公开(公告)号：US20120207992A1

公开(公告)日：2012-08-16

申请号：US13396195

申请日：2012-02-14

申请人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

发明人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

IPC分类号： B32B7/02 ,  C09D163/00 ,  C09D183/04 ,  C09D127/12 ,  B05D5/06 ,  B05D3/00

CPC分类号： G02B1/111 ,  C08G77/26 ,  C09D127/20 ,  C09D183/08 ,  Y10T428/24975 ,  C08K3/36 ,  C08K5/103 ,  C08K13/02

摘要： A production method of an antireflection film comprises, in order, a step of applying a coating composition obtained by mixing the following components (A) to (D) on a base material to form a coating film, a step of drying the coating film to volatilize the solvent therefrom, and a step of curing the coating film to form a cured layer, wherein a multilayer structure having different refractive indexes is formed from the coating composition: (A) a compound having at least one structure selected from a fluorine-containing hydrocarbon structure and a polysiloxane structure and at least one basic functional group, (B) an inorganic fine particle, (C) a curable binder containing no fluorine atom in the molecule, and (D) a solvent, provided that the mass ratio of [component (A)+component (B)]/[component (C)] is from 1/199 to 60/40.

摘要翻译： 防反射膜的制造方法依次包括将通过将下列组分（A）至（D）混合在基材上而获得的涂料组合物涂覆在基材上以形成涂膜的步骤，将涂膜干燥至 使溶剂挥发，并且使涂膜固化形成固化层的步骤，其中由涂料组合物形成具有不同折射率的多层结构体：（A）具有至少一种选自氟 烃结构和聚硅氧烷结构和至少一个碱性官能团，（B）无机细颗粒，（C）分子中不含氟原子的可固化粘合剂和（D）溶剂，条件是质量比[ 组分（A）+组分（B）] / [组分（C）]为1/199至60/40。

公开(公告)号：US20160187540A2

公开(公告)日：2016-06-30

申请号：US13451214

申请日：2012-04-19

申请人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

发明人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

IPC分类号： G02B1/111 ,  B05D3/00 ,  C09D183/04 ,  B05D5/06 ,  B32B5/00

CPC分类号： G02B1/111 ,  B05D3/108 ,  B05D5/00 ,  B05D5/061 ,  B05D5/063 ,  B32B7/02 ,  C08K9/04 ,  C08K9/06 ,  C08L27/12 ,  Y10T428/24975 ,  Y10T428/3154

摘要： The method for producing an antireflection film is provided. The method includes, a step of coating a coating composition including the following components (A) to (D) on a base material to form a coating film, a step of volatilizing the solvent from the coating film for drying the coating film, and a step of curing the coating film to form a cured layer, in which a multilayer structure having different refractive indices from the coating composition is formed: (A) a fluorine-containing polymer with a specific structure, having a polyalkylene oxide group in the molecule, (B) non-surface-modified inorganic fine particles, or inorganic fine particles that are surface-treated with a silane coupling agent having a molecular weight of 600 or less, (C) a curable binder having no fluorine atom in the molecule, and (D) a solvent, provided that the mass ratio of [component (A)+component (B)]/[component (C)] is from 1/199 to 60/40.

摘要翻译： 提供了制造抗反射膜的方法。 该方法包括：将下述成分（A）〜（D）的涂料组合物涂布在基材上形成涂膜的工序，使涂膜干燥后的溶剂挥发的工序，以及 固化涂膜以形成固化层的步骤，其中形成具有与涂料组合物不同的折射率的多层结构：（A）具有特定结构的含氟聚合物，在分子中具有聚环氧烷基团， （B）分子量为600以下的硅烷偶联剂进行表面处理的非表面改性无机微粒或无机微粒，（C）分子中不含氟原子的固化性粘合剂，以及 （D）成分，[成分（A）+成分（B）] / [成分（C）]的质量比为1/199〜60/40。

公开(公告)号：US20120270021A1

公开(公告)日：2012-10-25

申请号：US13451214

申请日：2012-04-19

申请人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

发明人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

IPC分类号： B32B7/02 ,  C09D183/04 ,  B32B5/00 ,  B05D5/06 ,  B05D3/00

CPC分类号： G02B1/111 ,  B05D3/108 ,  B05D5/00 ,  B05D5/061 ,  B05D5/063 ,  B32B7/02 ,  C08K9/04 ,  C08K9/06 ,  C08L27/12 ,  Y10T428/24975 ,  Y10T428/3154

