公开(公告)号：US20170165932A1

公开(公告)日：2017-06-15

申请号：US15376708

申请日：2016-12-13

Applicant: Novartis AG

Inventor： Xinming Qian ,  Jared Nelson ,  Robert Carey Tucker ,  Steve Yun Zhang ,  Daqing Wu ,  Leroy Wainaina Muya ,  Dharmesh Patel ,  Zach Munoz ,  Yongxing Qiu ,  Chung-Yuan Chiang ,  Ritu Shrestha ,  Kelly Kayi Tallau

IPC: B29D11/00 ,  G02C7/04 ,  G02B1/04

CPC classification number: B29D11/00865 ,  B29D11/00038 ,  B29D11/00144 ,  B29D11/0025 ,  B29K2083/00 ,  B29K2105/0002 ,  B29K2105/0061 ,  B29K2995/0092 ,  G02B1/043 ,  G02C7/049 ,  G02C2202/16

Abstract: The present invention generally relates to a method for producing silicone hydrogel contact lenses having a stable lubricious coating thereon without involving use of organic solvent in post-curing processes.

公开(公告)号：US10968319B2

公开(公告)日：2021-04-06

申请号：US16281400

申请日：2019-02-21

Applicant: Novartis AG

Inventor： Steve Yun Zhang ,  Maria F. Gubitosi Raspino ,  Richard Charles Breitkopf ,  Daqing Wu ,  Junhao Ge ,  Augustine Twum Kumi ,  Zach Munoz ,  Weihong Lang

IPC: G02B1/04 ,  C08G77/442 ,  C08J3/24 ,  B29D11/00 ,  B29K83/00

Abstract: The present invention generally relates to silicone hydrogel contact lenses each inherently having, on lens surfaces, a relatively-high concentration of primary amino groups and to a method for producing the same. The invention is also related to silicone hydrogel contact lens precursors each inherently having, on lens surfaces, a relatively-high concentration of N-Boc-protected primary amino groups which can be easily and conveniently deprotected during lens extraction and/or hydration steps.

公开(公告)号：US10449740B2

公开(公告)日：2019-10-22

申请号：US15376708

申请日：2016-12-13

Applicant: Novartis AG

Inventor： Xinming Qian ,  Jared Nelson ,  Robert Carey Tucker ,  Steve Yun Zhang ,  Daqing Wu ,  Leroy Wainaina Muya ,  Dharmesh Patel ,  Zach Munoz ,  Yongxing Qiu ,  Chung-Yuan Chiang ,  Ritu Shrestha ,  Kelly Kayi Tallau

IPC: B29D11/00 ,  G02B1/04 ,  G02C7/04 ,  B29K83/00 ,  B29K105/00

Abstract: The present invention generally relates to a method for producing silicone hydrogel contact lenses having a stable lubricious coating thereon without involving use of organic solvent in post-curing processes.

公开(公告)号：US20180356562A1

公开(公告)日：2018-12-13

申请号：US16000930

申请日：2018-06-06

Applicant: Novartis AG

Inventor： Daqing Wu ,  Junhao Ge ,  Steve Yun Zhang ,  Richard Charles Breitkopf ,  Xinming Qian ,  Zach Munoz ,  Matthew D. Nelson ,  Augustine Twum Kumi ,  Weihong Lang ,  Ying Zheng ,  Feng Jing ,  Frank Chang

IPC: G02B1/04 ,  C08L83/04

CPC classification number: G02B1/043 ,  B29D11/00134 ,  C08F230/08 ,  C08L83/04

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.

公开(公告)号：US20180355112A1

公开(公告)日：2018-12-13

申请号：US16000933

申请日：2018-06-06

Applicant: Novartis AG

Inventor： Steve Yun Zhang ,  Daqing Wu ,  Junhao Ge ,  Richard Charles Breitkopf ,  Xinming Qian ,  Zach Munoz ,  Matthew D. Nelson ,  Augustine Twum Kumi ,  Weihong Lang ,  Ying Zheng ,  Feng Jing ,  Frank Chang

IPC: C08G77/442 ,  C08G77/20 ,  C08G77/388 ,  C08G77/392 ,  C08G77/14 ,  C08G77/12 ,  C08L83/10 ,  G02B1/04

CPC classification number: C08G77/442 ,  B29D11/00134 ,  C08G77/12 ,  C08G77/14 ,  C08G77/20 ,  C08G77/388 ,  C08G77/392 ,  C08G2210/00 ,  C08L83/10 ,  C08L2201/10 ,  G02B1/043 ,  G02B2207/109 ,  G02C7/04

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.

公开(公告)号：US20190263971A1

公开(公告)日：2019-08-29

申请号：US16281400

申请日：2019-02-21

Applicant: Novartis AG

Inventor： Steve Yun Zhang ,  Maria F. Gubitosi Raspino ,  Richard Charles Breitkopf ,  Daqing Wu ,  Junhao Ge ,  Augustine Twum Kumi ,  Zach Munoz ,  Weihong Lang

IPC: C08G77/442 ,  G02B1/04 ,  C08J3/24 ,  B29D11/00

Abstract: The present invention generally relates to silicone hydrogel contact lenses each inherently having, on lens surfaces, a relatively-high concentration of primary amino groups and to a method for producing the same. The invention is also related to silicone hydrogel contact lens precursors each inherently having, on lens surfaces, a relatively-high concentration of N-Boc-protected primary amino groups which can be easily and conveniently deprotected during lens extraction and/or hydration steps.

公开(公告)号：US20180354214A1

公开(公告)日：2018-12-13

申请号：US16000928

申请日：2018-06-06

Applicant: Novartis AG

Inventor： Daqing Wu ,  Steve Yun Zhang ,  Xinming Qian ,  Zach Munoz ,  Frank Chang ,  Wei Liang ,  Ying Zheng ,  Richard Charles Breitkopf ,  Matthew D. Nelson ,  Augustine Twum Kumi

IPC: B29D11/00 ,  G02B1/04

CPC classification number: B29D11/00134 ,  B29D11/00067 ,  B29D11/00076 ,  C08G77/442 ,  C08L83/04 ,  G02B1/043

Abstract: The present invention generally relates to a method for producing inherently wettable silicone hydrogel contact lenses with a robusteness of lens shape and having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus.