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公开(公告)号：US20130183389A1
公开(公告)日：2013-07-18
申请号：US13805040
申请日：2011-06-20
IPC分类号： A61K33/14
CPC分类号： A61K33/14 , A61K9/0029 , A61K9/0095 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/00 , A61K33/06 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含氯化钠，至少一种干酸和至少一种镁盐，以及任选的钾盐，钙盐和葡萄糖的粉末组分组成。 根据本发明，所述至少一种镁盐和所述任选的葡萄糖以所述透析酸前体组合物中的无水组分存在。
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公开(公告)号：US20130189376A1
公开(公告)日：2013-07-25
申请号：US13805474
申请日：2011-06-20
IPC分类号： A61K33/14 , A61K31/19 , A61K31/7004 , A61K31/191 , A61K31/194
CPC分类号： A61K33/14 , A61K9/0029 , A61K9/0095 , A61K31/185 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/7004 , A61K33/00 , A61K33/06 , A61K33/10 , A61M1/1666 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention said glucose and said at least one magnesium salt, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水，含钠浓缩物和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含葡萄糖，至少一种干酸和至少一种镁盐，以及任选的钾盐和钙盐的粉末组分组成。 根据本发明，所述葡萄糖和所述至少一种镁盐以所述透析酸前体组合物中的无水组分存在。
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公开(公告)号：US10993961B2
公开(公告)日：2021-05-04
申请号：US13805040
申请日：2011-06-20
IPC分类号： A61K33/14 , A61K33/00 , A61K9/00 , A61K31/7004 , A61K33/06 , A61M1/28 , A61K31/19 , A61K31/191 , A61K31/366 , A61K31/385 , A61K31/194 , A61K31/198
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.
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4.发明申请Medical Solution, a Method for Producing Said Medical Solution and Use Thereof 审中-公开医疗解决方案，生产所述医疗解决方案和使用方法公开(公告)号：US20070232796A1
公开(公告)日：2007-10-04
申请号：US10591232
申请日：2005-02-22
申请人： Ola Carlsson , Martin Erixon , Gunita Forsback , Per Kjellstrand , Torbjorn Linden , Anders Wieslander
发明人： Ola Carlsson , Martin Erixon , Gunita Forsback , Per Kjellstrand , Torbjorn Linden , Anders Wieslander
IPC分类号： A61K31/7004 , A61P7/08
CPC分类号： A61K31/7004
摘要： The present invention relates to a medical solution comprising a first single solution containing glucose and/or glucose-like compound. According to the present invention said first single solution has a pH in the range of 1.8-2.6. The present invention further relates to a method for producing said medical solution as well as use thereof.
摘要翻译： 本发明涉及包含含有葡萄糖和/或葡萄糖样化合物的第一单一溶液的医用溶液。 根据本发明，所述第一单溶液的pH在1.8-2.6的范围内。 本发明还涉及一种生产所述医用溶液的方法及其用途。
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5.发明申请Method for preparing a medical solution for the manufacture of a medicament for peritoneal dialysis 审中-公开制备用于腹膜透析的药物的药液的制备方法公开(公告)号：US20060046975A1
公开(公告)日：2006-03-02
申请号：US10538791
申请日：2003-12-10
申请人： Ola Carlsson , Torbjorn Linden , Anders Wieslander
发明人： Ola Carlsson , Torbjorn Linden , Anders Wieslander
CPC分类号： A61M1/287 , A61K31/7008 , A61K31/722 , A61K31/726
摘要： A method for preparing a medical solution, comprising the steps of a) providing a solution comprising one or more acetylated or deacetylated amino sugar/sugars in at least one compartment of a container in a concentration from 15% by weight to 40% by weight, with the basis of the solution in said at least one compartments, and b) terminal sterilisation of said at least one compartment and the contents therein, is disclosed, as well as a solution used for preparing the medical solution, a container containing said solution, and use of said solution for the manufacture of a medicament for peritoneal dialysis.
摘要翻译： 一种制备医用溶液的方法，包括以下步骤：a）在容器的至少一个室中提供浓度为15重量％至40重量％的一种或多种乙酰化或脱乙酰氨基糖/糖的溶液， 其中所述至少一个隔室中的溶液的基础，以及b）所述至少一个隔室及其中的内容物的末端灭菌，以及用于制备医用溶液的溶液，容纳所述溶液的容器， 以及使用所述溶液制造用于腹膜透析的药物。
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公开(公告)号：US09821102B2
公开(公告)日：2017-11-21
申请号：US14128130
申请日：2012-06-11
申请人： Olof Jansson , Torbjorn Linden , Anders Wieslander
发明人： Olof Jansson , Torbjorn Linden , Anders Wieslander
IPC分类号： A61M1/16 , A61K31/7004 , A61K33/06 , A61K33/14 , A61K33/10 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61J1/05
CPC分类号： A61M1/1654 , A61J1/05 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/06 , A61K33/10 , A61K33/14 , A61M1/1666 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
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公开(公告)号：US09138380B2
公开(公告)日：2015-09-22
申请号：US13805557
申请日：2011-06-20
申请人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
发明人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
CPC分类号： A61J1/20 , A61J1/2093 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/287 , B65D31/14 , B65D81/18 , B65D81/20 , B65D81/2007 , B65D81/2023 , B65D81/2046
摘要： A package has a transport/storage state for storing powdery material which is to be mixed with a solvent to form a medical solution. The package includes a compartment which is at least partially defined by two opposing wall portions, and a connector. In the transport/storage state, the compartment contains the powdery material in the form of at least two distinct sets of powdery material of different compositions, where the opposing wall portions are brought into engagement with the powdery material so as to immobilize the sets of powdery material. When used for preparation of the medical solution, a fluid is selectively admitted into the package via the connector so as to expand the compartment and enable mixing of the sets of powdery material with the solvent in the compartment.