摘要： The method for producing an antireflection film is provided. The method includes, a step of coating a coating composition including the following components (A) to (D) on a base material to form a coating film, a step of volatilizing the solvent from the coating film for drying the coating film, and a step of curing the coating film to form a cured layer, in which a multilayer structure having different refractive indices from the coating composition is formed: (A) a fluorine-containing polymer with a specific structure, having a polyalkylene oxide group in the molecule, (B) non-surface-modified inorganic fine particles, or inorganic fine particles that are surface-treated with a silane coupling agent having a molecular weight of 600 or less, (C) a curable binder having no fluorine atom in the molecule, and (D) a solvent, provided that the mass ratio of [component (A)+component (B)]/[component (C)] is from 1/199 to 60/40.

摘要翻译： 提供了制造抗反射膜的方法。 该方法包括：将下述成分（A）〜（D）的涂料组合物涂布在基材上形成涂膜的工序，使涂膜干燥后的溶剂挥发的工序，以及 固化涂膜以形成固化层的步骤，其中形成具有与涂料组合物不同的折射率的多层结构：（A）具有特定结构的含氟聚合物，在分子中具有聚环氧烷基团， （B）分子量为600以下的硅烷偶联剂进行表面处理的非表面改性无机微粒或无机微粒，（C）分子中不含氟原子的固化性粘合剂，以及 （D）成分，[成分（A）+成分（B）] / [成分（C）]的质量比为1/199〜60/40。

公开(公告)号：US20120207990A1

公开(公告)日：2012-08-16

申请号：US13396135

申请日：2012-02-14

申请人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

发明人： Nobuyuki AKUTAGAWA ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

IPC分类号： B32B7/02 ,  C09D135/02 ,  B05D5/06

CPC分类号： C09D135/02 ,  G02B1/111 ,  Y10T428/2495

摘要： A production method of an antireflection film comprises, in order, a step of applying a coating composition obtained by mixing the following components (A) to (D) on a base material to form a coating film, a step of drying the coating film to volatilize the solvent therefrom, and a step of curing the coating film to form a cured layer, wherein a multilayer structure having different refractive indexes is formed from the coating composition: (A) a compound having at least one structure selected from a fluorine-containing hydrocarbon structure and a polysiloxane structure and at least one isocyanate group; (B) an inorganic fine particle; (C) a curable binder containing no fluorine atom in the molecule; and (D) a solvent; provided that the mass ratio of [component (A)+component (B)]/[component (C)] is from 1/199 to 60/40.

摘要翻译： 防反射膜的制造方法依次包括将通过将下列组分（A）至（D）混合在基材上而获得的涂料组合物涂覆在基材上以形成涂膜的步骤，将涂膜干燥至 使溶剂挥发，并且使涂膜固化形成固化层的步骤，其中由涂料组合物形成具有不同折射率的多层结构体：（A）具有至少一种选自氟 烃结构和聚硅氧烷结构和至少一个异氰酸酯基团; （B）无机细粒; （C）分子中不含氟原子的可固化粘合剂; 和（D）溶剂; 条件是[成分（A）+成分（B）] / [成分（C）]的质量比为1/199〜60/40。

公开(公告)号：US20100246014A1

公开(公告)日：2010-09-30

申请号：US12750804

申请日：2010-03-31

申请人： Miho ASAHI ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

发明人： Miho ASAHI ,  Hiroyuki YONEYAMA ,  Daiki WAKIZAKA

IPC分类号： G02B1/11 ,  B32B27/00 ,  C09D4/00

CPC分类号： G02B1/111 ,  C09D4/00 ,  G02B1/18 ,  G02B5/3033 ,  G02B27/0006 ,  Y10T428/249974 ,  Y10T428/25 ,  Y10T428/31544

摘要： An antireflective film includes: a transparent substrate film; and at least one low refractive index layer, the low refractive index layer is formed with a composition containing: a fluorine-containing antifouling agent having a weight average molecular weight of less than 10,000 and a structure represented by the following formula (F); a polyfunctional monomer having a polymerizable unsaturated group; and (C) an inorganic particle, and a content of the fluorine-containing antifouling agent is 1% by weight or more and less than 25% by weight based on a total solid content of the coating composition: (Rf)-[(W)-(RA)n]m  Formula (F) wherein, Rf represents a (per)fluoroalkyl group or a (per)fluoropolyether group, W represents a connecting group, RA represents a functional group having a polymerizable unsaturated group, n represents an integer of from 1 to 3, and m represents an integer of from 1 to 3.

