43/026 , Y10T137/7891
摘要： A pump which has a diaphragm main body integrally connected at a planar portion to a diaphragm portion forming a pump chamber and performs a pumping action by reciprocating a driving portion disposed integrally with the diaphragm portion; the pump being configured compact by disposing a suction valve at the planar portion of the diaphragm main body and further using a planar discharge valve.
摘要翻译： 一种泵，其具有在平面部分处一体地连接到形成泵室的隔膜部分的隔膜主体，并且通过与设置在隔膜部分一体设置的驱动部分往复运动来执行泵送动作; 通过在隔膜主体的平面部分设置吸入阀并进一步使用平面排出阀，将泵构造成紧凑。
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公开(公告)号：US06506033B2
公开(公告)日：2003-01-14
申请号：US09867417
申请日：2001-05-31
申请人： Tadashi Fukami
发明人： Tadashi Fukami
IPC分类号： F04B1700
CPC分类号： F04B43/04 , F04B1/148 , F04B9/042 , F04B43/02 , F04B43/026
摘要： A miniature pump equipped with: a pump chamber communicated with a suction port by way of a check valve and communicated with a discharge port by way of another check valve; a driving portion for performing a pump function by increasing and decreasing a volume of the above described pump chamber; a driving plate attached to the above described driving portion for reciprocating the driving portion; a rotating plate fixed to an output shaft of a motor; a ball disposed at a location which is between the above described driving member and the above described rotating plate, and apart from the above described output shaft; and means for applying a force to a surface of the above described driving plate on a side of the above described rotating plate for bringing the above described driving plate into close contact with the above described ball, in which an inclined direction of the above described driving plate is continuously changed by a movement caused due to rotations and revolutions of the above described ball as the above described rotating plate rotates, thereby reciprocating the above described driving portion and performing a pump function.
摘要翻译： 一种微型泵，其配备有：泵室，其通过止回阀与吸入口连通，并通过另一止回阀与排出口连通; 用于通过增加和减少上述泵室的体积来执行泵功能的驱动部分; 附接到上述驱动部分的驱动板，用于使驱动部分往复运动; 固定到马达的输出轴上的旋转板; 设置在位于上述驱动构件和上述旋转板之间并与上述输出轴分开的位置的球; 以及用于在上述旋转板的一侧向上述驱动板的表面施加力以使上述驱动板与上述球紧密接触的装置，其中上述驾驶的倾斜方向 当上述旋转板旋转时，由于上述球的旋转和转动而导致的板连续变化，从而使上述驱动部分往复运动并执行泵功能。
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公开(公告)号：US06264438B1
公开(公告)日：2001-07-24
申请号：US09246698
申请日：1999-02-09
申请人： Tadashi Fukami
发明人： Tadashi Fukami
IPC分类号： F04B4300
CPC分类号： F04B1/148 , F04B1/295 , F04B43/026 , Y10T74/18336
摘要： A pump includes a pump chamber, a reciprocally, driven body that is moved to perform a pumping function by changing the capacity of the pump chamber, and a driving mechanism that reciprocally moves the driven body. The driving mechanism includes a rotating plate which is fixed to an output shaft of a motor and has an annular groove therein. A ball is sandwiched between an annular groove of a driving plate and the annular groove of the rotating plate. When the rotating plate begins rotating, the ball moves in the annular grooves and changes the inclined direction of the driving plate, thus, causing the driven body to reciprocate.
摘要翻译： 泵包括泵室，通过改变泵室的容量而被移动以执行泵送功能的往复驱动的主体，以及使从动体往复移动的驱动机构。 驱动机构包括固定在电动机的输出轴上的旋转板，其中具有环状槽。 球被夹在驱动板的环形槽和旋转板的环形槽之间。 当旋转板开始旋转时，球在环形槽中移动并改变驱动板的倾斜方向，从而使被驱动体往复运动。
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