摘要翻译： 包装具有用于储存待与溶剂混合以形成医用溶液的粉末状材料的运输/储存状态。 该包装包括至少部分地由两个相对的壁部分限定的隔室和连接器。 在运输/储存状态下，隔室含有至少两组不同组成的粉末状材料形式的粉状材料，其中相对的壁部分与粉末材料接合，从而固定该组粉末状 材料。 当用于制备医用溶液时，通过连接器将流体选择性地进入包装中，以便使隔室膨胀并且使得能够将该组粉末材料与隔室中的溶剂混合。
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公开(公告)号：US20140377376A1
公开(公告)日：2014-12-25
申请号：US14128130
申请日：2012-06-11
申请人： Olof Jansson , Torbjorn Linden , Anders Wieslander
发明人： Olof Jansson , Torbjorn Linden , Anders Wieslander
IPC分类号： A61M1/16 , A61K33/10 , A61K31/7004 , A61K31/194 , A61K31/191 , A61J1/05 , A61K33/06
CPC分类号： A61M1/1654 , A61J1/05 , A61K31/19 , A61K31/191 , A61K31/194 , A61K31/198 , A61K31/366 , A61K31/385 , A61K31/7004 , A61K33/06 , A61K33/10 , A61K33/14 , A61M1/1666 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one calcium salt, and optionally potassium salt, and magnesium salt. According to the invention said glucose and said at least one calcium salt, are present as anhydrous components in said dialysis acid precursor composition.
摘要翻译： 本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水，含钠浓缩物和含碳酸氢盐的浓缩液混合成即用型透析溶液。 所述透析酸前体组合物由包含葡萄糖，至少一种干酸和至少一种钙盐，任选的钾盐和镁盐的粉末组分组成。 根据本发明，所述葡萄糖和所述至少一种钙盐以所述透析酸前体组合物中的无水组分存在。
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9.发明申请Medical Solution, A Method For Producing Said Medical Solution And Use Thereof 有权医疗解决方案，生产所述医疗解决方案及其用途的方法公开(公告)号：US20070298125A1
公开(公告)日：2007-12-27
申请号：US10591233
申请日：2005-02-22
申请人： Malin Ernebrant , Gert-Inge Bertinsson , Torbjorn Linden , Lars-Fride Olsson , Theodor Sandstrom , Therese Svensson , Anders Wieslander
发明人： Malin Ernebrant , Gert-Inge Bertinsson , Torbjorn Linden , Lars-Fride Olsson , Theodor Sandstrom , Therese Svensson , Anders Wieslander
CPC分类号： A61K47/02 , A61K9/0019 , A61K33/00 , A61K33/10 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a medical solution, a method for producing said medical solution, a multi-compartment bag containing the medical solution as well as use of said medical solution. According to the invention the medical solution comprises a first single solution comprising bicarbonate and carbonate in such proportions that the partial pressure of carbon dioxide, CO2, in the first single solution is of the same order of magnitude as the partial pressure of carbon dioxide, CO2, of the atmosphere. The medical solution further comprises a second single solution comprising an acid. Said first and second single solutions are, after terminal sterilization and up on use, to be mixed to form a final solution. Said second single solution has a pH of 1.0-1.5, and said final solution has a pH of 7.0-7.6.
摘要翻译： 本发明涉及医用溶液，所述药液的制造方法，含有所述药液的多室袋以及所述药液的使用。 根据本发明，医用溶液包含包含碳酸氢盐和碳酸盐的第一单一溶液，其比例使第一单一溶液中二氧化碳CO 2分压的量级与 大气的二氧化碳分压CO 2 2。 药物溶液还包含包含酸的第二单一溶液。 所述第一和第二单一解决方案在终端灭菌和使用后被混合以形成最终溶液。 所述第二单溶液的pH为1.0-1.5，所述最终溶液的pH为7.0-7.6。
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公开(公告)号：US20130190681A1
公开(公告)日：2013-07-25
申请号：US13805557
申请日：2011-06-20
申请人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
发明人： Olof Jansson , Lennart Jonsson , Torbjorn Linden , Jan Sternby , Ragnar Tryggvason , Anders Wieslander
CPC分类号： A61J1/20 , A61J1/2093 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/287 , B65D31/14 , B65D81/18 , B65D81/20 , B65D81/2007 , B65D81/2023 , B65D81/2046
摘要： A package has a transport/storage state for storing powdery material which is to be mixed with a solvent to form a medical solution. The package includes a compartment which is at least partially defined by two opposing wall portions, and a connector. In the transport/storage state, the compartment contains the powdery material in the form of at least two distinct sets of powdery material of different compositions, where the opposing wall portions are brought into engagement with the powdery material so as to immobilize the sets of powdery material. When used for preparation of the medical solution, a fluid is selectively admitted into the package via the connector so as to expand the compartment and enable mixing of the sets of powdery material with the solvent in the compartment.
摘要翻译： 包装具有用于储存待与溶剂混合以形成医用溶液的粉末状材料的运输/储存状态。 该包装包括至少部分地由两个相对的壁部分限定的隔室和连接器。 在运输/储存状态下，隔室含有至少两组不同组成的粉末状材料形式的粉状材料，其中相对的壁部分与粉末材料接合，从而固定该组粉末状 材料。 当用于制备医用溶液时，通过连接器将流体选择性地进入包装中，以便使隔室膨胀并且使得能够将该组粉末材料与隔室中的溶剂混合。
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