摘要翻译： 防反射膜包括：透明基板膜; 和至少一个低折射率层，低折射率层由含有重均分子量小于10,000的含氟防污剂和由下式（F）表示的结构的组合物形成; 具有聚合性不饱和基团的多官能单体; 和（C）无机颗粒，并且含氟防污剂的含量相对于涂料组合物的总固体含量为1重量％以上且小于25重量％：（Rf） - [（W ） - （RA）n] m式（F）其中，Rf表示（全）氟烷基或（全）氟聚醚基，W表示连接基，RA表示具有可聚合不饱和基的官能团，n表示 1〜3的整数，m表示1〜3的整数。

公开(公告)号：US20100245722A1

公开(公告)日：2010-09-30

申请号：US12749701

申请日：2010-03-30

申请人： Hiroyuki YONEYAMA ,  Jun Watanabe

发明人： Hiroyuki YONEYAMA ,  Jun Watanabe

IPC分类号： G02F1/1335 ,  G02B5/02 ,  G02B5/30 ,  B32B3/30 ,  B32B5/02

CPC分类号： G02B5/02 ,  Y10T428/24612

摘要： A light-transmitting substrate has an uneven profile on at least one surface thereof, the light-transmitting substrate contains a thermoplastic resin and a flat translucent particle; a tilt angle of the uneven profile on at least one surface of the light-transmitting substrate has the following distribution: (a) an integral value of frequencies of from 0° to less than 1.0° is from 0% to less than 25%, (b) an integral value of frequencies of from 1.0° to less than 10° is from 60% to less than 100%, and (c) an integral value of frequencies of 10° or more is from 0% to less than 25%, and an average distance between trough and crest in the uneven profile is from 10 to 300 μm.

摘要翻译： 透光基板在其至少一个表面上具有不均匀的轮廓，透光基板包含热塑性树脂和平坦的半透明颗粒; 在透光基板的至少一个表面上的不平坦轮廓的倾斜角度具有以下分布：（a）从0°至小于1.0°的频率的积分值为0％至小于25％， （b）从1.0°至小于10°的频率的积分值为60％至小于100％，（c）10°或更高频率的积分值为0％至小于25％ ，不平坦轮廓中的槽和波峰之间的平均距离为10〜300μm。

公开(公告)号：US20100245715A1

公开(公告)日：2010-09-30

申请号：US12749916

申请日：2010-03-30

申请人： Jun WATANABE ,  Hiroyuki YONEYAMA ,  Takato SUZUKI

发明人： Jun WATANABE ,  Hiroyuki YONEYAMA ,  Takato SUZUKI

IPC分类号： G02F1/1335 ,  G02B5/02 ,  G02B1/12 ,  G02B5/30 ,  B05D5/06

CPC分类号： G02B5/02 ,  G02F1/133502

摘要： In a method for making an antiglare film including the casting, the releasing, the drying, the applying and the curing as defined herein, the transparent particles have an average primary particle size of greater than 2.5 μm and not greater than 12 μm, the transparent base has on at least one side thereof flat portions substantially parallel to a film-forming plane and rounded protrusions arising from the transparent particles, the protrusions having a maximum height Rt from the flat portions of from 1 to 15 μm, and the cured layer has an average thickness of from 1 to 15.0 μm and a surface profile with an arithmetic average roughness Ra, a mean spacing between peaks Sm, and an average slope θa, all as measured in accordance with JIS B0601, satisfying the relationships (1) to (3) as defined herein.

摘要翻译： 在制造包括如本文所定义的浇铸，脱模，干燥，施加和固化的防眩膜的方法中，透明颗粒的平均一次粒径大于2.5μm且不大于12μm，透明 基底的至少一侧的平坦部分基本上平行于成膜平面和由透明颗粒产生的圆形突起，突起具有从1至15μm的平坦部分的最大高度Rt，并且固化层具有 平均厚度为1至15.0μm，具有算术平均粗糙度Ra，平均间距Sm和平均斜率等的表面轮廓; a，根据JIS B0601测量的全部满足关系式（1） 至（3）。

