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公开(公告)号：US11643563B2
公开(公告)日：2023-05-09
申请号：US16317073
申请日：2017-07-13
Applicant: NORTH CAROLINA STATE UNIVERSITY
Inventor： Orlin D. Velev , Sangchul Roh
IPC: C09D11/102 , B33Y10/00 , B33Y70/00 , B29C64/106 , C09D11/36 , C09D11/38 , C08L83/04 , C09D11/322 , C09D11/40 , C09D11/54 , B29K83/00
CPC classification number: C09D11/102 , B29C64/106 , B33Y10/00 , B33Y70/00 , C08L83/04 , C09D11/322 , C09D11/36 , C09D11/38 , C09D11/40 , C09D11/54 , B29K2083/00
Abstract: The present disclosure relates to compositions and methods for three-dimensional printing.
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公开(公告)号：US20190281833A1
公开(公告)日：2019-09-19
申请号：US16358643
申请日：2019-03-19
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Alexander P. Richter
IPC: A01N59/16
Abstract: This invention is directed to the preparation and applications of internally and/or externally functionalized environmentally benign nanoparticles (EbNPs), which are produced by a three step procedure: (1) synthesis of native EbNPs, (2) functionalization with active agents, and (3) additional surface property customization via one or more modifier(s).
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公开(公告)号：US12209203B2
公开(公告)日：2025-01-28
申请号：US17699006
申请日：2022-03-18
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Sangchul Roh
IPC: C09D7/40 , C08K7/02 , C09D5/00 , C09D7/65 , C09D101/12 , C09D101/28 , C09D125/06 , C09D129/04 , C09D181/06 , C09K3/00
Abstract: Fractal-like polymeric particles having a hierarchical, branched structure are disclosed. The particles have fibers with nanometer-scale diameters on their peripheries, which enables a number of unique and highly desirable properties. The particles are fabricated by a method combining phase separation and shear forces of different solutions, in particular a polymer solution. In addition, the particles may be used as coatings, nonwovens, textiles and viscosity modifiers and adhesives, among other applications.
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公开(公告)号：US20200163656A1
公开(公告)日：2020-05-28
申请号：US16618734
申请日：2018-06-02
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Timothy W. Shay , Michael D. Dickey
Abstract: Microfluidic devices are provided for continuous sampling of biological fluid for extended periods of time, e.g. for periods of time up to and including 10 days. The microfluidic devices can be made from porous hydrophilic substrate, e.g. hydrophilic paper substrates. The devices can include a collection pad, an evaporative pump, and a channel connecting the collection pad and the evaporative pump. Hydrogels at the collection pad can promote collection of sweat or other biological fluids from a subject, which in some aspects is assisted by the use of one or more microneedles on the substrate. An evaporative pump can provide for long periods of sampling by providing continual pumping, e.g. through the use of an evaporation pad where sampled fluid can evaporate.
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公开(公告)号：US20140256545A1
公开(公告)日：2014-09-11
申请号：US14202259
申请日：2014-03-10
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Alexander P. Richter
Abstract: This invention is directed to the preparation and applications of internally and/or externally functionalized environmentally benign nanoparticles (EbNPs), which are produced by a three step procedure: (1) synthesis of native EbNPs, (2) functionalization with active agents, and (3) additional surface property customization via one or more modifier(s).
Abstract translation: 本发明涉及内部和/或外部功能化的环境友好纳米颗粒（EbNP）的制备和应用，其通过三步法制备：（1）天然EbNP的合成，（2）用活性剂的功能化和（ 3）通过一个或多个修饰符定制额外的表面属性。
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Patent Agency Ranking
6.发明公开公开(公告)号：US20230145146A1
公开(公告)日：2023-05-11
申请号：US17980807
申请日：2022-11-04
Applicant: North Carolina State University , Eastman Chemical Company
Inventor： Orlin D. Velev , Lokendra Pal , Sachin Agate , Austin Williams , Joseph Dougherty
IPC: G01N21/31
CPC classification number: G01N21/31
Abstract: The present invention provides a method for directly measuring the color of transparent polymer particles. A composite liquid, comprising a transparent liquid with nanoparticles and matching the refractive index of the polymer, can be used to mitigate the light scattering due to the roughness of the particles surface. The method can be applied to copolyester particles, such as copolyester pellets.
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公开(公告)号：US10278395B2
公开(公告)日：2019-05-07
申请号：US14202259
申请日：2014-03-10
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Alexander P. Richter
Abstract: This invention is directed to the preparation and applications of internally and/or externally functionalized environmentally benign nanoparticles (EbNPs), which are produced by a three step procedure: (1) synthesis of native EbNPs, (2) functionalization with active agents, and (3) additional surface property customization via one or more modifier(s).
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公开(公告)号：US20240076509A1
公开(公告)日：2024-03-07
申请号：US17699006
申请日：2022-03-18
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Sangchul Roh
IPC: C09D7/40 , C08K7/02 , C09D5/00 , C09D7/65 , C09D101/12 , C09D101/28 , C09D125/06 , C09D129/04 , C09D181/06
CPC classification number: C09D7/70 , C08K7/02 , C09D5/00 , C09D7/65 , C09D101/12 , C09D101/28 , C09D125/06 , C09D129/04 , C09D181/06 , C09K3/00
Abstract: Fractal-like polymeric particles having a hierarchical, branched structure are disclosed. The particles have fibers with nanometer-scale diameters on their peripheries, which enables a number of unique and highly desirable properties. The particles are fabricated by a method combining phase separation and shear forces of different solutions, in particular a polymer solution. In addition, the particles may be used as coatings, nonwovens, textiles and viscosity modifiers and adhesives, among other applications.
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9.发明公开公开(公告)号：US20240000346A1
公开(公告)日：2024-01-04
申请号：US18217392
申请日：2023-06-30
Applicant: North Carolina State University
Inventor： Tamoghna Saha , Orlin D. Velev , Michael D. Dickey , Michael Daniele
IPC: A61B5/145 , A61B5/1473
CPC classification number: A61B5/14514 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1473 , A61B2505/07 , A61B2560/063
Abstract: Various examples are provided related to interstitial fluid (ISF) or extracellular fluid (ECF) harvesting and processing. In one example, a microfluidic monitoring platform includes a microneedle patch including microneedles on a first side; an osmotic patch on a second side of the microneedle patch that includes glycerogel or hydrogel equilibrated with glycerin or glucose; and a microfluidic or fluid transport film or material channel between the osmotic patch and the microneedle patch. The channel can extract fluid from the osmotic-microneedle patch complex. In another example, a wearable electrochemical sensing system includes a monitoring platform including a microneedle-osmotic patch, a microfluidic or fluid transport film or material channel, and at least one sensor between the channel; and processing circuitry coupled to the at least one sensor. The processing circuitry can monitor presence of a chemical or biomarker in the fluid based upon signals obtained from the sensor.
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公开(公告)号：US20220235188A1
公开(公告)日：2022-07-28
申请号：US17584569
申请日：2022-01-26
Applicant: North Carolina State University
Inventor： Orlin D. Velev , Yosra Kotb
Abstract: Provided is a biopolymer composite film that includes a polysaccharide matrix reinforced with soft dendritic colloids and methods for making. The method can include dissolving agarose in water to form a first mixture, mixing nanofibrillated chitosan in the agarose, sonicating or stirring the mixture to form a homogeneous second mixture, casting the second mixture, and gelling the second mixture to form a film. Also provided is a food or consumer product packaging film that includes the biopolymer composite film.
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