公开(公告)号：US20080118669A1

公开(公告)日：2008-05-22

申请号：US11943442

申请日：2007-11-20

申请人： Rikio INOUE ,  Hiroyuki YONEYAMA ,  Hiroyuki MIFUNE

发明人： Rikio INOUE ,  Hiroyuki YONEYAMA ,  Hiroyuki MIFUNE

IPC分类号： C09K19/00 ,  B32B9/04

CPC分类号： G02B1/111 ,  G02B2207/121 ,  Y10T428/1036 ,  Y10T428/1041 ,  Y10T428/1055 ,  Y10T428/24942 ,  Y10T428/31504

摘要： An antireflective film is provided and includes: a transparent substrate; at least one conductive layer formed from a composition including at least one transparent conductive polymeric material and a compound forming a cross-liking site, the compound having a plurality of cross-linking reactive groups, at least one of which cross-links with the transparent conductive polymeric material; and at least one low refractive index layer.

摘要翻译： 提供防反射膜，包括：透明基板; 由包含至少一种透明导电聚合物材料和形成交叉嵌合位点的化合物的组合物形成的至少一个导电层，所述化合物具有多个交联反应性基团，其中至少一个与透明 导电聚合材料; 和至少一个低折射率层。

公开(公告)号：US20080069975A1

公开(公告)日：2008-03-20

申请号：US11898022

申请日：2007-09-07

申请人： Shinya KATO ,  Shunichi KONDO ,  Hiroyuki YONEYAMA ,  Tetsuya ASAKURA ,  Ryo SATAKE

发明人： Shinya KATO ,  Shunichi KONDO ,  Hiroyuki YONEYAMA ,  Tetsuya ASAKURA ,  Ryo SATAKE

IPC分类号： C09K19/00 ,  B32B5/16

CPC分类号： C08G73/02 ,  G02B1/105 ,  G02B1/14 ,  G02B5/0226 ,  G02B5/0242 ,  G02B5/0278 ,  Y10T428/1041 ,  Y10T428/25

摘要： An optical film comprises: a transparent support; and a hardcoat layer comprising a heat- and/or ionizing radiation-curable resin and an organic resin particle having a refractive index of 1.60 or more, wherein a percentage change in an entire beam transmittance between before and after the optical film is exposed to an environment at a temperature of 80° C. and a relative humidity of 90% for 500 hours is 5% or less.

摘要翻译： 光学膜包括：透明支撑体; 以及包含热和/或电离辐射固化树脂和折射率为1.60以上的有机树脂颗粒的硬涂层，其中光学膜之前和之后的整个光束透射率的百分比变化暴露于 温度80℃，相对湿度90％，500小时的环境为5％以下。

公开(公告)号：US20120076793A1

公开(公告)日：2012-03-29

申请号：US13309100

申请日：2011-12-01

申请人： Hiroyuki YONEYAMA ,  Takafumi ICHIDA ,  Shosaku NARUMI

发明人： Hiroyuki YONEYAMA ,  Takafumi ICHIDA ,  Shosaku NARUMI

IPC分类号： A61K39/395 ,  A61P1/16

CPC分类号： C07K16/24 ,  A61K2039/505

摘要： The present invention aims at providing a medicament and a method for promoting replication of hepatocytes and a medicament and a method for ameliorating insulin resistance.An effective amount of a neutralizing agent for CXCL10 belonging to a subfamily of chemokines which are heparin-binding proteins is administered to the hepatocytes to promote the replication of the hepatocytes. As the neutralizing agent for CXCL10, a factor which is specifically bound to CXCL10 and inhibits an activity of CXCL10 or a factor which inhibits CXCL10 expression is suitably used. By administering the neutralizing agent to impaired hepatic tissue, it is possible to restore and regenerate the hepatic tissue. Meanwhile, by administering an effective amount of the neutralizing agent for CXCL10 to the hepatocytes, the insulin resistance in type II diabetes and metabolic syndrome is ameliorated.

摘要翻译： 本发明的目的在于提供促进肝细胞复制的药物和方法，以及用于改善胰岛素抵抗的药物和方法。 向肝细胞施用有效量的属于肝素结合蛋白的趋化因子亚类的CXCL10的中和剂，以促进肝细胞的复制。 作为CXCL10的中和剂，适当使用与CXCL10特异性结合并抑制CXCL10活性或抑制CXCL10表达的因子的因子。 通过将中和剂施用于肝组织损伤，可以恢复和再生肝组织。 同时，通过向肝细胞施用有效量的CXCL10中和剂，可以改善II型糖尿病和代谢综合征中的胰岛素抵抗。